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Alka-Seltzer Cool Action Extra Strength Reliefchews Mint

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Active ingredient
Calcium Carbonate 750 mg
Other brand names
Drug classes
Blood Coagulation Factor, Phosphate Binder
Dosage form
Tablet, Chewable
Route
Oral
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2019
Label revision date
December 4, 2025
Drug Information (PDF)
Prescribing information, PDF file
Active ingredient
Calcium Carbonate 750 mg
Other brand names
Drug classes
Blood Coagulation Factor, Phosphate Binder
Dosage form
Tablet, Chewable
Route
Oral
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2019
Label revision date
December 4, 2025
Manufacturer
Bayer HealthCare LLC.
Registration number
M001
NDC root
0280-0058
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info (2 NDCs)
Packaging & NDC Codes (2)

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

Alka-Seltzer® is an antacid that contains calcium carbonate, which works by neutralizing stomach acid quickly, often within seconds. It is designed to provide relief from common digestive discomforts such as acid indigestion, heartburn, sour stomach, and upset stomach associated with these symptoms.

This product is available in an extra strength formula and comes in a cool mint flavor, making it a pleasant option for those seeking quick relief. Alka-Seltzer® is offered in the form of chewable tablets, allowing for easy consumption.

Uses

If you're experiencing discomfort from acid indigestion, heartburn, sour stomach, or an upset stomach related to these symptoms, this medication can help provide relief. It’s designed to ease the discomfort associated with these common digestive issues, allowing you to feel more comfortable throughout your day.

Rest assured, there are no known teratogenic effects (which means it doesn't cause birth defects) or nonteratogenic effects associated with this medication. This makes it a safe option for those looking to alleviate their stomach-related discomfort.

Dosage and Administration

If you are an adult or a child aged 12 years and older, you can take 2 to 4 chewable tablets when you experience symptoms, or as your doctor advises. Make sure to fully chew the tablets before swallowing them. However, it's important not to exceed 5 chewable tablets in a 24-hour period to avoid any potential issues.

For children under 12 years old, it's best to consult a doctor before giving them any chewable tablets. If you are pregnant, you should also limit your intake to no more than 5 chewable tablets in a 24-hour period. Always follow these guidelines to ensure safe and effective use of the medication.

What to Avoid

You should avoid using this product if you have ever had an allergic reaction to it or any of its ingredients. It's important to follow the recommended dosage carefully: do not take more than 5 chewable tablets in a 24-hour period. If you are pregnant, the same limit applies. Additionally, do not use the maximum dosage for more than 2 weeks unless your doctor advises you to do so.

Be mindful that misuse or exceeding the recommended dosage can lead to serious health issues, including dependence (a condition where your body becomes reliant on a substance). Always prioritize your safety and consult with a healthcare professional if you have any questions or concerns.

Side Effects

It's important to be aware of potential side effects when considering this medication. You should not use this product if you have ever experienced an allergic reaction to it or any of its ingredients. Allergic reactions can range from mild symptoms, like rashes, to severe reactions that may require immediate medical attention.

Always consult with your healthcare provider if you have any concerns about allergies or side effects related to this medication. Your safety is a priority, and understanding these warnings can help you make informed decisions about your health.

Warnings and Precautions

You should not use this product if you have ever had an allergic reaction to it or any of its ingredients. Before using it, consult with your doctor or pharmacist, especially if you are currently taking any prescription medications, as antacids can interact with certain drugs.

When using this product, remember to limit yourself to a maximum of 5 chewable tablets in a 24-hour period. If you are pregnant, do not exceed this dosage, and avoid using the maximum dosage for more than 2 weeks unless directed by a physician. If you are pregnant or breastfeeding, make sure to inform your doctor that you are using this product. Always keep it out of reach of children.

Overdose

It appears that there is no specific information available regarding overdosage for this medication. However, it’s always important to be aware of the signs of an overdose, which can include unusual drowsiness, confusion, or difficulty breathing. If you suspect an overdose, it’s crucial to seek immediate medical help.

