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Alka-Seltzer Ultra Strength Heartburn Reliefchews

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Active ingredient
Calcium Carbonate 1000 mg
Other brand names
Drug classes
Blood Coagulation Factor, Phosphate Binder
Dosage form
Tablet, Chewable
Route
Oral
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2017
Label revision date
December 4, 2025
Drug Information (PDF)
Prescribing information, PDF file
Active ingredient
Calcium Carbonate 1000 mg
Other brand names
Drug classes
Blood Coagulation Factor, Phosphate Binder
Dosage form
Tablet, Chewable
Route
Oral
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2017
Label revision date
December 4, 2025
Manufacturer
Bayer HealthCare LLC.
Registration number
M001
NDC root
0280-0245
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info
Packaging & NDC Codes

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

Alka-Seltzer® is an antacid that contains calcium carbonate, which helps relieve discomfort caused by acid indigestion, heartburn, sour stomach, and upset stomach associated with these symptoms. It is designed to provide fast and powerful relief, making it a convenient option for those experiencing these common digestive issues.

This product comes in a chewable tablet form, known as RELIEFCHEWS®, and is available in a tropical twist flavor. Each package contains 50 chewable tablets, ensuring you have plenty on hand for when you need relief.

Uses

You can use this medication to help relieve discomfort from several common digestive issues. It is effective for alleviating acid indigestion, heartburn, sour stomach, and upset stomach that may accompany these symptoms.

If you're experiencing any of these digestive troubles, this medication may provide the relief you need to feel more comfortable.

Dosage and Administration

If you are an adult or a child aged 12 years and older, you can take 1 or 2 chewable tablets when you experience symptoms, or as your doctor advises. Make sure to chew the tablets completely before swallowing them. If you are caring for a child under 12 years old, it’s important to consult a doctor before giving them this medication.

Keep in mind that you should not exceed a maximum of 5 chewable tablets in a 24-hour period. This limit helps ensure your safety while using the medication effectively. Always follow the recommended dosage to avoid any potential issues.

What to Avoid

It's important to be aware of certain precautions when using this product. You should not use it if you have ever had an allergic reaction to it or any of its ingredients. Additionally, be mindful of the dosage: do not take more than 5 chewable tablets within a 24-hour period. If you find that you need to use the maximum dosage, do so only for a maximum of 2 weeks and under the guidance of a physician.

This product is classified as a controlled substance, which means it has the potential for abuse or misuse. It's crucial to follow these guidelines to avoid any dependence (a condition where your body becomes reliant on a substance) or other serious health issues. Always prioritize your safety and consult with a healthcare professional if you have any questions or concerns.

Side Effects

If you have a history of allergic reactions to this product or any of its ingredients, it’s important not to use it. While using this product, you might experience constipation, which is a common side effect. If you notice any unusual symptoms or have concerns, please consult your healthcare provider.

Warnings and Precautions

You should not use this product if you have ever had an allergic reaction to it or any of its ingredients. It's important to consult with your doctor or pharmacist before using this product, especially if you are currently taking any prescription medications, as antacids can interact with certain drugs. If you are pregnant or breastfeeding, please seek advice from a healthcare professional before using this product.

There are no specific laboratory tests required for this product. If you experience any unusual symptoms or have concerns while using it, be sure to stop taking it and reach out to your doctor for guidance.

Overdose

It appears that there is no specific information available regarding overdosage for this medication. However, it's always important to be aware of the signs of an overdose, which can include symptoms like extreme drowsiness, confusion, or difficulty breathing. If you suspect an overdose, it’s crucial to seek immediate medical help.

In case of an emergency, contact your local emergency services or go to the nearest hospital. Always keep medications out of reach of children and follow the prescribed dosage to prevent any potential risks. If you have any concerns or questions about your medication, don’t hesitate to reach out to your healthcare provider for guidance.

Pregnancy Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using this medication. They can provide guidance on whether it’s safe for you and your baby. Always prioritize your health and the health of your child by seeking expert advice.

Lactation Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using any medication. This ensures that you understand any potential risks and can make informed decisions about your health and the health of your baby. Always prioritize open communication with your doctor regarding your breastfeeding journey.

Pediatric Use

If you have a child under 12 years old, it's important to consult a doctor before giving them this medication. For children aged 12 and older, they can take 1 or 2 chewable tablets as needed for symptoms, but they should fully chew and then swallow the tablets. Always follow your doctor's guidance regarding dosage and usage.

Geriatric Use

When it comes to using this medication in older adults, there is no specific information available about dosage adjustments, safety concerns, or special precautions. This means that if you or a loved one is an older adult, it’s important to consult with a healthcare provider before starting the medication. They can help determine the best approach based on individual health needs and any other medications being taken. Always prioritize open communication with your healthcare team to ensure safe and effective treatment.

