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Alka-Seltzer Heartburn Relief

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Active ingredient
Calcium Carbonate 750 mg
Other brand names
Drug classes
Blood Coagulation Factor, Phosphate Binder
Dosage form
Gum, Chewing
Route
Oral
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2020
Label revision date
December 4, 2025
Drug Information (PDF)
Prescribing information, PDF file
Active ingredient
Calcium Carbonate 750 mg
Other brand names
Drug classes
Blood Coagulation Factor, Phosphate Binder
Dosage form
Gum, Chewing
Route
Oral
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2020
Label revision date
December 4, 2025
Manufacturer
Bayer HealthCare LLC.
Registration number
M001
NDC root
0280-0002
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info
Packaging & NDC Codes

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

Alka-Seltzer® is an antacid that contains calcium carbonate, which helps to quickly relieve discomfort from acid indigestion, heartburn, sour stomach, and upset stomach associated with these symptoms. It is available in an extra strength gum form with a refreshing peppermint flavor, making it a convenient option for on-the-go relief.

When you chew Alka-Seltzer®, it works fast to neutralize stomach acid, providing you with the comfort you need when experiencing digestive issues. Each pack contains 16 pieces, allowing you to have effective relief readily available whenever you need it.

Uses

If you're experiencing discomfort from acid indigestion, heartburn, sour stomach, or an upset stomach related to these symptoms, this medication can help provide relief. It’s designed to ease the discomfort associated with these common digestive issues, allowing you to feel more comfortable throughout your day.

Rest assured, there are no known teratogenic effects (which means it doesn't cause birth defects) or nonteratogenic effects associated with this medication. This makes it a safer option for those concerned about potential risks.

Dosage and Administration

If you are an adult or a child aged 12 years and older, you can chew 1 to 2 pieces of the gum whenever you experience symptoms, or as your doctor advises. However, it's important not to exceed 5 pieces in a 24-hour period. If you are under 12 years old, please consult your doctor before using this product.

If you are pregnant, you should also limit yourself to no more than 5 pieces in a 24-hour period. Remember, do not swallow the gum; it is meant to be chewed. Following these guidelines will help ensure you use the medication safely and effectively.

What to Avoid

You should avoid using this product if you have ever had an allergic reaction to it or any of its ingredients. It's important to follow the recommended dosage carefully: do not use more than 5 pieces in a 24-hour period, even if you are pregnant. Additionally, do not take the maximum dosage for more than 2 weeks unless your doctor advises you to do so. Following these guidelines will help ensure your safety and well-being while using this product.

Side Effects

It's important to be aware of potential side effects when considering this medication. You should not use this product if you have ever experienced an allergic reaction to it or any of its ingredients. Allergic reactions can range from mild symptoms, like rashes, to severe reactions that may require immediate medical attention.

Always consult with your healthcare provider if you have any concerns about your health or the use of this medication.

Warnings and Precautions

You should not use this product if you have ever had an allergic reaction to it or any of its ingredients. Before using it, consult with your doctor or pharmacist, especially if you are currently taking any prescription medications, as antacids can interact with certain drugs.

When using this product, limit yourself to no more than 5 pieces in a 24-hour period. If you are pregnant, do not exceed this limit, and avoid using the maximum dosage for more than 2 weeks unless directed by a physician. If you are pregnant or breastfeeding, make sure to inform your doctor that you are using this product. Always keep it out of reach of children.

Overdose

It appears that there is no specific information available regarding overdosage for this medication. However, it's important to be aware of the general signs of an overdose, which can include symptoms like extreme drowsiness, confusion, or difficulty breathing. If you suspect that you or someone else may have taken too much of a medication, it’s crucial to seek immediate medical help.

In case of an overdose, you should contact your local emergency services or go to the nearest hospital. Having the medication packaging or information on hand can help medical professionals provide the best care. Always remember that when in doubt, it’s better to err on the side of caution and seek assistance.

Pregnancy Use

If you are pregnant or breastfeeding, it’s important to let your doctor know that you are using this product. This information helps your healthcare provider assess any potential risks and make informed decisions about your care. Always prioritize open communication with your doctor regarding any medications or treatments you are using during this time.

Lactation Use

If you are pregnant or breastfeeding, it’s important to let your doctor know that you are using this product. This information helps ensure your safety and the well-being of your baby. Always consult with your healthcare provider about any medications or products you are using while nursing, as they can provide guidance tailored to your specific situation.

Pediatric Use

If you have a child under 12 years old, it's important to consult a doctor before using this medication. For children aged 12 and older, they can chew 1 to 2 pieces when symptoms arise or as directed by a healthcare professional. However, make sure that they do not exceed a maximum of 5 pieces in a 24-hour period.

Always remember to keep this medication out of reach of children to ensure their safety.

Geriatric Use

While there is no specific information available about the use of this medication in older adults, it’s important to approach any new treatment with caution. Since older adults may have different health needs and responses to medications, you should always consult with a healthcare provider before starting any new medication. They can help determine the best approach for you or your loved one, considering any existing health conditions or medications that may interact.

