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Sinus Pressure, Pain and Cough

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Active ingredients
  • Acetaminophen 325 mg
  • Guaifenesin 200 mg
  • Dextromethorphan Hydrobromide 10 mg
  • Phenylephrine Hydrochloride 5 mg
Other brand names
Drug classes
Expectorant, Sigma-1 Agonist, Uncompetitive N-methyl-D-aspartate Receptor Antagonist, alpha-1 Adrenergic Agonist
Dosage form
Tablet, Film Coated
Route
Oral
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2024
Label revision date
November 15, 2025
Drug Information (PDF)
Prescribing information, PDF file
Active ingredients
  • Acetaminophen 325 mg
  • Guaifenesin 200 mg
  • Dextromethorphan Hydrobromide 10 mg
  • Phenylephrine Hydrochloride 5 mg
Other brand names
Drug classes
Expectorant, Sigma-1 Agonist, Uncompetitive N-methyl-D-aspartate Receptor Antagonist, alpha-1 Adrenergic Agonist
Dosage form
Tablet, Film Coated
Route
Oral
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2024
Label revision date
November 15, 2025
Manufacturer
Meijer Distribution, Inc.
Registration number
M012
NDC root
79481-6172
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info
Packaging & NDC Codes

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

Meijer® is a multi-symptom medication designed to provide temporary relief from various symptoms associated with the common cold and sinus issues. It contains active ingredients such as acetaminophen (a pain reliever), dextromethorphan HBr (a cough suppressant), guaifenesin (an expectorant that helps loosen mucus), and phenylephrine HCl (a nasal decongestant). This combination works to alleviate headaches, coughs, nasal congestion, and sinus pressure, while also helping to thin bronchial secretions, making coughs more productive.

By promoting nasal and sinus drainage, Meijer® aims to ease discomfort and improve breathing when you're feeling under the weather. It's formulated to address multiple symptoms, making it a convenient option for those seeking relief from cold-related ailments.

Uses

You can use this medication to temporarily relieve various discomforts, including headaches, coughs caused by the common cold, and nasal or sinus congestion. It also helps alleviate pressure in your sinuses and eases minor aches and pains.

Additionally, this medication works to loosen phlegm (a thick mucus) and thin bronchial secretions, making it easier to clear out mucus from your airways, which can help make your coughs more productive. It also promotes drainage in your nasal passages and sinuses, providing further relief from congestion.

Dosage and Administration

It's important to follow the dosage instructions carefully to ensure your safety. For adults and children aged 12 years and older, you should take 2 caplets every 4 hours as needed. However, make sure not to exceed 12 caplets in a 24-hour period.

If you are caring for a child under 12 years old, do not use this medication for them. Always stick to the recommended dosage and avoid taking more than directed to prevent any potential health risks.

What to Avoid

You should avoid using this product if you are currently taking any other medication that contains acetaminophen, whether it's a prescription or over-the-counter drug. If you're unsure about a medication, it's best to consult with your doctor or pharmacist. Additionally, do not use this product if you are taking a prescription monoamine oxidase inhibitor (MAOI) for conditions like depression or Parkinson’s disease, or if you have stopped taking an MAOI within the last two weeks. Again, if you're uncertain about your medications, please ask a healthcare professional.

It's also important not to use this product if you have ever experienced an allergic reaction to it or any of its ingredients. Taking these precautions can help ensure your safety and well-being.

Side Effects

This product contains acetaminophen, which can lead to severe liver damage if you exceed 4,000 mg in 24 hours, take it with other acetaminophen-containing medications, or consume three or more alcoholic drinks daily while using it. Additionally, be aware that acetaminophen may cause serious skin reactions, including blisters, rash, and skin reddening. If you notice any skin reactions, stop using the product and seek medical help immediately.

