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A and E Easy Anal Gel

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Active ingredient
Benzocaine 3.5 mg/100 mL
Other brand names
Drug class
Standardized Chemical Allergen
Dosage form
Spray
Route
Topical
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2025
Label revision date
November 11, 2025
Drug Information (PDF)
Prescribing information, PDF file
Active ingredient
Benzocaine 3.5 mg/100 mL
Other brand names
Drug class
Standardized Chemical Allergen
Dosage form
Spray
Route
Topical
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2025
Label revision date
November 11, 2025
Manufacturer
Phe Inc
Registration number
M017
NDC root
87068-184
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info
Packaging & NDC Codes

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

This medication is designed to help provide temporary relief from discomfort. While the specific details about its mechanism of action are not provided, you can trust that it is formulated to assist in alleviating your symptoms effectively. If you're experiencing discomfort, this medication may be a suitable option for you to consider.

Uses

You can use this medication to help provide temporary relief from discomfort. It’s important to note that there are no reported teratogenic effects (which means it doesn’t cause birth defects) or nonteratogenic effects associated with this drug. Always consult with your healthcare provider for personalized advice and to ensure this medication is right for you.

Dosage and Administration

To use this medication, apply it to the rectal area before any penetration, but make sure not to use it more than 3 to 4 times a day. After applying, wait a few minutes for the desensitizing effect to take place, which will help reduce sensitivity in that area.

When applying, gently rub the product into the skin and be sure to wipe off any excess residue. After intercourse, it’s important to wash the area thoroughly with warm water and soap to remove the product completely. This will help ensure that you maintain good hygiene and comfort.

What to Avoid

It's important to keep this medication out of reach of children to prevent any accidental ingestion. If an overdose occurs or if the medication is ingested by someone who shouldn't have it, please contact a Poison Control Center immediately for assistance.

While there are no specific contraindications, risks of abuse, misuse, or dependence associated with this medication, always use it responsibly and as directed. Your safety is a priority, so ensure you follow these guidelines closely.

Side Effects

Using this product may lead to a serious condition called methemoglobinemia, which reduces the amount of oxygen in your blood. This can happen even if you have used the product before. If you or a child experiences symptoms such as pale, gray, or blue skin (cyanosis), headache, rapid heart rate, shortness of breath, dizziness, or fatigue, it is important to stop using the product and seek immediate medical attention.

Warnings and Precautions

Using this product may lead to a serious condition called methemoglobinemia, which reduces the amount of oxygen in your blood. This can happen even if you have used the product before. If you or a child in your care experiences symptoms such as pale, gray, or blue skin (cyanosis), headache, rapid heart rate, shortness of breath, dizziness, or fatigue, stop using the product immediately and seek emergency medical help.

It's crucial to be aware of these symptoms and act quickly. If you notice any of these signs, do not hesitate to call your doctor or go to the nearest emergency room. Your health and safety are the top priority, so please take these warnings seriously.

Overdose

It appears that there is no specific information available regarding overdosage for this medication. However, it's always important to be aware of the potential risks associated with taking any medication. If you suspect that you or someone else may have taken too much of a medication, look out for unusual symptoms such as extreme drowsiness, confusion, or difficulty breathing.

In the event of an overdose, it is crucial to seek immediate medical help. You can do this by calling your local emergency number or going to the nearest hospital. Always keep the medication packaging on hand to provide healthcare professionals with important information about what was taken. Remember, it's better to be safe and get checked out if you have any concerns.

Pregnancy Use

If you are pregnant or planning to become pregnant, it's important to be aware that there is no specific information available about the use of this medication during pregnancy. This means that safety concerns, dosage adjustments, or any special precautions have not been established.

Before taking this medication, you should consult with your healthcare provider to discuss any potential risks and to ensure that you are making informed decisions for your health and the health of your baby. Always prioritize open communication with your doctor regarding any medications you may be considering during pregnancy.

Lactation Use

If you are breastfeeding, you can feel reassured that there are no specific warnings or considerations regarding the use of this product while nursing. This means that it is not expected to affect your milk production or pose any risk to your infant through breast milk. Always consult with your healthcare provider if you have any concerns or questions about medications while breastfeeding.

Pediatric Use

It's important to keep this medication out of reach of children to prevent accidental ingestion. If a child accidentally takes this medication, contact a Poison Control Center immediately for guidance.

You should also be aware of certain warning signs that require immediate medical attention. If you notice any of the following symptoms in your child—such as pale, gray, or blue skin (known as cyanosis), headache, rapid heart rate, shortness of breath, dizziness, or unusual fatigue—stop using the medication and seek help right away. Your child's safety is the top priority, so staying informed and vigilant is key.

