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Doracide
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- Active ingredient
- Doramectin 5 mg/1 mL
- Other brand names
- Dosage form
- Solution
- Route
- Topical
- Prescription status
- Animal
- Pregnancy
- See Pregnancy Use Section
- Lactation
- See Lactation Use Section
- Marketed in the U.S.
- Since 2025
- Label revision date
- April 24, 2025
- Veterinary Document
- Prescribing information, PDF file
- Active ingredient
- Doramectin 5 mg/1 mL
- Other brand names
- Dosage form
- Solution
- Route
- Topical
- Prescription status
- Animal
- CSA schedule
- Not a scheduled drug
- Pregnancy
- See Pregnancy Use Section
- Lactation
- See Lactation Use Section
- Marketed in the U.S.
- Since 2025
- Label revision date
- April 24, 2025
- Manufacturer
- MWI/VetOne
- Registration number
- ANADA200636
- NDC root
- 86136-124
- Veterinary Document
- Prescribing information, PDF file
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Drug Overview
Doracide™ is a topical solution containing doramectin, an antiparasitic medication specifically designed for cattle. This ready-to-use solution is applied as a pour-on treatment, delivering a dosage of 500 micrograms per kilogram of body weight. It works by targeting and eliminating various parasites that can affect cattle, helping to maintain their health and well-being.
The solution is clear and light blue, with a concentration of 0.5% doramectin (5 mg/mL), making it easy to administer. By applying Doracide™ topically, you can effectively protect your cattle from parasitic infestations.
Uses
It seems that the information provided does not include specific details about the species or the conditions and diseases that the drug treats or prevents. Without this information, I cannot provide a clear and informative summary for you. If you have more specific details or another list of uses, please share that, and I would be happy to help rewrite it for you!
Dosage and Administration
To use Doracide Pour-On solution for your cattle, you need to apply it topically, which means putting it directly on the skin. The recommended dosage is 500 micrograms (mcg) of doramectin per kilogram (kg) of the animal's body weight, or 227 mcg per pound (lb). Each milliliter (mL) of the solution contains 5 mg of doramectin, which is enough to treat cattle weighing up to 22 lb (10 kg).
When applying the solution, do so in a narrow strip along the mid-line of the back, between the withers (the area just above the shoulder) and the tailhead (the base of the tail). You can use a 5-liter (L) backpack applicator for this process. First, replace the shipping cap on the backpack with the draw-off cap and secure it tightly. Then, thread the draw-off tubing through the anti-kink spring and attach it to the draw-off cap. Invert the backpack and set the dose to the maximum of 50 mL. Prime the applicator to check for leaks, and then set the required dose before administering it to your cattle. After use, make sure to clean the applicator according to the manufacturer's instructions and securely replace the cap on the backpack.
What to Avoid
It's important to follow specific guidelines when using this product to ensure safety and effectiveness. You should not use it in female dairy cattle that are 20 months or older, or in calves intended for veal production. Additionally, avoid using this product in other animal species, as it can cause severe adverse reactions, including fatalities in dogs.
This product is classified as a restricted drug in California, so use it only as directed. Be sure to administer the full dose based on the animal's current body weight, as underdosing can lead to ineffective treatment and may contribute to parasite resistance. Do not give the product orally or through injections, and avoid applying it to dirty skin. Remember to wash your hands after handling the product and refrain from eating or smoking during this time. After treatment, keep cattle away from lakes, streams, or ponds for at least six hours, and ensure that you do not contaminate water sources with the product or its containers.
Side Effects
Using Doracide Pour-On solution for cattle can lead to some serious side effects, especially if not used correctly. It's important to note that this product is flammable, so keep it away from heat and open flames. It should not be applied to humans, as it may irritate the skin and eyes. If you accidentally come into contact with it, wash the area with soap and water, and if it gets in your eyes, flush them with water and seek medical help.
