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Tussin Cf

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Active ingredients
  • Guaifenesin 200 mg/10 mL
  • Dextromethorphan Hydrobromide 20 mg/10 mL
  • Phenylephrine Hydrochloride 10 mg/10 mL
Other brand names
Drug classes
Expectorant, Sigma-1 Agonist, Uncompetitive N-methyl-D-aspartate Receptor Antagonist, alpha-1 Adrenergic Agonist
Dosage form
Liquid
Route
Oral
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2024
Label revision date
March 21, 2024
Drug Information (PDF)
Prescribing information, PDF file
Active ingredients
  • Guaifenesin 200 mg/10 mL
  • Dextromethorphan Hydrobromide 20 mg/10 mL
  • Phenylephrine Hydrochloride 10 mg/10 mL
Other brand names
Drug classes
Expectorant, Sigma-1 Agonist, Uncompetitive N-methyl-D-aspartate Receptor Antagonist, alpha-1 Adrenergic Agonist
Dosage form
Liquid
Route
Oral
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2024
Label revision date
March 21, 2024
Manufacturer
Best Choice (Valu Merchandisers Company)
Registration number
M012
NDC root
63941-823
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info
Packaging & NDC Codes

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

Adult Tussin Multi-Symptom Cold CF is a medication designed to help relieve multiple symptoms associated with the common cold. It contains three active ingredients: Dextromethorphan HBr (20 mg), which acts as a cough suppressant; Guaifenesin (200 mg), an expectorant that helps loosen phlegm (mucus) and thin bronchial secretions for easier drainage; and Phenylephrine HCl (10 mg), a nasal decongestant that alleviates nasal congestion.

This non-drowsy formula is suitable for individuals aged 12 years and older and is alcohol-free. It temporarily relieves symptoms such as nasal congestion and cough caused by minor throat and bronchial irritation, making it a helpful option when you're feeling under the weather.

Uses

This medication is designed to help you breathe easier by loosening phlegm (mucus) and thinning bronchial secretions, which allows for better drainage of your bronchial tubes. If you're experiencing symptoms from a cold, such as nasal congestion or a cough caused by minor irritation in your throat and bronchial area, this medication can provide temporary relief.

It's important to note that this medication has not been associated with teratogenic effects (which means it does not cause birth defects) or nonteratogenic effects. Always consult with your healthcare provider if you have any questions or concerns about using this medication.

Dosage and Administration

When using this medication, it's important to follow the dosing instructions carefully. For adults and children aged 12 years and older, you should take 10 milliliters (mL) every 4 hours. However, make sure not to exceed 6 doses within a 24-hour period. To ensure accurate dosing, always use the dosing cup that comes with the product; do not use any other measuring device.

Please note that this medication is not suitable for children under 12 years of age, so if you're caring for younger children, do not use this product for them. Keep the dosing cup with the medication to help you measure the correct amount each time.

What to Avoid

You should not use this product if you are currently taking a prescription monoamine oxidase inhibitor (MAOI), which is a type of medication used for depression, psychiatric or emotional conditions, or Parkinson’s disease. Additionally, you must wait at least two weeks after stopping an MAOI before using this product. If you're unsure whether your prescription includes an MAOI, please consult your doctor or pharmacist for clarification. It's important to follow these guidelines to ensure your safety and well-being.

Side Effects

You should be aware of some potential side effects when using this medication. If you experience nervousness, dizziness, or sleeplessness, it's important to stop using the product and consult a doctor. Additionally, if your symptoms do not improve within 7 days, or if you develop a fever, or if your cough lasts more than 7 days, returns, or is accompanied by fever, rash, or a persistent headache, seek medical advice as these could indicate a more serious condition.

Before using this medication, consult your doctor if you have any of the following: heart disease, diabetes, high blood pressure, thyroid disease, a chronic cough (such as from smoking, asthma, chronic bronchitis, or emphysema), a cough with excessive mucus, or difficulty urinating due to an enlarged prostate. Also, do not use this medication if you are currently taking a prescription monoamine oxidase inhibitor (MAOI) or have taken one in the past two weeks, as this could lead to serious interactions.

