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Glycerin

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Active ingredient
Glycerin 2.1 g
Other brand names
Drug class
Non-Standardized Chemical Allergen
Dosage form
Suppository
Route
Rectal
Prescription status
OTC (over the counter)
Marketed in the U.S.
Since 2025
Label revision date
October 29, 2025
Active ingredient
Glycerin 2.1 g
Other brand names
Drug class
Non-Standardized Chemical Allergen
Dosage form
Suppository
Route
Rectal
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Marketed in the U.S.
Since 2025
Label revision date
October 29, 2025
Manufacturer
Chain Drug Marketing Association Inc.
Registration number
M007
NDC root
83324-284

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Drug Overview

Glycerin suppositories are a type of medication designed to help relieve occasional constipation. They work by drawing water into the intestines, which helps to soften the stool and stimulate a bowel movement. Typically, you can expect these suppositories to produce results within 15 minutes to 1 hour after use.

These suppositories come in a package of 50 and are distributed by Quality Choice. If you're looking for a gentle and effective way to address constipation, glycerin suppositories may be a suitable option for you.

Uses

If you're experiencing occasional constipation, this product can help provide relief. It typically works quickly, usually producing a bowel movement within 15 minutes to 1 hour after taking it.

You can feel confident using this product, as there are no reported teratogenic effects (which means it doesn't cause birth defects) or nonteratogenic effects (which refer to other types of harmful effects).

Dosage and Administration

When using this medication, you will typically take a single dose each day. For adults and children aged 6 years and older, this means inserting one suppository (a small, solid medication designed to be inserted into the rectum) as directed by your doctor. If you are giving this medication to a child between the ages of 2 and 6, make sure to use the specially formulated Child Suppositories.

To use the suppository, you should insert it well into the rectum. It's important to note that the suppository does not need to melt completely in order to work effectively as a laxative (a medication that helps relieve constipation). Always follow your healthcare provider's instructions for the best results.

What to Avoid

It's important to be cautious when using this product. You should stop using it and consult your doctor if you experience rectal bleeding or if you do not have a bowel movement after using it. Additionally, before using any laxative, it's wise to ask your doctor if you have abdominal pain, nausea, or vomiting, if you've noticed a sudden change in your bowel habits lasting more than two weeks, or if you've already been using a laxative for more than one week.

Taking these precautions can help ensure your safety and well-being while using this product.

Side Effects

You should be aware that this product is intended for rectal use only and may cause some discomfort or a burning sensation in that area. Before using any laxative, it's important to consult with your doctor if you have abdominal pain, nausea, vomiting, a sudden change in bowel habits lasting more than two weeks, or if you have already been using a laxative for more than one week.

If you experience rectal bleeding or do not have a bowel movement after using this product, you should stop using it and consult your doctor, as these symptoms could indicate a more serious condition.

Warnings and Precautions

This product is intended for rectal use only and may cause some discomfort or a burning sensation in that area. It's important to consult your doctor before using any laxative if you experience abdominal pain, nausea, vomiting, a sudden change in your bowel habits lasting more than two weeks, or if you have been using a laxative for more than one week.

You should stop using this product and call your doctor if you notice rectal bleeding or if you do not have a bowel movement after using it, as these could be signs of a more serious condition. If you accidentally swallow the product, seek emergency medical help or contact a Poison Control Center immediately.

Overdose

If you or someone else has swallowed too much of this medication, it’s important to seek medical help immediately. You can do this by contacting a Poison Control Center or going to the nearest emergency room.

Signs of an overdose may include unusual symptoms, but specific details about these symptoms are not provided here. If you notice anything concerning, don’t hesitate to get help. Remember, acting quickly can make a significant difference in ensuring safety and health.

Pregnancy Use

When it comes to using glycerin suppositories during pregnancy, there is currently no specific information available regarding their safety, dosage adjustments, or any special precautions you should take. This means that if you are pregnant or planning to become pregnant, it’s important to consult with your healthcare provider before using glycerin suppositories. They can help you understand any potential risks and determine the best course of action for your situation. Always prioritize your health and the health of your baby by seeking professional advice.

Lactation Use

If you are a nursing mother, you can use glycerin suppositories without specific warnings or recommendations against their use. Currently, there is no information indicating that glycerin is passed into breast milk or that it poses any risk to your infant. This means you can feel more at ease while managing your health during breastfeeding. Always consult with your healthcare provider if you have any concerns or questions about medications while nursing.