Renal Impairment

If you have kidney problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or safety considerations for your condition. This means that there are no tailored guidelines for how this medication may affect you if you have renal impairment (kidney issues).

Always consult your healthcare provider for personalized advice and to ensure that any medication you take is safe and appropriate for your health situation. They can help monitor your kidney function and make any necessary adjustments to your treatment plan.

Hepatic Impairment

If you have liver problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or precautions for your condition. This means that there are no tailored guidelines for how this medication may affect you if you have hepatic impairment (issues with liver function).

Always consult your healthcare provider for personalized advice and to discuss any concerns regarding your liver health and how it may relate to your treatment. They can help ensure that you receive the safest and most effective care.

Drug Interactions

It's important to be aware that some over-the-counter medications, like antacids containing calcium carbonate, can interact with prescription drugs. This means they might change how well those medications work in your body. To ensure you’re getting the most benefit from your treatments, it’s essential to discuss all the medications you’re taking, including any antacids, with your healthcare provider.

Always keep your healthcare team informed about your full list of medications and any changes you make. This way, they can help you avoid potential interactions and ensure your treatment is as effective as possible.

Storage and Handling

To ensure the best performance of your product, store it at room temperature and keep it away from humidity, as moisture can affect its effectiveness. After each use, make sure to close the cap tightly to maintain its integrity and prevent contamination.

By following these simple storage and handling tips, you can help ensure that your product remains safe and effective for your needs.

Additional Information

No further information is available.

FAQ

What is Alka-Seltzer® used for?

Alka-Seltzer® is used for the relief of acid indigestion, heartburn, sour stomach, and upset stomach associated with these symptoms.

What is the maximum dosage for adults and children over 12?

Adults and children 12 years and over should not take more than 5 chewable tablets in a 24-hour period.

How should I take Alka-Seltzer®?

You should fully chew then swallow 1 or 2 chewable tablets as symptoms occur, or as directed by a doctor.

Can children under 12 use Alka-Seltzer®?

Children under 12 years should consult a doctor before use.

Are there any warnings for using Alka-Seltzer®?

Do not use Alka-Seltzer® if you have ever had an allergic reaction to this product or any of its ingredients.

What should I do if I experience constipation while using Alka-Seltzer®?

Constipation may occur when using this product; if it becomes bothersome, consult a healthcare professional.

Is it safe to use Alka-Seltzer® if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, you should ask a health professional before using Alka-Seltzer®.

How should I store Alka-Seltzer®?

Store Alka-Seltzer® at room temperature and avoid humidity. Make sure to close the cap tightly after use.

Packaging Info

Below are the non-prescription pack sizes of Alka-Seltzer Ultra Strength Heartburn Reliefchews (calcium carbonate). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Alka-Seltzer Ultra Strength Heartburn Reliefchews.
Details

Drug Information (PDF)

This file contains official product information for Alka-Seltzer Ultra Strength Heartburn Reliefchews, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available.

Uses and Indications

This drug is indicated for the relief of acid indigestion, heartburn, sour stomach, and upset stomach associated with these symptoms.

There are no teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

Adults and children aged 12 years and over are advised to fully chew and then swallow 1 or 2 chewable tablets as symptoms occur, or as directed by a healthcare professional. For children under 12 years of age, it is recommended to consult a doctor prior to administration.

The maximum dosage should not exceed 5 chewable tablets within a 24-hour period.

Contraindications

Use of this product is contraindicated in individuals with a known allergy to the product or any of its ingredients.

Additionally, the following usage restrictions apply:

  • The maximum dosage should not exceed 5 chewable tablets within a 24-hour period.

  • The product should not be used at the maximum dosage for more than 2 weeks unless directed and supervised by a physician.

Warnings and Precautions

Patients with a known history of allergic reactions to this product or any of its ingredients should not use it. This contraindication is critical to prevent severe allergic responses.

Before initiating treatment, it is advisable for patients to consult with a healthcare professional, such as a doctor or pharmacist, particularly if they are currently taking any prescription medications. This is essential as antacids may interact with certain prescription drugs, potentially altering their effectiveness or increasing the risk of adverse effects.

For individuals who are pregnant or breastfeeding, it is important to seek guidance from a healthcare professional prior to use. This precaution ensures that the benefits and risks are carefully weighed in the context of maternal and fetal health.

While no specific laboratory tests are recommended for monitoring during the use of this product, healthcare providers should remain vigilant for any signs of adverse reactions or interactions, particularly in patients with complex medication regimens.

