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Mucus Relief Dm

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Active ingredients
  • Guaifenesin 400 mg
  • Dextromethorphan Hydrobromide 20 mg
Other brand names
Drug classes
Expectorant, Sigma-1 Agonist, Uncompetitive N-methyl-D-aspartate Receptor Antagonist
Dosage form
Capsule, Liquid Filled
Route
Oral
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2021
Label revision date
January 16, 2026
Drug Information (PDF)
Prescribing information, PDF file
Active ingredients
  • Guaifenesin 400 mg
  • Dextromethorphan Hydrobromide 20 mg
Other brand names
Drug classes
Expectorant, Sigma-1 Agonist, Uncompetitive N-methyl-D-aspartate Receptor Antagonist
Dosage form
Capsule, Liquid Filled
Route
Oral
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2021
Label revision date
January 16, 2026
Manufacturer
Walgreens
Registration number
M012
NDC root
0363-9013
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info
Packaging & NDC Codes

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

Mucus Relief DM is a medication designed to help you manage cough and mucus buildup. It contains two active ingredients: guaifenesin (an expectorant) and dextromethorphan HBr (a cough suppressant). Guaifenesin works by loosening phlegm and thinning bronchial secretions, making your coughs more productive. Meanwhile, dextromethorphan helps control your cough, providing relief when you need it most.

This medication is available in the form of softgels that dissolve quickly, making it easy to take. Mucus Relief DM is particularly useful for those experiencing congestion and coughing due to colds or other respiratory conditions.

Uses

This medication is designed to help you breathe easier by loosening phlegm (a thick mucus) in your airways. By doing so, it makes your coughs more productive, allowing you to clear out mucus more effectively. This can be particularly helpful if you're dealing with respiratory issues that involve congestion.

You can expect this treatment to assist in thinning bronchial secretions, which can improve your overall comfort and respiratory function.

Dosage and Administration

If you are an adult or a child aged 12 years and older, you should take one softgel with a full glass of water every four hours as long as your symptoms continue. It's important not to take more than six doses in a 24-hour period to ensure your safety.

For children under 12 years of age, this medication is not recommended, so please avoid using it for younger individuals. Always remember to stay hydrated by drinking a full glass of water with each dose.

What to Avoid

You should avoid using this product if you are currently taking a prescription monoamine oxidase inhibitor (MAOI), which is a type of medication used for depression, psychiatric, or emotional conditions, or Parkinson's disease. Additionally, do not use this product for at least 2 weeks after stopping an MAOI. If you're unsure whether your prescription includes an MAOI, please consult your doctor or pharmacist.

While using this product, it's important not to exceed the recommended dosage and to limit your use to no more than 7 days. This helps prevent potential misuse or dependence (a condition where your body becomes reliant on a substance). Always prioritize your safety and well-being by following these guidelines.

Side Effects

You should be aware of some important side effects and warnings associated with this medication. Do not use it if you are currently taking a prescription monoamine oxidase inhibitor (MAOI), which is a type of medication for depression or certain other conditions, or for two weeks after stopping an MAOI. If you are unsure whether your medication contains an MAOI, consult your doctor or pharmacist.

Before using this product, talk to your doctor if you have a cough with excessive mucus or a persistent cough due to smoking, asthma, chronic bronchitis, or emphysema. You should stop using the medication and seek medical advice if your cough lasts more than seven days, comes back, or is accompanied by fever, rash, or a persistent headache, as these may indicate a more serious issue. If you are pregnant or breastfeeding, consult a healthcare professional before use. In case of an accidental overdose, seek medical help immediately or contact a Poison Control Center.

Warnings and Precautions

You should not use this product if you are currently taking a prescription monoamine oxidase inhibitor (MAOI), which is a type of medication used for depression or certain other conditions, or if you have stopped taking an MAOI within the last two weeks. If you're unsure whether your medication contains an MAOI, please consult your doctor or pharmacist before using this product.

Before using this product, it's important to talk to your doctor if you have a cough with a lot of mucus, or if you have a chronic cough due to smoking, asthma, chronic bronchitis, or emphysema. Always follow the recommended dosage and do not use it for more than 7 days. If you accidentally take too much, seek medical help or contact a Poison Control Center immediately.

If your cough lasts longer than 7 days, comes back, or is accompanied by fever, rash, or a persistent headache, stop using the product and call your doctor, as these may be signs of a more serious condition.

