Afrin No Drip Night

Description

Oxymetazoline HCl is a nasal solution formulated as a nasal decongestant. It is presented in a 1/2 FL OZ (15 mL) pump mist delivery system, designed to provide instant relief from nasal congestion associated with colds and allergies. The product features a soothing chamomile scent and is characterized by its NoDrip technology, which prevents dripping from the nose or down the throat. This formulation offers up to 12 hours of relief and is the #1 doctor-recommended nasal decongestant spray.

Uses and Indications

This drug is indicated for the temporary relief of nasal congestion associated with the common cold, hay fever, and upper respiratory allergies. It acts by shrinking swollen nasal membranes, thereby facilitating easier breathing. Additionally, this drug provides temporary relief from sinus congestion and pressure.

There are no teratogenic or nonteratogenic effects mentioned in the available data.

Dosage and Administration

Adults and children aged 6 to under 12 years of age, when administered under adult supervision, may receive 2 or 3 sprays in each nostril. Dosing should not occur more frequently than every 10 to 12 hours, and it is important not to exceed 2 doses within a 24-hour period. For children under 6 years of age, consultation with a healthcare professional is advised prior to use.

To prepare the medication for administration, the bottle should be shaken well before use. The user should hold the white tabs, press the grooved area of the cap firmly, and turn it counterclockwise. Prior to the initial use, the metered pump must be primed by firmly depressing the pump several times. For the actual spraying, the bottle should be held with the thumb at the base and the nozzle positioned between the first and second fingers. The nozzle should be inserted into the nostril without tilting the head. A firm, even stroke should be used to fully depress the rim while simultaneously sniffing deeply. After use, the nozzle should be wiped clean, and the cap should be secured.

Contraindications

There are no specific contraindications identified for this product. However, it is essential to adhere to the following usage guidelines: do not exceed the recommended dosage, and do not use the product for more than three consecutive days. Use only as directed to ensure safety and efficacy.

Warnings and Precautions

Patients should consult a healthcare professional prior to use if they have a history of heart disease, high blood pressure, thyroid disease, diabetes, or difficulty urinating due to an enlarged prostate gland. These conditions may increase the risk of adverse effects and require careful consideration before initiating treatment.

In the event that symptoms persist despite use, it is imperative to discontinue use and seek medical advice. Persistent symptoms may indicate an underlying condition that necessitates further evaluation and management.

This product should be kept out of reach of children. In the case of accidental ingestion, immediate medical assistance should be sought, or contact with a Poison Control Center is advised to ensure appropriate care is provided.

Side Effects

Patients should be aware of several important warnings and potential adverse reactions associated with the use of this product. Individuals with pre-existing conditions such as heart disease, high blood pressure, thyroid disease, diabetes, or those experiencing trouble urinating due to an enlarged prostate gland should consult a healthcare professional before use.

During the use of this product, participants may experience temporary discomfort, which can include burning, stinging, sneezing, or an increase in nasal discharge. Additionally, frequent or prolonged use may lead to a recurrence or worsening of nasal congestion. It is also important to note that sharing this product among multiple users may increase the risk of spreading infections.

Patients are advised to discontinue use and seek medical advice if symptoms persist. Special caution is warranted for pregnant or breastfeeding individuals, who should consult a health professional prior to use.

Furthermore, this product should be kept out of reach of children. In the event of accidental ingestion, immediate medical assistance should be sought or contact with a Poison Control Center is recommended.

Drug Interactions

There are no specific drug interactions or laboratory test interactions identified in the available data. Therefore, no recommendations for dosage adjustments or monitoring are necessary at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Afrin No Drip Night (oxymetazoline hydrochloride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Pediatric Use

Pediatric patients under 6 years of age should consult a healthcare professional before use. For children aged 6 to under 12 years, the recommended dosage is 2 or 3 sprays in each nostril, administered no more frequently than every 10 to 12 hours. It is important not to exceed 2 doses within a 24-hour period. Adult supervision is advised during administration for this age group.

