Symptom checker
Select audience type

Switch between content for healthcare professionals (PRO) and general audience (GEN).

ADD CONDITION

items per page

Cvs Lidocaine Pain Relief Cream

Last content change checked dailysee data sync status

Active ingredient
Lidocaine Hydrochloride 40 mg/1 g
Other brand names
Drug classes
Amide Local Anesthetic, Antiarrhythmic
Dosage form
Cream
Route
Topical
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2026
Label revision date
January 16, 2026
Drug Information (PDF)
Prescribing information, PDF file
Active ingredient
Lidocaine Hydrochloride 40 mg/1 g
Other brand names
Drug classes
Amide Local Anesthetic, Antiarrhythmic
Dosage form
Cream
Route
Topical
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2026
Label revision date
January 16, 2026
Manufacturer
CVS Pharmacy
Registration number
M017
NDC root
51316-379
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info
Packaging & NDC Codes

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

Lidocaine Pain Relief Cream is a topical analgesic that contains 4% lidocaine hydrochloride, which is the maximum strength available without a prescription. This cream is designed to temporarily relieve minor pain by numbing the affected area, providing non-irritating and non-greasy pain relief. It is fragrance-free and comes in a 4.3 oz bottle, making it a convenient option for those seeking effective pain management.

As an external analgesic, Lidocaine Pain Relief Cream is comparable to other over-the-counter products like Aspercreme with Lidocaine. It is particularly useful for targeting localized pain, helping you feel more comfortable in your daily activities.

Uses

You can use this medication to temporarily relieve minor pain. It’s designed to help you feel more comfortable when dealing with everyday aches and discomforts. Rest assured, there are no known teratogenic effects (which means it doesn’t cause birth defects) associated with this medication.

Dosage and Administration

For adults and children over 12 years old, you should apply a thin layer of the medication to the affected area every 6 to 8 hours. However, make sure not to exceed three applications within a 24-hour period. After applying, gently massage the medication into the painful area until it is fully absorbed into your skin.

If you are considering using this medication for a child who is 12 years old or younger, it’s important to consult a doctor first to ensure it’s safe and appropriate for them.

What to Avoid

You should avoid using this product if you have serious foot problems, such as ulcers or infections, or if you plan to apply it to large areas of your body, cut, irritated, or swollen skin, or puncture wounds. It's also important not to use it for more than one week without consulting your doctor.

While using this product, make sure to keep it away from your eyes and any mucus membranes. Avoid tightly bandaging the area or applying local heat, like heating pads or medicated patches, and do not use it alongside other topical analgesics (pain-relieving medications applied to the skin).

Side Effects

You should be aware that this product is for external use only and should not be applied to serious foot problems like ulcers or infections, large areas of the body, or on cut, irritated, or swollen skin. Avoid using it on puncture wounds and do not use it for more than one week without consulting a doctor. While using this product, make sure to follow all directions carefully, avoid contact with your eyes and mucous membranes, and do not apply tight bandages or heat to the treated area.

If you notice that your condition worsens, experience redness or irritation, or if symptoms last more than seven days or return shortly after improvement, stop using the product and consult a doctor. If you are pregnant or breastfeeding, it's important to speak with a healthcare professional before use. Keep this product out of reach of children, and if swallowed, seek medical help or contact a Poison Control Center immediately.

Warnings and Precautions

This product is for external use only, so please avoid applying it to your eyes or ingesting it. Do not use it if you have serious foot problems like ulcers or infections, on large areas of your body, or on any cut, irritated, or swollen skin. Additionally, avoid using it on puncture wounds and do not use it for more than one week without consulting your doctor.

If your condition worsens, if you notice redness or irritation, or if your symptoms last longer than 7 days or return shortly after improvement, stop using the product and contact your doctor. Always keep this product out of reach of children. If swallowed, seek medical help or contact a Poison Control Center immediately.

Overdose

If you or someone else has swallowed a medication and you suspect an overdose, it’s important to act quickly. Contact a medical professional or call a Poison Control Center immediately for guidance. They can provide you with the necessary steps to take based on the situation.

Signs of an overdose can vary, but they may include unusual symptoms that are not typical for the medication. If you notice any concerning changes in behavior or health, don’t hesitate to seek immediate medical attention. Your safety is the top priority, so getting help quickly can make a significant difference.

Pregnancy Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using this medication. They can provide guidance on whether it’s safe for you and your baby. Always prioritize your health and the health of your child by seeking expert advice.

Lactation Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using any medication. This ensures that you understand any potential risks and can make informed decisions about your health and the health of your baby. Always prioritize open communication with your doctor regarding your breastfeeding journey.

Pediatric Use

If you have a child who is 12 years old or younger, it's important to consult with a doctor before using this medication. For those over 12 years, you can apply a thin layer of the medication to the affected area every 6 to 8 hours. However, be sure not to exceed three applications within a 24-hour period to ensure safety and effectiveness. Always follow these guidelines to help protect your child's health.