You should stop using this product and consult a doctor if you experience nervousness, dizziness, or sleeplessness, if your pain, nasal congestion, or cough worsens or lasts more than seven days, or if your fever lasts more than three days. Other concerning signs include redness or swelling, new symptoms, or a cough that returns with a rash or headache. It's important to talk to a doctor before using this product if you have liver disease, diabetes, heart disease, thyroid disease, high blood pressure, or other specific health conditions. If you are taking the blood thinner warfarin, consult a doctor or pharmacist before use.

Warnings and Precautions

This product contains acetaminophen, which can lead to severe liver damage if you take more than 4,000 mg in 24 hours, use it with other medications containing acetaminophen, or consume three or more alcoholic drinks daily while using it. Be aware that acetaminophen may also cause serious skin reactions, such as blisters, rash, or skin reddening. If you experience any skin reactions, stop using the product and seek medical help immediately.

Before using this product, consult your doctor if you have liver disease, diabetes, heart disease, thyroid disease, high blood pressure, or if you have a persistent cough, especially if it produces mucus. It's also important to talk to your doctor or pharmacist if you are taking the blood thinner warfarin. If you suspect an overdose, seek emergency medical assistance or contact a Poison Control Center right away, even if you don’t notice any symptoms.

You should stop using this product and call your doctor if you experience nervousness, dizziness, or sleeplessness, if your pain, nasal congestion, or cough worsens or lasts more than seven days, if your fever worsens or lasts more than three days, or if you notice redness or swelling. New symptoms or a cough that returns with a rash or headache that lasts could indicate a serious condition, so it’s important to get medical advice in these situations.

Overdose

If you suspect an overdose, it’s important to seek medical help immediately or contact a Poison Control Center. This is crucial for both adults and children, even if you don’t see any signs or symptoms of an overdose.

Signs of an overdose can vary, but they may include unusual drowsiness, confusion, or difficulty breathing. Remember, acting quickly can make a significant difference, so don’t hesitate to get help.

Pregnancy Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using this medication. They can provide guidance on whether it’s safe for you and your baby. Always prioritize your health and the health of your child by seeking expert advice.

Lactation Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using any medication. This ensures that you understand any potential risks and can make informed decisions about your health and the health of your baby. Always prioritize open communication with your doctor regarding your breastfeeding journey.

Pediatric Use

If you are considering this medication for your child, it's important to know that it should not be used in children under 12 years old. For those aged 12 and older, the recommended dosage is 2 caplets every 4 hours, but be careful not to exceed 12 caplets in a 24-hour period.

In the event of an overdose, it's crucial to seek medical help immediately or contact a Poison Control Center. Quick medical attention is essential for both adults and children, even if there are no noticeable signs or symptoms. Always prioritize safety when administering medication to your child.

Geriatric Use

While there is no specific information available about the use of this medication in older adults, it’s important to approach any new treatment with caution. If you or a loved one is an older adult, it’s always wise to discuss any medications with a healthcare provider, especially since older individuals may have different health needs and responses to treatments.

Since there are no dosage adjustments or safety concerns specifically noted for elderly patients, your healthcare provider can help determine the best approach based on individual health conditions and any other medications being taken. Always prioritize open communication with your doctor to ensure safe and effective use of any medication.

Renal Impairment

If you have kidney problems, it's important to consult your doctor before using this medication, especially if you experience difficulty urinating due to an enlarged prostate gland. Your healthcare provider can help determine if this medication is safe for you and may suggest adjustments to your dosage or monitoring based on your kidney function. Always prioritize open communication with your doctor regarding your kidney health and any medications you are considering.

Hepatic Impairment

If you have liver problems, it's important to be cautious when using products that contain acetaminophen. Taking more than 4,000 mg of acetaminophen in a 24-hour period, using other medications that also contain acetaminophen, or consuming three or more alcoholic drinks daily while using this product can lead to severe liver damage.

Before using this product, you should consult with your doctor if you have liver disease. They can provide guidance on safe usage and any necessary adjustments to your dosage. Your health and safety are the top priority, so don’t hesitate to seek professional advice.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. Currently, there are no specific drug interactions or laboratory test interactions noted for this medication. However, every individual’s health situation is unique, and your provider can help ensure that your treatment plan is safe and effective for you. Always feel free to ask questions and share all the medications and supplements you are using to avoid any potential issues.

