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Acid Reducer Complete

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Active ingredients
  • Famotidine 10 mg
  • Calcium Carbonate 800 mg
  • Magnesium Hydroxide 165 mg
Other brand names
Drug classes
Calculi Dissolution Agent, Histamine-2 Receptor Antagonist, Osmotic Laxative
Dosage form
Tablet, Chewable
Route
Oral
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2025
Label revision date
October 14, 2025
Drug Information (PDF)
Prescribing information, PDF file
Active ingredients
  • Famotidine 10 mg
  • Calcium Carbonate 800 mg
  • Magnesium Hydroxide 165 mg
Other brand names
Drug classes
Calculi Dissolution Agent, Histamine-2 Receptor Antagonist, Osmotic Laxative
Dosage form
Tablet, Chewable
Route
Oral
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2025
Label revision date
October 14, 2025
Manufacturer
Safeway
Registration number
ANDA077355
NDC root
21130-786
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info (2 NDCs)
Packaging & NDC Codes (2)

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

Signature SELECT is a chewable tablet designed to relieve heartburn associated with acid indigestion and sour stomach. It features a dual action formula that combines an acid reducer and an antacid, making it effective for quick relief. The active ingredients include famotidine (which reduces stomach acid), calcium carbonate, and magnesium hydroxide, all working together to help alleviate discomfort. With a cool mint flavor, just one tablet can help you feel better when experiencing heartburn.

Uses

You can use this medication to relieve heartburn that comes with acid indigestion and a sour stomach. It helps to ease the discomfort associated with these conditions, allowing you to feel more comfortable throughout your day.

Rest assured, there are no known teratogenic effects (which means it doesn't cause birth defects) or nonteratogenic effects associated with this medication. This makes it a safer option for those concerned about potential risks.

Dosage and Administration

When you need relief from your symptoms, and you are 12 years or older, take one chewable tablet. It's important that you chew the tablet completely before swallowing it—do not swallow it whole. You should not take more than two chewable tablets in a 24-hour period to avoid any potential issues.

If you are caring for a child under 12 years old, it's best to consult a doctor before giving them this medication. This ensures that they receive the appropriate care and dosage for their age.

What to Avoid

It's important to be cautious when considering this medication. You should not use it if you have difficulty swallowing food, are experiencing vomiting with blood, or have bloody or black stools, as these could indicate a serious health issue. In such cases, please consult your doctor immediately.

Additionally, avoid using this medication in combination with other acid reducers, as this can lead to unwanted effects. Always prioritize your health and safety by following these guidelines.

Side Effects

You should be aware of some important side effects and warnings associated with this medication. If you are allergic to famotidine or other acid reducers, do not use this product. Additionally, avoid using it if you have difficulty swallowing, are vomiting blood, or have bloody or black stools, as these could indicate a serious health issue that requires medical attention.

Before using this medication, consult your doctor if you have experienced heartburn for more than three months, or if you have heartburn accompanied by symptoms like lightheadedness, sweating, or chest pain. Other concerning signs include frequent wheezing, unexplained weight loss, nausea, vomiting, stomach pain, or if you have kidney disease. If your heartburn persists or worsens, or if you find yourself needing to use this product for more than 14 days, stop using it and seek medical advice.

Warnings and Precautions

You should not use this medication if you are allergic to famotidine or other acid reducers. Additionally, avoid using it if you have difficulty swallowing, are vomiting blood, or have bloody or black stools, as these could indicate a serious health issue. It's also important not to combine this medication with other acid reducers.

Before using this product, consult your doctor if you have experienced heartburn for more than three months, have heartburn accompanied by dizziness or lightheadedness, or if you have chest pain, frequent wheezing, unexplained weight loss, or any stomach pain. If your heartburn persists or worsens, or if you find you need to use this medication for more than 14 days, stop using it and contact your doctor.

In case of an overdose, seek emergency medical help immediately or contact a Poison Control Center at 1-800-222-1222.

Overdose

If you suspect an overdose, it’s crucial to seek medical help immediately. You can contact a Poison Control Center at 1-800-222-1222 for guidance. Signs of an overdose can vary, but they may include unusual drowsiness, confusion, or difficulty breathing.

Always err on the side of caution—if you notice any concerning symptoms or if you’re unsure, don’t hesitate to get help right away. Your health and safety are the top priority.

Pregnancy Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using this medication. They can provide guidance on whether it’s safe for you and your baby. Always prioritize your health and the health of your child by seeking expert advice.