Geriatric Use

Elderly patients may not have specific information regarding the use of this medication, as the prescribing information does not provide any age considerations, dosage adjustments, or safety concerns pertinent to this population. Consequently, healthcare providers should exercise clinical judgment when prescribing this medication to geriatric patients, as individual patient factors may influence treatment outcomes. Monitoring for efficacy and safety is advised, given the absence of tailored recommendations for elderly patients.

Pregnancy

Pregnant patients and those who are breastfeeding should consult a healthcare professional prior to using this medication. It is essential to evaluate the potential risks and benefits associated with its use during pregnancy and lactation.

Lactation

Lactating mothers are advised to consult a health professional prior to using this medication. There is no specific data available regarding the excretion of this medication in breast milk or its effects on breastfed infants. Therefore, caution is recommended when administering this medication to lactating individuals.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the drug insert regarding dosage adjustments, special monitoring, or safety considerations. Therefore, healthcare professionals should exercise caution when prescribing this medication to individuals with reduced kidney function, as the absence of detailed guidance necessitates careful clinical judgment. Regular monitoring of renal function may be advisable in these patients to ensure safety and efficacy.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to this medication. Consequently, there are no dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the prescribing information.

Overdosage

In the event of an overdosage, immediate medical intervention is crucial. If the substance is ingested, it is imperative to seek medical assistance or contact a Poison Control Center without delay.

Healthcare professionals should be aware that prompt action can significantly influence the outcome of an overdosage situation. Symptoms of overdosage may vary depending on the specific substance involved; therefore, a thorough assessment and monitoring of the patient are essential.

Management procedures may include supportive care and symptomatic treatment as necessary. It is recommended that healthcare providers follow established protocols for the management of overdosage, which may involve the administration of activated charcoal, intravenous fluids, or other interventions based on the clinical presentation and severity of symptoms.

In all cases of suspected overdosage, the involvement of a Poison Control Center can provide valuable guidance on the appropriate management strategies tailored to the specific circumstances of the case.

Nonclinical Toxicology

If pregnant or breastfeeding, it is advised to consult a health professional prior to use. Temporary discomfort may occur, including symptoms such as burning, stinging, sneezing, or an increase in nasal discharge. No additional relevant information regarding nonclinical toxicology or animal pharmacology and toxicology has been identified.

Postmarketing Experience

Postmarketing experience has revealed reports of several adverse reactions associated with the use of the product. These include burning, stinging, sneezing, and an increase in nasal discharge. These events were reported voluntarily or identified through surveillance programs.

Patient Counseling

Healthcare providers should advise patients to keep this product out of reach of children to prevent accidental ingestion. Instruct patients that if the product is swallowed, they should seek medical help or contact a Poison Control Center immediately.

Patients should be informed to stop using the product and consult a doctor if symptoms persist. It is important to emphasize that when using this product, patients must not exceed the recommended dosage and should not use it for more than three consecutive days. They should use the product only as directed to avoid potential complications.

Healthcare providers should also discuss the possibility of frequent or prolonged use leading to a recurrence or worsening of nasal congestion. Patients may experience temporary discomfort, including burning, stinging, sneezing, or an increase in nasal discharge during use.

Finally, it is crucial to inform patients that the use of this container by more than one person may increase the risk of spreading infection.

Storage and Handling

The product is supplied in packaging that includes specific NDC numbers, which should be referenced for identification. It is essential to store the product at a controlled temperature between 20º to 25ºC (68º to 77ºF) to maintain its integrity and efficacy.

Healthcare professionals are advised to retain the carton for future reference, as it contains important information regarding the full labeling of the product. Proper handling and storage conditions are crucial to ensure the product remains effective throughout its shelf life.

Additional Clinical Information

No further data are available.

Drug Information (PDF)

This file contains official product information for Afrin No Drip Night, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)