Glycerin

Description

No description information is available for the drug.

Uses and Indications

This drug is indicated for the relief of occasional constipation. It generally produces a bowel movement within 15 minutes to 1 hour after administration.

There are no known teratogenic or nonteratogenic effects associated with this product.

Dosage and Administration

For children aged 2 to under 6 years, the recommended dosage is one suppository administered once daily, or as directed by a healthcare professional. For children under 2 years of age, it is advised to consult a physician prior to administration.

The suppository should be inserted well up into the rectum to ensure proper placement. It is important to note that the suppository does not need to melt completely in order to achieve the desired laxative effect.

Contraindications

Use of this product is contraindicated in children who exhibit rectal bleeding or have not experienced a bowel movement after using the product.

Consult a healthcare professional prior to use in children presenting with abdominal pain, nausea, or vomiting, those with a sudden change in bowel habits lasting more than two weeks, or if a laxative has been used for more than one week.

Warnings and Precautions

For rectal use only, this product may cause rectal discomfort or a burning sensation. Healthcare professionals should advise patients to monitor for these potential side effects.

Before recommending this laxative, it is essential to consult a physician if the child presents with any of the following conditions: abdominal pain, nausea, or vomiting; a sudden change in bowel habits lasting more than two weeks; or if a laxative has already been used for more than one week. These precautions are critical to ensure the safe use of the product.

Patients should be instructed to discontinue use and seek medical advice if the child experiences rectal bleeding or does not have a bowel movement after using this product. These symptoms may indicate a serious underlying condition that requires further evaluation.

In the event of accidental ingestion, immediate medical assistance should be sought, or the Poison Control Center should be contacted without delay. Prompt action is necessary to address potential toxicity.

Side Effects

Patients using this product may experience adverse reactions, which can include rectal discomfort or a burning sensation, particularly with rectal use. It is important to note that this product is intended for rectal administration only.

In clinical practice, it is advised that patients consult a healthcare professional before using any laxative if they have a history of abdominal pain, nausea, or vomiting, or if they have experienced a sudden change in bowel habits lasting more than two weeks. Additionally, if a laxative has been used for more than one week, medical advice should be sought prior to continued use.

Patients should discontinue use and seek medical attention if they experience rectal bleeding or if there is no bowel movement following the use of this product, as these symptoms may indicate a serious underlying condition.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there is no information available regarding interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Glycerin. Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Pediatric Use

Pediatric patients should be evaluated by a healthcare professional before using any laxative if they present with abdominal pain, nausea, vomiting, a sudden change in bowel habits lasting more than two weeks, or if they have already used a laxative for more than one week.

If a child experiences rectal bleeding or does not have a bowel movement after using this product, use should be discontinued, and a doctor should be consulted immediately.

For dosing, the recommended single daily dosage for children aged 2 to under 6 years is 1 suppository, or as directed by a healthcare professional. For children under 2 years, it is advised to consult a doctor before use.

It is essential to keep this product out of reach of children. In the event of accidental ingestion, medical assistance should be sought or a Poison Control Center contacted without delay.

Geriatric Use

Elderly patients may not have specific information regarding the use of this medication, including dosage adjustments, safety concerns, or special precautions. Therefore, healthcare providers should exercise caution when prescribing this medication to geriatric patients. It is advisable to monitor these patients closely for any potential adverse effects or changes in efficacy, given the lack of targeted data for this population.

Pregnancy

There is no specific information available regarding the use of Glycerin suppositories during pregnancy. As such, the safety of this medication in pregnant patients has not been established. There are no known dosage modifications or special precautions indicated for use during pregnancy. Healthcare professionals should weigh the potential benefits against any unknown risks when considering the use of Glycerin suppositories in pregnant patients. Women of childbearing potential should be counseled accordingly.

Lactation

Nursing mothers should consult a doctor before using this product. There is a potential for excretion in breast milk, and the effects on nursing infants are not well studied; therefore, caution is advised.

Renal Impairment

Patients with renal impairment have no specific information regarding dosage adjustments, special monitoring, or safety considerations provided in the insert text. Therefore, healthcare professionals should exercise caution when prescribing this medication to patients with reduced kidney function, as the lack of data necessitates careful clinical judgment. Regular monitoring of renal function may be advisable in these patients to ensure safety and efficacy.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

In the event of an overdosage, immediate medical assistance is crucial. If the substance is ingested, healthcare professionals should advise patients or caregivers to seek medical help or contact a Poison Control Center without delay.

Prompt intervention is essential to mitigate potential adverse effects associated with overdosage. Symptoms may vary depending on the specific substance involved; therefore, a thorough assessment by a medical professional is recommended to determine the appropriate course of action.

Management procedures may include supportive care and symptomatic treatment, tailored to the individual patient's needs. It is imperative that healthcare providers remain vigilant and prepared to address any complications that may arise from an overdosage scenario.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the use of the compound in question. Further studies may be necessary to elucidate these aspects of nonclinical toxicology.

Postmarketing Experience

Postmarketing experience has not been detailed in the provided text.

Patient Counseling

Healthcare providers should advise patients to keep this product out of reach of children to prevent accidental ingestion. Instruct patients that if the product is swallowed, they should seek medical help or contact a Poison Control Center immediately.

Patients should be informed to discontinue use and consult a doctor if their child experiences rectal bleeding or does not have a bowel movement after using the product, as these symptoms may indicate a serious condition.

Additionally, healthcare providers should recommend that patients ask a doctor before using any laxative if their child has abdominal pain, nausea, or vomiting; experiences a sudden change in bowel habits lasting more than two weeks; or has already used a laxative for more than one week. This guidance is essential to ensure the safe and effective use of the product.

Storage and Handling

The product is supplied in a tightly sealed container to ensure integrity and stability. It is essential to store the container in a cool, dry place, away from excessive heat to maintain optimal conditions. Proper handling and storage are crucial to preserving the quality of the product.

Additional Clinical Information

No further data are available.

Drug Information (PDF)

This file contains official product information for Glycerin, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)