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Anal-Ese

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Active ingredient
Benzocaine 7.5 g/100 mL
Other brand names
Drug class
Standardized Chemical Allergen
Dosage form
Cream
Route
Topical
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2023
Label revision date
November 10, 2025
Drug Information (PDF)
Prescribing information, PDF file
Active ingredient
Benzocaine 7.5 g/100 mL
Other brand names
Drug class
Standardized Chemical Allergen
Dosage form
Cream
Route
Topical
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2023
Label revision date
November 10, 2025
Manufacturer
Novelties by Nasswalk, Inc.
Registration number
M017
NDC root
83608-107
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info (2 NDCs)
Packaging & NDC Codes (2)

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

ANAL-ESE is a desensitizing lubricant designed to make anal penetration less painful. It is particularly useful for individuals seeking a more comfortable experience. This product is available in a strawberry flavor and comes in two sizes: 1.5 oz and 0.5 oz.

Marketed as "THE Original," ANAL-ESE is distributed by Novelties by Nasswalk Inc. If you're looking for a product to enhance comfort during intimate moments, ANAL-ESE may be a suitable option for you.

Uses

If you're looking for a way to make anal penetration more comfortable, this product serves as a desensitizing lubricant. It can help reduce discomfort, allowing for a more enjoyable experience.

Rest assured, there are no known teratogenic effects (which means it doesn't cause birth defects) associated with this lubricant, making it a safer choice for those concerned about such risks.

Dosage and Administration

To use ANAL-ESE effectively, start by applying a small amount of the product to the rectal area before any penetration. This helps to numb the area for a more comfortable experience. After applying, it's important to wait a few minutes to allow the desensitization (numbing) effect to take place before proceeding.

As you become more familiar with the product, you'll find the right amount to use and the optimal waiting time that works best for you. Each person's experience may vary, so take your time to discover what feels most comfortable.

What to Avoid

You can feel reassured that there are no specific contraindications, controlled substance classifications, or risks of abuse or misuse associated with this medication. Additionally, there are no concerns regarding dependence (a condition where the body becomes reliant on a substance) or any explicit instructions advising against its use. Always consult with your healthcare provider if you have any questions or concerns about your treatment.

Side Effects

It's important to be aware of some key warnings when using this product. It is meant for external use only, so avoid applying it near your eyes. Prolonged use is not recommended. If you experience discomfort, or if you notice any rash or irritation while using the product, you should stop using it immediately and consult a physician for further advice.

Warnings and Precautions

This product is intended for external use only, so please avoid applying it near your eyes. It’s important not to use it for an extended period. If you experience discomfort from the condition you are treating, or if you develop a rash or irritation, stop using the product immediately and consult your doctor.

Always prioritize your health and safety by following these guidelines closely. If you have any concerns or questions about your symptoms or the use of this product, don’t hesitate to reach out to a healthcare professional.

Overdose

It appears that there is no specific information available regarding overdosage for this medication. However, it's important to be aware of the general signs of an overdose, which can include symptoms like extreme drowsiness, confusion, or difficulty breathing. If you suspect an overdose, it is crucial to seek immediate medical help.

In case of an emergency, call your local emergency services or go to the nearest hospital. Always keep medications out of reach of children and follow the prescribed dosage to prevent any potential risks. If you have any concerns or questions about your medication, don’t hesitate to reach out to your healthcare provider for guidance.

Pregnancy Use

When it comes to using this medication during pregnancy, there is currently no information available about its safety, recommended dosage adjustments, or any special precautions you should take. This means that if you are pregnant or planning to become pregnant, it is essential to consult with your healthcare provider before using this medication. They can help you understand any potential risks and make informed decisions about your treatment options. Always prioritize your health and the health of your baby by seeking professional guidance.

Lactation Use

If you are breastfeeding, you can use ANAL-ESE desensitizer cream without specific warnings or recommendations against it. Currently, there is no information indicating that the cream is excreted in breast milk or that it poses any risk to your nursing infant. This means you can feel more at ease while using the product during this time.

Pediatric Use

It's important to keep this medication out of reach of children. This precaution helps prevent accidental ingestion, which can be dangerous. Always store it in a safe place where children cannot access it, ensuring their safety at all times. If you have any concerns or questions about the medication, don't hesitate to reach out to your healthcare provider for guidance.

Geriatric Use

When it comes to using this medication in older adults, there is no specific information available about dosage adjustments, safety concerns, or special precautions. This means that if you or a loved one is an older adult, it’s important to consult with a healthcare provider before starting the medication. They can help determine the best approach based on individual health needs and any other medications being taken. Always prioritize open communication with your healthcare team to ensure safe and effective treatment.

Renal Impairment

It appears that there is no specific information regarding dosage adjustments, monitoring, or safety considerations for patients with kidney problems in the provided text. This means that if you have renal impairment (kidney issues), you should consult your healthcare provider for personalized advice and recommendations regarding your treatment. They can help ensure that any medications you take are safe and effective for your condition. Always keep your doctor informed about your kidney health to receive the best care possible.

Hepatic Impairment

If you have liver problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or precautions for your condition. This means that there are no tailored guidelines for how this medication may affect you differently due to your liver health.

Always consult your healthcare provider for personalized advice and to ensure that any medication you take is safe and appropriate for your liver condition. They can help monitor your liver function and make any necessary adjustments to your treatment plan.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you. Always share your complete list of medications and any health conditions you have to receive the best care possible.

Storage and Handling

To ensure the safety and effectiveness of your product, store it at room temperature. It's important to keep it out of reach of children to prevent any accidental use. Remember, this product is intended for external use only, so avoid applying it internally. Following these guidelines will help you use the product safely and effectively.