Pediatric Use

It's important to keep this medication out of reach of children to prevent accidental ingestion. If a child swallows it, seek medical help or contact a Poison Control Center immediately.

For dosing, adults and children aged 6 years and older can use one suppository, or follow your doctor's instructions. For children aged 2 to under 6 years, make sure to use the Child Suppositories specifically designed for their age group. Always follow the directions carefully to ensure safety and effectiveness.

Geriatric Use

While there is no specific information available about the use of this medication in older adults, it’s important to approach any new treatment with caution. If you or a loved one is an older adult, always consult with a healthcare provider before starting a new medication. They can help assess any potential risks and ensure that the treatment is safe and appropriate for your individual health needs.

Remember, older adults may have different responses to medications, so discussing any concerns or existing health conditions with your doctor is essential for safe and effective care.

Renal Impairment

If you have kidney problems, it's important to know that the information provided does not include specific guidelines for dosage adjustments, special monitoring, or safety considerations related to renal impairment (kidney issues). This means that there are no tailored recommendations for how your treatment may need to change based on your kidney function.

Always consult your healthcare provider for personalized advice and to ensure that your treatment is safe and effective, especially if you have any concerns about your kidney health.

Hepatic Impairment

If you have liver problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or precautions for your condition. This means that there are no tailored guidelines for how this medication may affect you if you have hepatic impairment (liver issues).

Always consult your healthcare provider for personalized advice and to discuss any concerns regarding your liver health and how it may relate to your treatment. They can help ensure that you receive the safest and most effective care.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you. Always share your full list of medications and any health concerns during your appointments to receive the best care possible.

Storage and Handling

To ensure the safety and effectiveness of your product, always store the container tightly closed. This helps protect the contents from contamination and maintains their quality. Additionally, keep the product away from excessive heat, as high temperatures can negatively impact its performance.

When handling the product, be mindful of these storage guidelines to ensure you are using it safely and effectively. Proper storage not only preserves the product but also contributes to your overall safety during use.

Additional Information

No further information is available.

FAQ

What are Glycerin Suppositories used for?

Glycerin Suppositories are used for the relief of occasional constipation.

How quickly do Glycerin Suppositories work?

This product generally produces a bowel movement in 1/4 to 1 hour.

What is the recommended dosage for adults and children over 6?

Adults and children 6 years and over should use 1 suppository, or as directed by a doctor.

What should I do if I experience rectal bleeding?

You should stop using Glycerin Suppositories and consult a doctor, as this may indicate a serious condition.

Can I use Glycerin Suppositories if I have abdominal pain?

You should ask a doctor before using any laxative if you have abdominal pain, nausea, or vomiting.

How should I administer Glycerin Suppositories?

Insert the suppository well up into the rectum for it to work effectively.

Are there any warnings associated with Glycerin Suppositories?

Yes, they are for rectal use only and may cause rectal discomfort or a burning sensation.

What should I do if I swallow Glycerin Suppositories?

If swallowed, get medical help or contact a Poison Control Center right away.

Is there any information about using Glycerin Suppositories during pregnancy?

There is no specific information regarding the use of glycerin suppositories during pregnancy in the provided text.

How should I store Glycerin Suppositories?

Store the container tightly closed and keep it away from excessive heat.

Packaging Info

Below are the non-prescription pack sizes of Glycerin. Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Glycerin.
Details

Drug Information (PDF)

This file contains official product information for Glycerin, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the drug.

Uses and Indications

This drug is indicated for the relief of occasional constipation. It generally produces a bowel movement within 15 minutes to 1 hour after administration.

Limitations of Use: There are no known teratogenic or nonteratogenic effects associated with this product.

Dosage and Administration

Adults and children aged 6 years and older are recommended to administer a single daily dosage of 1 suppository, or as directed by a healthcare professional. For children aged 2 to under 6 years, Child Suppositories should be utilized as per the dosing guidelines.

The route of administration involves inserting the suppository well up into the rectum. It is important to note that the suppository does not need to melt completely in order to produce the desired laxative effect.

Contraindications

Use of this product is contraindicated in patients experiencing rectal bleeding or those who have not had a bowel movement after using this product.

Consult a healthcare professional prior to use if the patient has abdominal pain, nausea, or vomiting; a sudden change in bowel habits lasting more than two weeks; or if a laxative has been used for more than one week.