Remember, your safety and well-being are the top priority, so don’t hesitate to ask questions and discuss any concerns with your doctor.

Renal Impairment

If you have kidney problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or safety considerations for your condition. This means that there are no tailored guidelines for how this medication may affect you if your kidneys are not functioning properly.

Always consult your healthcare provider for personalized advice and to ensure that any medication you take is safe and appropriate for your kidney health. They can help monitor your condition and make any necessary adjustments to your treatment plan.

Hepatic Impairment

If you have liver problems, it's important to know that the information provided does not include specific guidelines for dosage adjustments, special monitoring, or precautions related to your condition. This means that there are no tailored recommendations for how the medication may affect you differently due to your liver health.

Always consult your healthcare provider for personalized advice and to ensure that any treatment plan is safe and effective for your specific situation. They can help determine the best approach based on your liver function and overall health.

Drug Interactions

It's important to be aware that some over-the-counter medications, such as antacids containing calcium carbonate, can interact with certain prescription drugs. This interaction may affect how well those medications work in your body. Because of this, it's crucial to discuss all the medications you are taking, including any over-the-counter products, with your healthcare provider. They can help ensure that your treatments are safe and effective.

Always keep an open line of communication with your healthcare team about any changes in your medication regimen or if you have questions about how different drugs may interact. This way, you can avoid potential issues and get the best possible care.

Storage and Handling

To ensure the best performance of your product, store it at room temperature, away from humidity and excessive heat. It's important to keep it below 40ºC (104ºF) to maintain its integrity and effectiveness.

When handling the product, make sure to do so in a clean environment to avoid contamination. Always follow any specific instructions provided for safe use and disposal to ensure your safety and the product's effectiveness.

Additional Information

No further information is available.

FAQ

What is Alka-Seltzer®?

Alka-Seltzer® is a calcium carbonate-based antacid that works fast to relieve symptoms.

What symptoms does Alka-Seltzer® relieve?

It is used for the relief of acid indigestion, heartburn, sour stomach, and upset stomach associated with these symptoms.

What is the recommended dosage for adults and children over 12?

Adults and children 12 years and over should chew 1 to 2 pieces as symptoms occur or as directed by a doctor.

What is the maximum dosage of Alka-Seltzer®?

Do not use more than 5 pieces in a 24-hour period.

Can children under 12 use Alka-Seltzer®?

Children under 12 years should consult a doctor before use.

Is Alka-Seltzer® safe to use during pregnancy?

If pregnant, do not use more than 5 pieces in a 24-hour period and inform your doctor that you are using this product.

What precautions should I take when using Alka-Seltzer®?

Keep out of reach of children, and ask a doctor or pharmacist before use if you are taking a prescription drug, as antacids may interact with certain medications.

What should I do if I have an allergic reaction to Alka-Seltzer®?

Do not use Alka-Seltzer® if you have ever had an allergic reaction to this product or any of its ingredients.

How should I store Alka-Seltzer®?

Store at room temperature, avoiding humidity and excessive heat above 40ºC (104ºF).

What flavor does Alka-Seltzer® come in?

Alka-Seltzer® is available in peppermint flavor.

Packaging Info

Below are the non-prescription pack sizes of Alka-Seltzer Heartburn Relief (calcium carbonate). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Alka-Seltzer Heartburn Relief.
Details

Drug Information (PDF)

This file contains official product information for Alka-Seltzer Heartburn Relief, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the drug.

Uses and Indications

This drug is indicated for the relief of acid indigestion, heartburn, sour stomach, and upset stomach associated with these symptoms.

There are no teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

Adults and children aged 12 years and older are instructed to chew 1 to 2 pieces of the gum as symptoms occur or as directed by a healthcare professional. For children under 12 years of age, consultation with a doctor is recommended prior to use.

It is important to note that no more than 5 pieces of gum should be used within a 24-hour period. This limitation also applies to pregnant individuals. The gum should not be swallowed; it is intended for chewing only.

Contraindications

Use of this product is contraindicated in individuals with a known allergy to the product or any of its ingredients.

Additionally, the following conditions must be observed:

  • The product should not be used in excess of 5 pieces within a 24-hour period.

  • Pregnant individuals should also adhere to the limitation of no more than 5 pieces in a 24-hour period.

  • The maximum dosage should not be utilized for more than 2 weeks unless under the guidance and supervision of a physician.

Warnings and Precautions

Patients should not use this product if they have a history of allergic reactions to it or any of its ingredients.

Healthcare professionals are advised to counsel patients to consult with a doctor or pharmacist prior to use if they are currently taking any prescription medications, as antacids may interact with certain drugs.

When administering this product, it is crucial to adhere to the following precautions:

  • Patients should not exceed a maximum of 5 pieces within a 24-hour period.

  • Pregnant individuals should also limit their intake to no more than 5 pieces in a 24-hour period.

  • The maximum dosage should not be used for more than 2 weeks unless directed and supervised by a physician.