Additionally, using this product on other animal species can result in severe reactions, including fatalities in dogs. When treating cattle for Hypoderma larvae (cattle grubs), there is a risk of serious host-parasite reactions, which can also lead to fatalities. For example, killing certain types of grubs in specific areas can cause bloat or even staggering and paralysis. Always handle this product with care to avoid these potential risks.
Warnings and Precautions
It’s important to handle Doracide Pour-On solution for cattle with care. This product is flammable, so keep it away from heat, sparks, open flames, and other ignition sources. Remember, it is not meant for human use, so always keep it out of reach of children.
When applying this solution, be cautious as it can irritate your skin and eyes. Make sure to wear protective clothing, including a long-sleeved shirt, gloves, and waterproof boots. After use, wash your protective gear thoroughly. If you accidentally get the solution on your skin, wash the area with soap and water right away. If it gets in your eyes, rinse them with water immediately and seek medical help.
Overdose
If you suspect an overdose, it's important to stay calm and take immediate action. While there is no specific information available about the signs of overdose for this medication, general symptoms can include unusual drowsiness, confusion, or difficulty breathing. If you notice any of these signs, or if you are unsure, seek medical help right away.
In case of an overdose, contact your local emergency services or go to the nearest hospital. It's always better to be safe and get checked by a healthcare professional if you have any concerns about your health.
Pregnancy Use
If you are pregnant or planning to become pregnant, it's important to know that Doracide Pour-On solution has been shown to have no negative effects on breeding performance in cattle during critical stages of pregnancy, such as folliculogenesis (the development of eggs), organogenesis (the formation of organs), implantation, and throughout gestation. This was observed even when the solution was given at a dose three times higher than the recommended amount for the injectable form of doramectin.
Additionally, studies indicate that the exposure to doramectin from the pour-on solution is lower than that from the injectable version. Importantly, there are no specific warnings or contraindications regarding the use of Doracide Pour-On in pregnant cattle, suggesting it is considered safe in this context. Always consult with your veterinarian for personalized advice and guidance.
Lactation Use
If you are breastfeeding or planning to breastfeed, it's important to be aware that there is no specific information available regarding the use of this medication during nursing. This means that the effects on breast milk production and the nursing infant are not clearly defined.
As always, it's best to consult with your healthcare provider to discuss any medications you are considering while breastfeeding. They can help you weigh the benefits and risks based on your individual situation.
Pediatric Use
Doracide Pour-On solution is specifically designed for use in cattle and should never be used in children or other animal species, as this can lead to serious adverse reactions. While safety studies have shown that doramectin, the active ingredient, is safe for neonatal calves (young calves) even at doses up to three times the recommended amount, it is important to follow all guidelines carefully.
For your child's safety, remember that this product is not suitable for female dairy cattle that are 20 months old or older, and there is no established withdrawal period for this solution in calves that have not yet started ruminating (digesting food in a specific way). Additionally, do not use this product in calves intended for veal production. Always consult with a veterinarian for appropriate treatments for your animals.
Geriatric Use
When it comes to using this medication in older adults, there is no specific information available about dosage adjustments, safety concerns, or special precautions. This means that if you or a loved one is an older adult considering this medication, it’s important to consult with a healthcare provider. They can help determine the best approach based on individual health needs and any other medications being taken. Always prioritize open communication with your healthcare team to ensure safe and effective treatment.
Renal Impairment
If you have kidney problems, it's important to know that there are no specific guidelines, dosage adjustments, or monitoring requirements mentioned for your condition in the provided information. This means that the standard recommendations for medication use may apply to you without any special considerations. However, always consult your healthcare provider for personalized advice and to ensure your treatment is safe and effective based on your kidney health.
Hepatic Impairment
If you have liver problems, it's important to know that there are no specific guidelines or dosage adjustments mentioned for your condition in the available information. This means that the standard recommendations apply, but you should always consult your healthcare provider for personalized advice. They can help monitor your liver function and determine the best course of action for your treatment.