Geriatric Use

When it comes to using this medication in older adults, there is no specific information available about dosage adjustments, safety concerns, or special precautions. This means that if you or a loved one is an older adult considering this medication, it’s important to consult with a healthcare provider. They can help determine the best approach based on individual health needs and any other medications being taken.

Always keep in mind that older adults may have different responses to medications, so discussing any concerns with a doctor is essential for ensuring safety and effectiveness.

Renal Impairment

If you have kidney problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or safety considerations for your condition. This means that there are no tailored guidelines for how this medication may affect you if you have renal impairment (kidney issues).

Always consult your healthcare provider for personalized advice and to ensure that any medication you take is safe and appropriate for your health situation. They can help monitor your kidney function and make any necessary adjustments to your treatment plan.

Hepatic Impairment

If you have liver problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or precautions for your condition. This means that there are no tailored guidelines for how this medication should be used if you have hepatic impairment (liver issues).

Before starting any new medication, including this one, you should discuss your liver health with your healthcare provider. They can help determine the best approach for your treatment and ensure your safety.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you. Always share your complete list of medications and any recent lab tests to avoid any potential issues. Your health and safety should always come first.

Storage and Handling

To ensure the best performance and safety of your product, store it in a cool, dry area. This helps maintain its effectiveness and prevents any potential damage. After each use, make sure to close the cap tightly to protect the contents from contamination and maintain their quality.

By following these simple storage and handling guidelines, you can help ensure that your product remains safe and effective for your needs.

Additional Information

No further information is available.

FAQ

What is Lidocaine Pain Relief Cream used for?

Lidocaine Pain Relief Cream is used to temporarily relieve minor pain.

How does Lidocaine Pain Relief Cream work?

It contains Lidocaine HCl 4%, which numbs pain and provides non-irritating, non-greasy pain relief.

Who can use this cream?

Adults and children over 12 years can use it, but children 12 years or younger should ask a doctor.

How should I apply Lidocaine Pain Relief Cream?

Apply a thin layer to the affected area every 6 to 8 hours, not exceeding 3 applications in a 24-hour period.

Are there any warnings for using this cream?

Yes, do not use it on large areas, on cut or irritated skin, or for more than one week without consulting a doctor.

What should I do if I experience side effects?

Stop use and ask a doctor if your condition worsens, if redness or irritation develops, or if symptoms persist for more than 7 days.

Is it safe to use during pregnancy or breastfeeding?

You should ask a health professional before using it if you are pregnant or breastfeeding.

How should I store Lidocaine Pain Relief Cream?

Store it in a cool, dry area and close the cap tightly after use.

What should I do if the cream is swallowed?

Keep it out of reach of children and seek medical help or contact a Poison Control Center immediately if swallowed.

Packaging Info

Below are the non-prescription pack sizes of Cvs Lidocaine Pain Relief Cream (lidocaine hydrochloride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Cvs Lidocaine Pain Relief Cream.
Details

Drug Information (PDF)

This file contains official product information for Cvs Lidocaine Pain Relief Cream, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the specified drug.

Uses and Indications

This drug is indicated for the temporary relief of minor pain.

There are no teratogenic effects associated with this drug. Additionally, no nonteratogenic effects have been reported.

Dosage and Administration

For adults and children over 12 years of age, a thin layer of the medication should be applied to the affected area every 6 to 8 hours. The total number of applications must not exceed 3 times within a 24-hour period. It is important to massage the medication into the painful area until it is thoroughly absorbed into the skin.

For children 12 years of age or younger, it is advised to consult a doctor before use.

Contraindications

Use of this product is contraindicated in patients with serious foot problems, including ulcers or infections, due to the potential for exacerbation of these conditions. Application on large areas of the body is not recommended, as it may lead to systemic absorption and increased risk of adverse effects. The product should not be applied to cut, irritated, or swollen skin, nor on puncture wounds, as this may cause further irritation or complications.

Additionally, the product should not be used for more than one week without consulting a healthcare professional to avoid potential misuse or complications. During use, contact with the eyes and mucous membranes must be avoided to prevent irritation. Tight bandaging, application of local heat (such as heating pads), or use of a medicated patch on the treated area is contraindicated, as these practices may enhance absorption and increase the risk of side effects. Concurrent use with other topical analgesics is also contraindicated to prevent additive effects and potential toxicity.

Warnings and Precautions

For external use only. This product is contraindicated in patients with serious foot problems, including ulcers or infections. It should not be applied to large areas of the body, nor should it be used on cut, irritated, or swollen skin, or on puncture wounds. Prolonged use beyond one week is not recommended without prior consultation with a healthcare professional.

Healthcare providers should advise patients to discontinue use and seek medical attention if any of the following occur: worsening of the condition, presence of redness, development of irritation, or if symptoms persist for more than seven days or resolve only to recur within a few days.

It is imperative to keep this product out of reach of children. In the event of accidental ingestion, immediate medical assistance should be sought, or contact with a Poison Control Center is advised.