Warnings and Precautions

For rectal use only, this product may cause rectal discomfort or a burning sensation. Healthcare professionals should advise patients to exercise caution and consider the following general precautions before recommending this laxative.

Patients should be instructed to consult a doctor prior to use if they experience any of the following conditions: abdominal pain, nausea, or vomiting; a sudden change in bowel habits lasting more than two weeks; or if they have already used a laxative for more than one week. These conditions may necessitate further evaluation to rule out underlying issues.

Patients must be advised to discontinue use and seek medical attention if they experience rectal bleeding or if there is no bowel movement after using this product. These symptoms may indicate a serious condition that requires immediate medical intervention.

In the event of accidental ingestion, patients should be instructed to seek emergency medical help or contact a Poison Control Center without delay. Prompt action is essential to ensure patient safety in such situations.

Side Effects

Patients using this product should be aware that it is intended for rectal use only. Common adverse reactions may include rectal discomfort or a burning sensation.

Participants are advised to consult a healthcare professional before using any laxative if they experience abdominal pain, nausea, or vomiting, have a sudden change in bowel habits lasting more than two weeks, or if they have already used a laxative for more than one week.

In the event of rectal bleeding or if there is no bowel movement after using this product, patients should discontinue use and seek medical advice, as these symptoms may indicate a serious condition.

Drug Interactions

There are currently no documented drug interactions associated with the use of this medication. Additionally, there is no information available regarding interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Glycerin. Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Glycerin.
Details

Pediatric Use

Pediatric patients should be kept out of reach of children. In the event of accidental ingestion, immediate medical assistance or contact with a Poison Control Center is advised.

For dosing, adults and children aged 6 years and older may use 1 suppository, or as directed by a healthcare professional. For children aged 2 to under 6 years, Child Suppositories are recommended.

Geriatric Use

Elderly patients may not have specific information regarding the use of this medication, including dosage adjustments, safety concerns, or special precautions. Therefore, healthcare providers should exercise caution when prescribing this medication to geriatric patients. It is advisable to monitor these patients closely for any potential adverse effects or changes in therapeutic response, given the lack of targeted data for this population.

Pregnancy

There is no specific information available regarding the use of glycerin suppositories during pregnancy, including safety concerns, dosage modifications, or special precautions. Healthcare professionals should consider the lack of data when advising pregnant patients and weigh the potential benefits against any unknown risks. Women of childbearing potential should be counseled accordingly, and alternative treatments may be considered if necessary.

Lactation

There are no specific warnings or recommendations regarding the use of glycerin suppositories in lactating mothers. Additionally, there are no statements concerning the potential for excretion of glycerin in breast milk or any associated risks to breastfed infants.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the available prescribing information. There are no dosage adjustments, special monitoring requirements, or safety considerations outlined for individuals with reduced kidney function. Healthcare professionals should exercise caution and consider the lack of data when prescribing to this patient population.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

In the event of an overdosage, immediate medical intervention is crucial. If the substance is ingested, it is imperative to seek medical assistance or contact a Poison Control Center without delay.

Healthcare professionals should be aware that prompt action can significantly influence the outcome of an overdosage situation. Symptoms may vary depending on the specific substance involved, and monitoring for any adverse effects is essential.

Management of overdosage should include supportive care and symptomatic treatment as necessary. Continuous assessment of the patient's condition is recommended to address any complications that may arise.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the use of the compound in these contexts.

Postmarketing Experience

No postmarketing experience details are available in the insert text.

Patient Counseling

Patients should be advised to seek immediate medical assistance or contact a Poison Control Center if the product is swallowed. It is important for healthcare providers to instruct patients to discontinue use and consult a doctor if they experience rectal bleeding or if there is no bowel movement after using the product, as these symptoms may indicate a serious condition.

Additionally, patients should be encouraged to ask their doctor before using any laxative if they have abdominal pain, nausea, or vomiting, if they have experienced a sudden change in bowel habits lasting more than two weeks, or if they have already used a laxative for more than one week. This guidance is crucial to ensure the safe and effective use of the product.

Storage and Handling

The product is supplied in a tightly sealed container to ensure integrity and stability. It is essential to store the container in a cool, dry place, away from excessive heat to maintain optimal conditions. Proper handling includes ensuring that the container remains tightly closed when not in use to prevent contamination and degradation of the product.

Additional Clinical Information

No further data are available.

Drug Information (PDF)

This file contains official product information for Glycerin, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Glycerin, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.