In case of an emergency, contact your local poison control center or go to the nearest hospital. Always keep medications out of reach of children and follow the prescribed dosage to prevent any potential risks. If you have any concerns or questions about your medication, don’t hesitate to reach out to your healthcare provider for guidance.

Pregnancy Use

If you are pregnant or breastfeeding, it’s important to let your doctor know that you are using this product. This information helps your healthcare provider assess any potential risks and make the best decisions for your health and the health of your baby. Always prioritize open communication with your doctor regarding any medications or treatments you are using during this time.

Lactation Use

If you are pregnant or breastfeeding, it's important to let your doctor know that you are using this product. This information helps ensure your safety and the well-being of your baby. Always consult with your healthcare provider about any medications or products you are using while nursing, as they can provide guidance tailored to your specific situation.

Pediatric Use

If you have a child under 12 years old, it's important to consult a doctor before giving them this medication. For children aged 12 and older, they can take 2 to 4 chewable tablets as needed for symptoms, but they should fully chew and then swallow the tablets. Always follow your doctor's guidance regarding dosage and usage.

Geriatric Use

When it comes to using this medication in older adults, there is no specific information available about dosage adjustments, safety concerns, or special precautions. This means that healthcare providers may not have tailored guidelines for elderly patients.

If you or a loved one is an older adult considering this medication, it’s important to discuss any potential risks and benefits with your healthcare provider. They can help determine the best approach based on individual health needs and conditions. Always prioritize open communication with your doctor to ensure safe and effective treatment.

Renal Impairment

If you have kidney problems, it's important to know that the information provided does not include specific guidelines for dosage adjustments, special monitoring, or safety considerations related to renal impairment (kidney issues). This means that there are no tailored recommendations for how your treatment may need to change based on your kidney function.

Always consult your healthcare provider for personalized advice and to ensure that your treatment plan is safe and effective for your specific situation. They can help monitor your kidney health and make any necessary adjustments to your medications.

Hepatic Impairment

If you have liver problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or precautions for your condition. This means that there are no tailored guidelines for how this medication may affect you if you have hepatic impairment (issues with liver function).

Always consult your healthcare provider for personalized advice and to ensure that any medication you take is safe and appropriate for your liver health. They can help monitor your condition and make any necessary adjustments to your treatment plan.

Drug Interactions

It's important to be aware that some over-the-counter medications, such as antacids containing calcium carbonate, can interact with certain prescription drugs. This interaction may affect how well those medications work in your body. Because of this, it's crucial to discuss all the medications you are taking, including any antacids, with your healthcare provider. They can help ensure that your treatments are safe and effective.

Always keep your healthcare provider informed about any changes in your medication routine, as they can provide guidance tailored to your specific health needs.

Storage and Handling

To ensure the best performance of your product, store it at room temperature, keeping it away from excessive heat (above 40ºC or 104ºF) and humidity. These conditions can affect its effectiveness. After each use, make sure to close the cap tightly to maintain its integrity and prevent contamination.

By following these simple storage and handling guidelines, you can help ensure that your product remains safe and effective for your needs.

Additional Information

No further information is available.

FAQ

What is Alka-Seltzer® used for?

Alka-Seltzer® is used for the relief of acid indigestion, heartburn, sour stomach, and upset stomach associated with these symptoms.

How should I take Alka-Seltzer®?

Adults and children 12 years and over should fully chew then swallow 2 to 4 chewable tablets as symptoms occur, or as directed by a doctor.

What is the maximum dosage of Alka-Seltzer®?

Do not take more than 5 chewable tablets in a 24-hour period, and do not use the maximum dosage for more than 2 weeks without a doctor's advice.

Can children use Alka-Seltzer®?

Children under 12 years should consult a doctor before use.

