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Refresh Optive Advanced
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- Active ingredients
- Glycerin 10 mg/1 mL
- Carboxymethylcellulose Sodium 5 mg/1 mL
- Polysorbate 80 5 mg/1 mL
- Other brand names
- Drug class
- Non-Standardized Chemical Allergen
- Dosage form
- Solution/ Drops
- Route
- Ophthalmic
- Prescription status
- OTC (over the counter)
- Pregnancy
- See Pregnancy Use Section
- Lactation
- See Lactation Use Section
- Marketed in the U.S.
- Since 2013
- Label revision date
- September 15, 2022
- Drug Information (PDF)
- Prescribing information, PDF file
- Active ingredients
- Glycerin 10 mg/1 mL
- Carboxymethylcellulose Sodium 5 mg/1 mL
- Polysorbate 80 5 mg/1 mL
- Other brand names
- Drug class
- Non-Standardized Chemical Allergen
- Dosage form
- Solution/ Drops
- Route
- Ophthalmic
- Prescription status
- OTC (over the counter)
- CSA schedule
- Not a scheduled drug
- Pregnancy
- See Pregnancy Use Section
- Lactation
- See Lactation Use Section
- Marketed in the U.S.
- Since 2013
- Label revision date
- September 15, 2022
- Manufacturer
- Allergan, Inc.
- Registration number
- M018
- NDC root
- 0023-4491
- Drug Information (PDF)
- Prescribing information, PDF file
If you are a healthcare professional or from the pharmaceutical industry please visit this version.
If you are a consumer or patient please visit this version.
Drug Overview
Refresh OPTIVE® ADVANCED Lubricant Eye Drops are preservative-free eye drops designed to provide temporary relief from burning, irritation, and discomfort caused by dry eyes or exposure to wind and sun. They contain Hydrocell®, which helps to hydrate and protect your eyes, offering triple-action relief to keep your eyes feeling comfortable.
These eye drops come in convenient vials, each containing a sterile solution that can also act as a protectant against further irritation. If you experience dryness or discomfort in your eyes, these drops may be a helpful option to consider for soothing relief.
Uses
If you're experiencing burning, irritation, or discomfort in your eyes due to dryness or exposure to wind or sun, this product can provide temporary relief. It works by soothing your eyes and helping to alleviate those uncomfortable sensations.
Additionally, it may serve as a protective barrier against further irritation, ensuring your eyes stay comfortable in challenging conditions. You can use it to help maintain eye comfort throughout your day.
Dosage and Administration
When you need to treat your eye condition, simply instill 1 or 2 drops of the medication into the affected eye(s) as needed. It's important to remember to discard the container after use to ensure safety and effectiveness. This straightforward approach helps you manage your symptoms effectively while keeping your treatment hygienic.
What to Avoid
It's important to be aware of certain situations where you should not use this medication. Specifically, you should avoid using it if you experience eye pain, changes in your vision, ongoing redness or irritation of the eye, or if your condition worsens or does not improve after 72 hours.
While there are no specific contraindications or concerns about abuse, misuse, or dependence associated with this medication, always prioritize your health and consult a healthcare professional if you have any questions or concerns about your symptoms or treatment.
Side Effects
You should be aware that this product is for external use only. To prevent contamination, avoid touching the tip of the container to any surface, and do not reuse it once opened—discard it instead. If the solution changes color, do not use it.
If you experience eye pain, changes in vision, or ongoing redness or irritation of the eye, stop using the product and consult a doctor, especially if your condition worsens or does not improve within 72 hours. Keep this product out of reach of children, and if it is swallowed, seek medical help or contact a Poison Control Center immediately.
Warnings and Precautions
This product is for external use only, so please avoid using it in any other way. To keep it safe and effective, do not touch the tip of the container to any surface, and do not reuse it once opened—just discard it. Also, make sure not to touch the unit-dose tip to your eye, and if the solution changes color, do not use it.
You should stop using this product and contact your doctor if you experience any eye pain, changes in your vision, ongoing redness or irritation of the eye, or if your condition worsens or does not improve after 72 hours. If the product is swallowed, seek emergency medical help or contact a Poison Control Center immediately.
Overdose
If you or someone else has swallowed too much of a medication, it’s important to seek medical help immediately. You can do this by contacting a Poison Control Center or going to the nearest emergency room.
Signs of an overdose can vary, but they may include unusual drowsiness, confusion, or difficulty breathing. If you notice any of these symptoms, don’t hesitate to get help right away. Remember, acting quickly can make a significant difference in the outcome.
Pregnancy Use
If you are pregnant or planning to become pregnant, it's important to be aware that there is no specific information available about the use of this medication during pregnancy. This means that safety concerns, dosage adjustments, or any special precautions have not been established.
Before taking this medication, you should consult with your healthcare provider to discuss any potential risks and to ensure that you are making informed decisions for your health and the health of your baby. Always prioritize open communication with your doctor regarding any medications you may be considering during pregnancy.
