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Ap-24

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This product has been discontinued

Active ingredient
Sodium Fluoride 0.2 mg/1 mL
Other brand names
Dosage form
Mouthwash
Route
Oral
Prescription status
OTC (over the counter)
Marketed in the U.S.
Since 2017
Label revision date
January 7, 2025
Active ingredient
Sodium Fluoride 0.2 mg/1 mL
Other brand names
Dosage form
Mouthwash
Route
Oral
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Marketed in the U.S.
Since 2017
Label revision date
January 7, 2025
Manufacturer
NSE Products, Inc
Registration number
M021
NDC root
62839-1152

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

AP24® is an anti-plaque fluoride mouthwash designed to help you maintain good oral health. It aids in the prevention of dental cavities, making it a useful addition to your daily dental care routine. Manufactured by NU SKIN®, this mouthwash comes in a 500 ml (16.9 Fl. Oz.) bottle, providing you with a convenient way to support your dental hygiene.

Uses

You can use this product to help prevent dental cavities. By incorporating it into your oral care routine, you can support your dental health and reduce the risk of developing cavities. Regular use is an important step in maintaining a healthy smile.

Dosage and Administration

After brushing your teeth with toothpaste, you can use this mouth rinse once a day. For adults and children aged 6 years and older, take 10 milliliters of the rinse and swish it vigorously between your teeth for 1 minute before spitting it out. It's important not to swallow the rinse.

After using the mouth rinse, avoid eating or drinking for 30 minutes to allow the product to work effectively. If you're helping children under 12, make sure to teach them good rinsing habits to prevent swallowing the rinse, and supervise them until they can rinse on their own. For children under 6 years old, it's best to consult a dentist or doctor before use.

What to Avoid

It's important to ensure your safety when using this product. You should not use it if the safety seal is broken, as this could indicate that the product is compromised.

Currently, there are no specific contraindications, controlled substance classifications, or concerns regarding abuse, misuse, or dependence associated with this product. Always prioritize your health and safety by following these guidelines.

Side Effects

It's important to keep this product out of the reach of children. If more than the recommended amount is accidentally swallowed, seek medical help or contact a Poison Control Center immediately. Additionally, do not use the product if the safety seal is broken, as this may indicate that the product is not safe to use.

Warnings and Precautions

It's important to keep this product out of the reach of children. If a child accidentally swallows more than what is used for rinsing, seek medical help or contact a Poison Control Center immediately. Additionally, do not use the product if the safety seal is broken, as this could indicate that the product is not safe to use.

There are no specific general precautions or laboratory tests required for this product. However, always prioritize safety and follow the instructions provided. If you have any concerns or experience unusual symptoms, it's best to consult your doctor.

Overdose

If you accidentally swallow more of this product than intended for rinsing, it’s important to seek medical help immediately or contact a Poison Control Center. Acting quickly can help ensure your safety.

Signs of an overdose may not be obvious, but if you experience any unusual symptoms after swallowing too much, don’t hesitate to reach out for assistance. Remember, it’s always better to be cautious when it comes to your health.

Pregnancy Use

There is currently no specific information available regarding the use of AP-24 sodium fluoride mouthwash during pregnancy. This means that safety concerns, dosage adjustments, or any special precautions for pregnant individuals have not been addressed in the drug insert.

If you are pregnant or planning to become pregnant, it is always best to consult with your healthcare provider before using any new products, including mouthwash, to ensure they are safe for you and your baby.

Lactation Use

If you are breastfeeding, you can feel reassured that there are no specific warnings or recommendations regarding the use of this product while nursing. Additionally, there is no information available about whether this product is excreted in breast milk or any potential risks it may pose to your infant. Always consult with your healthcare provider if you have any concerns or questions about medications while breastfeeding.

Pediatric Use

It's important to keep this product out of reach of children. If a child accidentally swallows more than the amount used for rinsing, seek medical help or contact a Poison Control Center immediately. For children aged 6 years and older, you can use this product once a day after brushing their teeth.

For children under 12, it's essential to teach them proper rinsing habits to help prevent swallowing. Always supervise younger children until they can use the product safely on their own. If your child is under 6 years old, please consult a dentist or doctor before use.

Geriatric Use

When it comes to using this medication in older adults, there is no specific information available about dosage adjustments, safety concerns, or special precautions. This means that if you or a loved one is an older adult considering this medication, it’s important to consult with a healthcare provider. They can help determine the best approach based on individual health needs and any other medications being taken. Always prioritize open communication with your healthcare team to ensure safe and effective treatment.

