Antigrip Daytime

Description

No description information is available for the drug.

Uses and Indications

This drug is indicated for the temporary relief of symptoms associated with the common cough and cold/flu, including sore throat, headache, muscular aches, backaches, minor aches and pains, nasal congestion due to hay fever, other respiratory allergies, sinus congestion and pressure, and cough resulting from minor throat and bronchial irritation. Additionally, this drug temporarily reduces fever.

There are no teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

The recommended dosage for adults and children aged 12 years and older is one packet every 4 hours, with a maximum of 6 packets within a 24-hour period. It is imperative that the recommended dose is not exceeded.

To prepare the solution, the contents of one packet should be dissolved in 8 ounces of hot water. The mixture should be sipped while hot, and the entire drink should be consumed within 10 to 15 minutes for optimal effectiveness.

If utilizing a microwave for preparation, the contents of one packet may be added to 8 ounces of cool water. The solution should be stirred briskly before and after heating, ensuring that it is not overheated.

This product is not recommended for use in children under 12 years of age.

Contraindications

Use of this product is contraindicated in the following situations:

• Co-administration with any other drug containing acetaminophen, whether prescription or non-prescription, due to the risk of acetaminophen overdose. If there is uncertainty regarding the presence of acetaminophen in other medications, consultation with a healthcare professional is advised.

• Use for more than 7 days for pain or more than 3 days for fever is contraindicated unless directed by a healthcare provider, to prevent potential adverse effects associated with prolonged use.

• Concurrent use with prescription monoamine oxidase inhibitors (MAOIs) is contraindicated, as this may lead to serious drug interactions. Patients should verify with a healthcare professional if their current medications include an MAOI.

Warnings and Precautions

This product contains acetaminophen, which carries specific warnings and precautions that healthcare professionals should be aware of to ensure safe use.

Liver Warning Severe liver damage may occur if the maximum daily dosage of 6 packets is exceeded within a 24-hour period. Additionally, the risk of liver damage increases if this product is taken concurrently with other medications containing acetaminophen or if the patient consumes three or more alcoholic drinks daily while using this product.

Allergy Alert Acetaminophen may lead to severe skin reactions. Symptoms indicative of such reactions include skin reddening, blisters, and rash. Should any of these symptoms occur, it is imperative to discontinue use immediately and seek medical assistance.

Sore Throat Warning In cases of severe sore throat that persists for more than two days, or if it is accompanied or followed by fever, headache, rash, nausea, or vomiting, prompt consultation with a healthcare provider is advised.

General Precautions Healthcare professionals should advise patients to consult a doctor prior to use if they have any of the following conditions: liver disease, heart disease, high blood pressure, thyroid disease, diabetes, a cough accompanied by excessive phlegm, a persistent or chronic cough (as seen in smoking, asthma, or emphysema), or difficulty urinating due to an enlarged prostate gland. Additionally, patients taking the anticoagulant warfarin should seek guidance from a doctor or pharmacist before using this product.

Emergency Medical Help In the event of an accidental overdose, it is crucial to seek immediate medical help or contact a Poison Control Center. Prompt medical attention is essential for both adults and children, even if no signs or symptoms are initially apparent.

Discontinuation and Consultation Patients should be instructed to stop taking this product and consult a healthcare provider if any of the following occur: symptoms do not improve, new symptoms arise, pain or fever persists or worsens, redness or swelling is observed, or if they experience nervousness, dizziness, or sleeplessness. Furthermore, a persistent cough or symptoms lasting more than seven days, worsening symptoms, or those accompanied by fever, rash, or persistent headache may indicate a serious condition and warrant immediate medical evaluation.

Side Effects

Severe liver damage may occur in patients who exceed the maximum daily dosage of six packets within a 24-hour period, take the product in conjunction with other medications containing acetaminophen, or consume three or more alcoholic drinks daily while using this product.

Patients should be aware of the potential for severe skin reactions associated with acetaminophen, which may manifest as skin reddening, blisters, or rash. In the event of a skin reaction, it is imperative to discontinue use and seek medical assistance immediately.

In cases of severe sore throat that persists for more than two days or is accompanied by fever, headache, rash, nausea, or vomiting, patients are advised to consult a healthcare professional promptly.

Patients should also discontinue use and consult a doctor if symptoms do not improve, new symptoms arise, pain or fever persists or worsens, redness or swelling occurs, or if they experience nervousness, dizziness, or sleeplessness. Additionally, a persistent cough or symptoms lasting more than seven days, worsening, recurring, or accompanied by fever, rash, or persistent headache may indicate a serious condition and warrant medical evaluation.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there is no information available regarding interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Antigrip Daytime (acetaminophen, dextromethorphan hbr, phenylephrine hci). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Pediatric Use

Pediatric patients under 12 years of age should not use this medication. For adults and children aged 12 years and older, the recommended dosage is one packet every 4 hours.

It is essential to keep this medication out of reach of children. In the event of an accidental overdose, immediate medical assistance should be sought, or contact a Poison Control Center. Prompt medical attention is critical for both adults and children, even if no signs or symptoms are apparent.