Side Effects

Patients should be aware that the use of this product is contraindicated in individuals who have a history of allergic reactions to the product or any of its ingredients.

In clinical experience, constipation has been reported as a common adverse reaction associated with the use of this product. Patients should be monitored for this effect, and appropriate measures should be taken to manage constipation if it occurs.

Drug Interactions

Antacids, particularly those containing calcium carbonate, may interact with certain prescription medications, potentially impacting their absorption and overall efficacy. It is advisable for healthcare professionals to monitor patients for any changes in therapeutic effects when these antacids are co-administered with other drugs. Adjustments to the timing of administration or dosage may be necessary to mitigate these interactions.

No additional drug interactions or interactions with laboratory tests have been reported.

Packaging & NDC

Below are the non-prescription pack sizes of Alka-Seltzer Ultra Strength Heartburn Reliefchews (calcium carbonate). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Alka-Seltzer Ultra Strength Heartburn Reliefchews.
Details

Pediatric Use

Pediatric patients under 12 years of age should consult a healthcare professional before use. For adolescents and adults aged 12 years and older, the recommended dosage is to fully chew and then swallow 1 or 2 chewable tablets as symptoms occur, or as directed by a healthcare provider.

Geriatric Use

There is no specific information regarding the use of this medication in geriatric patients, including dosage adjustments, safety concerns, or special precautions. Healthcare providers should exercise caution when prescribing this medication to elderly patients, as they may have altered pharmacokinetics and pharmacodynamics. Close monitoring is recommended to ensure safety and efficacy in this population.

Pregnancy

Pregnant patients and those who are breastfeeding should consult a healthcare professional prior to using this medication. The potential risks and benefits must be carefully considered, as the effects on fetal outcomes and lactation are not fully established. It is essential for women of childbearing potential to discuss their individual circumstances with their healthcare provider to ensure safe use during pregnancy and lactation.

Lactation

Lactating mothers are advised to consult a health professional prior to using this medication. There is currently no available data on the excretion of this drug in human breast milk or its effects on breastfed infants. Therefore, caution is recommended when administering this medication to lactating individuals.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the drug insert regarding dosage adjustments, special monitoring, or safety considerations. Therefore, healthcare professionals should exercise caution when prescribing this medication to patients with reduced kidney function, as the absence of detailed guidance necessitates careful clinical judgment. Regular monitoring of renal function may be advisable in these patients to ensure safety and efficacy.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

In the absence of specific overdosage information, it is essential for healthcare professionals to remain vigilant regarding the potential for overdose with this medication. In cases where an overdose is suspected, immediate medical attention should be sought.

Healthcare providers are advised to monitor patients closely for any signs or symptoms that may indicate an overdose. These may include, but are not limited to, altered mental status, cardiovascular instability, or gastrointestinal disturbances.

Management of an overdose should be guided by the clinical presentation of the patient. Supportive care is paramount, and symptomatic treatment should be initiated as necessary. It is recommended that healthcare professionals consult local poison control centers or relevant toxicology resources for further guidance on the management of overdose cases.

In summary, while specific overdosage data is not available, healthcare professionals should exercise caution and be prepared to act swiftly in the event of an overdose, ensuring that appropriate interventions are implemented based on the patient's condition.

Nonclinical Toxicology

There is currently no available information regarding teratogenic effects, non-teratogenic effects, or any specific findings in the nonclinical toxicology section. Additionally, there are no details provided concerning animal pharmacology and toxicology.

Postmarketing Experience

No postmarketing experience details are available in the insert text.

Patient Counseling

Patients should be advised to keep this product out of reach of children to prevent accidental ingestion. It is important to inform patients that they should not use this product if they have ever experienced an allergic reaction to it or any of its ingredients.

When discussing the usage of this product, healthcare providers should emphasize that patients must not exceed a maximum of 5 chewable tablets within a 24-hour period. Additionally, patients should be cautioned against using the maximum dosage for more than 2 weeks unless directed and supervised by a physician.

Patients should also be made aware that constipation may occur as a side effect of using this product. It is advisable for patients to consult with a doctor or pharmacist before using this product if they are currently taking any prescription medications, as antacids may interact with certain drugs.

Storage and Handling

The product is supplied in various package configurations, with specific NDC numbers available for identification. It should be stored at room temperature, ensuring that it is kept away from humidity to maintain its integrity. After each use, it is essential to close the cap tightly to prevent contamination and preserve the product's quality.

Additional Clinical Information

No further data are available.

Drug Information (PDF)

This file contains official product information for Alka-Seltzer Ultra Strength Heartburn Reliefchews, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Alka-Seltzer Ultra Strength Heartburn Reliefchews, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.