Lactation Use
If you are breastfeeding, you can use Refresh Optive Advanced without specific warnings or recommendations. Currently, there is no information available about whether this product is excreted in breast milk or if it poses any risk to your nursing infant. As always, if you have concerns or questions about using any medication while breastfeeding, it's a good idea to consult with your healthcare provider for personalized advice.
Pediatric Use
It's important to keep this medication out of reach of children to prevent accidental ingestion. If your child swallows any of it, seek medical help immediately or contact a Poison Control Center for guidance. Taking these precautions can help ensure your child's safety.
Geriatric Use
When it comes to using this medication in older adults, there is no specific information available about how it may affect you or if any dosage adjustments are necessary. This means that the usual guidelines for safety and precautions that often apply to elderly patients are not detailed in the insert.
If you are an older adult or a caregiver, it's important to consult with a healthcare professional before starting this medication. They can provide personalized advice and ensure that it is safe and appropriate for your individual health needs.
Renal Impairment
If you have kidney problems, it's important to know that the information provided does not include specific guidelines for dosage adjustments, special monitoring, or safety considerations related to renal impairment (kidney issues). This means that there are no tailored recommendations for how your treatment may need to change based on your kidney function.
Always consult your healthcare provider for personalized advice and to ensure that your treatment plan is safe and effective for your specific situation. They can help monitor your kidney health and make any necessary adjustments to your medications.
Hepatic Impairment
If you have liver problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or precautions for your condition. This means that there are no tailored guidelines for how this medication may affect you if you have hepatic impairment (liver issues).
Always consult your healthcare provider for personalized advice and to discuss any concerns regarding your liver health and how it may relate to your treatment. They can help ensure that you receive the safest and most effective care.
Drug Interactions
It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you.
Always feel free to ask questions and share your complete list of medications and any lab tests you may be undergoing. This way, you can receive the best possible care tailored to your needs.
Storage and Handling
To ensure the safety and effectiveness of your product, always use it only if the single-use container is intact and has not been damaged. Be sure to check the expiration date marked on the container and use the product before that date. For proper storage, keep the product in a cool, dry place at a temperature between 59°F and 77°F (15°C and 25°C).
It's also important to retain the carton for future reference, as it may contain useful information. Following these guidelines will help you handle the product safely and effectively.
Additional Information
No further information is available.
FAQ
What is Refresh OPTIVE® ADVANCED Lubricant Eye Drops used for?
It is used for the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun.
How should I use Refresh OPTIVE® ADVANCED Lubricant Eye Drops?
Instill 1 or 2 drops in the affected eye(s) as needed and discard the container after use.
Are there any contraindications for using this eye drop?
No contraindications are listed for Refresh OPTIVE® ADVANCED Lubricant Eye Drops.
What should I do if I experience eye pain or changes in vision?
Stop using the drops and ask a doctor if you experience eye pain, changes in vision, continued redness or irritation, or if the condition worsens or persists for more than 72 hours.
Is Refresh OPTIVE® ADVANCED safe to use during pregnancy?
There is no specific information regarding the use of Refresh OPTIVE® ADVANCED during pregnancy.
Can nursing mothers use Refresh OPTIVE® ADVANCED?
There are no specific warnings or recommendations regarding the use of Refresh OPTIVE® ADVANCED in nursing mothers.
What should I do if I accidentally swallow the eye drops?
If swallowed, get medical help or contact a Poison Control Center right away.
How should I store Refresh OPTIVE® ADVANCED Lubricant Eye Drops?
Store the eye drops at 59°-77°F (15°-25°C) and use only if the single-use container is intact.
What are the warnings associated with Refresh OPTIVE® ADVANCED?
It is for external use only, and you should avoid touching the tip of the container to any surface or your eye. If the solution changes color, do not use it.
Packaging Info
Below are the non-prescription pack sizes of Refresh Optive Advanced (carboxymethylcellulose sodium, glycerin, polysorbate 80). Columns show Packaging, Formulation Type, and Active Ingredient Strength.
Details | ||||
|---|---|---|---|---|
| Solution/ Drops |
| ||
Product details Regulatory status — Marketed All current FDA data sets list this NDC as actively marketed. FDA record dates for this NDC:
Active ingredients
Inactive ingredients
| ||||
| Solution/ Drops |
| ||
Product details Regulatory status — Marketed All current FDA data sets list this NDC as actively marketed. FDA record dates for this NDC:
Active ingredients
Inactive ingredients
| ||||
Drug Information (PDF)
This file contains official product information for Refresh Optive Advanced, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.
Description
No description information is available for the specified drug.
Uses and Indications
This drug is indicated for the temporary relief of burning, irritation, and discomfort associated with dryness of the eye or exposure to wind or sun. It may also be utilized as a protectant against further irritation.
There are no teratogenic or nonteratogenic effects associated with this drug.
Dosage and Administration
Healthcare professionals are advised to instill 1 or 2 drops of the medication into the affected eye(s) as needed. After use, the container should be discarded to ensure proper hygiene and prevent contamination.
Contraindications
Use is contraindicated in patients experiencing eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours.