Renal Impairment

If you have kidney problems, it's important to know that the information provided does not include specific guidelines for dosage adjustments, special monitoring, or safety considerations related to renal impairment (kidney issues). This means that there are no tailored recommendations for how your treatment may need to change based on your kidney function.

Always consult your healthcare provider for personalized advice and to ensure that your treatment is safe and effective for your specific condition. They can help determine the best approach for managing your health, especially if you have concerns about your kidneys.

Hepatic Impairment

If you have liver problems, it's important to know that there are no specific guidelines or dosage adjustments mentioned for your condition in the available information. This means that the standard recommendations apply, but you should always consult your healthcare provider for personalized advice. They can help determine the best approach for your treatment and monitor your liver function as needed.

Make sure to keep your doctor informed about your liver health, as they may need to conduct regular tests to ensure your safety while using any medication. Your well-being is a priority, and your healthcare team is there to support you.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications you are taking, even if there are no specific drug interactions or laboratory test interactions noted for your treatment. This ensures that your healthcare team can monitor your health effectively and make informed decisions about your care.

Always feel free to ask questions and share any other medications or supplements you might be using. This helps to create a comprehensive picture of your health and ensures your safety while receiving treatment.

Storage and Handling

It's important to handle and store your product safely to ensure its effectiveness. First, always check that the safety seal is intact before use; do not use it if the seal is broken. Store the product at room temperature, away from direct sunlight and moisture. To keep it safe, make sure to keep it out of the reach of children. Once opened, please remember to discard the product to maintain safety and hygiene.

By following these simple guidelines, you can help ensure that the product remains safe and effective for your use.

Additional Information

You should take this medication orally, using it once a day after brushing your teeth. For adults and children aged 6 years and older, vigorously swish 10 milliliters of the rinse between your teeth for 1 minute, then spit it out. Remember not to swallow the rinse, and avoid eating or drinking for 30 minutes after using it.

If you have children under 12, make sure to teach them proper rinsing habits to prevent swallowing the rinse. Supervise younger children until they can use it safely on their own. For children under 6 years old, consult a dentist or doctor before use.

FAQ

What is AP24®?

AP24® is an anti-plaque fluoride mouthwash that aids in the prevention of dental cavities.

How should I use AP24®?

Use AP24® once a day after brushing your teeth. Vigorously swish 10 milliliters of the rinse between your teeth for 1 minute and then spit it out.

What should I avoid after using AP24®?

Do not eat or drink for 30 minutes after rinsing with AP24®.

Is AP24® safe for children?

Children under 12 years should be instructed in good rinsing habits, and those under 6 years should consult a dentist or doctor.

What should I do if I accidentally swallow AP24®?

If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away.

Are there any contraindications for AP24®?

There are no contraindications listed for AP24®.

What precautions should I take when using AP24®?

Keep AP24® out of the reach of children and do not use it if the safety seal is broken.

Is there any information about using AP24® during pregnancy or lactation?

There is no specific information regarding the use of AP24® during pregnancy or lactation.

How should I store AP24®?

Store AP24® at room temperature and discard it after opening.

Packaging Info

Below are the non-prescription pack sizes of Ap-24 (sodium fluoride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Ap-24.
Details

Drug Information (PDF)

This file contains official product information for Ap-24, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

AP24® is an anti-plaque fluoride mouthwash developed by NU SKIN®. This product is available in a 500 ml (16.9 Fl. Oz.) dosage form.

Uses and Indications

This drug is indicated for the prevention of dental cavities. It is intended for use in individuals at risk of developing dental caries.

Dosage and Administration

Adults and children aged 6 years and older are instructed to use the rinse once daily, following the brushing of teeth with toothpaste. The recommended method of administration involves vigorously swishing 10 milliliters of the rinse between the teeth for a duration of 1 minute, after which the solution should be expectorated. It is imperative that the rinse is not swallowed.

Patients should refrain from eating or drinking for 30 minutes following the rinsing procedure to ensure optimal efficacy. For children under 12 years of age, it is essential to instruct them in proper rinsing techniques to minimize the risk of swallowing the rinse. Supervision may be required until the child demonstrates the ability to use the rinse independently.

For children under 6 years of age, consultation with a dentist or physician is recommended prior to use.

Contraindications

Use is contraindicated if the safety seal is broken, as this may compromise the integrity and safety of the product.

Warnings and Precautions

It is imperative to keep this product out of the reach of children. In the event that more than the recommended amount for rinsing is accidentally ingested, immediate medical assistance should be sought, or contact a Poison Control Center without delay.