For those who are pregnant or breastfeeding, it is essential to inform their healthcare provider about the use of this product. Additionally, this product should be kept out of reach of children to prevent accidental ingestion.

No specific laboratory tests are recommended for monitoring the use of this product.

Side Effects

Patients should be aware that the use of this product is contraindicated in individuals who have a history of allergic reactions to the product or any of its ingredients. This warning is critical to prevent serious allergic responses that may occur upon administration.

In clinical trials and postmarketing experiences, no additional adverse reactions have been reported beyond those associated with allergic reactions. Therefore, healthcare providers should carefully evaluate the patient's medical history for any previous allergic responses before prescribing this product.

Drug Interactions

Antacids, particularly those containing calcium carbonate, may interact with certain prescription medications. This interaction can potentially alter the absorption and efficacy of these drugs. It is advisable for healthcare professionals to monitor patients for any changes in therapeutic effects when antacids are co-administered with other medications. Adjustments to the timing of administration or dosage may be necessary to mitigate these effects.

No additional drug interactions or laboratory test interactions have been reported.

Packaging & NDC

Below are the non-prescription pack sizes of Alka-Seltzer Heartburn Relief (calcium carbonate). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Alka-Seltzer Heartburn Relief.
Details

Pediatric Use

Pediatric patients under 12 years of age should consult a doctor before use. For adolescents and adults aged 12 years and older, the recommended dosage is to chew 1 to 2 pieces as symptoms occur or as directed by a healthcare professional. The maximum dosage should not exceed 5 pieces within a 24-hour period. It is important to keep this product out of reach of children to ensure safety.

Geriatric Use

Elderly patients may not have specific information regarding the use of this medication, including dosage adjustments, safety concerns, or special precautions. Therefore, healthcare providers should exercise caution when prescribing this medication to geriatric patients. It is advisable to monitor these patients closely for any potential adverse effects or changes in therapeutic response, given the lack of targeted data for this population.

Pregnancy

Pregnant patients and those who are breastfeeding should inform their healthcare provider about the use of this product. The potential risks associated with the use of this medication during pregnancy have not been fully established. Therefore, it is essential for women of childbearing potential to discuss their treatment options with their healthcare provider to ensure the safety of both the mother and the fetus.

Lactation

Lactating mothers should inform their healthcare provider if they are using this product while breastfeeding. There is no specific data available regarding the excretion of this product in human breast milk or its effects on breastfed infants. Therefore, healthcare professionals should consider the potential risks and benefits when advising lactating mothers on the use of this product.

Renal Impairment

Patients with renal impairment may not have specific dosage adjustments, special monitoring, or safety considerations outlined in the drug insert. Therefore, healthcare professionals should exercise caution when prescribing this medication to individuals with reduced kidney function, as the absence of detailed guidance necessitates careful clinical judgment and monitoring of these patients.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

There is currently no specific information available regarding overdosage for this medication. Healthcare professionals are advised to monitor patients closely for any signs of adverse effects or symptoms that may arise from excessive dosing.

In the event of suspected overdosage, it is recommended that healthcare providers initiate supportive care and symptomatic treatment as necessary. Patients should be evaluated for potential complications, and appropriate interventions should be implemented based on clinical judgment.

For further guidance, healthcare professionals may refer to established protocols or consult with a poison control center. It is essential to document any overdosage incidents and report them to the relevant regulatory authorities as part of ongoing safety monitoring.

Nonclinical Toxicology

If used during pregnancy, it is advised not to exceed five pieces within a 24-hour period due to potential teratogenic effects. Pregnant or breastfeeding individuals should inform their healthcare provider of the use of this product to ensure safety and appropriate monitoring. No additional relevant information regarding nonclinical toxicology or animal pharmacology and toxicology has been identified.

Postmarketing Experience

No postmarketing experience details are available in the insert text.

Patient Counseling

Healthcare providers should advise patients to keep this product out of reach of children to prevent accidental ingestion. It is important to inform patients that they should not use the product if they have ever experienced an allergic reaction to it or any of its ingredients.

When discussing the usage of this product, healthcare providers should emphasize that patients must not exceed a maximum of 5 pieces within a 24-hour period. Additionally, if a patient is pregnant, they should also adhere to the same limit of 5 pieces in a 24-hour period. Providers should caution patients against using the maximum dosage for more than 2 weeks unless directed and supervised by a physician.

Furthermore, healthcare providers should recommend that patients consult with a doctor or pharmacist before using this product if they are currently taking any prescription medications, as antacids may interact with certain prescription drugs.

Storage and Handling

The product is supplied in various package configurations, with specific NDC numbers available for identification. It is essential to store the product at room temperature, ensuring that it is kept away from humidity and excessive heat. Temperatures should not exceed 40ºC (104ºF) to maintain product integrity. Proper handling and storage conditions are crucial to ensure the efficacy and safety of the product.

Additional Clinical Information

No further data are available.

Drug Information (PDF)

This file contains official product information for Alka-Seltzer Heartburn Relief, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Alka-Seltzer Heartburn Relief, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

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Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.