Warnings and Precautions

You should not use this product if you are currently taking a prescription monoamine oxidase inhibitor (MAOI) for depression, psychiatric conditions, or Parkinson’s disease, or if you have stopped taking an MAOI within the last two weeks. If you are unsure whether your medication contains an MAOI, please consult your doctor or pharmacist.

Before using this product, it’s important to ask your doctor if you have any of the following conditions: heart disease, diabetes, high blood pressure, thyroid disease, a chronic cough (such as from smoking or asthma), a cough with excessive mucus, or difficulty urinating due to an enlarged prostate. Additionally, consult your doctor or pharmacist if you are taking any other oral nasal decongestants or stimulants. Always follow the dosage instructions carefully and do not exceed the recommended amount.

If you experience nervousness, dizziness, or sleeplessness, or if your symptoms do not improve within 7 days or are accompanied by a fever, stop using the product and contact your doctor. If your cough lasts more than 7 days, returns, or is accompanied by a fever, rash, or persistent headache, seek medical advice, as these may indicate a more serious condition. In case of an overdose, get medical help immediately or contact a Poison Control Center at 1-800-222-1222.

Overdose

If you suspect an overdose, it’s crucial to seek medical help immediately. You can contact a Poison Control Center at 1-800-222-1222 for guidance. Signs of an overdose can vary, but they may include unusual drowsiness, confusion, or difficulty breathing.

Don’t wait to see if symptoms improve; getting prompt assistance can be vital. Always prioritize your safety and the safety of others by acting quickly in these situations.

Pregnancy Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using this medication. They can provide guidance on whether it’s safe for you and your baby. Always prioritize your health and the health of your child by seeking expert advice.

Lactation Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using any medication. This ensures that you understand any potential risks and can make informed decisions about your health and the health of your baby. Always prioritize open communication with your doctor regarding your breastfeeding journey.

Pediatric Use

This product is specifically designed for adults and should not be used in children under 12 years of age. If you have a child who is younger than 12, it is important to avoid using this medication for their safety. Always consult with a healthcare professional if you have questions about appropriate treatments for your child.

Geriatric Use

If you are an older adult or caring for one, it's important to know that this medication is not suitable for children under 12 years old. For adults and teens aged 12 and older, the recommended dosage is 10 mL every 4 hours, but you should not take more than 6 doses in a 24-hour period.

Before using this product, consult with a doctor if you have any heart conditions, diabetes, high blood pressure, thyroid issues, a chronic cough, or difficulty urinating due to an enlarged prostate. Additionally, if you experience nervousness, dizziness, or trouble sleeping, or if your symptoms do not improve within 7 days, you should stop using the medication and seek medical advice. It's also important to contact a doctor if your cough lasts more than a week, returns, or is accompanied by fever, rash, or a persistent headache.

Renal Impairment

If you have kidney problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or safety considerations for your condition. This means that there are no tailored guidelines for how this medication may affect you if your kidneys are not functioning properly.

Always consult your healthcare provider for personalized advice and to ensure that any medication you take is safe and appropriate for your kidney health. They can help monitor your condition and make any necessary adjustments to your treatment plan.

Hepatic Impairment

If you have liver problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or precautions for your condition. This means that there are no tailored guidelines for how this medication may affect you if you have hepatic impairment (liver issues).

Before starting any new medication, including this one, you should discuss your liver health with your healthcare provider. They can help determine the best approach for your treatment and ensure your safety.

Drug Interactions

It's important to be cautious when taking this medication, especially if you are currently using a prescription monoamine oxidase inhibitor (MAOI), which is a type of drug often prescribed for depression, certain psychiatric conditions, or Parkinson’s disease. You should not take this medication if you are on an MAOI or for two weeks after stopping it. If you're unsure whether your current prescription includes an MAOI, please consult your doctor or pharmacist.

Additionally, if you are taking any other oral nasal decongestants or stimulants, it's wise to check with your healthcare provider before using this product. Discussing all your medications and any lab tests with your healthcare provider helps ensure your safety and the effectiveness of your treatment.

Storage and Handling

To ensure the best performance of your product, store it at room temperature, specifically between 20-25°C (68-77°F). It's important not to refrigerate the product, as this could affect its effectiveness.

When handling the product, make sure to do so in a clean environment to maintain its integrity. Always follow any additional safety instructions provided to ensure safe and effective use.

