Clean and Clear Advantage Acne Spot Treatment

Description

Clean & Clear® Advantage Acne Spot Treatment is an oil-free formulation designed for the treatment of acne. The active ingredient, salicylic acid, is known for its efficacy in addressing acne lesions. This product also contains witch hazel, which may contribute to its soothing properties. The treatment is packaged in a 0.75 fluid ounce (22 mL) container. Clinical observations indicate that 100% of participants demonstrated clearer skin within one day of use, while the formulation is designed to avoid overdrying the skin.

Uses and Indications

This drug is indicated for the treatment of acne. There are no teratogenic effects associated with its use, and no nonteratogenic effects have been reported.

Dosage and Administration

Healthcare professionals should ensure that the skin is thoroughly cleaned prior to the application of this product. The recommended application involves covering the entire affected area with a thin layer. This can be done one to three times daily, depending on the patient's needs and the physician's guidance.

To minimize the risk of excessive drying of the skin, it is advisable to initiate treatment with one application per day. Based on the patient's response and tolerance, the frequency may be gradually increased to two or three times daily as necessary or as directed by a healthcare provider.

In cases where bothersome dryness or peeling occurs, it is recommended to reduce the frequency of application to once daily or every other day to alleviate these side effects.

Contraindications

Use is contraindicated in children due to the risk of accidental ingestion. In the event of swallowing, immediate medical assistance should be sought or contact with a Poison Control Center is advised.

Warnings and Precautions

For external use only. This product is flammable; therefore, it must be kept away from open fire or flame to prevent any risk of ignition.

Skin irritation and dryness may be exacerbated if this product is used concurrently with other topical acne medications. It is advised that only one topical acne medication be utilized at a time to minimize the risk of irritation.

In the event of eye contact, it is imperative to flush the eyes thoroughly with water to mitigate potential damage.

This product should be stored out of reach of children. In the case of accidental ingestion, immediate medical assistance should be sought, or contact with a Poison Control Center is recommended without delay.

Side Effects

Patients using this product should be aware of several important warnings and potential adverse reactions. This product is for external use only and is flammable; therefore, it should be kept away from open fire or flame.

Common adverse reactions include skin irritation and dryness, which are more likely to occur if another topical acne medication is used concurrently. In such cases, it is advised that only one topical acne medication be used at a time to minimize the risk of irritation.

In the event of eye contact, it is crucial to flush the eyes thoroughly with water to mitigate any potential harm.

Additionally, if the product is swallowed, patients should seek medical assistance or contact a Poison Control Center immediately. These precautions are essential to ensure the safe use of the product and to address any adverse reactions that may arise.

Drug Interactions

The concurrent use of multiple topical acne medications may increase the risk of skin irritation and dryness. To mitigate this risk, it is advised that only one topical acne medication be used at a time. If irritation occurs, discontinuation of additional topical agents is recommended to allow the skin to recover. Monitoring for signs of irritation is essential when initiating or adjusting treatment regimens involving topical acne therapies.

Packaging & NDC

Below are the non-prescription pack sizes of Clean and Clear Advantage Acne Spot Treatment (salicylic acid). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Pediatric Use

Pediatric patients should be advised to keep this medication out of reach of children. In the event of accidental ingestion, immediate medical assistance should be sought, or contact with a Poison Control Center is recommended.

Geriatric Use

There is no specific information regarding the use of Clean & Clear Advantage Acne Spot Treatment in geriatric patients. The prescribing information does not provide details on dosage adjustments, safety concerns, or special precautions for elderly patients. Therefore, healthcare providers should exercise caution and consider individual patient factors when prescribing this treatment to geriatric patients, as the absence of data necessitates careful monitoring and assessment of treatment efficacy and safety in this population.

Pregnancy

There is no information available regarding the use of Clean & Clear Advantage Acne Spot Treatment during pregnancy. As such, the safety of this product in pregnant patients has not been established, and there are no specific dosage modifications or special precautions recommended for use in this population. Healthcare professionals should consider the lack of data when advising women of childbearing potential and weigh the potential risks versus benefits of treatment during pregnancy.

Lactation

There are no specific warnings or recommendations regarding the use of this product by lactating mothers. Additionally, there is no information available about the potential for excretion in breast milk or any associated risks to breastfed infants.

Renal Impairment

There is no information available regarding dosage adjustments, special monitoring, or safety considerations for patients with renal impairment. Healthcare professionals should exercise caution and consider the lack of specific guidance when prescribing to patients with reduced kidney function.

Hepatic Impairment

There is no information available regarding hepatic impairment, including dosage adjustments, special monitoring, or precautions for patients with compromised liver function. Therefore, no specific recommendations can be made for the use of this medication in patients with hepatic impairment. It is advised that healthcare professionals exercise caution and consider individual patient circumstances when prescribing this medication to patients with liver problems.

Overdosage

In the event of an overdosage, immediate medical intervention is crucial. If the substance is ingested, it is imperative to seek medical assistance or contact a Poison Control Center without delay.

Healthcare professionals should be aware that prompt action can significantly influence the outcome of an overdosage situation. Symptoms of overdosage may vary depending on the specific substance involved; therefore, a thorough assessment and monitoring of the patient are essential.

Management procedures may include supportive care and symptomatic treatment, tailored to the individual patient's needs. Continuous evaluation and appropriate interventions should be implemented based on the clinical presentation and severity of symptoms.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data in these areas limits the understanding of the compound's potential effects in nonclinical settings.

Postmarketing Experience

No postmarketing experience details are provided in the insert.

Patient Counseling

Healthcare providers should advise patients to keep the medication out of reach of children to prevent accidental ingestion. In the event of swallowing the medication, patients should seek medical assistance or contact a Poison Control Center immediately.

Patients should be informed that the use of this medication may lead to skin irritation and dryness, particularly if they are using another topical acne medication concurrently. It is recommended that patients use only one topical acne medication at a time to minimize the risk of irritation.

Additionally, healthcare providers should instruct patients on the importance of avoiding eye contact with the medication. If contact occurs, patients should be advised to flush the eyes thoroughly with water to ensure safety and reduce potential discomfort.

Storage and Handling

The product is supplied in various package configurations, with specific NDC numbers available for identification. It is essential to store the product at room temperature to maintain its integrity and efficacy. No special handling requirements are noted, ensuring straightforward management within standard storage conditions.

Additional Clinical Information

No further data are available.

Drug Information (PDF)

This file contains official product information for Clean and Clear Advantage Acne Spot Treatment, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)