Side Effects

Patients should be aware that this product is intended for external use only. It is contraindicated in individuals with serious foot problems, such as ulcers or infections, and should not be applied to large areas of the body, cut, irritated, or swollen skin, or puncture wounds. The product should not be used for more than one week without consulting a healthcare professional.

When using this product, it is essential to adhere strictly to the directions provided. Patients should avoid contact with the eyes and mucous membranes, and should not apply tight bandages or local heat, such as heating pads or medicated patches, to the area of application. Concurrent use with other topical analgesics is also not recommended.

Patients are advised to discontinue use and consult a doctor if the condition worsens, if redness or irritation develops, or if symptoms persist for more than seven days or resolve and then recur within a few days.

For pregnant or breastfeeding individuals, it is recommended to seek advice from a healthcare professional prior to use. Additionally, this product should be kept out of reach of children. In the event of accidental ingestion, immediate medical assistance should be sought or contact with a Poison Control Center should be made.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there is no information available regarding interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Cvs Lidocaine Pain Relief Cream (lidocaine hydrochloride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Cvs Lidocaine Pain Relief Cream.
Details

Pediatric Use

Pediatric patients 12 years of age or younger should consult a healthcare professional before use. For adolescents and children over 12 years, the recommended dosage is to apply a thin layer to the affected area every 6 to 8 hours, with a maximum of 3 applications within a 24-hour period.

Geriatric Use

Elderly patients may not have specific information regarding the use of this medication, including dosage adjustments, safety concerns, or special precautions. Therefore, healthcare providers should exercise caution when prescribing this medication to geriatric patients. It is advisable to monitor these patients closely for any adverse effects or changes in therapeutic response, given the lack of targeted data for this population.

Pregnancy

Pregnant patients and those who are breastfeeding should consult a healthcare professional before using this medication. The safety of this drug during pregnancy has not been established, and potential risks to fetal outcomes are not fully known. Therefore, it is essential for women of childbearing potential to seek medical advice prior to use to ensure appropriate management and consideration of any potential risks.

Lactation

Lactating mothers are advised to consult a health professional prior to using this medication. There is currently no available data regarding the excretion of this medication in human breast milk or its effects on breastfed infants. Therefore, caution is recommended when administering this medication to lactating individuals.

Renal Impairment

Patients with renal impairment have no specific information regarding dosage adjustments, special monitoring, or safety considerations provided in the drug insert. Therefore, healthcare professionals should exercise caution when prescribing this medication to individuals with reduced kidney function, as the lack of data necessitates careful clinical judgment. Regular monitoring of renal function may be advisable in these patients to ensure safety and efficacy.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the prescribing information.

Overdosage

In the event of an overdosage, immediate medical assistance is crucial. If the substance is ingested, healthcare professionals should advise patients or caregivers to seek medical help or contact a Poison Control Center without delay.

Prompt intervention is essential to mitigate potential adverse effects associated with overdosage. Symptoms may vary depending on the specific substance involved; therefore, a thorough assessment by a medical professional is recommended to determine the appropriate course of action.

Management procedures may include supportive care and symptomatic treatment, tailored to the individual patient's needs. Continuous monitoring and evaluation are vital to ensure patient safety and effective recovery.

Nonclinical Toxicology

If pregnant or breast-feeding, it is advised to consult a health professional prior to use. No non-teratogenic effects have been specified. Additionally, there are no details provided regarding nonclinical toxicology or animal pharmacology and toxicology.

Postmarketing Experience

No postmarketing experience details are available in the insert text.

Patient Counseling

Healthcare providers should advise patients to seek immediate medical assistance or contact a Poison Control Center if the product is swallowed. It is important to inform patients that the product should not be used if they have serious foot problems, such as ulcers or infections, and should not be applied to large areas of the body.

Patients should be cautioned against using the product on cut, irritated, or swollen skin, as well as on puncture wounds. They should be instructed not to use the product for more than one week without consulting a doctor. If the condition worsens, if redness is present, or if irritation develops, patients should be advised to stop use and consult a healthcare professional. Additionally, if symptoms persist for more than seven days or if they clear up and then recur within a few days, patients should seek medical advice.

When using this product, patients must be reminded to follow all directions and warnings on the carton carefully. They should avoid contact with the eyes and mucous membranes. Furthermore, patients should not bandage the area tightly or apply local heat, such as heating pads or medicated patches, to the area of use. It is also essential to inform patients not to use this product simultaneously with other topical analgesics.

Storage and Handling

The product is supplied in a secure container designed to maintain its integrity. It is essential to store the product in a cool, dry area to ensure optimal stability and efficacy. After each use, the cap must be closed tightly to prevent contamination and preserve the quality of the product.

Additional Clinical Information

No further data are available.

Drug Information (PDF)

This file contains official product information for Cvs Lidocaine Pain Relief Cream, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Cvs Lidocaine Pain Relief Cream, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.