Additional Information

You should take this medication orally, with the recommended dose being 10 mL every 4 hours for adults and children aged 12 years and older. If your child is under 12 years old, do not use this medication.

If you are pregnant or breastfeeding, it's important to consult a healthcare professional before using this product. Always keep it out of reach of children. In case of an overdose, seek medical help immediately or contact a Poison Control Center at 1-800-222-1222.

FAQ

What is Adult Tussin Multi-Symptom Cold CF used for?

Adult Tussin Multi-Symptom Cold CF helps loosen phlegm (mucus) and thin bronchial secretions to drain bronchial tubes, temporarily relieving symptoms of nasal congestion and cough due to minor throat and bronchial irritation.

Who can use Adult Tussin Multi-Symptom Cold CF?

This product is intended for adults and children aged 12 years and over. It is not recommended for children under 12 years of age.

What are the active ingredients in Adult Tussin Multi-Symptom Cold CF?

It contains Dextromethorphan HBr (20 mg) as a cough suppressant, Guaifenesin (200 mg) as an expectorant, and Phenylephrine HCl (10 mg) as a nasal decongestant.

How should I take Adult Tussin Multi-Symptom Cold CF?

You should take 10 mL every 4 hours, not exceeding 6 doses in a 24-hour period. Use the dosing cup provided for accurate measurement.

Are there any contraindications for using this product?

Do not use Adult Tussin Multi-Symptom Cold CF if you are currently taking a prescription monoamine oxidase inhibitor (MAOI) or have taken one within the last 2 weeks.

What should I do if I experience side effects?

Stop using the product and consult a doctor if you experience nervousness, dizziness, sleeplessness, or if symptoms do not improve within 7 days or are accompanied by fever.

Can I use Adult Tussin Multi-Symptom Cold CF if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, you should ask a health professional before using this product.

How should I store Adult Tussin Multi-Symptom Cold CF?

Store the product between 20-25°C (68-77°F) and do not refrigerate.

Packaging Info

Below are the non-prescription pack sizes of Tussin Cf (dextromethorphan hbr, guaifenesin, phenylephrine hcl). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Tussin Cf.
Details

Drug Information (PDF)

This file contains official product information for Tussin Cf, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

This formulation contains Dextromethorphan HBr at a dosage of 20 mg, serving as a cough suppressant. It also includes Guaifenesin at 200 mg, functioning as an expectorant, and Phenylephrine HCl at 10 mg, acting as a nasal decongestant. The product is intended for individuals aged 12 years and older. A dosing cup is provided with the product. It is designed to be non-drowsy and is alcohol-free. The packaging is tamper-evident; do not use if the carton is opened or if the printed safety seal around the bottle or under the cap is broken or missing. Users are advised to retain the outer carton for complete warnings and product information.

Uses and Indications

This drug is indicated for the relief of symptoms associated with colds, specifically nasal congestion and cough due to minor throat and bronchial irritation. It aids in loosening phlegm (mucus) and thinning bronchial secretions, facilitating drainage of the bronchial tubes.

There are no teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

The recommended dosage for adults and children aged 12 years and older is 10 mL administered every 4 hours as needed. It is imperative that no more than 6 doses are taken within a 24-hour period.

Healthcare professionals should instruct patients to measure the dosage exclusively with the dosing cup provided with the product, as the use of any other dosing device is not advised. The dosing cup should be kept with the product to ensure proper measurement.

This product is not intended for use in children under 12 years of age; therefore, it should not be administered to this population.

Contraindications

Use of this product is contraindicated in patients currently taking a prescription monoamine oxidase inhibitor (MAOI) or within 2 weeks of discontinuing an MAOI. MAOIs are commonly prescribed for depression, psychiatric or emotional conditions, or Parkinson’s disease. Patients should consult a healthcare professional if uncertain whether their prescription includes an MAOI.

Warnings and Precautions

The use of this product is contraindicated in individuals currently taking prescription monoamine oxidase inhibitors (MAOIs), which are medications prescribed for depression, psychiatric or emotional conditions, or Parkinson’s disease. Additionally, it should not be used for a period of two weeks following the cessation of an MAOI. Healthcare professionals should advise patients to consult with a doctor or pharmacist if they are uncertain whether their prescription medication contains an MAOI.