Geriatric Use

Elderly patients may not have specific information regarding the use of this medication, including dosage adjustments, safety concerns, or special precautions. Therefore, healthcare providers should exercise caution when prescribing this medication to geriatric patients. It is advisable to monitor these patients closely for any adverse effects or changes in therapeutic response, given the lack of targeted data for this population.

Pregnancy

Pregnant patients and those who are breastfeeding should consult a healthcare professional prior to using this medication. The potential risks and benefits must be carefully considered in these populations to ensure the safety of both the mother and the fetus or infant.

Lactation

Lactating mothers are advised to consult a health professional prior to using this medication. There is currently no available data on the excretion of this drug in human breast milk or its effects on breastfed infants. Therefore, caution is recommended when administering this medication to lactating individuals.

Renal Impairment

Patients with renal impairment should consult a healthcare professional prior to use, particularly if they experience difficulties with urination due to an enlarged prostate gland. It is essential to assess renal function and consider potential dosing adjustments or monitoring requirements based on the degree of impairment.

Hepatic Impairment

Patients with hepatic impairment should consult a healthcare professional prior to using this product. It is important to note that this product contains acetaminophen, which can pose a risk of severe liver damage. Patients with compromised liver function must be particularly cautious, as taking more than 6 packets in a 24-hour period is the maximum daily amount and can lead to significant adverse effects. Additionally, concurrent use of other medications containing acetaminophen or the consumption of 3 or more alcoholic drinks daily while using this product may further increase the risk of liver damage. Monitoring of liver function is advised in patients with existing liver disease to prevent potential complications.

Overdosage

In the event of an accidental overdose, it is imperative to seek immediate medical assistance or contact a Poison Control Center without delay. Prompt medical intervention is crucial for both adults and children, regardless of whether any signs or symptoms are apparent.

Healthcare professionals are advised to remain vigilant, as the absence of symptoms does not preclude the possibility of serious complications. Early recognition and management of an overdose can significantly influence patient outcomes. Therefore, it is essential to ensure that patients and caregivers are aware of the importance of timely medical evaluation in such situations.

Nonclinical Toxicology

If pregnant or breastfeeding, it is advised to consult a health professional prior to use. No specific non-teratogenic effects have been identified in the available data. Additionally, there are no detailed findings regarding nonclinical toxicology or animal pharmacology and toxicology provided in the current information.

Postmarketing Experience

Postmarketing experience has identified the following adverse reactions: severe skin reactions, which may manifest as skin reddening, blisters, and rash. In the event of a skin reaction, it is advised to discontinue use and seek medical assistance promptly.

Patient Counseling

Healthcare providers should advise patients to seek immediate medical assistance or contact a Poison Control Center in the event of an accidental overdose, as prompt medical attention is crucial for both adults and children, even if no signs or symptoms are initially apparent.

Patients should be informed not to use this medication in conjunction with any other drug containing acetaminophen, whether prescription or non-prescription. If patients are uncertain about the presence of acetaminophen in their medications, they should be encouraged to consult with a doctor or pharmacist.

It is important to instruct patients not to use this medication for more than 7 days for pain relief or more than 3 days for fever, unless otherwise directed by a healthcare professional. Patients should also be advised to discontinue use and consult a doctor if their symptoms do not improve, if new symptoms arise, or if pain or fever persists or worsens. Additionally, patients should be informed to stop use and seek medical advice if they experience redness or swelling, nervousness, dizziness, or sleeplessness.

Patients should be cautioned to stop use and consult a doctor if they have a persistent cough or if symptoms last longer than 7 days, worsen, recur, or are accompanied by a fever, rash, or persistent headache, as these may indicate a serious condition.

Before initiating treatment, healthcare providers should recommend that patients consult a doctor if they have any of the following conditions: liver disease, heart disease, high blood pressure, thyroid disease, diabetes, a cough accompanied by excessive phlegm, a persistent or chronic cough associated with smoking, asthma, or emphysema, or difficulty urinating due to an enlarged prostate gland. Furthermore, patients taking the blood-thinning medication warfarin should be advised to consult a doctor or pharmacist prior to use.

Storage and Handling

The product is supplied in a tamper-evident packaging format. It is essential to inspect the carton and packets prior to use; do not utilize the product if the packaging is torn or punctured.

For optimal storage, the product should be maintained at room temperature, specifically within the range of 68-77°F (20-25°C). It is crucial to avoid exposure to excessive heat and moisture to ensure the integrity and efficacy of the product.

Additional Clinical Information

Patients should administer the medication orally, taking one packet every four hours, with a maximum of six packets in a 24-hour period. The contents of each packet should be dissolved in 8 oz. of hot water and consumed within 10-15 minutes. If using a microwave, the packet's contents can be added to 8 oz. of cool water, stirred briskly before and after heating, ensuring not to overheat.

Clinicians should advise patients who are pregnant or breastfeeding to consult a health professional prior to use. In the event of an accidental overdose, it is crucial to seek medical assistance or contact a Poison Control Center immediately, as prompt attention is essential for both adults and children, regardless of the presence of symptoms.

Drug Information (PDF)

This file contains official product information for Antigrip Daytime, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)