Lactation Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using any medication. This ensures that you understand any potential risks and can make informed decisions about your health and the health of your baby. Always prioritize open communication with your doctor regarding your breastfeeding journey and any medications you may consider.

Pediatric Use

If you have a child under 12 years old, it's important to consult with a doctor before using this medication. For children aged 12 and older, the medication should be taken differently than you might expect. Make sure they chew the tablet completely before swallowing it to help relieve their symptoms effectively.

Additionally, remind them not to take more than 2 chewable tablets within a 24-hour period to ensure their safety. Always follow these guidelines to help keep your child safe and healthy.

Geriatric Use

While there is no specific information about how this medication should be used by older adults, it’s important to approach any new treatment with caution. If you or a loved one is an older adult, it’s always a good idea to discuss any medications with a healthcare provider. They can help ensure that the treatment is safe and appropriate, considering any unique health needs or conditions that may be present.

Since there are no dosage adjustments or special precautions mentioned for elderly patients, your healthcare provider will be the best resource for personalized advice. Always keep them informed about any other medications or health issues to help manage your care effectively.

Renal Impairment

If you have kidney disease, it's important to consult your doctor before using this medication. Your healthcare provider can help determine if it's safe for you and if any adjustments to your dosage are necessary. Always prioritize open communication with your doctor regarding your kidney health to ensure the best care.

Hepatic Impairment

If you have liver problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or precautions for your condition. This means that there are no tailored guidelines for how this medication should be used if you have hepatic impairment (liver issues).

Always consult your healthcare provider for personalized advice and to ensure that any medication you take is safe and appropriate for your liver health. They can help determine the best course of action based on your individual situation.

Drug Interactions

It's important to be aware that some over-the-counter medications, like antacids and acid reducers, can interact with certain prescription drugs you may be taking. These interactions can affect how well your medications work or increase the risk of side effects.

Since there are no specific drug interactions or laboratory test interactions listed, it's still crucial to discuss all medications, including over-the-counter products, with your healthcare provider. This ensures that you receive the safest and most effective treatment tailored to your needs. Always keep your healthcare team informed about everything you are taking.

Storage and Handling

To ensure the best performance of your product, store it in a cool, dry place at a temperature between 20-25°C (68-77°F). It's important to keep it protected from moisture, as this can affect its effectiveness and safety.

When handling the product, always do so with clean hands and in a clean environment to maintain its integrity. Following these guidelines will help you use the product safely and effectively.

Additional Information

You should take this medication orally. If you are an adult or a child aged 12 years and older, remember to chew the tablet completely before swallowing it. For symptom relief, chew one tablet, but do not exceed two chewable tablets in a 24-hour period. If the patient is under 12 years old, consult a doctor for guidance.

If you are pregnant or breastfeeding, it's important to speak with a healthcare professional before using this medication. Always keep it out of reach of children. In case of an overdose, seek medical help immediately or contact a Poison Control Center at 1-800-222-1222.

FAQ

What is Signature SELECT used for?

Signature SELECT relieves heartburn associated with acid indigestion and sour stomach.

What are the active ingredients in Signature SELECT?

The active ingredients include famotidine (10 mg), calcium carbonate (800 mg), and magnesium hydroxide (165 mg).

How should I take Signature SELECT?

Chew 1 tablet completely before swallowing. Do not swallow the tablet whole, and do not use more than 2 chewable tablets in 24 hours.

Can children use Signature SELECT?

Children under 12 years should ask a doctor before use.

What should I do if I experience severe symptoms?

Do not use Signature SELECT if you have trouble swallowing, vomiting with blood, or bloody or black stools. These may indicate a serious condition, and you should see a doctor.

Are there any warnings associated with Signature SELECT?

Yes, do not use if you are allergic to famotidine or other acid reducers. Consult a doctor if you have had heartburn for over 3 months or experience other serious symptoms.

What should I do if my heartburn worsens?

Stop using Signature SELECT and consult a doctor if your heartburn continues or worsens, or if you need to take it for more than 14 days.

Is it safe to use Signature SELECT during pregnancy or breastfeeding?

If you are pregnant or breastfeeding, ask a health professional before use.

How should I store Signature SELECT?

Store Signature SELECT at 20-25°C (68-77°F) and protect it from moisture.