Warnings and Precautions
For external use only. To prevent contamination, it is imperative that the tip of the container is not allowed to come into contact with any surface. The container should not be reused; once opened, it must be discarded. Additionally, the unit-dose tip should not be applied directly to the eye. If there is any change in the color of the solution, it should not be used.
Healthcare professionals should advise patients to discontinue use and seek medical attention if they experience any of the following symptoms: eye pain, changes in vision, persistent redness or irritation of the eye, or if the condition worsens or does not improve within 72 hours.
In the event of accidental ingestion, immediate medical assistance should be sought, or the local Poison Control Center should be contacted without delay.
Side Effects
Patients using this product may experience various adverse reactions. It is important to note that the product is intended for external use only. To prevent contamination, patients should avoid touching the tip of the container to any surface and should not reuse the container once opened; it should be discarded immediately.
Serious adverse reactions may include eye pain, changes in vision, or continued redness or irritation of the eye. Patients are advised to stop use and consult a doctor if they experience any of these symptoms, or if their condition worsens or persists for more than 72 hours.
In the event that the solution changes color, it should not be used. Additionally, this product should be kept out of reach of children. If swallowed, patients should seek medical help or contact a Poison Control Center immediately.
Drug Interactions
There are currently no documented drug interactions associated with the use of this medication. Additionally, there are no known interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.
Packaging & NDC
Below are the non-prescription pack sizes of Refresh Optive Advanced (carboxymethylcellulose sodium, glycerin, polysorbate 80). Columns show Packaging, Formulation Type, and Active Ingredient Strength.
Details | ||||
|---|---|---|---|---|
| Solution/ Drops |
| ||
Product details Regulatory status — Marketed All current FDA data sets list this NDC as actively marketed. FDA record dates for this NDC:
Active ingredients
Inactive ingredients
| ||||
| Solution/ Drops |
| ||
Product details Regulatory status — Marketed All current FDA data sets list this NDC as actively marketed. FDA record dates for this NDC:
Active ingredients
Inactive ingredients
| ||||
Pediatric Use
Pediatric patients should be advised to keep this medication out of reach of children. In the event of accidental ingestion, immediate medical assistance should be sought, or the Poison Control Center should be contacted without delay.
Geriatric Use
Elderly patients may not have specific information regarding the use of this medication, including dosage adjustments, safety concerns, or special precautions. Therefore, healthcare providers should exercise caution when prescribing this medication to geriatric patients. It is advisable to monitor these patients closely for any adverse effects or changes in therapeutic response, given the lack of targeted data for this population.
Pregnancy
There is no specific information regarding the use of this medication during pregnancy, including safety concerns, dosage modifications, or special precautions. Healthcare professionals should consider the lack of data when prescribing this medication to pregnant patients. The potential risks and benefits should be carefully evaluated, and alternative treatments may be considered in consultation with the patient. Women of childbearing potential should be advised to discuss their pregnancy status and any plans for pregnancy with their healthcare provider prior to initiating treatment.
Lactation
There are no specific warnings or recommendations regarding the use of Refresh Optive Advanced in lactating mothers. Additionally, there is no information available concerning the potential for excretion of the product in breast milk or any associated risks to breastfed infants.
Renal Impairment
Patients with renal impairment have not been specifically addressed in the available prescribing information. There are no dosage adjustments, special monitoring requirements, or safety considerations outlined for individuals with reduced kidney function. Healthcare professionals should exercise caution and consider the lack of data when prescribing to this patient population.
Hepatic Impairment
Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.
Overdosage
In the event of an overdosage, immediate medical assistance is crucial. If the substance is ingested, healthcare professionals should advise patients or caregivers to seek medical help or contact a Poison Control Center without delay.
Prompt intervention is essential to mitigate potential adverse effects associated with overdosage. Symptoms may vary depending on the specific substance involved; therefore, a thorough assessment by a medical professional is recommended to determine the appropriate course of action.
Management procedures may include supportive care and symptomatic treatment, tailored to the individual patient's needs. Continuous monitoring and evaluation are advised to ensure patient safety and effective resolution of any complications arising from the overdosage.
Nonclinical Toxicology
No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the use of the compound in these contexts.
Postmarketing Experience
No postmarketing experience details are provided in the insert for Refresh Optive Advanced.
Patient Counseling
Healthcare providers should advise patients to keep the medication out of reach of children to prevent accidental ingestion. Instruct patients that if the medication is swallowed, they should seek medical help or contact a Poison Control Center immediately.
Additionally, healthcare providers should inform patients to discontinue use and consult a doctor if they experience any of the following symptoms: eye pain, changes in vision, persistent redness or irritation of the eye, or if their condition worsens or does not improve after 72 hours. This guidance is essential to ensure patient safety and effective management of their condition.
Storage and Handling
The product is supplied in single-use containers, which should only be utilized if the container remains intact. It is essential to adhere to the expiration date indicated on the container to ensure product efficacy.
For optimal storage conditions, the product must be kept at a temperature range of 59° to 77°F (15° to 25°C). Additionally, it is advised to retain the carton for future reference, as it may contain important information regarding the product.
Additional Clinical Information
No further data are available.
Drug Information (PDF)
This file contains official product information for Refresh Optive Advanced, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.