Overdose

If you suspect an accidental overdose, it’s important to seek medical help immediately or contact a Poison Control Center. Signs of an overdose can vary, but they may include unusual symptoms that are not typical for you.

Don’t wait for symptoms to worsen; getting prompt assistance can be crucial. Always prioritize your health and safety by reaching out for help as soon as you have concerns about an overdose.

Pregnancy Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using this medication. They can provide guidance on whether it’s safe for you and your baby. Always prioritize your health and the health of your child by seeking expert advice.

Lactation Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using any medication. This ensures that you understand any potential risks and can make informed decisions about your health and the health of your baby. Always prioritize open communication with your doctor regarding your breastfeeding journey.

Pediatric Use

It's important to be cautious when considering this medication for children. If your child is under 12 years old, you should not use this product. For those aged 12 and older, the recommended dosage is one softgel every four hours, taken with a full glass of water, as long as symptoms continue. However, do not exceed six doses in a 24-hour period.

Always keep this medication out of reach of children. If an accidental overdose occurs, seek medical help or contact a Poison Control Center immediately. Your child's safety is the top priority, so please follow these guidelines carefully.

Geriatric Use

While there is no specific information available about the use of this medication in older adults, it’s important to approach any new treatment with caution. If you or a loved one is an older adult, it’s always wise to discuss any medications with a healthcare provider, especially considering factors like changes in kidney function (renal impairment) and cognitive abilities that can occur with age.

Since there are no dosage adjustments or special precautions outlined for elderly patients, your healthcare provider can help determine the best approach based on individual health needs and conditions. Always prioritize open communication with your doctor to ensure safe and effective use of any medication.

Renal Impairment

If you have kidney problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or safety considerations for your condition. This means that there are no tailored guidelines for how this medication may affect you if you have renal impairment (kidney issues).

Always consult your healthcare provider for personalized advice and to ensure that any medication you take is safe and appropriate for your health situation. They can help monitor your kidney function and make any necessary adjustments to your treatment plan.

Hepatic Impairment

If you have liver problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or precautions for your condition. This means that there are no tailored guidelines for how this medication should be used if you have hepatic impairment (liver issues).

Always consult your healthcare provider for personalized advice and to ensure that any medication you take is safe and appropriate for your liver health. They can help determine the best course of action based on your individual situation.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you. Always share your complete list of medications and any recent lab tests to avoid any potential issues. Your health and safety should always come first.

Storage and Handling

To ensure the best performance of your product, store it at a temperature of 25°C (77°F). It can safely handle brief temperature changes between 15°C and 30°C (59°F - 86°F). Make sure to keep it in a dry location and avoid exposing it to heat, as this can affect its quality and effectiveness.

When handling the product, always do so with clean hands or gloves to maintain a sterile environment (a clean area free from germs). Following these guidelines will help you use the product safely and effectively.

Additional Information

You should take this medication orally, with one softgel every four hours as long as your symptoms continue. Make sure to drink a full glass of water with each dose, and do not exceed six doses in a 24-hour period. If you are pregnant or breastfeeding, consult a healthcare professional before using this product.

It's important to keep this medication out of reach of children. In case of an accidental overdose, seek medical help or contact a Poison Control Center immediately. If you experience any side effects, you can report them by calling 1-888-333-9792.

FAQ

What is Mucus Relief DM?

Mucus Relief DM is a medication that contains GUAIFENESIN 400 mg (an expectorant) and DEXTROMETHORPHAN HBr 20 mg (a cough suppressant) to help relieve cough and loosen mucus.

How does Mucus Relief DM work?

It helps loosen phlegm (mucus) and thins bronchial secretions, making coughs more productive while controlling cough.

Who can take Mucus Relief DM?

Adults and children 12 years of age and older can take it, but it should not be used by children under 12 years of age.

What is the recommended dosage for adults and children 12 years and older?

Take 1 softgel every 4 hours with a full glass of water while symptoms persist, and do not exceed 6 doses in 24 hours.

Are there any contraindications for Mucus Relief DM?

Do not use if you are taking a prescription monoamine oxidase inhibitor (MAOI) or have taken one within the last 2 weeks.

What should I do if my cough lasts more than 7 days?

Stop use and ask a doctor if your cough lasts for more than 7 days, recurs, or is accompanied by fever, rash, or persistent headache.

