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G-Supress Dx

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Active ingredients
  • Guaifenesin 50 mg/1 mL
  • Dextromethorphan Hydrobromide 5 mg/1 mL
  • Phenylephrine Hydrochloride 2.5 mg/1 mL
Other brand names
Drug classes
Expectorant, Sigma-1 Agonist, Uncompetitive N-methyl-D-aspartate Receptor Antagonist, alpha-1 Adrenergic Agonist
Dosage form
Syrup
Route
Oral
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2011
Label revision date
November 12, 2025
Drug Information (PDF)
Prescribing information, PDF file
Active ingredients
  • Guaifenesin 50 mg/1 mL
  • Dextromethorphan Hydrobromide 5 mg/1 mL
  • Phenylephrine Hydrochloride 2.5 mg/1 mL
Other brand names
Drug classes
Expectorant, Sigma-1 Agonist, Uncompetitive N-methyl-D-aspartate Receptor Antagonist, alpha-1 Adrenergic Agonist
Dosage form
Syrup
Route
Oral
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2011
Label revision date
November 12, 2025
Manufacturer
KRAMER NOVIS
Registration number
M012
NDC root
52083-655
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info
Packaging & NDC Codes

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

G-Supress DX is a medication designed to help you breathe easier by loosening phlegm (mucus) and thinning bronchial secretions. This action helps drain your bronchial tubes, making your coughs more productive.

In addition to its expectorant properties, G-Supress DX temporarily relieves nasal congestion caused by hay fever or other upper respiratory allergies, as well as coughs resulting from minor throat and bronchial irritation, which can occur with the common cold.

Uses

This medication is designed to help you breathe easier by loosening phlegm (mucus) and thinning bronchial secretions. This action helps drain your bronchial tubes, making your coughs more productive, which can be especially helpful when you're dealing with respiratory issues.

Additionally, it provides temporary relief from nasal congestion caused by hay fever or other upper respiratory allergies (known as allergic rhinitis). If you're experiencing a cough due to minor throat and bronchial irritation, such as what might happen with a common cold, this medication can also help alleviate that discomfort.

Dosage and Administration

When using this medication, it's important to follow the dosing instructions carefully to ensure safety and effectiveness. You should not take more than 6 doses within a 24-hour period, and doses should be spaced out by at least 4 hours. To measure your dose accurately, always use the dosage device that comes with the medication; do not use any other measuring tools.

For children aged 2 to under 6 years, the recommended dose is 1 mL. However, if your child is under 2 years old, you should not use this medication at all. Always consult with a healthcare professional if you have any questions or concerns about the appropriate use of this medication.

What to Avoid

It's important to keep this medication out of the reach of children to ensure their safety. If you suspect an overdose, seek medical help immediately or contact a Poison Control Center for assistance.

There are no specific contraindications, controlled substance classifications, or noted risks of abuse, misuse, or dependence associated with this medication. However, always use it responsibly and as directed.

Side Effects

It's important to be aware of potential side effects when using this medication. You should not use it if your child is currently taking a monoamine oxidase inhibitor (MAOI), which is a type of medication for depression or certain other conditions, or for two weeks after stopping an MAOI. Before using this medication, consult a doctor if your child has heart disease, thyroid disease, high blood pressure, diabetes, or a cough that produces a lot of mucus or lasts a long time, such as with asthma.

If your child experiences nervousness, dizziness, or sleeplessness, or if symptoms do not improve within seven days or are accompanied by a fever, you should stop use and consult a doctor. Additionally, if a cough lasts more than seven days, returns, or is accompanied by fever, rash, or a persistent headache, these could indicate a more serious issue. In case of an overdose, seek medical help or contact a Poison Control Center immediately.

Warnings and Precautions

It's important to be cautious when giving this medication to your child. Do not use it if your child is currently taking a monoamine oxidase inhibitor (MAOI), which is a type of medication for depression or certain other conditions, or if they have stopped taking it within the last two weeks. If you're unsure whether your child's prescription includes an MAOI, please consult a doctor or pharmacist.

Before using this product, check with a doctor if your child has any of the following conditions: heart disease, thyroid disease, high blood pressure, diabetes, or a cough that produces a lot of mucus or lasts a long time, such as with asthma. Always follow the dosing instructions carefully and do not exceed the recommended amount.

If your child experiences nervousness, dizziness, or trouble sleeping, or if their symptoms do not improve within 7 days or are accompanied by a fever, stop using the medication and contact a doctor. Additionally, if the cough lasts more than 7 days, returns, or is accompanied by fever, rash, or a persistent headache, seek medical advice. In case of an overdose, get medical help or contact a Poison Control Center immediately.