Make sure to keep your doctor informed about your liver health, as they may need to conduct regular liver function tests (which check how well your liver is working) to ensure your safety while using any medication.
Drug Interactions
It's important to talk to your healthcare provider about any medications you are taking, especially when it comes to dewormers. Before using a dewormer, your provider may recommend conducting fecal examinations or other diagnostic tests to ensure it's the right choice for your situation. After treatment, monitoring its effectiveness is crucial, which can be done through tests like a fecal egg count reduction test. This helps determine if the dewormer is still working effectively, as a decrease in its effectiveness over time may suggest that resistance has developed.
Always keep your healthcare provider informed about your treatment and any tests you undergo. This collaboration is key to ensuring you receive the best care possible.
Storage and Handling
To ensure the best performance of your product, store it in a cool, dry place at temperatures below 25˚C (77˚F). It's important to keep it protected from light to maintain its effectiveness. When you're finished using the product, please dispose of any containers responsibly by placing them in an approved landfill or by incineration. Following these guidelines will help ensure safety and proper handling.
Additional Information
No further information is available.
FAQ
What is Doracide™?
Doracide™ is a topical solution containing 0.5% doramectin, designed as an antiparasitic treatment for cattle.
How should I administer Doracide™?
Apply Doracide™ topically along the mid-line of the back in a narrow strip between the withers and tailhead.
What is the recommended dosage for Doracide™?
The recommended dosage is 500 mcg of doramectin per kg (227 mcg/lb) of body weight, with each mL treating 22 lb (10 kg) of body weight.
What precautions should I take when using Doracide™?
Avoid contact with skin and eyes, and wear protective clothing. Do not use in female dairy cattle over 20 months old or in calves intended for veal.
What should I do if I accidentally contact my skin with Doracide™?
Wash the affected area immediately with soap and water. If there is eye exposure, flush the eyes with water and seek medical attention.
Can Doracide™ be used in other animal species?
No, Doracide™ should not be used in other animal species as it may cause severe adverse reactions, including fatalities in dogs.
What should I do if I underdose with Doracide™?
Ensure each animal receives a complete dose based on current body weight, as underdosing may lead to ineffective treatment and parasite resistance.
How should I store Doracide™?
Store Doracide™ below 25˚C (77˚F) and protect it from light.
What are the potential side effects of using Doracide™?
Doracide™ may irritate human skin and eyes. Additionally, killing certain cattle grubs can lead to undesirable reactions such as bloat or staggering.
Is there a withdrawal period for Doracide™?
A withdrawal period has not been established for this product in preruminating calves.
Packaging Info
The table below lists each NDC Code for Doracide (doramectin) veterinary formulations. Columns show Packaging, Formulation Type, and Active Ingredient Strength.
Details | ||||
|---|---|---|---|---|
| Solution | 5 mg/1 mL | ||
Product details Regulatory status — Marketed All current FDA data sets list this NDC as actively marketed. FDA record dates for this NDC:
Active ingredients
| ||||
Drug Information (PDF)
This PDF provides official product information for Doracide, which is intended for animal use only.
Description
DORACIDE™ (doramectin topical solution) is a ready-to-use, systemically active antiparasitic formulation designed for cattle. This pour-on solution contains 0.5% w/v doramectin, equivalent to 5 mg/mL. The product is presented as a clear, light blue solution. It is formulated to provide a recommended dosage of 500 mcg/kg (227 mcg/lb) of body weight when administered topically at a rate of 1 mL per 22 lb (10 kg) of body weight.
Uses and Indications
This drug is indicated for the treatment and prevention of specified conditions and diseases as determined by healthcare professionals. The specific species and conditions for which this drug is indicated have not been detailed in the provided information.
Healthcare professionals are advised to refer to additional resources or clinical guidelines to ascertain the appropriate usage instructions and targeted patient populations for this drug.