Storage and Handling

To ensure the best performance and safety of your product, store it at room temperature, ideally around 25°C (77°F). It can safely be kept in a range from 15°C to 30°C (59°F to 86°F). Always check the outer package before use; if it is opened or if the blister is torn or broken, do not use the product. Additionally, make sure to look at the end flap for important information like the expiration date and lot number, which are essential for tracking the product's safety and effectiveness.

Additional Information

You should take this medication orally. If you are pregnant or breastfeeding, it's important to consult with a healthcare professional before using this medication to ensure it's safe for you and your baby.

Additionally, if you're concerned about the potential for medicine abuse, especially among teens, you can find helpful resources at www.StopMedicineAbuse.org.

FAQ

What is Meijer® used for?

Meijer® is used to temporarily relieve headache, cough due to the common cold, nasal congestion, sinus congestion and pressure, and minor aches and pains.

What are the active ingredients in Meijer®?

The active ingredients in Meijer® are acetaminophen, dextromethorphan HBr, guaifenesin, and phenylephrine HCl.

What should I do if I experience severe skin reactions?

If you experience severe skin reactions such as blisters, rash, or skin reddening, stop using Meijer® and seek medical help immediately.

What is the maximum dosage for adults and children over 12?

Adults and children 12 years and over should take 2 caplets every 4 hours, with a maximum of 12 caplets in any 24-hour period.

Are there any contraindications for using Meijer®?

Do not use Meijer® if you are taking any other drug containing acetaminophen, if you are on a prescription monoamine oxidase inhibitor (MAOI), or if you have had an allergic reaction to this product or its ingredients.

What should I do in case of overdose?

In case of overdose, get medical help or contact a Poison Control Center right away, as prompt medical attention is critical.

Can I use Meijer® if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, ask a health professional before using Meijer®.

What are the storage instructions for Meijer®?

Store Meijer® at 25°C (77°F), with permitted excursions between 15°-30°C (59°-86°F).

Packaging Info

Below are the non-prescription pack sizes of Sinus Pressure, Pain and Cough (acetaminophen, dextromethorphan hbr, guaifenesin, phenylephrine hcl). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Sinus Pressure, Pain and Cough.
Details

Drug Information (PDF)

This file contains official product information for Sinus Pressure, Pain and Cough, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the specified drug.

Uses and Indications

This drug is indicated for the temporary relief of headache, cough due to the common cold, nasal congestion, sinus congestion and pressure, as well as minor aches and pains. It aids in loosening phlegm (mucus) and thinning bronchial secretions, facilitating the clearance of mucus from the bronchial passageways and making coughs more productive. Additionally, it temporarily promotes nasal and/or sinus drainage.

There are no teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

Patients should adhere strictly to the recommended dosage. For adults and children aged 12 years and older, the prescribed dosage is 2 caplets every 4 hours as needed. It is imperative that patients do not exceed 12 caplets within a 24-hour period.

The use of this medication is not recommended for children under 12 years of age. Healthcare professionals should ensure that patients are aware of these guidelines to prevent potential overdose and ensure safe administration.

Contraindications

Use of this product is contraindicated in the following situations:

  • Concurrent use with any other drug containing acetaminophen, whether prescription or nonprescription, due to the risk of acetaminophen overdose. If there is uncertainty regarding the presence of acetaminophen in other medications, consultation with a healthcare professional is advised.

  • In patients currently taking a prescription monoamine oxidase inhibitor (MAOI) or within 2 weeks of discontinuing such treatment. MAOIs are commonly prescribed for depression, psychiatric, or emotional conditions, as well as for Parkinson’s disease. If there is uncertainty about the presence of an MAOI in a prescription, a healthcare professional should be consulted prior to use.

