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Anal-Ese

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Active ingredient
Benzocaine 7.5 g/100 mL
Other brand names
Drug class
Standardized Chemical Allergen
Dosage form
Cream
Route
Topical
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2023
Label revision date
November 10, 2025
Drug Information (PDF)
Prescribing information, PDF file
Active ingredient
Benzocaine 7.5 g/100 mL
Other brand names
Drug class
Standardized Chemical Allergen
Dosage form
Cream
Route
Topical
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2023
Label revision date
November 10, 2025
Manufacturer
Novelties by Nasswalk, Inc.
Registration number
M017
NDC root
83608-106
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info (2 NDCs)
Packaging & NDC Codes (2)

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

ANAL-ESE is a desensitizing lubricant designed to make anal penetration less painful. It is particularly useful for individuals seeking a more comfortable experience. This product is cherry-flavored and is available in various sizes, including 1.5 oz tubes and cartons, as well as smaller 0.5 oz options.

Distributed by Novelties by Nasswalk Inc., ANAL-ESE aims to enhance comfort during intimate moments, providing a supportive solution for those who may need it.

Uses

If you're looking for a way to make anal penetration more comfortable, this product serves as a desensitizing lubricant. It can help reduce discomfort during this activity, allowing for a more enjoyable experience.

Rest assured, there are no concerns regarding teratogenic effects (which refer to substances that can cause birth defects) or nonteratogenic effects associated with this lubricant. This means it is considered safe in those aspects.

Dosage and Administration

To use ANAL-ESE effectively, start by applying a small amount of the product to the rectal area before any penetration. This helps to numb the area for a more comfortable experience. After applying, it's important to wait a few minutes to allow the desensitization (numbing) effect to take place before proceeding with penetration.

As you become more familiar with the product, you'll find the right amount to use and the optimal waiting time that works best for you. Each person's experience may vary, so take your time to discover what feels most comfortable.

What to Avoid

You can feel reassured that there are no specific contraindications, controlled substance classifications, or concerns regarding abuse, misuse, or dependence associated with this medication. This means that, based on the available information, there are no particular situations or conditions under which you should avoid using it. Always consult with your healthcare provider if you have any questions or concerns about your treatment.

Side Effects

It's important to use this product only on the skin and avoid contact with your eyes. Prolonged use is not recommended. If you experience discomfort, or if you notice any rash or irritation while using the product, you should stop using it immediately and consult your doctor.

Warnings and Precautions

This product is intended for external use only, so please avoid applying it near your eyes. It’s important not to use it for an extended period. If you experience any discomfort related to the condition you are treating, or if you develop a rash or irritation, stop using the product immediately and consult your doctor.

Always prioritize your health and safety by following these guidelines closely. If you have any concerns or questions about using this product, don’t hesitate to reach out to your healthcare provider for advice.

Overdose

It appears that there is no specific information available regarding overdosage for this medication. However, it’s always important to be aware of the signs of an overdose, which can include unusual drowsiness, confusion, or difficulty breathing. If you suspect that you or someone else may have taken too much of a medication, it’s crucial to seek immediate medical help.

In case of an overdose, contact your local emergency services or go to the nearest hospital. Having the medication packaging or information on hand can help medical professionals provide the best care. Always remember that when in doubt, it’s better to err on the side of caution and seek assistance.

Pregnancy Use

There is currently no information available about the use of ANAL-ESE desensitizer cream during pregnancy. This means that safety concerns, dosage adjustments, or any special precautions for pregnant individuals have not been addressed in the drug insert.

If you are pregnant or planning to become pregnant, it is important to consult with your healthcare provider before using this product to ensure it is safe for you and your baby.

Lactation Use

If you are breastfeeding or planning to breastfeed, it's important to know that there is no specific information available regarding the use of this medication during lactation (the period when you are nursing). This means that the effects on breast milk and your nursing infant are not clearly defined.

Since there are no guidelines or precautions provided, it's a good idea to consult with your healthcare provider to discuss any concerns you may have about using this medication while breastfeeding. They can help you weigh the benefits and risks based on your individual situation.

