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Alka-Seltzer Heartburn Reliefchews

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Active ingredient
Calcium Carbonate 750 mg
Other brand names
Drug classes
Blood Coagulation Factor, Phosphate Binder
Dosage form
Tablet, Chewable
Route
Oral
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2014
Label revision date
December 4, 2025
Drug Information (PDF)
Prescribing information, PDF file
Active ingredient
Calcium Carbonate 750 mg
Other brand names
Drug classes
Blood Coagulation Factor, Phosphate Binder
Dosage form
Tablet, Chewable
Route
Oral
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2014
Label revision date
December 4, 2025
Manufacturer
Bayer HealthCare LLC.
Registration number
M001
NDC root
0280-0221
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info (8 NDCs)
Packaging & NDC Codes (8)

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

Alka-Seltzer is an antacid that contains calcium carbonate, which helps relieve symptoms associated with excess stomach acid. If you experience acid indigestion, heartburn, a sour stomach, or an upset stomach, Alka-Seltzer can provide fast and powerful relief.

This product comes in an extra strength formula and is available in chewable tablets with an assorted fruit flavor, making it a convenient option for managing discomfort related to these common digestive issues.

Uses

If you're experiencing discomfort from acid indigestion, heartburn, sour stomach, or an upset stomach related to these symptoms, this medication can help provide relief. It’s designed to ease the discomfort associated with these common digestive issues, allowing you to feel more comfortable throughout your day.

Rest assured, there are no known teratogenic effects (which means it doesn't cause birth defects) or nonteratogenic effects associated with this medication. This makes it a safe option for those looking to alleviate their digestive discomfort.

Dosage and Administration

If you are an adult or a child aged 12 years and older, you can take 1 to 2 chewable tablets every 2 to 4 hours as needed for your symptoms. However, it's important to follow your doctor's advice if they have given you specific instructions. Make sure not to exceed 10 chewable tablets in a 24-hour period to avoid any potential side effects.

For children under 12 years old, it's best to consult a doctor before giving them this medication. They can provide guidance on the appropriate dosage and ensure it's safe for your child. Always remember to follow the recommended guidelines to use the medication safely and effectively.

What to Avoid

It's important to be aware of certain precautions when using this product. You should not use it if you have ever had an allergic reaction to it or any of its ingredients. Additionally, be mindful of the dosage: do not take more than 10 chewable tablets in a 24-hour period. If you find that you need to use the maximum dosage, do so only for a maximum of 2 weeks and under the guidance of a physician.

This product is classified as a controlled substance, which means it has the potential for abuse or misuse. It's crucial to follow these guidelines to avoid any dependence (a condition where your body becomes reliant on a substance) or other serious health issues. Always prioritize your safety and consult with a healthcare professional if you have any questions or concerns.

Side Effects

If you have ever had an allergic reaction to this product or any of its ingredients, it is important not to use it. While using this product, you may experience constipation, which is a common side effect. If you notice any unusual symptoms or have concerns, please consult your healthcare provider.

Warnings and Precautions

You should not use this product if you have ever had an allergic reaction to it or any of its ingredients. Before using it, consult with your doctor or pharmacist, especially if you are currently taking any prescription medications, as antacids can interact with certain drugs.

While using this product, remember not to exceed 10 chewable tablets in a 24-hour period, and avoid using the maximum dosage for more than 2 weeks unless directed by a physician. Be aware that constipation may occur. If you are pregnant or breastfeeding, it's important to seek advice from a healthcare professional before use. Always keep this product out of reach of children.

If you experience any severe reactions or unusual symptoms, seek emergency help immediately. Additionally, stop using the product and call your doctor if you have any concerns or if you experience persistent constipation.

Overdose

It appears that there is no specific information available regarding overdosage for this medication. However, it’s always important to be aware of the signs of an overdose, which can include unusual drowsiness, confusion, or difficulty breathing. If you suspect that you or someone else may have taken too much of a medication, it’s crucial to seek immediate medical help.