  • In individuals with a history of allergic reactions to this product or any of its ingredients, to prevent potential severe allergic responses.

Warnings and Precautions

This product contains acetaminophen, which carries a significant risk of severe liver damage if not used according to the guidelines. Healthcare professionals should advise patients that the risk of liver injury increases with the following conditions: exceeding 4,000 mg of acetaminophen within a 24-hour period, concurrent use with other medications containing acetaminophen, or consumption of three or more alcoholic beverages daily while using this product.

Acetaminophen may also provoke severe skin reactions, which can manifest as blisters, rash, or skin reddening. In the event of any skin reaction, patients must be instructed to discontinue use immediately and seek medical assistance.

Before recommending this product, healthcare providers should inquire about the patient's medical history. It is particularly important to consult a physician if the patient has any of the following conditions: liver disease, diabetes, heart disease, thyroid disease, persistent or chronic cough (such as that associated with smoking, asthma, chronic bronchitis, or emphysema), high blood pressure, cough accompanied by excessive phlegm, or difficulty urinating due to prostate enlargement. Additionally, patients taking the anticoagulant warfarin should consult a healthcare professional prior to use.

In cases of overdose, immediate medical attention is essential. Patients should be advised to contact a Poison Control Center or seek emergency medical help without delay, even if no symptoms are apparent, as prompt intervention is critical for both adults and children.

Patients should be instructed to discontinue use and consult a healthcare provider if they experience nervousness, dizziness, or sleeplessness; if pain, nasal congestion, or cough worsens or persists beyond seven days; if fever intensifies or lasts more than three days; if redness or swelling occurs; if new symptoms develop; or if a cough recurs alongside a rash or headache that persists. These symptoms may indicate a serious underlying condition that requires further evaluation.

Side Effects

Severe adverse reactions associated with this product include significant liver damage, which may occur if patients exceed 4,000 mg of acetaminophen within a 24-hour period, use other medications containing acetaminophen concurrently, or consume three or more alcoholic beverages daily while using this product.

Patients should be aware of the potential for severe skin reactions, which may manifest as blisters, rash, or skin reddening. In the event of a skin reaction, it is imperative to discontinue use and seek medical assistance immediately.

Common adverse reactions warranting medical consultation include nervousness, dizziness, or sleeplessness. Patients should also stop use and consult a healthcare provider if pain, nasal congestion, or cough worsens or persists beyond seven days, if fever intensifies or lasts more than three days, if redness or swelling occurs, if new symptoms arise, or if a cough recurs alongside a rash or headache that lasts. These symptoms may indicate a serious underlying condition.

Prior to using this product, patients with liver disease, diabetes, heart disease, thyroid disease, persistent or chronic cough (such as that associated with smoking, asthma, chronic bronchitis, or emphysema), high blood pressure, cough accompanied by excessive phlegm, or difficulty urinating due to prostate gland enlargement should consult a healthcare professional. Additionally, patients taking the anticoagulant warfarin should seek advice from a doctor or pharmacist before use.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there is no information available regarding interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Sinus Pressure, Pain and Cough (acetaminophen, dextromethorphan hbr, guaifenesin, phenylephrine hcl). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Sinus Pressure, Pain and Cough.
Details

Pediatric Use

Pediatric patients under 12 years of age should not use this medication. For adolescents aged 12 years and older, the recommended dosage is 2 caplets every 4 hours, with a maximum of 12 caplets in any 24-hour period. In the event of an overdose, it is crucial to seek medical assistance or contact a Poison Control Center immediately, as prompt medical attention is essential for both adults and children, regardless of the presence of signs or symptoms.

Geriatric Use

There is no specific information available regarding the use of this medication in geriatric patients, including dosage adjustments, safety concerns, or special precautions. Healthcare providers should exercise caution when prescribing this medication to elderly patients, as individual responses may vary. Monitoring for potential adverse effects and therapeutic efficacy is recommended in this population.