Pediatric Use

It's important to keep this medication out of reach of children. This precaution helps prevent accidental ingestion, which can be dangerous. Always store it in a safe place where children cannot access it, ensuring their safety at all times. If you have any concerns or questions about the medication, don't hesitate to reach out to your healthcare provider for guidance.

Geriatric Use

While there is no specific information about the use of ANAL-ESE desensitizer cream in older adults, it’s important to approach any new medication with caution. Since the drug insert does not mention dosage adjustments or safety concerns for elderly patients, you should consult with a healthcare professional before using this cream. They can provide personalized advice based on your health status and any other medications you may be taking. Always prioritize safety and ensure that any treatment is appropriate for your individual needs.

Renal Impairment

If you have kidney problems, it's important to know that the information provided does not include specific guidelines for dosage adjustments, special monitoring, or safety considerations related to renal impairment (kidney issues). This means that there are no tailored recommendations for how your treatment may need to change based on your kidney function.

Always consult your healthcare provider for personalized advice and to ensure that your treatment is safe and effective, especially if you have concerns about your kidney health. They can provide guidance based on your individual situation.

Hepatic Impairment

If you have liver problems, it's important to know that the information provided does not include specific guidelines for dosage adjustments, special monitoring, or precautions related to your condition. This means that there are no tailored recommendations for how the medication may affect you differently due to your liver health.

It's always best to discuss your liver condition with your healthcare provider before starting any new medication. They can provide personalized advice and ensure that your treatment is safe and effective for you.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you. Always share your complete list of medications and any recent lab tests to avoid any potential issues. Your health and safety should always come first.

Storage and Handling

To ensure the best performance and safety of your product, store it at room temperature. It's important to keep the container tightly closed when not in use to prevent contamination and maintain its effectiveness. Additionally, protect the product from excessive heat, as high temperatures can compromise its quality. Once opened, please remember to discard the product to avoid any potential risks associated with prolonged exposure to air or contaminants. Following these guidelines will help you use the product safely and effectively.

Additional Information

This medication is intended for external use only and should be applied topically. Avoid using it near your eyes and do not use it for an extended period. If you experience discomfort, or if a rash or irritation develops, stop using the product and consult your physician. It is specifically used for the prevention of premature ejaculation.

FAQ

What is ANAL-ESE?

ANAL-ESE is a desensitizing lubricant designed for less painful anal penetration.

What flavors does ANAL-ESE come in?

ANAL-ESE is cherry flavored.

How should I use ANAL-ESE?

Apply a small amount to the rectal area prior to penetration and wait a few minutes for desensitization.

Are there any warnings for using ANAL-ESE?

Yes, it is for external use only, should not be used near the eyes, and is not for prolonged use. Discontinue use if discomfort, rash, or irritation occurs.

Is there any information about using ANAL-ESE during pregnancy or breastfeeding?

No specific information regarding use during pregnancy or breastfeeding is provided.

How should I store ANAL-ESE?

Store at room temperature, keep tightly closed when not in use, and protect from excessive heat.

What should I do if I experience discomfort while using ANAL-ESE?

If you experience discomfort, rash, or irritation, discontinue use and consult a physician.

Is there any information on drug interactions with ANAL-ESE?

No drug interactions information is provided.

What is the net weight of ANAL-ESE?

ANAL-ESE has a net weight of 1.5 oz.

Who distributes ANAL-ESE?

ANAL-ESE is distributed by Novelties by Nasswalk Inc, located in North Bergen, NJ.

Packaging Info

Below are the non-prescription pack sizes of Anal-Ese (desensitizer). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Anal-Ese.
Details

Drug Information (PDF)

This file contains official product information for Anal-Ese, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the specified drug.

Uses and Indications

This drug is indicated as a desensitizing lubricant for use in situations where less painful anal penetration is desired.

There are no teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

Healthcare professionals are advised to apply a small amount of ANAL-ESE to the rectal area prior to penetration. It is important to allow a few minutes for desensitization to occur before attempting penetration. The appropriate amount of product and the waiting time may be determined after several uses, as individual responses may vary.

Contraindications

There are no contraindications associated with the use of this product. It is not classified as a controlled substance, and there are no known risks of abuse, misuse, or dependence. Therefore, no specific instructions regarding avoidance or non-use are necessary.