Prior to use, it is essential for patients to seek medical advice if they have any of the following conditions: heart disease, diabetes, high blood pressure, thyroid disease, a chronic cough (such as that associated with smoking, asthma, chronic bronchitis, or emphysema), a cough that produces excessive phlegm, or difficulty urinating due to an enlarged prostate gland.

Patients should also consult a doctor or pharmacist before using this product if they are currently taking any other oral nasal decongestants or stimulants, as interactions may occur.

During the use of this product, it is critical that patients adhere strictly to the recommended dosage and not exceed the directed amount.

Patients should discontinue use and seek medical attention if they experience nervousness, dizziness, or sleeplessness. Additionally, if symptoms do not improve within seven days or are accompanied by fever, or if a cough persists for more than seven days, recurs, or is associated with fever, rash, or a persistent headache, medical advice should be sought immediately, as these may indicate a serious underlying condition.

In the event of an overdose, it is imperative to obtain medical assistance or contact a Poison Control Center at 1-800-222-1222 without delay.

Side Effects

Patients may experience a range of adverse reactions while using this product. Serious adverse reactions warrant immediate medical attention and include symptoms such as nervousness, dizziness, or sleeplessness. Patients should discontinue use and consult a healthcare professional if these symptoms occur, if symptoms do not improve within 7 days, or if they are accompanied by fever. Additionally, a cough that persists for more than 7 days, recurs, or is associated with fever, rash, or a persistent headache may indicate a serious underlying condition and should be evaluated by a healthcare provider.

Common adverse reactions may include those related to pre-existing health conditions. Patients with heart disease, diabetes, high blood pressure, thyroid disease, or chronic respiratory conditions such as asthma, chronic bronchitis, or emphysema should seek medical advice before using this product. Furthermore, individuals experiencing a cough that produces excessive phlegm or those with urinary difficulties due to an enlarged prostate gland should also consult a healthcare professional prior to use.

It is important to note that this product should not be used in conjunction with prescription monoamine oxidase inhibitors (MAOIs), which are medications prescribed for depression, psychiatric or emotional conditions, or Parkinson’s disease. Patients should refrain from using this product while taking an MAOI or for 2 weeks following the cessation of an MAOI. If there is uncertainty regarding the presence of an MAOI in a prescription medication, patients are advised to consult a doctor or pharmacist before proceeding with this product.

Drug Interactions

The concomitant use of this product with prescription monoamine oxidase inhibitors (MAOIs) is contraindicated. Patients should not take this product while on MAOIs, which are commonly prescribed for depression, psychiatric or emotional conditions, or Parkinson’s disease, and for a period of two weeks following the discontinuation of an MAOI. If there is uncertainty regarding the presence of an MAOI in a current prescription, it is advised to consult a healthcare professional, such as a doctor or pharmacist, prior to using this product.

Additionally, it is recommended that patients seek guidance from a healthcare professional before using this product in conjunction with any other oral nasal decongestants or stimulants. This precaution is essential to avoid potential adverse interactions.

Packaging & NDC

Below are the non-prescription pack sizes of Tussin Cf (dextromethorphan hbr, guaifenesin, phenylephrine hcl). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Tussin Cf.
Details

Pediatric Use

This product is not intended for use in pediatric patients under 12 years of age. The safety and efficacy of this product have not been established in children younger than 12. Therefore, it is contraindicated for use in this age group.

Geriatric Use

Elderly patients may require special consideration when using this product, which is not intended for use in children under 12 years of age. For adults and children aged 12 years and older, the recommended dosage is 10 mL every 4 hours, with a maximum of 6 doses in any 24-hour period.

It is important for healthcare providers to assess the overall health status of geriatric patients prior to prescribing this medication. Patients with a history of heart disease, diabetes, high blood pressure, thyroid disease, chronic cough, or urinary difficulties due to an enlarged prostate gland should consult a physician before use.

Monitoring for adverse effects is crucial in elderly patients. If symptoms such as nervousness, dizziness, or sleeplessness occur, or if symptoms do not improve within 7 days, patients should discontinue use and seek medical advice. Additionally, if a cough persists for more than 7 days, recurs, or is accompanied by fever, rash, or a persistent headache, medical consultation is advised. These precautions are essential to ensure the safety and efficacy of the treatment in the geriatric population.