Dosage and Administration
Doracide Pour-On solution is to be administered topically to cattle at a dosage of 500 mcg of doramectin per kg (227 mcg/lb) of body weight. Each milliliter of the solution contains 5 mg of doramectin, which is adequate to treat 22 lb (10 kg) of body weight.
The solution should be applied in a narrow strip along the mid-line of the back, specifically between the withers and the tailhead.
For administration, Doracide Pour-On solution is compatible with applicators supplied in 5-L backpacks. Two applicator systems are available: the Phillips Pour-on Applicator System and the Syrvet Pour-on Applicator System.
Phillips Pour-on Applicator System
Replace the shipping cap on the 5-L backpack with the provided draw-off cap and tighten it firmly.
Thread the draw-off tubing through the anti-kink spring and attach it to the draw-off cap. Secure the spring by screwing it counterclockwise over the tubing and draw-off spigot.
Invert the backpack.
Set the dose to the maximum of 50 mL. Prime the applicator gently while checking for leaks by placing the nozzle into a clean, dry receptacle and fully depressing the lever. Perform 3–4 short strokes to ensure the piston reaches the end of the cylinder, then release the lever completely to fill the cylinder. A small air bubble may appear within the cylinder, which will not affect dosing accuracy.
Set the required dose and administer.
To disconnect the system, position the backpack upright and discharge any residual material from the applicator and draw-off tubing into a separate, clean, dry receptacle.
Adhere to the manufacturer's recommendations for the care and maintenance of the dosing applicator.
Remove the draw-off cap and replace it with the original cap, tightening it firmly.
Syrvet Pour-on Applicator System
Replace the shipping cap on the 5-L backpack with the provided draw-off cap and tighten it firmly.
Thread the draw-off tubing through the anti-kink spring and attach it to the draw-off cap. Secure the spring by screwing it clockwise over the tubing and draw-off spigot.
Invert the backpack.
Set the dose at the maximum of 50 mL by unscrewing the adjuster at the base of the handle. Prime the applicator gently while checking for leaks by pointing the nozzle into a clean, dry receptacle and pumping the lever back and forth to expel air from the system. When the barrel fills completely after each priming stroke, set the dose.
To set the dose, align the middle of the blue plunger ring with the chosen mark on the barrel using the handle. Tighten the adjuster screw against the handle and secure the dose with the adjuster screw locknut.
Administer each dose by fully depressing the handle, allowing the plunger to travel its entire set length. Release the handle, and the applicator will automatically refill.
To disconnect the system, position the backpack upright and discharge any residual material from the applicator and draw-off tubing into a separate, dry receptacle.
Follow the manufacturer's recommendations for the care and maintenance of the dosing applicator.
Remove the draw-off cap and replace it with the original cap, tightening it firmly.
Contraindications
Use of this product is contraindicated in the following situations:
Female dairy cattle 20 months of age or older should not be treated with this product due to potential adverse effects. Additionally, it is contraindicated in calves intended for veal processing, as the safety and efficacy in this population have not been established.
This product is not to be used in other animal species, as severe adverse reactions, including fatalities in dogs, may occur.
Administration of this product should adhere to the following restrictions:
Underdosing is contraindicated; each animal must receive a complete dose based on current body weight to avoid ineffective treatment and the development of parasite resistance.
Oral or parenteral administration is prohibited.
Application to areas of skin that are caked with mud or manure is not recommended.
Handling the product while smoking or eating is contraindicated.
Cattle must not enter lakes, streams, or ponds for at least 6 hours post-treatment to prevent contamination.
Direct application to water sources or improper disposal of drug containers is strictly prohibited to avoid environmental contamination.
Warnings and Precautions
WARNING: Doracide Pour-On solution for cattle is flammable. It must be kept away from heat, sparks, open flames, and other sources of ignition. This product is not intended for human use and should be stored out of reach of children.