In case of an overdose, contact your local emergency services or go to the nearest hospital. Having the medication packaging or information on hand can help medical professionals provide the best care. Always remember that when in doubt, it’s better to err on the side of caution and seek assistance.

Pregnancy Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using this medication. They can provide guidance on whether it’s safe for you and your baby. Always prioritize your health and the health of your child by seeking expert advice.

Lactation Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using any medication. This ensures that you understand any potential risks and can make informed decisions about your health and the health of your baby. Always prioritize open communication with your doctor regarding your breastfeeding journey.

Pediatric Use

If you have a child under 12 years old, it's important to consult a doctor before using this medication. For children aged 12 and older, you can give them 1 to 2 chewable tablets every 2 to 4 hours as needed for symptoms, or follow your doctor's instructions. Always ensure that you are using the correct dosage for their age to keep them safe and healthy.

Geriatric Use

When it comes to using this medication in older adults, there is no specific information available about dosage adjustments, safety concerns, or special precautions. This means that if you or a loved one is an older adult, it’s important to consult with a healthcare provider before starting the medication. They can help determine the best approach based on individual health needs and any other medications being taken. Always prioritize open communication with your healthcare team to ensure safe and effective treatment.

Renal Impairment

If you have kidney problems, it's important to know that the information provided does not include specific guidelines for dosage adjustments, special monitoring, or safety considerations related to renal impairment (kidney issues). This means that there are no tailored recommendations for how your treatment may need to change based on your kidney function.

Always consult your healthcare provider for personalized advice and to ensure that your treatment is safe and effective for your specific condition. They can help determine the best approach for managing your health, especially if you have concerns about your kidneys.

Hepatic Impairment

If you have liver problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or precautions for your condition. This means that there are no detailed guidelines available regarding how the medication may affect you or how your liver health might influence the medication's effectiveness or safety.

Before starting any new medication, it's essential to discuss your liver condition with your healthcare provider. They can help determine the best approach for your treatment and ensure that you are monitored appropriately. Always keep your doctor informed about your liver health to receive the safest and most effective care.

Drug Interactions

It's important to be aware that some over-the-counter medications, such as antacids containing calcium carbonate, can interact with certain prescription drugs. This means that taking them together might affect how well your medications work.

Since there are no specific drug interactions or laboratory test interactions listed, it's still crucial to discuss all the medications and supplements you are taking with your healthcare provider. They can help ensure that your treatment is safe and effective, taking into account any potential interactions. Always keep your healthcare team informed about what you are using to avoid any unexpected issues.

Storage and Handling

To ensure the best performance of your product, store it at room temperature and keep it away from humidity. After each use, make sure to close the cap tightly to maintain its integrity and effectiveness. Proper storage and handling are essential for your safety and the product's reliability.

Additional Information

You can take this medication orally by chewing and swallowing 1-2 chewable tablets every 2 to 4 hours as needed, but do not exceed 10 tablets in a 24-hour period. If you are under 12 years old, consult a doctor before use.

Before starting this medication, it's important to ask your doctor or pharmacist if you are currently taking any prescription drugs, as antacids may interact with them. If you are pregnant or breastfeeding, consult a healthcare professional for advice before using this product.

FAQ

What is Alka-Seltzer used for?

Alka-Seltzer is used for the relief of acid indigestion, heartburn, sour stomach, and upset stomach associated with these symptoms.

How should adults and children 12 years and over take Alka-Seltzer?

Adults and children 12 years and over should chew and swallow 1-2 chewable tablets every 2 to 4 hours as symptoms occur, or as directed by a doctor.

What is the maximum dosage of Alka-Seltzer?

You should not take more than 10 chewable tablets in a 24-hour period.

Are there any contraindications for using Alka-Seltzer?

Do not use Alka-Seltzer if you have ever had an allergic reaction to this product or any of its ingredients.

