Glycerin

Description

No description information is available for the specified drug.

Uses and Indications

This drug is indicated for the relief of occasional constipation. It generally produces a bowel movement within 15 minutes to 1 hour after administration.

There are no teratogenic or nonteratogenic effects associated with this product.

Dosage and Administration

For adults and children aged 6 years and older, the recommended dosage is one suppository, or as directed by a healthcare professional. For children aged 2 to under 6 years, it is advised to use child-specific suppositories. The use of this medication is not recommended for children under the age of 2.

The administration of the suppository should be performed by inserting it well up into the rectum. It is important to note that the suppository does not need to melt completely in order to achieve the desired laxative effect.

Contraindications

Use of this product is contraindicated in the following situations:

• Keep out of reach of children to prevent accidental ingestion.

• In the event of accidental swallowing, seek immediate medical assistance or contact a Poison Control Center (1-800-222-1222).

• Discontinue use and consult a healthcare professional if the child experiences rectal bleeding or has not had a bowel movement within 1 hour of using the product.

• Prior to using any laxative, consult a healthcare provider if the child has abdominal pain, nausea, or vomiting; a sudden change in bowel habits lasting more than 2 weeks; or has been using a laxative for more than 1 week.

Warnings and Precautions

For rectal use only, this product may cause rectal discomfort or a burning sensation. Healthcare professionals should advise patients to monitor for these potential side effects.

It is essential to exercise caution when administering this laxative, particularly in pediatric patients. Prior to use, healthcare providers should inquire whether the child has any of the following conditions: abdominal pain, nausea, or vomiting; a sudden change in bowel habits lasting more than two weeks; or if a laxative has already been used for more than one week. These factors may necessitate further evaluation before proceeding with treatment.

Patients should be instructed to discontinue use and consult a healthcare provider if the child experiences rectal bleeding or does not have a bowel movement within one hour of using this product. These symptoms may indicate a serious underlying condition that requires medical attention.

In the event of accidental ingestion, immediate medical assistance should be sought, or the Poison Control Center (1-800-222-1222) should be contacted without delay.

Side Effects

Patients using this product may experience adverse reactions, particularly those related to rectal use. Commonly reported reactions include rectal discomfort and a burning sensation.

It is important for patients to consult a healthcare professional before using this laxative if they have a child with abdominal pain, nausea, or vomiting, a sudden change in bowel habits lasting more than two weeks, or if a laxative has already been used for more than one week.

Patients should discontinue use and seek medical advice if they observe rectal bleeding or if there is no bowel movement within one hour of using the product, as these symptoms may indicate a serious underlying condition.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there is no information available regarding interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Glycerin. Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Pediatric Use

Pediatric patients should be evaluated by a healthcare professional before using any laxative if they present with abdominal pain, nausea, vomiting, a sudden change in bowel habits lasting more than two weeks, or if they have already used a laxative for more than one week.

If a child experiences rectal bleeding or does not have a bowel movement within one hour of using this product, use should be discontinued, and a doctor should be consulted.

For dosing, the recommended single daily dose is as follows: for adults and children aged 6 years and older, one suppository or as directed by a physician; for children aged 2 to under 6 years, Child Suppositories should be used; and the product is not recommended for children under 2 years of age.

It is essential to keep this product out of reach of children. In the event of accidental ingestion, immediate medical assistance should be sought, or the Poison Control Center (1-800-222-1222) should be contacted.

Geriatric Use

Elderly patients may not have specific information regarding the use of this medication, including dosage adjustments, safety concerns, or special precautions. Therefore, healthcare providers should exercise caution when prescribing this medication to geriatric patients. It is advisable to monitor these patients closely for any potential adverse effects or changes in efficacy, given the lack of targeted data for this population.

Pregnancy

There is no specific information available regarding the use of Glycerin suppository during pregnancy. As such, the safety of this medication in pregnant patients has not been established, and there are no known dosage modifications or special precautions recommended for use in this population. Healthcare professionals should consider the lack of data when prescribing this medication to women of childbearing potential and weigh the potential benefits against any unknown risks to fetal outcomes.

Lactation

Lactating mothers are advised to consult a doctor prior to using this product. There is no specific information available regarding the potential for excretion of glycerin suppositories in breast milk or the associated risks to breastfed infants.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the available prescribing information. There are no dosage adjustments, special monitoring requirements, or safety considerations outlined for individuals with reduced kidney function. Healthcare professionals should exercise caution and consider the lack of data when prescribing to this patient population.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

In the event of an overdosage, immediate medical assistance is crucial. If the substance is ingested, healthcare professionals should advise patients or caregivers to seek medical help without delay. It is recommended to contact a Poison Control Center at 1-800-222-1222 for expert guidance.

Prompt intervention is essential to mitigate potential adverse effects associated with overdosage. Symptoms may vary depending on the specific substance involved, and healthcare providers should be prepared to assess and manage these symptoms accordingly.

Management procedures may include supportive care and symptomatic treatment, tailored to the individual patient's needs. Continuous monitoring and evaluation are recommended to ensure patient safety and effective resolution of any complications arising from the overdosage.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the use of the compound in these contexts.

Postmarketing Experience

No postmarketing experience details are available in the insert.

Patient Counseling

Healthcare providers should advise patients to keep this medication out of reach of children to prevent accidental ingestion. Instruct patients that if the product is swallowed, they should seek medical help or contact a Poison Control Center immediately at 1-800-222-1222.

Patients should be informed to stop using the product and consult a doctor if their child experiences rectal bleeding or does not have a bowel movement within one hour of using the product, as these symptoms may indicate a serious condition.

Additionally, healthcare providers should recommend that patients ask a doctor before using any laxative if their child has abdominal pain, nausea, or vomiting; has experienced a sudden change in bowel habits lasting more than two weeks; or has already used a laxative for more than one week. This precaution is essential to ensure the safe and effective use of laxatives in children.

Storage and Handling

The product is supplied in a tightly sealed container to ensure integrity and stability. It is essential to store the container in a cool, dry place, away from excessive heat, to maintain the product's efficacy. Proper handling and storage conditions are crucial for preserving the quality of the product throughout its shelf life.

Additional Clinical Information

No further data are available.

Drug Information (PDF)

This file contains official product information for Glycerin, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)