Irritation Precautions: The solution may cause irritation to human skin and eyes. Users are advised to avoid applying the product to themselves or to others. To minimize the risk of irritation, operators should wear appropriate protective clothing, which includes a long-sleeved shirt, protective gloves, and boots, along with a waterproof coat during application.
Post-Application Safety: After use, protective clothing should be thoroughly washed to remove any residual product. In the event of accidental skin contact, the affected area should be washed immediately with soap and water. If the solution comes into contact with the eyes, it is imperative to flush the eyes immediately with water and seek medical attention if irritation persists.
Side Effects
Patients using Doracide Pour-On solution for cattle should be aware of several adverse reactions and warnings associated with its use.
Serious adverse reactions may occur, particularly in cases of improper application or use in non-target species. Notably, the use of this product in other animal species has been associated with severe adverse reactions, including fatalities in dogs. Additionally, the destruction of Hypoderma larvae, particularly when located in critical areas, can lead to undesirable host-parasite reactions. For instance, killing H. lineatum while it is in the tissue surrounding the gullet may result in bloat, while the destruction of H. bovis in the vertebral canal may lead to staggering or paralysis. These reactions are not exclusive to Doracide Pour-On solution and can occur with any effective treatment of grubs.
Common adverse reactions include skin and eye irritation in humans. Users should exercise caution to avoid contact with skin and eyes. In the event of accidental skin contact, it is advised to wash the affected area immediately with soap and water. If the solution comes into contact with the eyes, it is crucial to flush the eyes with water immediately and seek medical attention.
Furthermore, it is important to note that the product is flammable; therefore, it should be kept away from heat, sparks, open flames, and other sources of ignition. It is not intended for human use and should be kept out of reach of children.
Drug Interactions
No specific drug interactions are noted for this product. However, it is essential to consider the following recommendations regarding laboratory test interactions and monitoring.
Prior to administering any dewormer, fecal examinations or other diagnostic tests, along with a thorough parasite management history, should be conducted to assess the appropriateness of the product for the herd. Following the administration of a dewormer, it is crucial to monitor the effectiveness of the treatment. This can be achieved through methods such as a fecal egg count reduction test or other suitable evaluation techniques.
It is important to note that a decrease in the effectiveness of the dewormer, as indicated by fecal egg count reduction tests, may suggest the development of resistance to the administered product. Regular monitoring and assessment are recommended to ensure continued efficacy and to guide future treatment decisions.
Packaging & NDC
The table below lists each NDC Code for Doracide (doramectin) veterinary formulations. Columns show Packaging, Formulation Type, and Active Ingredient Strength.
Details | ||||
|---|---|---|---|---|
| Solution | 5 mg/1 mL | ||
Product details Regulatory status — Marketed All current FDA data sets list this NDC as actively marketed. FDA record dates for this NDC:
Active ingredients
| ||||
Pediatric Use
Doracide Pour-On solution is indicated exclusively for use in cattle and is contraindicated in other animal species, including children, due to the potential for severe adverse reactions. Safety studies have shown that doramectin is safe for use in neonatal calves when treated with doses up to three times the recommended amount. However, it is important to note that this product is not approved for use in female dairy cattle that are 20 months of age or older. Additionally, a withdrawal period has not been established for this product in preruminating calves, and it should not be used in calves intended for veal processing.
Geriatric Use
Elderly patients may not have specific information regarding the use of this medication, including dosage adjustments, safety concerns, or special precautions. Therefore, healthcare providers should exercise caution when prescribing this medication to geriatric patients. It is advisable to monitor these patients closely for any adverse effects or changes in therapeutic response, given the lack of targeted data for this population.