Warnings and Precautions

For external use only. It is imperative that the preparation is not applied near the eyes to prevent potential irritation or injury. Prolonged use of this product is not recommended, as it may lead to adverse effects.

In the event that the condition for which the preparation is being used causes discomfort, or if any rash or irritation develops, the user should discontinue use immediately and seek consultation from a physician. Monitoring for these adverse reactions is essential to ensure patient safety and effective management of the condition being treated.

Side Effects

Patients should be aware that the product is intended for external use only and should not be applied near the eyes. Prolonged use of the product is not recommended. In clinical practice, if the condition for which the preparation is used causes discomfort, or if any rash or irritation develops, it is advised to discontinue use immediately and consult a physician.

These warnings are critical to ensure the safety and well-being of patients using the product. Adherence to these guidelines is essential to minimize the risk of adverse reactions.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there is no information available regarding interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Anal-Ese (desensitizer). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Anal-Ese.
Details

Pediatric Use

Pediatric patients should be advised to keep this medication out of reach of children. Safety and efficacy have not been established in pediatric populations, and caution is advised when administering this medication to younger individuals.

Geriatric Use

There is no specific information regarding the use of ANAL-ESE desensitizer cream in geriatric patients, including dosage adjustments, safety concerns, or special precautions. Healthcare providers should exercise caution when prescribing this medication to elderly patients, as the absence of data necessitates careful consideration of individual patient factors and potential risks. Monitoring for any adverse effects is advisable in this population, given the lack of established guidelines for geriatric use.

Pregnancy

There is no information available regarding the use of ANAL-ESE desensitizer cream during pregnancy, including safety concerns, dosage modifications, or any special precautions. Healthcare professionals should exercise caution when considering the use of this product in pregnant patients due to the lack of data on potential risks or fetal impacts. Women of childbearing potential should be informed of the absence of information and advised to consult their healthcare provider for personalized recommendations.

Lactation

There is no specific information available regarding the use of this medication in nursing mothers or its effects on lactation. Additionally, no data are provided concerning the excretion of this medication in breast milk or its potential effects on breastfed infants. Healthcare professionals should consider the lack of information when advising lactating mothers about the use of this medication.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the available prescribing information. There are no dosage adjustments, special monitoring requirements, or safety considerations outlined for individuals with reduced kidney function. Healthcare professionals should exercise caution and consider the lack of data when prescribing to this patient population.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

In the absence of specific overdosage information, it is essential for healthcare professionals to remain vigilant regarding the potential for overdose with this medication. In cases where an overdose is suspected, immediate medical attention should be sought.

Healthcare providers are advised to monitor patients closely for any signs or symptoms that may indicate an overdose. These may include, but are not limited to, altered mental status, cardiovascular instability, or gastrointestinal disturbances.

Management of an overdose should be tailored to the individual patient and may involve supportive care, symptomatic treatment, and, if applicable, the use of specific antidotes. It is crucial to consult local poison control guidelines and the product's prescribing information for detailed management protocols.

In summary, while specific overdosage data is not available, healthcare professionals should exercise caution and be prepared to act swiftly in the event of an overdose scenario.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the use of the compound in these contexts.

Postmarketing Experience

No postmarketing experience details are available in the insert text.

Patient Counseling

Healthcare providers should advise patients to keep the medication out of reach of children to prevent accidental ingestion or misuse. It is important to emphasize the necessity of proper storage to ensure the safety of young children.

Storage and Handling

The product is supplied in a configuration that ensures optimal usability. It should be stored at room temperature, away from excessive heat sources. To maintain product integrity, it is essential to keep the container tightly closed when not in use. Additionally, the product must be discarded after opening to ensure safety and efficacy.

Additional Clinical Information

The product is administered topically and is intended for external use only. Clinicians should advise patients not to apply the product near the eyes and to avoid prolonged use. If patients experience discomfort, rash, or irritation while using the preparation, they should discontinue use and consult a physician. The product is indicated for the prevention of premature ejaculation.

Drug Information (PDF)

This file contains official product information for Anal-Ese, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Anal-Ese, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.