Packaging Info

Below are the non-prescription pack sizes of Acid Reducer Complete (famotidine, calcium carbonate, magnesium hydroxide). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Acid Reducer Complete.
Details

Drug Information (PDF)

This file contains official product information for Acid Reducer Complete, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the drug.

Uses and Indications

This drug is indicated for the relief of heartburn associated with acid indigestion and sour stomach.

There are no teratogenic effects associated with this drug, nor are there any nonteratogenic effects mentioned.

Dosage and Administration

Adults and children aged 12 years and older are instructed to chew 1 tablet completely before swallowing to relieve symptoms. It is essential that the tablet is not swallowed whole. The maximum recommended dosage is 2 chewable tablets within a 24-hour period.

For children under 12 years of age, it is advised to consult a physician before use.

Contraindications

Use is contraindicated in patients who experience difficulty or pain when swallowing food, vomiting with blood, or the presence of bloody or black stools, as these may indicate a serious underlying condition requiring medical evaluation. Additionally, concurrent use with other acid-reducing agents is contraindicated due to the potential for increased risk of adverse effects.

Warnings and Precautions

Patients should be advised of the following warnings and precautions associated with the use of this medication.

Allergy Alert This medication should not be used by individuals who are allergic to famotidine or other acid reducers.

Contraindications The medication is contraindicated in patients experiencing difficulty or pain when swallowing food, vomiting with blood, or the presence of bloody or black stools, as these symptoms may indicate a serious underlying condition. Such patients should seek medical attention promptly. Additionally, this medication should not be used concurrently with other acid reducers.

Pre-Use Consultation Healthcare professionals should recommend that patients consult a physician prior to use if they have experienced heartburn for more than three months, as this may suggest a more serious condition. Patients should also seek medical advice if they experience heartburn accompanied by lightheadedness, sweating, or dizziness; chest or shoulder pain with shortness of breath, sweating, or pain radiating to the arms, neck, or shoulders; frequent chest pain; or frequent wheezing, particularly in conjunction with heartburn. Other concerning symptoms that warrant consultation include unexplained weight loss, nausea or vomiting, stomach pain, or a history of kidney disease.

Discontinuation of Use Patients should discontinue use and consult a healthcare provider if heartburn persists or worsens, or if the medication is required for more than 14 days.

Emergency Assistance In the event of an overdose, patients should seek emergency medical assistance or contact a Poison Control Center immediately at 1-800-222-1222.

Side Effects

Patients should be aware of the potential adverse reactions associated with the use of this medication. Serious adverse reactions may occur, and patients are advised to discontinue use and consult a healthcare professional if they experience any of the following symptoms: difficulty or pain when swallowing food, vomiting with blood, or the presence of bloody or black stools, as these may indicate a serious underlying condition.

Patients should also seek medical advice prior to using this medication if they have experienced heartburn for more than three months, as this may signal a more serious condition. Additional symptoms that warrant consultation include heartburn accompanied by lightheadedness, sweating, or dizziness; chest pain or shoulder pain with shortness of breath, sweating, or pain radiating to the arms, neck, or shoulders; frequent chest pain; frequent wheezing, particularly in conjunction with heartburn; unexplained weight loss; nausea or vomiting; stomach pain; or a history of kidney disease.

Common adverse reactions may include persistent heartburn or worsening symptoms. Patients are advised to stop using the medication and consult a healthcare provider if their heartburn continues or worsens, or if they find it necessary to use the product for more than 14 days.

It is important to note that individuals with known allergies to famotidine or other acid reducers should not use this medication. Additionally, the use of this product in conjunction with other acid reducers is not recommended.

Drug Interactions

Antacids and acid reducers have the potential to interact with certain prescription medications. The mechanism of these interactions typically involves alterations in gastric pH, which can affect the solubility and absorption of various drugs.

Healthcare professionals should be aware of these interactions and consider monitoring patients for any changes in therapeutic efficacy or adverse effects when prescribing medications alongside antacids or acid reducers. Adjustments to dosages may be necessary based on the specific drugs involved and the clinical context.

No additional drug interactions or laboratory test interactions have been reported.

Packaging & NDC

Below are the non-prescription pack sizes of Acid Reducer Complete (famotidine, calcium carbonate, magnesium hydroxide). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Acid Reducer Complete.
Details

Pediatric Use

Pediatric patients under 12 years of age should consult a healthcare professional before use. For adolescents and adults aged 12 years and older, it is important to note that the tablet must not be swallowed whole; it should be chewed completely before swallowing. To alleviate symptoms, patients should chew 1 tablet prior to swallowing, with a maximum dosage of 2 chewable tablets within a 24-hour period.