The product should not be used if the safety seal is broken, as this may compromise its integrity and safety.

No specific general precautions or laboratory tests have been provided; however, healthcare professionals should remain vigilant regarding the proper use and handling of this product to ensure patient safety.

Side Effects

Patients should be advised to keep the product out of the reach of children. In the event that more than the recommended amount for rinsing is accidentally swallowed, it is imperative to seek medical assistance or contact a Poison Control Center immediately.

Additionally, the product should not be used if the safety seal is broken, as this may indicate potential contamination or compromised integrity.

Drug Interactions

There are no specific drug interactions or laboratory test interactions identified in the available data. Therefore, no recommendations for dosage adjustments or monitoring are necessary at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Ap-24 (sodium fluoride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Ap-24.
Details

Pediatric Use

Pediatric patients should be instructed to keep the product out of reach of children. In the event that more than the recommended amount for rinsing is accidentally swallowed, medical assistance or contact with a Poison Control Center is advised immediately.

For children aged 6 years and older, the product is indicated for use once daily after brushing teeth with toothpaste. It is important to instruct children under 12 years of age in proper rinsing techniques to minimize the risk of swallowing. Supervision is recommended for children until they are capable of using the product without assistance.

For children under 6 years of age, consultation with a dentist or doctor is recommended prior to use.

Geriatric Use

There is no specific information regarding the use of this medication in geriatric patients, including dosage adjustments, safety concerns, or special precautions. Healthcare providers should exercise caution when prescribing this medication to elderly patients, as individual responses may vary. Monitoring for potential adverse effects and therapeutic efficacy is recommended in this population.

Pregnancy

There is no specific information regarding the use of AP-24 sodium fluoride mouthwash during pregnancy. The drug insert does not provide safety concerns, dosage modifications, or special precautions for pregnant patients. Therefore, healthcare professionals should exercise caution when recommending this product to women of childbearing potential and consider the lack of data when assessing the potential risks and benefits for pregnant patients.

Lactation

There are no specific warnings or recommendations regarding the use of this product by lactating mothers. Additionally, there is no information available about the potential for excretion in breast milk or any associated risks to breastfed infants.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the available prescribing information. There are no dosage adjustments, special monitoring requirements, or safety considerations outlined for individuals with reduced kidney function. Healthcare professionals should exercise caution and consider the lack of data when prescribing to this patient population.

Hepatic Impairment

There is no information available regarding the use of this medication in patients with hepatic impairment. Consequently, there are no dosage adjustments, special monitoring requirements, or precautions specified for individuals with compromised liver function. Healthcare professionals should exercise clinical judgment when considering the use of this medication in patients with liver problems, as the absence of data does not preclude the need for careful evaluation and monitoring based on individual patient circumstances.

Overdosage

In the event of an overdosage, immediate medical assistance is crucial. If an individual accidentally swallows more than the amount intended for rinsing, it is imperative to seek medical help or contact a Poison Control Center without delay.

Healthcare professionals should be aware that prompt intervention can significantly mitigate potential adverse effects associated with overdosage. Monitoring for symptoms and providing appropriate management based on clinical presentation is essential.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data in these areas limits the understanding of the compound's potential effects in nonclinical settings.

Postmarketing Experience

No postmarketing experience details are available in the provided text.

Patient Counseling

Healthcare providers should advise patients to keep the medication out of the reach of children to prevent accidental ingestion. It is important to emphasize that if more than the recommended amount used for rinsing is accidentally swallowed, patients should seek medical help or contact a Poison Control Center immediately. This guidance is crucial for ensuring patient safety and minimizing potential risks associated with accidental ingestion.

Storage and Handling

The product is supplied with a safety seal; it should not be used if this seal is broken. It is essential to store the product at room temperature. Additionally, it must be kept out of the reach of children. Once opened, the product should be discarded to ensure safety and efficacy.

Additional Clinical Information

The product is administered orally, with a recommended dosage of once daily for adults and children aged 6 years and older, following tooth brushing. Patients should vigorously swish 10 milliliters of the rinse between their teeth for 1 minute before spitting it out. It is important that patients do not swallow the rinse and refrain from eating or drinking for 30 minutes post-rinsing.

Clinicians should counsel patients, particularly parents of children under 12 years, on the importance of good rinsing habits to minimize the risk of swallowing. Supervision is advised for younger children until they can use the rinse independently. For children under 6 years of age, consultation with a dentist or doctor is recommended.

Drug Information (PDF)

This file contains official product information for Ap-24, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Ap-24, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

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Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.