What should I do if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, ask a health professional before using Alka-Seltzer.

What side effects may occur when using Alka-Seltzer?

Constipation may occur when using this product.

What should I do if I am taking other prescription drugs?

Ask a doctor or pharmacist before use if you are presently taking a prescription drug, as antacids may interact with certain medications.

How should Alka-Seltzer be stored?

Store Alka-Seltzer at room temperature, avoid humidity, and close the cap tightly after use.

What should children under 12 do before using Alka-Seltzer?

Children under 12 years should consult a doctor before use.

Packaging Info

Below are the non-prescription pack sizes of Alka-Seltzer Heartburn Reliefchews (calcium carbonate). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Alka-Seltzer Heartburn Reliefchews.
Details

Drug Information (PDF)

This file contains official product information for Alka-Seltzer Heartburn Reliefchews, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the specified drug.

Uses and Indications

This drug is indicated for the relief of acid indigestion, heartburn, sour stomach, and upset stomach associated with these symptoms.

There are no teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

Adults and children aged 12 years and older are instructed to chew and swallow 1 to 2 chewable tablets every 2 to 4 hours as symptoms occur, or as directed by a healthcare professional. For children under 12 years of age, consultation with a doctor is recommended prior to administration.

It is imperative that no more than 10 chewable tablets are taken within a 24-hour period to avoid potential overdose or adverse effects.

Contraindications

Use of this product is contraindicated in individuals with a history of allergic reactions to this product or any of its ingredients.

Additionally, the following usage restrictions apply:

  • The maximum dosage should not exceed 10 chewable tablets within a 24-hour period.

  • The maximum dosage should not be used for more than 2 weeks unless directed and supervised by a physician.

Warnings and Precautions

Patients should not use this product if they have a history of allergic reactions to it or any of its ingredients. Prior to administration, it is essential for individuals to consult with a healthcare provider or pharmacist if they are currently taking any prescription medications, as antacids may interact with certain drugs.

When utilizing this product, it is critical to adhere to the following guidelines: the maximum recommended dosage is 10 chewable tablets within a 24-hour period. Additionally, the maximum dosage should not be used for more than 2 weeks unless directed and monitored by a physician. Users should be aware that constipation may occur as a side effect.

For pregnant or breastfeeding individuals, it is advisable to seek guidance from a healthcare professional before use. Furthermore, this product should be stored out of reach of children to prevent accidental ingestion.

Side Effects

Patients should be aware that the use of this product is contraindicated in individuals who have a history of allergic reactions to the product or any of its ingredients.

In clinical experience, constipation has been reported as a common adverse reaction associated with the use of this product. Patients should be monitored for this effect, and appropriate measures should be taken to manage constipation if it occurs.

Drug Interactions

Antacids, particularly those containing calcium carbonate, may interact with certain prescription medications. It is advisable for healthcare professionals to assess the potential for interactions when prescribing medications alongside antacids. Monitoring for efficacy and side effects may be warranted, and dosage adjustments should be considered based on the specific medications involved and the clinical context.

No additional drug interactions or laboratory test interactions have been identified in the available data.

Packaging & NDC

Below are the non-prescription pack sizes of Alka-Seltzer Heartburn Reliefchews (calcium carbonate). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Alka-Seltzer Heartburn Reliefchews.
Details

Pediatric Use

Pediatric patients under 12 years of age should consult a healthcare professional before use. For adolescents aged 12 years and older, the recommended dosage is to chew and swallow 1-2 chewable tablets every 2 to 4 hours as symptoms occur, or as directed by a healthcare provider.

Geriatric Use

Elderly patients may not have specific information regarding the use of this medication, including dosage adjustments, safety concerns, or special precautions. Therefore, healthcare providers should exercise caution when prescribing this medication to geriatric patients. It is advisable to monitor these patients closely for any potential adverse effects or changes in efficacy, given the lack of targeted data for this population.