Pregnancy

Pregnant patients and those who are breastfeeding should consult a healthcare professional prior to using this medication. The potential risks and benefits must be carefully weighed, as the effects on fetal outcomes and lactation are not fully established. It is essential for women of childbearing potential to seek medical advice to ensure the safety of both the mother and the developing fetus or nursing infant.

Lactation

Lactating mothers are advised to consult a health professional prior to using this medication. There is currently no available data regarding the excretion of this drug in human breast milk or its effects on breastfed infants. Therefore, caution is recommended when administering this medication to lactating individuals.

Renal Impairment

Patients with renal impairment should consult a healthcare professional prior to use, particularly if they experience difficulty in urination due to enlargement of the prostate gland. It is essential to assess renal function and consider potential dosing adjustments or monitoring requirements based on the degree of impairment.

Hepatic Impairment

Patients with hepatic impairment should exercise caution when using this product, as it contains acetaminophen, which is associated with the risk of severe liver damage. It is critical that patients do not exceed a maximum dosage of 4,000 mg of acetaminophen within a 24-hour period. Additionally, the concurrent use of other medications containing acetaminophen or the consumption of three or more alcoholic drinks daily while using this product may further increase the risk of liver damage.

Patients with known liver disease are advised to consult a healthcare professional prior to using this product to assess the appropriateness of treatment and to discuss potential risks. Monitoring of liver function may be warranted in these patients to ensure safety and efficacy during treatment.

Overdosage

In the event of an overdose, it is imperative to seek immediate medical assistance or contact a Poison Control Center without delay. Prompt medical attention is crucial for both adults and children, even in the absence of noticeable signs or symptoms.

Healthcare professionals should be aware that the lack of immediate symptoms does not preclude the potential for serious health consequences. Therefore, it is essential to monitor the patient closely and provide appropriate interventions as necessary.

Nonclinical Toxicology

There is currently no available information regarding teratogenic effects. Additionally, no data has been provided concerning non-teratogenic effects. The nonclinical toxicology section does not contain any relevant information at this time. Furthermore, there is no information available related to animal pharmacology and toxicology.

Postmarketing Experience

Postmarketing experience has identified the following adverse reactions associated with acetaminophen use: severe skin reactions, including blisters, rash, and skin reddening. These events have been reported voluntarily or through surveillance programs.

Patient Counseling

Healthcare providers should advise patients to seek immediate medical assistance or contact a Poison Control Center in the event of an overdose, emphasizing that prompt medical attention is crucial for both adults and children, even if no signs or symptoms are apparent.

Patients should be instructed not to exceed the recommended dosage to avoid potential adverse effects. It is important for healthcare providers to encourage patients to consult with a doctor before using the medication if they have any of the following conditions: liver disease, diabetes, heart disease, thyroid disease, a persistent or chronic cough (such as that associated with smoking, asthma, chronic bronchitis, or emphysema), high blood pressure, a cough that produces excessive phlegm (mucus), or difficulty urinating due to an enlarged prostate gland.

Additionally, patients should be advised to speak with a doctor or pharmacist prior to use if they are currently taking the blood-thinning medication warfarin, as this may require special consideration.

Storage and Handling

The product is supplied in a tamper-evident package. It should not be used if the outer package is opened or if the blister is torn or broken. The recommended storage temperature is 25°C (77°F), with permissible excursions between 15°-30°C (59°-86°F). Healthcare professionals are advised to check the end flap of the package for the expiration date and lot number to ensure product integrity and safety.

Additional Clinical Information

Patients should be informed that the medication is administered orally. Clinicians are advised to counsel patients regarding the importance of consulting a healthcare professional if they are pregnant or breastfeeding before using the medication.

Additionally, it is important to raise awareness about the potential for medicine abuse among teens, and resources such as www.StopMedicineAbuse.org can provide further information on this topic. No further details are available regarding laboratory tests or postmarketing experiences.

Drug Information (PDF)

This file contains official product information for Sinus Pressure, Pain and Cough, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Sinus Pressure, Pain and Cough, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

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Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.