Pregnancy
The use of Doracide Pour-On solution in pregnant cattle has been evaluated, demonstrating no adverse effects on breeding performance during critical developmental stages, including folliculogenesis, organogenesis, implantation, and throughout gestation. This assessment was conducted at a dose three times higher than the recommended dose of doramectin injectable solution. Additionally, a pharmacokinetic study revealed that systemic exposure to doramectin from the pour-on formulation is lower than that from the injectable solution. Currently, there are no specific warnings or contraindications associated with the use of Doracide Pour-On solution in pregnant cattle. Therefore, it is considered safe for use in this population, although standard precautions should always be observed when administering any medication to pregnant animals.
Lactation
There is no specific information available regarding the use of this medication in nursing mothers or lactation considerations. Healthcare professionals should exercise caution and consider the potential risks and benefits when prescribing this medication to lactating mothers. The effects on breastfed infants have not been established.
Renal Impairment
There is no information available regarding dosage adjustments, special monitoring, or safety considerations for patients with renal impairment. Healthcare professionals should exercise caution and consider the lack of data when prescribing to patients with reduced kidney function.
Hepatic Impairment
There is no information available regarding the use of this medication in patients with hepatic impairment. Consequently, there are no dosage adjustments, special monitoring requirements, or precautions specified for individuals with compromised liver function. Healthcare professionals should exercise caution and consider the lack of data when prescribing this medication to patients with liver problems.
Overdosage
In the absence of specific information regarding overdosage, healthcare professionals are advised to exercise caution and adhere to general principles of management in cases of suspected overdose.
It is essential to monitor the patient closely for any potential symptoms that may arise from an overdose. Symptoms can vary widely depending on the substance involved and the individual patient's response.
In the event of an overdose, immediate medical attention should be sought. Healthcare providers should implement supportive care measures, which may include monitoring vital signs, providing symptomatic treatment, and ensuring the patient's safety.
If available, consultation with a poison control center or a medical toxicologist is recommended to guide the management of the overdose effectively.
Documentation of the incident, including the substance involved, the amount taken, and the time of ingestion, is crucial for appropriate treatment and follow-up care.
Nonclinical Toxicology
In breeding studies involving bulls and cows during critical reproductive phases such as folliculogenesis, organogenesis, implantation, and throughout gestation, administration of doramectin injectable solution at a dose three times the recommended level did not adversely affect breeding performance.
Safety evaluations of doramectin have demonstrated a significant safety margin. Trials conducted in the United States revealed no toxic signs in cattle administered doses up to 25 times the recommended level of doramectin injectable solution. Additionally, a study involving neonatal calves treated with doramectin injectable solution at doses up to three times the recommended level also confirmed its safety.
A pharmacokinetic assessment indicated that systemic exposure to doramectin from the pour-on formulation was lower than that from the injectable solution.
Doramectin is derived from selected strains of the soil organism Streptomyces avermitilis. The primary mechanism of action for macrocyclic lactones, including doramectin, involves the modulation of chloride ion channel activity within the nervous systems of nematodes and arthropods. These compounds bind to specific receptors that enhance membrane permeability to chloride ions, leading to the inhibition of electrical activity in nerve cells of nematodes and muscle cells of arthropods, ultimately resulting in paralysis and death of the parasites. In mammals, the neuronal receptors targeted by macrocyclic lactones are primarily located within the central nervous system (CNS), where doramectin achieves only negligible concentrations.
Postmarketing Experience
Reports of adverse events associated with Doracide Pour-On solution for cattle have been received through voluntary reporting and surveillance programs. Users are advised that the product may cause skin and eye irritation; therefore, precautions should be taken to avoid contact with skin and eyes. Operators are recommended to wear protective clothing, including long-sleeved shirts, gloves, and waterproof boots, during application. In the event of accidental skin contact, the affected area should be washed immediately with soap and water, and if the product comes into contact with the eyes, they should be flushed with water, and medical attention sought.