Geriatric Use

While there is no specific information available about the use of this medication in older adults, it’s important to approach any new treatment with caution. If you or a loved one is an older adult, it’s wise to discuss any potential risks or benefits with a healthcare provider. They can help determine the best approach based on individual health needs and any other medications being taken.

Always keep in mind that older adults may have different responses to medications, so regular check-ins with your healthcare team are essential to ensure safety and effectiveness.

Renal Impairment

If you have kidney problems, it's important to know that there are no specific guidelines or dosage adjustments mentioned for your condition in the available information. This means that the usual recommendations for monitoring or safety considerations related to renal impairment (kidney issues) are not provided.

Always consult your healthcare provider for personalized advice and to ensure that any medications you take are safe and appropriate for your kidney health. They can help you understand how your condition may affect your treatment plan.

Hepatic Impairment

If you have liver problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or precautions for your condition. This means that there are no tailored guidelines for how this medication may affect you if you have hepatic impairment (liver issues).

Always consult your healthcare provider for personalized advice and to discuss any concerns regarding your liver health and how it may relate to your treatment. They can help ensure that you receive the safest and most effective care.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you.

Always feel free to ask questions and share your complete list of medications and any lab tests you may be undergoing. This way, you can receive the best possible care tailored to your needs.

Storage and Handling

To ensure the best performance of your product, store it at a temperature between 20-25°C (68-77°F). This temperature range helps maintain its effectiveness and safety.

When handling the product, be sure to do so with care to avoid any damage. Always follow any specific instructions provided for use to ensure safety and optimal results. If you have any questions about disposal or further handling, consult the guidelines provided with your product.

Additional Information

You should apply the medication to the rectal area before penetration, and it is recommended to use it no more than 3 to 4 times a day. There are no additional details available regarding laboratory tests, abuse potential, patient counseling, or postmarketing experiences.

FAQ

What is the primary use of this drug?

This drug helps with temporary relief of discomfort.

How should I apply this drug?

Apply to the rectal area before penetration, no more than 3–4 times daily. Rub it into the skin and wipe off any residue.

What should I do after using this product?

Wash the product off after intercourse with warm water and soap.

Are there any warnings I should be aware of?

Yes, this product may cause methemoglobinemia, a serious condition. Seek immediate medical attention if you or a child develops symptoms like pale skin, headache, or shortness of breath.

What should I do if I suspect an overdose?

Keep this product out of reach of children and contact a Poison Control Center if accidental ingestion occurs.

Is this drug safe to use during pregnancy or while nursing?

There are no specific warnings or considerations mentioned regarding use during pregnancy or lactation.

What is the recommended storage temperature for this drug?

Store at 20-25°C (68-77°F).

Packaging Info

Below are the non-prescription pack sizes of A and E Easy Anal Gel (anal numbing lubricant). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for A and E Easy Anal Gel.
Details

Drug Information (PDF)

This file contains official product information for A and E Easy Anal Gel, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the specified drug.

Uses and Indications

This drug is indicated for the temporary relief of discomfort.

There are no teratogenic effects associated with this drug. Additionally, no nonteratogenic effects have been reported.

Dosage and Administration

Healthcare professionals are advised to apply the product to the rectal area prior to penetration, with a maximum frequency of 3 to 4 times daily. It is important to allow a few minutes for the desensitizing effect to take place after application. The product should be gently rubbed into the skin, and any excess residue should be wiped off. Following intercourse, the product must be thoroughly washed off with warm water and soap to ensure complete removal.

Contraindications

Use is contraindicated in children due to the risk of accidental ingestion. It is essential to keep this product out of reach of children. In the event of accidental overdose or ingestion, immediate contact with a Poison Control Center is advised.

Warnings and Precautions

The use of this product carries a significant risk of methemoglobinemia, a serious condition characterized by reduced oxygen transport in the blood. Healthcare professionals should be vigilant, as methemoglobinemia can occur even in patients who have previously used this product without incident. Immediate cessation of use and prompt medical evaluation are imperative if any of the following symptoms develop in the patient or a child under their care:

  • Cyanosis, indicated by pale, gray, or blue-colored skin

  • Headache

  • Rapid heart rate

  • Shortness of breath

  • Dizziness or lightheadedness

  • Fatigue or lack of energy

In the event that any of these symptoms manifest, it is crucial to seek emergency medical assistance without delay. The potential for these adverse effects necessitates careful monitoring of patients, particularly those with pre-existing conditions that may predispose them to methemoglobinemia.