Can I use Mucus Relief DM if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, ask a health professional before use.

What should I do in case of accidental overdose?

Get medical help or contact a Poison Control Center right away in case of accidental overdose.

How should I store Mucus Relief DM?

Store at 25°C (77°F) with excursions between 15° - 30°C (59° - 86°F) in a dry place and avoid exposure to heat.

Packaging Info

Below are the non-prescription pack sizes of Mucus Relief Dm (guaifenesin and dextromethorphan hydrobromide). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Mucus Relief Dm.
Details

Drug Information (PDF)

This file contains official product information for Mucus Relief Dm, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the drug.

Uses and Indications

This drug is indicated for the facilitation of mucus clearance in patients with respiratory conditions. It helps to loosen phlegm and thins bronchial secretions, thereby enhancing the productivity of coughs.

There are no teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

Adults and children 12 years of age and older are instructed to take one softgel every four hours while symptoms persist, accompanied by a full glass of water. It is imperative not to exceed six doses within a 24-hour period.

For children under 12 years of age, the use of this medication is not recommended.

Contraindications

Use of this product is contraindicated in patients currently taking a prescription monoamine oxidase inhibitor (MAOI) for depression, psychiatric or emotional conditions, or Parkinson's disease, and for a period of 2 weeks following the discontinuation of an MAOI. Patients should consult a healthcare professional if uncertain whether their prescription medication contains an MAOI.

Additionally, the product should not be used in excess of the recommended dosage or for a duration exceeding 7 days.

Warnings and Precautions

The use of this product is contraindicated in individuals currently taking a prescription monoamine oxidase inhibitor (MAOI), which includes certain medications prescribed for depression, psychiatric or emotional conditions, or Parkinson's disease. Additionally, it should not be used for a period of two weeks following the cessation of an MAOI. Healthcare professionals should advise patients to consult with a doctor or pharmacist if there is uncertainty regarding the presence of an MAOI in their prescription medications.

General precautions should be observed prior to the use of this product. Patients should be advised to seek medical consultation if they experience a cough accompanied by excessive phlegm (mucus) or if they have a persistent or chronic cough, particularly in cases related to smoking, asthma, chronic bronchitis, or emphysema. It is imperative that patients adhere to the recommended dosage and refrain from using the product for more than seven days.

In the event of an accidental overdose, immediate medical assistance should be sought, or the Poison Control Center should be contacted without delay.

Patients are instructed to discontinue use and consult a healthcare provider if their cough persists for more than seven days, recurs, or is accompanied by symptoms such as fever, rash, or a persistent headache, as these may indicate a serious underlying condition.

Side Effects

Patients should be aware of the following adverse reactions associated with the use of this product.

Serious adverse reactions may occur, particularly in patients who are currently taking or have recently discontinued a prescription monoamine oxidase inhibitor (MAOI). The use of this product is contraindicated in such cases, and patients are advised to consult a healthcare professional if they are uncertain whether their prescription medication contains an MAOI.

Common adverse reactions include the need for caution in patients with specific conditions. Individuals experiencing a cough accompanied by excessive phlegm, or those with a persistent or chronic cough due to smoking, asthma, chronic bronchitis, or emphysema should seek medical advice before using this product.

Patients are also advised to discontinue use and consult a healthcare provider if their cough persists for more than 7 days, recurs, or is accompanied by additional symptoms such as fever, rash, or a persistent headache, as these may indicate a serious underlying condition.

Additional considerations include the need for pregnant or breastfeeding individuals to consult a health professional prior to use. In the event of an accidental overdose, it is crucial to seek immediate medical assistance or contact a Poison Control Center.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there are no known interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are necessary at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Mucus Relief Dm (guaifenesin and dextromethorphan hydrobromide). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Mucus Relief Dm.
Details

Pediatric Use

Pediatric patients under 12 years of age should not use this medication. For adolescents aged 12 years and older, the recommended dosage is 1 softgel every 4 hours with a full glass of water, while symptoms persist. The maximum allowable dosage is 6 softgels in a 24-hour period.

It is essential to keep this medication out of reach of children. In the event of an accidental overdose, immediate medical assistance should be sought, or contact a Poison Control Center without delay.