Additional Information

This medication is intended for external use only and should not be applied near your eyes. It is important to avoid prolonged use. If you experience discomfort, or if a rash or irritation develops while using the product, stop using it immediately and consult your physician. This medication is specifically used for the prevention of premature ejaculation.

FAQ

What is ANAL-ESE?

ANAL-ESE is a desensitizing lubricant designed for less painful anal penetration.

What flavors does ANAL-ESE come in?

ANAL-ESE is available in a strawberry flavor.

How should I use ANAL-ESE?

Apply a small amount of ANAL-ESE to the rectal area prior to penetration and wait a few minutes for desensitization.

What are the warnings associated with ANAL-ESE?

ANAL-ESE is for external use only, should not be used near the eyes, and is not for prolonged use. Discontinue use if discomfort, rash, or irritation occurs.

Is there any information about using ANAL-ESE during pregnancy?

There is no specific information regarding the use of ANAL-ESE during pregnancy.

Can nursing mothers use ANAL-ESE?

There are no specific warnings or recommendations regarding the use of ANAL-ESE in nursing mothers.

What should I do if I experience discomfort while using ANAL-ESE?

If you experience discomfort, rash, or irritation, discontinue use and consult a physician.

How should I store ANAL-ESE?

Store ANAL-ESE at room temperature and keep it out of reach of children.

What is the route of administration for ANAL-ESE?

ANAL-ESE is administered topically.

Packaging Info

Below are the non-prescription pack sizes of Anal-Ese (desensitizer). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Anal-Ese.
Details

Drug Information (PDF)

This file contains official product information for Anal-Ese, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the specified drug.

Uses and Indications

This drug is indicated as a desensitizing lubricant for use in situations where less painful anal penetration is desired.

There are no teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

Healthcare professionals are advised to apply a small amount of ANAL-ESE to the rectal area prior to penetration. It is important to allow a few minutes for desensitization to occur before attempting penetration. The appropriate amount of product and the waiting time may vary and should be determined based on individual experience after several uses.

Contraindications

There are no contraindications associated with the use of this product. It is deemed safe for use in the absence of specific conditions or situations that would warrant avoidance.

Warnings and Precautions

For external use only. It is imperative that this preparation is not applied near the eyes to prevent potential irritation or injury. Prolonged use of this product is not recommended, as it may lead to adverse effects.

In the event that the condition for which the preparation is being used causes discomfort, or if any rash or irritation develops, it is essential to discontinue use immediately. Consultation with a physician is advised to ensure appropriate management and to evaluate the need for alternative treatments.

Side Effects

Patients should be aware that the product is intended for external use only and should not be applied near the eyes. Prolonged use of the product is not recommended. In clinical practice, if the condition for which the preparation is used causes discomfort, or if a rash or irritation develops, patients are advised to discontinue use immediately and consult a physician.

These precautions are essential to ensure the safety and well-being of patients using the product.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there are no known interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Anal-Ese (desensitizer). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Anal-Ese.
Details

Pediatric Use

Pediatric patients should be advised to keep this medication out of reach of children. It is essential to ensure that the medication is stored safely to prevent accidental ingestion or misuse.

Geriatric Use

Elderly patients may not have specific information regarding the use of this medication, including dosage adjustments, safety concerns, or special precautions. Therefore, healthcare providers should exercise caution when prescribing this medication to geriatric patients. It is advisable to monitor these patients closely for any adverse effects or changes in therapeutic response, given the lack of targeted data for this population.

Pregnancy

There is no information available regarding the use of this medication during pregnancy, including safety concerns, dosage modifications, or any special precautions that should be taken. Healthcare professionals are advised to consider the lack of data when prescribing this medication to pregnant patients and to weigh the potential risks and benefits. Women of childbearing potential should be counseled accordingly.

Lactation

There are no specific warnings or recommendations regarding the use of ANAL-ESE desensitizer cream in lactating mothers. Additionally, there are no statements concerning the potential for excretion of the product in breast milk or any associated risks to breastfed infants.

Renal Impairment

There is no information available regarding dosage adjustments, special monitoring, or safety considerations for patients with renal impairment. Healthcare professionals should exercise caution and consider the lack of specific guidance when prescribing to patients with reduced kidney function.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

In the absence of specific overdosage information, it is essential for healthcare professionals to remain vigilant regarding the potential for overdose with this medication. In cases where an overdose is suspected, immediate medical attention should be sought.

Healthcare providers are advised to monitor patients closely for any signs or symptoms that may arise from an overdose. These may include, but are not limited to, increased severity of known side effects, altered mental status, or any unusual physiological responses.

Management of an overdose should be guided by the clinical presentation of the patient. Supportive care is paramount, and symptomatic treatment should be initiated as necessary. Healthcare professionals should also consider contacting a poison control center for additional guidance on the management of overdose cases.

In summary, while specific overdosage information is not available, healthcare professionals should exercise caution, monitor for symptoms, and provide appropriate supportive care in the event of an overdose.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the use of the compound in these contexts.

Postmarketing Experience

No postmarketing experience details are available in the insert text.

Patient Counseling

Healthcare providers should advise patients to keep the medication out of reach of children to prevent accidental ingestion or misuse. It is important to emphasize the necessity of proper storage to ensure the safety of young children.

Storage and Handling

The product is supplied in a configuration suitable for external use only. It must be stored at room temperature to maintain its efficacy. Additionally, it is essential to keep the product out of reach of children to ensure safety during handling and storage.

Additional Clinical Information

The product is administered topically and is intended for external use only. Clinicians should advise patients not to apply the product near the eyes and to avoid prolonged use. If patients experience discomfort, rash, or irritation while using the preparation, they should discontinue use and consult a physician. The product is indicated for the prevention of premature ejaculation.

Drug Information (PDF)

This file contains official product information for Anal-Ese, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Anal-Ese, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.