Overdose

If you suspect an overdose, it’s crucial to seek medical help immediately or contact a Poison Control Center. Signs of an overdose can vary, but they may include unusual symptoms that are more severe than typical side effects.

Always err on the side of caution—if you notice anything concerning, don’t hesitate to reach out for professional assistance. Your health and safety are the top priority.

Pregnancy Use

If you are pregnant or planning to become pregnant, it's important to know that the safety of this product during pregnancy has not been established. Due to potential risks to the developing fetus, it is not recommended for use while you are pregnant.

Before using this product, please consult your healthcare provider to discuss any concerns and to ensure the best care for you and your baby. Your health and safety, as well as that of your child, should always come first.

Lactation Use

If you are breastfeeding or planning to breastfeed, it's important to talk to your healthcare professional before using this medication. There is a possibility that the medication can pass into your breast milk, so caution is advised.

The effects of this medication on your nursing infant have not been thoroughly studied, which means you should carefully weigh the potential risks against the benefits before making a decision. Your healthcare provider can help you understand these factors and guide you in making the best choice for you and your baby.

Pediatric Use

It's important to be cautious when giving medication to children. If your child is taking a prescription monoamine oxidase inhibitor (MAOI) or has stopped taking one in the last two weeks, do not use this medication. Before giving it to your child, consult a doctor if they have any of the following conditions: heart disease, thyroid disease, high blood pressure, diabetes, or a cough that produces a lot of mucus or lasts a long time, such as with asthma.

For children aged 2 to under 6 years, the recommended dose is 1 mL, but do not use this medication for children under 2 years old. Make sure not to exceed 6 doses in a 24-hour period. If your child experiences nervousness, dizziness, or sleeplessness, or if their symptoms do not improve within 7 days, or if they develop a fever, rash, or persistent headache, stop using the medication and consult a doctor.

Geriatric Use

When it comes to using this medication in older adults, there is no specific information available about dosage adjustments, safety concerns, or special precautions. This means that if you or a loved one is an older adult, it’s important to consult with a healthcare provider before starting the medication. They can help determine the best approach based on individual health needs and any other medications being taken. Always prioritize open communication with your healthcare team to ensure safe and effective treatment.

Renal Impairment

If you have kidney problems, it's important to know that there are no specific guidelines or dosage adjustments mentioned for your condition in the available information. This means that the usual recommendations for monitoring or safety considerations related to renal impairment (kidney issues) are not provided.

Always consult your healthcare provider for personalized advice and to ensure that any medications you take are safe and appropriate for your kidney health. They can help you understand how your condition may affect your treatment and what steps to take for your safety.

Hepatic Impairment

If you have liver problems, it's important to know that there are no specific guidelines or dosage adjustments mentioned for your condition in the available information. This means that the standard recommendations apply, but you should always consult your healthcare provider for personalized advice. They can help determine the best approach for your treatment and monitor your liver function as needed.

Make sure to keep your doctor informed about your liver health, as they may want to conduct regular tests to ensure your safety while using any medication. Your well-being is a priority, so don't hesitate to ask questions or express any concerns you may have.

Drug Interactions

It's important to be cautious when using certain medications, especially if you or your child are taking a prescription monoamine oxidase inhibitor (MAOI). You should avoid using dextromethorphan, a common cough suppressant, in children who are on an MAOI or for two weeks after stopping one. This is because combining these medications can lead to serious interactions that may affect health.

Always discuss any medications you are taking, including over-the-counter drugs, with your healthcare provider. They can help ensure that your treatments are safe and effective, and they can provide guidance tailored to your specific health needs.

Storage and Handling

To ensure the safety and effectiveness of your product, always check that the printed seal is intact before use; do not use it if the seal is torn, broken, or missing. For proper storage, keep the product at a controlled room temperature between 15-30°C (59-86°F) and protect it from excessive heat and humidity, as these conditions can affect its quality.

When handling the product, make sure to do so in a clean environment to maintain its integrity. Following these guidelines will help you use the product safely and effectively.

Additional Information

No further information is available.

FAQ

What is G-Supress DX used for?

G-Supress DX helps loosen phlegm (mucus) and thin bronchial secretions, making coughs more productive. It also temporarily relieves nasal congestion due to hay fever or other upper respiratory allergies.

How should I use G-Supress DX?

You should measure the dosage with the provided device and not use any other device. For children aged 2 to under 6 years, the dosage is 1 mL, and you should not exceed 6 doses in a 24-hour period.

Are there any warnings for using G-Supress DX?