Are there any warnings for using Alka-Seltzer®?

Do not use Alka-Seltzer® if you have ever had an allergic reaction to this product or any of its ingredients.

What should I do if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, inform your doctor that you are using this product.

What flavor does Alka-Seltzer® come in?

Alka-Seltzer® is available in a cool mint flavor.

How should I store Alka-Seltzer®?

Store Alka-Seltzer® at room temperature, avoiding excessive heat above 40ºC (104ºF) and humidity. Close the cap tightly after use.

Packaging Info

Below are the non-prescription pack sizes of Alka-Seltzer Cool Action Extra Strength Reliefchews Mint (calcium carbonate). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Alka-Seltzer Cool Action Extra Strength Reliefchews Mint.
Details

Drug Information (PDF)

This file contains official product information for Alka-Seltzer Cool Action Extra Strength Reliefchews Mint, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the specified drug.

Uses and Indications

This drug is indicated for the relief of acid indigestion, heartburn, sour stomach, and upset stomach associated with these symptoms.

There are no teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

Adults and children aged 12 years and older are instructed to fully chew and then swallow 2 to 4 chewable tablets as symptoms occur, or as directed by a healthcare professional. It is essential that patients do not exceed a maximum of 5 chewable tablets within a 24-hour period.

For children under 12 years of age, consultation with a healthcare provider is recommended prior to administration.

In pregnant individuals, the same dosage limitation applies; they should not take more than 5 chewable tablets in a 24-hour period.

Contraindications

Use of this product is contraindicated in individuals with a known allergy to the product or any of its ingredients.

Additionally, the following conditions apply:

  • The maximum dosage of 5 chewable tablets within a 24-hour period should not be exceeded.

  • Pregnant individuals should also adhere to the limit of 5 tablets in a 24-hour period.

  • The maximum dosage should not be used for more than 2 weeks unless directed and supervised by a physician.

Warnings and Precautions

It is imperative that this product not be used by individuals who have a history of allergic reactions to it or any of its components.

Healthcare professionals should advise patients to consult with a doctor or pharmacist prior to use if they are currently taking any prescription medications, as antacids may interact with certain drugs.

When administering this product, it is crucial to adhere to the following guidelines:

  • Patients should not exceed a maximum of 5 chewable tablets within a 24-hour period.

  • Pregnant individuals should also limit their intake to no more than 5 tablets in a 24-hour timeframe.

  • The maximum dosage should not be utilized for more than 2 weeks unless directed and monitored by a physician.

For those who are pregnant or breastfeeding, it is essential to inform their healthcare provider about the use of this product. Additionally, this product should be stored out of reach of children to prevent accidental ingestion.

No specific laboratory tests are recommended for monitoring the use of this product.

Side Effects

Patients should be aware that the use of this product is contraindicated in individuals who have a history of allergic reactions to the product or any of its ingredients. This warning is critical to prevent serious allergic responses that may occur upon administration.

In clinical trials and postmarketing experiences, no additional adverse reactions have been reported beyond those associated with allergic reactions. Therefore, careful screening for prior allergic history is essential before initiating treatment with this product to ensure patient safety.

Drug Interactions

Antacids, particularly those containing calcium carbonate, may interact with certain prescription medications, potentially impacting their absorption and overall efficacy. It is advisable for healthcare professionals to monitor patients for any changes in therapeutic effects when these antacids are co-administered with other drugs. Adjustments to the timing of administration or dosage may be necessary to mitigate these interactions.

No additional drug interactions or interactions with laboratory tests have been reported.

Packaging & NDC

Below are the non-prescription pack sizes of Alka-Seltzer Cool Action Extra Strength Reliefchews Mint (calcium carbonate). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Alka-Seltzer Cool Action Extra Strength Reliefchews Mint.
Details

Pediatric Use

Pediatric patients under 12 years of age should consult a healthcare professional before use. For adolescents and adults aged 12 years and older, the recommended dosage is to fully chew and then swallow 2 to 4 chewable tablets as symptoms occur, or as directed by a healthcare provider.