Additionally, there is a potential for the development of parasite resistance to dewormers, including those in the same class as Doracide. It is important to implement appropriate parasite management practices tailored to the specific geographic area and the animals being treated to mitigate this risk. Prior to administering any dewormer, fecal examinations or other diagnostic tests should be conducted to assess the suitability of the product for the herd. Post-treatment monitoring of effectiveness, such as through fecal egg count reduction tests, is essential to detect any decrease in efficacy that may indicate resistance.
Furthermore, the destruction of Hypoderma larvae (cattle grubs) during critical developmental stages may lead to adverse host-parasite reactions, including fatalities. For instance, the treatment of H. lineatum in the tissue surrounding the gullet may result in bloat, while treatment of H. bovis in the vertebral canal may cause staggering or paralysis. These reactions are not exclusive to Doracide Pour-On solution and can occur with any effective treatment of grubs. It is recommended that cattle be treated either before or after the migratory phase of grub development, and consultation with a veterinarian is advised to determine the appropriate timing for treatment.
Patient Counseling
Healthcare providers should advise patients that Doracide Pour-On solution may cause irritation to human skin and eyes, and caution should be exercised to avoid applying the product to themselves or others. Operators are recommended to wear protective clothing, including a long-sleeved shirt, protective gloves, and boots with a waterproof coat during application. It is important to wash protective clothing after use to prevent any potential irritation.
In the event of accidental skin contact, patients should be instructed to wash the affected area immediately with soap and water. If the product comes into contact with the eyes, they should flush the eyes immediately with water and seek medical attention.
Patients should be informed that cattle must not be slaughtered for human consumption within 45 days of treatment with Doracide Pour-On solution. Additionally, this product is not intended for use in female dairy cattle that are 20 months of age or older. A withdrawal period has not been established for this product in preruminating calves, and it should not be used in calves intended for veal processing.
Healthcare providers should discuss the potential for parasite resistance to develop with any dewormer, as this has been reported for most classes of dewormers. It is advisable to implement treatment with a dewormer alongside appropriate parasite management practices tailored to the geographic area and the specific animals being treated, as this may help slow the development of resistance. Fecal examinations or other diagnostic tests, along with a review of the herd's parasite management history, should be conducted to determine the appropriateness of the product prior to use.
Following the administration of any dewormer, the effectiveness of the treatment should be monitored, for example, through fecal egg count reduction tests or other suitable methods. A decrease in the drug's effectiveness over time, as indicated by these tests, may suggest the development of resistance to the dewormer used. Patients should be encouraged to adjust their parasite management plan based on regular monitoring.
It is crucial to emphasize that Doracide Pour-On solution is specifically formulated for use in cattle only and should not be administered to other animal species, as severe adverse reactions, including fatalities in dogs, may occur. The product is intended for application to the skin surface only and should not be administered orally or parenterally. Patients should avoid applying the solution to areas of skin that are caked with mud or manure and should wash their hands thoroughly after use. Smoking or eating while handling the product is not recommended.
Patients should be informed that cloudiness in the formulation may occur if Doracide Pour-On solution is stored at temperatures below 0˚C (32˚F); however, allowing the product to warm to room temperature will restore its normal appearance without affecting its efficacy. It is advisable to consult a veterinarian regarding the appropriate timing for the treatment of cattle grubs. Cattle treated with Doracide Pour-On solution after the heel fly season may be re-treated during the winter for internal parasites, mange mites, or biting and sucking lice without the risk of grub-related reactions. A planned parasite control program is recommended, and varying weather conditions, including rainfall, do not affect the efficacy of Doracide Pour-On solution.
Storage and Handling
The product is supplied in containers that must be stored at temperatures below 25˚C (77˚F). It is essential to protect the product from light to maintain its integrity. Upon disposal, containers should be handled in accordance with local regulations, either by placing them in an approved landfill or by incineration.
Additional Clinical Information
No further data are available.
Drug Information (PDF)
This document includes the full labeling information for Doracide, as submitted by MWI/VetOne for veterinary use. It may include dosage by species, withdrawal periods, and administration instructions.