Do not use G-Supress DX in children taking a prescription monoamine oxidase inhibitor (MAOI) or for 2 weeks after stopping an MAOI. Consult a doctor if the child has heart disease, thyroid disease, high blood pressure, diabetes, or a chronic cough.

What should I do if my child experiences side effects?

Stop using G-Supress DX and consult a doctor if your child becomes nervous, dizzy, or sleepless, or if symptoms do not improve within 7 days or are accompanied by fever.

Is G-Supress DX safe during pregnancy?

The safety of G-Supress DX during pregnancy has not been established, and it is not recommended for use due to potential risks to the fetus.

Can nursing mothers use G-Supress DX?

Nursing mothers should consult a healthcare professional before using G-Supress DX, as there is a potential for the medication to be excreted in breast milk.

What should I do in case of an overdose?

In case of overdose, seek medical help or contact a Poison Control Center immediately.

How should G-Supress DX be stored?

Store G-Supress DX at a controlled room temperature of 15-30°C (59-86°F) and avoid excessive heat and humidity.

Packaging Info

Below are the non-prescription pack sizes of G-Supress Dx (dextromethorphan hydrobromide, guaifenesin, phenylephrine hydrochloride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for G-Supress Dx.
Details

Drug Information (PDF)

This file contains official product information for G-Supress Dx, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the specified drug.

Uses and Indications

This drug is indicated for the relief of symptoms associated with upper respiratory conditions. It helps to loosen phlegm (mucus) and thin bronchial secretions, facilitating drainage of the bronchial tubes and enhancing the productivity of coughs.

This drug temporarily relieves nasal congestion due to hay fever or other upper respiratory allergies (allergic rhinitis). Additionally, it alleviates cough resulting from minor throat and bronchial irritation, which may occur with the common cold.

There are no teratogenic or nonteratogenic effects mentioned in the available data.

Dosage and Administration

The maximum recommended dosage is 6 doses within a 24-hour period. Dosing should be repeated every 4 hours as needed. It is essential to measure the dosage using the device provided with the medication; the use of any other measuring device is not advised.

For children aged 2 to under 6 years, the appropriate dosage is 1 mL. The medication is not indicated for use in children under 2 years of age.

Contraindications

There are no specific contraindications associated with this product. However, it is essential to keep the product out of the reach of children to prevent accidental ingestion. In the event of an overdose, immediate medical assistance should be sought, or contact a Poison Control Center for guidance.

Warnings and Precautions

The use of this product is contraindicated in children who are currently taking a prescription monoamine oxidase inhibitor (MAOI) or have taken an MAOI within the past two weeks. MAOIs are commonly prescribed for depression, psychiatric or emotional conditions, and Parkinson's disease. If there is uncertainty regarding whether a child's prescription includes an MAOI, it is imperative to consult a healthcare professional, such as a doctor or pharmacist, prior to administration.

Healthcare professionals should advise caregivers to seek medical guidance before using this product if the child has any of the following conditions: heart disease, thyroid disease, high blood pressure, diabetes, a cough associated with excessive phlegm (mucus), or a chronic cough, such as that which occurs with asthma.

It is essential to adhere strictly to the recommended dosage when using this product. Caregivers should be instructed to discontinue use and consult a physician if the child experiences nervousness, dizziness, or insomnia. Additionally, if symptoms do not improve within seven days or are accompanied by fever, or if a cough persists beyond seven days, recurs, or is associated with fever, rash, or a persistent headache, medical advice should be sought. These symptoms may indicate a more serious underlying condition.

In the event of an overdose, immediate medical assistance should be obtained, or the Poison Control Center should be contacted without delay.

Side Effects

Patients should be aware of the potential adverse reactions associated with the use of this medication. Serious adverse reactions may occur, particularly in children who are concurrently taking a prescription monoamine oxidase inhibitor (MAOI) or have taken one within the past two weeks. It is crucial to consult a healthcare professional before use if the child has a history of heart disease, thyroid disease, high blood pressure, diabetes, or chronic cough, especially if the cough is associated with excessive phlegm or conditions such as asthma.

Common adverse reactions may include nervousness, dizziness, or sleeplessness. If any of these symptoms occur, it is advised to discontinue use and seek medical advice. Additionally, if symptoms do not improve within seven days or are accompanied by fever, or if a cough persists for more than seven days, recurs, or is associated with fever, rash, or a persistent headache, these may indicate a serious underlying condition that requires medical evaluation.

In the event of an overdose, immediate medical assistance should be sought, or the Poison Control Center should be contacted without delay.