Geriatric Use

There is no specific information regarding the use of this medication in geriatric patients, including dosage adjustments, safety concerns, or special precautions. Healthcare providers should exercise caution when prescribing this medication to elderly patients, as individual responses may vary. It is advisable to monitor these patients closely for any adverse effects or changes in efficacy.

Pregnancy

Pregnant patients and those who are breastfeeding should consult a healthcare professional prior to using this medication. The potential risks and benefits must be carefully considered in these populations to ensure maternal and fetal safety.

Lactation

Lactating mothers are advised to consult a health professional prior to using this medication. There is currently no available data regarding the excretion of this medication in human breast milk or its effects on breastfed infants. Therefore, caution is recommended when administering this medication to lactating individuals.

Renal Impairment

Patients with renal impairment should consult a healthcare professional prior to use, particularly if they have a history of kidney disease. It is essential to assess renal function and consider potential dosing adjustments or monitoring requirements based on the degree of impairment.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to this drug. Consequently, there are no dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the prescribing information.

Overdosage

In the event of an overdose, it is imperative to seek immediate medical assistance or contact a Poison Control Center without delay. Healthcare professionals should advise patients or caregivers to call the Poison Control Center at 1-800-222-1222 for guidance.

Prompt intervention is crucial in managing overdose situations, as timely medical support can significantly influence outcomes. Symptoms of overdose may vary depending on the substance involved, and healthcare providers should be prepared to assess and manage these symptoms accordingly.

Management procedures may include supportive care, monitoring of vital signs, and symptomatic treatment as necessary. It is essential for healthcare professionals to remain vigilant and act swiftly to mitigate potential complications associated with overdose.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data in these areas limits the understanding of the compound's potential effects in nonclinical settings.

Postmarketing Experience

No postmarketing experience details are available in the insert.

Patient Counseling

Patients should be advised to seek immediate medical assistance or contact a Poison Control Center at 1-800-222-1222 in the event of an overdose. It is important to inform patients that they should not use this medication if they experience difficulty or pain while swallowing food, vomiting blood, or passing bloody or black stools, as these symptoms may indicate a serious underlying condition that requires medical evaluation.

Patients should be cautioned against using this product in conjunction with other acid reducers, as this may lead to adverse effects. They should be instructed to discontinue use and consult a healthcare provider if their heartburn persists or worsens. Additionally, patients should be advised not to use this product for more than 14 days without consulting a doctor.

Healthcare providers should encourage patients to seek medical advice before using this medication if they have experienced heartburn for over three months, as this may signal a more serious condition. Patients should also be informed to consult a doctor if they experience heartburn accompanied by lightheadedness, sweating, or dizziness, or if they have chest pain or shoulder pain along with shortness of breath, sweating, or pain radiating to the arms, neck, or shoulders.

Patients should be advised to seek medical consultation if they experience frequent chest pain, wheezing (especially in conjunction with heartburn), unexplained weight loss, nausea, vomiting, or stomach pain. Furthermore, individuals with a history of kidney disease should consult a healthcare provider before using this product.

Lastly, patients should be encouraged to speak with their doctor or pharmacist prior to use if they are currently taking any prescription medications, as antacids and acid reducers may interact with certain drugs.

Storage and Handling

The product is supplied in packaging that ensures its integrity during storage and handling. It should be stored at a temperature range of 20-25°C (68-77°F) to maintain its efficacy. Additionally, it is essential to protect the product from moisture to prevent degradation. Proper adherence to these storage conditions is crucial for preserving the quality of the product.

Additional Clinical Information

The medication is administered orally, with specific instructions for different age groups. For adults and children aged 12 years and older, the tablet should not be swallowed whole; it must be chewed completely. To alleviate symptoms, patients should chew one tablet before swallowing, with a maximum of two chewable tablets allowed within a 24-hour period. For children under 12 years, consultation with a doctor is advised prior to use.

Clinicians should counsel patients on important safety information. Pregnant or breastfeeding individuals should seek advice from a health professional before using the medication. It is essential to keep the product out of reach of children, and in the event of an overdose, immediate medical assistance should be sought or contact with a Poison Control Center (1-800-222-1222) is recommended.

Drug Information (PDF)

This file contains official product information for Acid Reducer Complete, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Acid Reducer Complete, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

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Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.