Pregnancy

Pregnant patients and those who are breastfeeding should consult a healthcare professional prior to using this medication. The potential risks and benefits must be carefully weighed, as the effects on fetal outcomes and lactation are not fully established. It is essential for women of childbearing potential to seek medical advice to ensure the safety of both the mother and the developing fetus or nursing infant.

Lactation

Lactating mothers are advised to consult a health professional prior to using this medication. There is currently no available data regarding the excretion of this medication in human breast milk or its effects on breastfed infants. Therefore, caution is recommended when administering this medication to lactating mothers.

Renal Impairment

Patients with renal impairment have not been specifically studied in relation to dosage adjustments, special monitoring, or safety considerations for this medication. As such, there is no available information regarding the use of this drug in individuals with reduced kidney function. Healthcare professionals should exercise caution and consider the lack of data when prescribing this medication to patients with renal impairment.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the prescribing information.

Overdosage

In the event of an overdose, it is imperative to seek immediate medical assistance or contact a Poison Control Center at 1-800-222-122. Prompt action is crucial to ensure the safety and well-being of the patient.

Healthcare professionals should be aware that symptoms of overdose may vary depending on the substance involved and the individual’s health status. Monitoring the patient closely for any signs of adverse reactions is essential.

Management of an overdose typically involves supportive care and symptomatic treatment. The specific interventions may depend on the nature of the overdose and the clinical presentation of the patient. It is advisable to follow established protocols and guidelines for the management of overdose cases to ensure optimal outcomes.

Nonclinical Toxicology

If pregnant or breastfeeding, it is advised to consult a health professional prior to use. No specific non-teratogenic effects have been identified in the available data. Additionally, there are no detailed findings regarding nonclinical toxicology or animal pharmacology and toxicology provided in the current information.

Postmarketing Experience

No postmarketing experience details are available in the insert text.

Patient Counseling

Healthcare providers should advise patients to seek immediate medical help or contact a Poison Control Center at 1-800-222-1222 in the event of an overdose. It is crucial to inform patients that this product should not be used concurrently with prescription monoamine oxidase inhibitors (MAOIs), which are medications prescribed for depression, psychiatric or emotional conditions, or Parkinson’s disease. Patients should also be cautioned against using this product for two weeks after discontinuing an MAOI. If patients are uncertain whether their prescription includes an MAOI, they should be encouraged to consult their doctor or pharmacist.

Patients should be instructed to discontinue use and consult a doctor if they experience nervousness, dizziness, or sleeplessness. Additionally, they should be advised to stop using the product and seek medical advice if their symptoms do not improve within seven days or if they are accompanied by fever. It is important to inform patients that they should also stop use and consult a doctor if their cough persists for more than seven days, recurs, or is accompanied by fever, rash, or a persistent headache, as these may indicate a serious condition.

While using this product, patients must be reminded not to exceed the recommended dosage. Healthcare providers should encourage patients to consult a doctor before use if they have any of the following conditions: heart disease, diabetes, high blood pressure, thyroid disease, or a chronic cough associated with smoking, asthma, chronic bronchitis, or emphysema. Patients should also be advised to seek medical advice if they have a cough that produces excessive phlegm or if they experience difficulty urinating due to an enlarged prostate gland. Lastly, it is essential to recommend that patients consult a doctor or pharmacist before using this product if they are taking any other oral nasal decongestants or stimulants.

Storage and Handling

The product is supplied in various package configurations, with specific NDC numbers available for identification. It is essential to store the product at a temperature range of 20-25°C (68-77°F). Refrigeration is not recommended, as it may compromise the integrity of the product. Proper handling and storage conditions must be adhered to in order to maintain product efficacy and safety.

Additional Clinical Information

The medication is administered orally, with a recommended dosage of 10 mL every 4 hours for adults and children aged 12 years and older. It is contraindicated for use in children under 12 years. Clinicians should advise patients to consult a health professional if they are pregnant or breastfeeding. Additionally, it is crucial to keep the medication out of reach of children. In the event of an overdose, patients should seek medical assistance or contact a Poison Control Center immediately at 1-800-222-1222.

No further information is available regarding laboratory tests, abuse potential, or postmarketing experiences.

Drug Information (PDF)

This file contains official product information for Tussin Cf, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Tussin Cf, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

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Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.