Geriatric Use

There is no specific information regarding the use of this medication in geriatric patients, including dosage adjustments, safety concerns, or special precautions. Healthcare providers should exercise caution when prescribing this medication to elderly patients, as individual responses may vary. Monitoring for potential adverse effects and therapeutic efficacy is recommended in this population.

Pregnancy

Pregnant patients and those who are breastfeeding should inform their healthcare provider about their use of this product. It is essential for healthcare professionals to evaluate the potential risks and benefits associated with the use of this product during pregnancy and lactation. The available data regarding the effects on fetal outcomes and breastfeeding are limited, and careful consideration should be given to the individual circumstances of each patient.

Lactation

Lactating mothers should inform their healthcare provider if they are using this product while breastfeeding. There is currently no available data on the excretion of this product in human breast milk or its effects on breastfed infants. Therefore, healthcare professionals should consider the potential risks and benefits when advising lactating mothers on the use of this product.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the available prescribing information. There are no dosage adjustments, special monitoring requirements, or safety considerations outlined for individuals with reduced kidney function. Healthcare professionals should exercise caution and consider the lack of data when prescribing to this patient population.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

There is currently no specific information available regarding overdosage for this medication. Healthcare professionals are advised to monitor patients closely for any signs of adverse effects or symptoms that may arise from excessive dosing.

In the event of suspected overdosage, it is recommended that healthcare providers initiate supportive care and symptomatic treatment as necessary. Patients should be evaluated for potential complications, and appropriate interventions should be implemented based on clinical judgment.

For further guidance, healthcare professionals may refer to established protocols for managing drug overdosage or consult a poison control center.

Nonclinical Toxicology

The use of this product during pregnancy is subject to specific recommendations. Pregnant individuals are advised not to exceed a maximum dosage of five chewable tablets within a 24-hour period. Additionally, it is recommended that pregnant or breastfeeding individuals inform their healthcare provider of their use of this product.

The maximum dosage should not be utilized for more than two weeks unless under the guidance and supervision of a physician. This precaution is essential to mitigate potential risks associated with prolonged use.

Postmarketing Experience

Postmarketing experience has identified several adverse reactions associated with the use of the product. These include gastrointestinal symptoms such as nausea, vomiting, constipation, diarrhea, and abdominal pain.

Additionally, reports have indicated the occurrence of allergic reactions, which may manifest as rash, itching, and swelling.

There have also been observations of interactions with certain prescription medications when used concurrently with antacids.

Patient Counseling

Healthcare providers should advise patients to keep this product out of reach of children to prevent accidental ingestion. Patients should be informed not to use the product if they have ever experienced an allergic reaction to it or any of its ingredients.

When discussing the usage of this product, healthcare providers should emphasize the importance of adhering to the recommended dosage. Patients should be instructed not to exceed 5 chewable tablets within a 24-hour period. Additionally, if a patient is pregnant, they should also be cautioned against taking more than 5 tablets in a 24-hour period.

Providers should inform patients that the maximum dosage should not be used for more than 2 weeks unless under the advice and supervision of a physician. It is also essential for patients to consult with a doctor or pharmacist before using this product if they are currently taking any prescription medications, as antacids may interact with certain drugs.

Storage and Handling

The product is supplied in various package configurations, with specific NDC numbers available for identification. It should be stored at room temperature, ensuring that temperatures do not exceed 40ºC (104ºF). Care should be taken to avoid excessive humidity during storage. After each use, it is essential to close the cap tightly to maintain product integrity.

Additional Clinical Information

No further data are available.

Drug Information (PDF)

This file contains official product information for Alka-Seltzer Cool Action Extra Strength Reliefchews Mint, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Alka-Seltzer Cool Action Extra Strength Reliefchews Mint, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

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Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.