Pregnancy

Pregnant patients and those who are breastfeeding should consult a healthcare professional prior to using this medication. It is important to evaluate the potential risks and benefits associated with the use of this drug during pregnancy and lactation. Healthcare providers can offer guidance based on individual circumstances and the latest clinical data.

Lactation

Lactating mothers are advised to consult a healthcare professional prior to using this medication. There is no specific data available regarding the excretion of this medication in human breast milk or its effects on breastfed infants. Therefore, caution is recommended when administering this medication to lactating mothers.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the prescribing information regarding dosage adjustments, special monitoring, or safety considerations. Therefore, healthcare professionals should exercise caution when prescribing this medication to patients with reduced kidney function, as the absence of detailed guidance necessitates careful clinical judgment and monitoring of these patients.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in clinical trials for this medication. Consequently, there is no available information regarding dosage adjustments, special monitoring requirements, or precautions for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be warranted based on clinical judgment.

Overdosage

In the absence of specific overdosage information, it is essential for healthcare professionals to remain vigilant and prepared for potential scenarios involving overdose.

Healthcare providers should be aware that the clinical presentation of an overdose may vary depending on the substance involved and the individual patient’s characteristics. Symptoms of overdose can range from mild to severe and may include altered mental status, cardiovascular instability, respiratory distress, and gastrointestinal disturbances.

In the event of suspected overdosage, immediate medical evaluation is recommended. Healthcare professionals should assess the patient's vital signs and conduct a thorough clinical examination. Supportive care should be initiated as necessary, which may include airway management, intravenous fluids, and monitoring of vital parameters.

If specific antidotes or treatments are available for the substance involved, they should be administered according to established protocols. Consultation with a poison control center or toxicology expert may also be warranted to guide management decisions.

It is crucial to document all findings and interventions in the patient's medical record and to report any adverse events to the appropriate regulatory authorities as required.

Nonclinical Toxicology

If pregnant or breast-feeding, it is advised to consult a health professional prior to use. Constipation may occur as a non-teratogenic effect. No relevant information is available regarding nonclinical toxicology or animal pharmacology and toxicology.

Postmarketing Experience

No postmarketing experience details are provided in the insert for Alka-Seltzer Heartburn Relief Chews.

Patient Counseling

Healthcare providers should advise patients to keep this product out of reach of children to prevent accidental ingestion. Patients should be informed not to use the product if they have a history of allergic reactions to it or any of its ingredients.

When discussing the usage of this product, healthcare providers should emphasize the importance of adhering to the recommended dosage. Patients should be instructed not to exceed 10 chewable tablets within a 24-hour period and to avoid using the maximum dosage for more than 2 weeks unless directed by a physician. Providers should also inform patients that constipation may occur as a side effect of the product.

Additionally, healthcare providers should encourage patients to consult with a doctor or pharmacist before using this product if they are currently taking any prescription medications, as antacids may interact with certain drugs.

Storage and Handling

The product is supplied in a configuration that includes specific NDC numbers. It should be stored at room temperature, ensuring that it is kept away from humidity. After each use, it is essential to close the cap tightly to maintain the integrity of the product.

Additional Clinical Information

Patients should be informed that the medication is administered orally. For adults and children aged 12 years and older, the recommended dosage is to chew and swallow 1-2 chewable tablets every 2 to 4 hours as symptoms occur, or as directed by a healthcare provider. It is important not to exceed 10 chewable tablets within a 24-hour period. For children under 12 years, consultation with a doctor is advised prior to use.

Clinicians should counsel patients to consult a doctor or pharmacist before use if they are currently taking any prescription medications, as antacids may interact with certain drugs. Additionally, pregnant or breastfeeding patients should seek advice from a healthcare professional before using this medication.

Drug Information (PDF)

This file contains official product information for Alka-Seltzer Heartburn Reliefchews, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Alka-Seltzer Heartburn Reliefchews, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.