Geriatric Use

Elderly patients may not have specific information regarding the use of this medication, including dosage adjustments, safety concerns, or special precautions. Therefore, healthcare providers should exercise caution when prescribing this medication to geriatric patients. It is advisable to monitor these patients closely for any adverse effects or changes in therapeutic response, given the lack of targeted data for this population.

Pregnancy

Pregnant patients and those who are breastfeeding should consult a healthcare professional prior to using this medication. It is important to assess the potential risks and benefits, as well as any available data regarding fetal outcomes and lactation. Healthcare providers can offer guidance tailored to individual circumstances, ensuring the safety of both the patient and the developing fetus or nursing infant.

Lactation

Lactating mothers are advised to consult a healthcare professional prior to using this medication. There is no specific data available regarding the excretion of this medication in breast milk or its effects on breastfed infants. Therefore, caution is recommended when administering this medication to lactating individuals.

Renal Impairment

Patients with renal impairment have no specific information regarding dosage adjustments, special monitoring, or safety considerations provided in the drug insert. Therefore, healthcare professionals should exercise caution when prescribing this medication to individuals with reduced kidney function, as the lack of data necessitates careful clinical judgment.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to this medication. Consequently, there are no dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the prescribing information.

Overdosage

In the event of an accidental overdose, it is imperative to seek immediate medical assistance or contact a Poison Control Center without delay. Prompt action is crucial to mitigate potential adverse effects associated with overdosage.

Healthcare professionals should be aware that symptoms of overdose may vary depending on the specific substance involved. Therefore, a thorough assessment of the patient's condition is essential. Management procedures may include supportive care and symptomatic treatment, tailored to the individual patient's needs.

It is recommended that healthcare providers remain vigilant and prepared to implement appropriate interventions based on the clinical presentation of the patient following an overdose.

Nonclinical Toxicology

If pregnant or breastfeeding, it is advised to consult a health professional prior to use. No specific non-teratogenic effects have been identified in the available data. Additionally, there are no detailed findings regarding nonclinical toxicology or animal pharmacology and toxicology provided in the current information.

Postmarketing Experience

Postmarketing experience has included the collection of voluntary reports and data from surveillance programs regarding side effects associated with the use of the product. Healthcare professionals and patients are encouraged to report any adverse events to the designated contact number, 1-888-333-9792. This information contributes to the ongoing assessment of the product's safety profile.

Patient Counseling

Healthcare providers should advise patients to seek immediate medical assistance or contact a Poison Control Center in the event of an accidental overdose. It is crucial to inform patients that they should not take this product if they are currently using a prescription monoamine oxidase inhibitor (MAOI) or have stopped taking an MAOI within the past two weeks. Patients who are uncertain whether their prescription medication contains an MAOI should be encouraged to consult with their doctor or pharmacist prior to using this product.

Patients should be instructed to discontinue use and consult a healthcare professional if their cough persists for more than 7 days, recurs, or is accompanied by symptoms such as fever, rash, or a persistent headache, as these may indicate a serious underlying condition. It is important to emphasize that patients must not exceed the recommended dosage and should not use the product for more than 7 days.

Additionally, healthcare providers should recommend that patients consult with their doctor before using this product if they have a cough that is accompanied by excessive phlegm (mucus) or if they have a persistent or chronic cough, such as that associated with smoking, asthma, chronic bronchitis, or emphysema.

Storage and Handling

The product is supplied in a configuration that includes specific NDC numbers, which should be referenced for accurate identification. It is essential to store the product at a controlled room temperature of 25°C (77°F), with permissible excursions between 15°C and 30°C (59°F and 86°F).

The product must be kept in a dry environment, ensuring that it is not exposed to heat or moisture, as these conditions may compromise its integrity and efficacy. Proper handling and storage are crucial to maintain the quality of the product throughout its shelf life.

Additional Clinical Information

Patients should take the medication orally, with one softgel every four hours as needed, ensuring not to exceed six doses within a 24-hour period. It is advised to take the softgel with a full glass of water while symptoms persist.

Clinicians should counsel patients to consult a health professional if they are pregnant or breastfeeding before use. Additionally, it is crucial to keep the medication out of reach of children. In the event of an accidental overdose, patients should seek medical assistance or contact a Poison Control Center immediately. For reporting side effects, patients can reach out to 1-888-333-9792.

Drug Information (PDF)

This file contains official product information for Mucus Relief Dm, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Mucus Relief Dm, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

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Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.