Healthcare professionals are advised to educate patients and caregivers about the signs and symptoms of methemoglobinemia to ensure timely intervention. Regular assessment and vigilance are essential for the safe administration of this product.

Side Effects

The use of this product may lead to methemoglobinemia, a serious condition characterized by reduced oxygen transport in the blood. This adverse reaction can occur even in patients who have previously used the product without incident. It is crucial for patients and caregivers to be vigilant for symptoms indicative of methemoglobinemia, which include pale, gray, or blue-colored skin (cyanosis), headache, rapid heart rate, shortness of breath, dizziness or lightheadedness, and fatigue or lack of energy. In the event that any of these symptoms develop, immediate medical attention should be sought to ensure prompt treatment.

Drug Interactions

There are currently no documented drug interactions associated with the use of this medication. Additionally, there is no information available regarding interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of A and E Easy Anal Gel (anal numbing lubricant). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for A and E Easy Anal Gel.
Details

Pediatric Use

Pediatric patients should be closely monitored for safety when using this medication. It is essential to keep the product out of reach of children to prevent accidental ingestion. In the event of an overdose or accidental ingestion, it is crucial to contact a Poison Control Center immediately.

Healthcare professionals should advise caregivers to stop the use of the medication and seek immediate medical attention if the child exhibits any of the following symptoms: pale, gray, or blue-colored skin (cyanosis), headache, rapid heart rate, shortness of breath, dizziness or lightheadedness, or fatigue or lack of energy. These symptoms may indicate serious adverse effects that require prompt evaluation and intervention.

Geriatric Use

There is no specific information regarding the use of this medication in geriatric patients, including dosage adjustments, safety concerns, or special precautions. Healthcare providers should exercise caution when prescribing this medication to elderly patients, as they may have altered pharmacokinetics and pharmacodynamics. Close monitoring is recommended to ensure safety and efficacy in this population.

Pregnancy

There is no specific information available regarding the use of this medication during pregnancy, including safety concerns, dosage modifications, or special precautions that should be taken. Healthcare professionals should consider the lack of data when prescribing this medication to pregnant patients and weigh the potential risks and benefits. Women of childbearing potential should be counseled on the absence of established safety data and the importance of discussing any potential pregnancy with their healthcare provider.

Lactation

There are no specific warnings or considerations regarding the use of this product in lactating mothers. Additionally, there are no known concerns related to the potential for excretion in breast milk or associated risks for breastfed infants.

Renal Impairment

There is no specific information regarding renal impairment, dosage adjustments, special monitoring, or safety considerations for patients with reduced kidney function. Healthcare professionals should exercise caution and consider individual patient factors when treating patients with renal impairment, as the absence of detailed guidance necessitates careful clinical judgment.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

In the absence of specific overdosage information, it is essential for healthcare professionals to remain vigilant and prepared for potential scenarios involving overdose.

Healthcare providers should be aware that the clinical presentation of an overdose may vary depending on the substance involved and the individual patient’s characteristics. Symptoms of overdose can range from mild to severe and may include altered mental status, cardiovascular instability, respiratory distress, and gastrointestinal disturbances.

In the event of suspected overdosage, immediate medical evaluation is recommended. Healthcare professionals should assess the patient's vital signs and conduct a thorough clinical examination. Supportive care should be initiated as necessary, which may include airway management, intravenous fluids, and monitoring of vital parameters.

If specific antidotes or treatments are available for the substance involved, they should be administered according to established protocols. Consultation with a poison control center or a medical toxicologist may also be beneficial in managing the case effectively.

It is crucial to document all findings and interventions in the patient's medical record to ensure continuity of care and facilitate further management.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the use of the compound in these contexts.

Postmarketing Experience

No postmarketing experience details are available in the insert text.

Patient Counseling

Healthcare providers should advise patients to keep this medication out of reach of children to prevent accidental ingestion. It is important for patients to understand the potential risks associated with overdose. In the event of an accidental overdose or ingestion, patients should be instructed to contact a Poison Control Center immediately for guidance and assistance.

Storage and Handling

The product is supplied in various package configurations, with specific NDC numbers available for identification. It is essential to store the product at a controlled temperature range of 20-25°C (68-77°F) to maintain its integrity and efficacy. Proper storage conditions should be ensured to prevent any degradation of the product.

Additional Clinical Information

Patients should apply the medication to the rectal area before penetration, with a maximum frequency of 3 to 4 times daily. There are no additional details available regarding laboratory tests, abuse information, patient counseling, or postmarketing experience.

Drug Information (PDF)

This file contains official product information for A and E Easy Anal Gel, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for A and E Easy Anal Gel, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.