Drug Interactions

Dextromethorphan should not be administered to children who are concurrently taking a prescription monoamine oxidase inhibitor (MAOI) or within two weeks of discontinuing an MAOI. This contraindication is due to the potential for serious interactions that may arise from the combination of these substances.

No additional drug interactions or laboratory test interactions have been identified for dextromethorphan. Therefore, no further dosage adjustments or monitoring recommendations are necessary beyond the aforementioned contraindication.

Packaging & NDC

Below are the non-prescription pack sizes of G-Supress Dx (dextromethorphan hydrobromide, guaifenesin, phenylephrine hydrochloride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for G-Supress Dx.
Details

Pediatric Use

Pediatric patients should not use this medication if they are currently taking a prescription monoamine oxidase inhibitor (MAOI) or within 2 weeks of stopping an MAOI. Prior to administration, it is essential to consult a healthcare professional if the child has any of the following conditions: heart disease, thyroid disease, high blood pressure, diabetes, or a cough associated with excessive phlegm or chronic conditions such as asthma.

For children aged 2 to under 6 years, the recommended dosage is 1 mL. The medication is contraindicated in children under 2 years of age. It is important to limit the use to no more than 6 doses within a 24-hour period.

Parents or caregivers should discontinue use and seek medical advice if the child experiences nervousness, dizziness, or sleeplessness, if symptoms do not improve within 7 days or are accompanied by fever, or if the cough persists for more than 7 days, recurs, or is associated with fever, rash, or a persistent headache.

Geriatric Use

There is no specific information available regarding the use of this medication in geriatric patients, including dosage adjustments, safety concerns, or special precautions. Healthcare providers should exercise caution when prescribing this medication to elderly patients, as individual responses may vary. It is advisable to monitor these patients closely for any adverse effects or changes in efficacy, given the lack of targeted data for this population.

Pregnancy

Safety during pregnancy has not been established for this product. It is contraindicated for use during pregnancy due to potential risks to the fetus. Pregnant patients or those planning to become pregnant should consult a healthcare provider before using this product to discuss potential risks and benefits.

Lactation

Nursing mothers should consult a healthcare professional before using this product. There is a potential for excretion in breast milk; therefore, caution is advised when administering this medication to lactating mothers. The effects of this medication on a nursing infant are not well studied; thus, the risks versus benefits should be carefully considered.

Renal Impairment

There is no specific information available regarding dosage adjustments, special monitoring, or safety considerations for patients with renal impairment. Healthcare professionals should exercise caution when prescribing to patients with reduced kidney function, as the absence of detailed guidance necessitates careful clinical judgment. Regular monitoring of renal function may be advisable in these patients to ensure safety and efficacy.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

In the event of an overdose, it is imperative to seek immediate medical assistance or contact a Poison Control Center without delay. Prompt intervention is crucial to mitigate potential adverse effects associated with the overdose.

Healthcare professionals should be vigilant in monitoring for symptoms that may arise from an overdose. While specific symptoms are not detailed in the provided information, it is essential to assess the patient for any signs of toxicity or distress.

Management of an overdose should be guided by established protocols, which may include supportive care and symptomatic treatment as necessary. Continuous evaluation of the patient's condition is recommended to ensure appropriate interventions are implemented in a timely manner.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the use of the compound in these contexts.

Postmarketing Experience

Serious side effects have been reported voluntarily through various channels, including surveillance programs. Healthcare professionals and patients are encouraged to report any serious adverse events to the designated phone number available on weekdays from 8 AM to 4 PM AST. This reporting contributes to the ongoing monitoring of the product's safety profile.

Patient Counseling

Healthcare providers should advise patients to keep this medication out of the reach of children to prevent accidental ingestion. It is crucial to emphasize the importance of safety in the home environment, particularly for households with young children.

In the event of an overdose, healthcare providers should instruct patients to seek medical help immediately or contact a Poison Control Center. Patients should be made aware of the signs of overdose and the urgency of obtaining assistance to ensure their safety and well-being.

Storage and Handling

The product is supplied in packaging that ensures integrity and safety. It is essential to inspect the printed seal before use; the product should not be utilized if the seal is torn, broken, or missing.

For optimal storage, the product must be kept at a controlled room temperature ranging from 15 to 30°C (59 to 86°F). It is crucial to avoid exposure to excessive heat and humidity to maintain the product's efficacy and safety. Proper handling and storage conditions are vital to ensure the product remains in good condition until its expiration.

Additional Clinical Information

No further data are available.

Drug Information (PDF)

This file contains official product information for G-Supress Dx, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for G-Supress Dx, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

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Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.