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Glycerin

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Active ingredient
Glycerin 2.1 g
Other brand names
Drug class
Non-Standardized Chemical Allergen
Dosage form
Suppository
Route
Rectal
Prescription status
OTC (over the counter)
Marketed in the U.S.
Since 2012
Label revision date
October 24, 2025
Active ingredient
Glycerin 2.1 g
Other brand names
Drug class
Non-Standardized Chemical Allergen
Dosage form
Suppository
Route
Rectal
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Marketed in the U.S.
Since 2012
Label revision date
October 24, 2025
Manufacturer
DSC Laboratories Inc.
Registration number
M007
NDC root
52316-723

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Drug Overview

Glycerin suppositories are a type of medication used to relieve occasional constipation. They work by drawing water into the intestines, which helps to soften the stool and stimulate a bowel movement. Typically, you can expect these suppositories to produce results within 15 minutes to 1 hour after use.

These suppositories come in a package of 50 and are designed for easy use when you need quick relief from constipation.

Uses

If you're experiencing occasional constipation, this product can help provide relief. It typically works quickly, usually producing a bowel movement within 15 minutes to 1 hour after taking it. This makes it a convenient option when you need fast relief from discomfort.

Dosage and Administration

When using this medication, you will typically take a single dose each day. For adults and children aged 6 years and older, this means inserting one suppository (a small, solid medication designed to be inserted into the rectum) as directed by your doctor. If you are giving this medication to a child between the ages of 2 and 6, make sure to use the specially formulated Child Suppositories.

To use the suppository, you should insert it well up into the rectum. It's important to note that the suppository does not need to melt completely in order to work effectively as a laxative (a medication that helps relieve constipation). Always follow your healthcare provider's instructions for the best results.

What to Avoid

It's important to be cautious when using this product. You should stop using it and consult your doctor if you experience rectal bleeding or if you do not have a bowel movement after using it. Additionally, before using any laxative, it's wise to ask your doctor if you have abdominal pain, nausea, or vomiting, if you've noticed a sudden change in your bowel habits lasting more than two weeks, or if you've already been using a laxative for more than one week.

Taking these precautions can help ensure your safety and well-being while using this product.

Side Effects

Using this product may lead to some discomfort, such as a burning sensation in the rectal area. It's important to remember that this medication is intended for rectal use only.

Before using any laxative, you should consult your doctor if you experience abdominal pain, nausea, or vomiting, have had a sudden change in bowel habits lasting more than two weeks, or if you have already been using a laxative for more than one week. If you notice rectal bleeding or do not have a bowel movement after using this product, stop using it and seek medical advice, as these could be signs of a more serious condition.

Warnings and Precautions

This product is intended for rectal use only and may cause some discomfort or a burning sensation in the area. Before using any laxative, it’s important to consult your doctor if you have abdominal pain, nausea, vomiting, a sudden change in your bowel habits lasting more than two weeks, or if you have already been using a laxative for more than a week.

You should stop using this product and call your doctor if you experience rectal bleeding or if you do not have a bowel movement after using it, as these symptoms could indicate a more serious condition. If the product is swallowed, seek emergency medical help or contact a Poison Control Center immediately.

Overdose

If you or someone else has swallowed too much of this medication, it’s important to seek medical help immediately. You can do this by contacting a Poison Control Center or going to the nearest emergency room.

Signs of an overdose can vary, but they may include unusual drowsiness, confusion, or difficulty breathing. If you notice any of these symptoms, don’t hesitate to get help right away. Remember, acting quickly can make a significant difference in ensuring safety and health.

Pregnancy Use

When considering the use of glycerin suppositories during pregnancy, it's important to note that there is no specific information available regarding their safety, dosage adjustments, or any special precautions for pregnant individuals. This means that the effects of glycerin suppositories on pregnancy have not been clearly studied or established.

If you are pregnant or planning to become pregnant, it's always best to consult with your healthcare provider before using any medication, including glycerin suppositories, to ensure the safety of you and your baby.

Lactation Use

If you are breastfeeding and considering the use of glycerin suppositories, it’s important to consult your doctor first. Currently, there is no specific information available about whether glycerin is passed into breast milk or the potential risks it may pose to your nursing infant. Your healthcare provider can help you weigh the benefits and any possible concerns to ensure the safety of both you and your baby.

Pediatric Use

It's important to keep this medication out of reach of children to prevent accidental ingestion. If a child swallows it, seek medical help or contact a Poison Control Center immediately.

For dosing, adults and children aged 6 years and older can use one suppository, or follow your doctor's instructions. For children aged 2 to under 6 years, make sure to use the Child Suppositories specifically designed for their age group. Always consult with a healthcare professional if you have any questions or concerns about using this medication for your child.

Geriatric Use

When it comes to using this medication in older adults, there is no specific information available about dosage adjustments, safety concerns, or special precautions. This means that if you or a loved one is an older adult, it’s important to consult with a healthcare provider before starting the medication. They can help determine the best approach based on individual health needs and any other medications being taken. Always prioritize open communication with your healthcare team to ensure safe and effective treatment.

Renal Impairment

If you have kidney problems, it's important to know that the information provided does not include specific guidelines for dosage adjustments, special monitoring, or safety considerations related to renal impairment (kidney issues). This means that there are no tailored recommendations for how your treatment may need to change based on your kidney function.

Always consult your healthcare provider for personalized advice and to ensure that your treatment plan is safe and effective for your specific situation. They can help monitor your kidney health and make any necessary adjustments to your medications.

Hepatic Impairment

If you have liver problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or precautions for your condition. This means that there are no tailored guidelines for how this medication may affect you if you have hepatic impairment (liver issues).

Before starting any new medication, including this one, you should discuss your liver health with your healthcare provider. They can help determine the best approach for your treatment and ensure your safety.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you. Always share your complete list of medications and any health conditions you have to receive the best care possible.

Storage and Handling

To ensure the best performance and safety of your product, always store the container tightly closed. This helps protect the contents from contamination and maintains their effectiveness. Additionally, keep the product away from excessive heat, as high temperatures can compromise its quality.

When handling the product, be mindful of these storage guidelines to ensure it remains safe and effective for use. If you have any specific disposal instructions, please follow those carefully to maintain safety and environmental standards.

Additional Information

No further information is available.

FAQ

What are Glycerin Suppositories used for?

Glycerin Suppositories are used for the relief of occasional constipation.

How quickly do Glycerin Suppositories work?

This product generally produces a bowel movement in 1/4 to 1 hour.

What is the recommended dosage for adults and children over 6?

Adults and children 6 years and over should use 1 suppository, or as directed by a doctor.

What should I do if I experience rectal bleeding?

You should stop using Glycerin Suppositories and consult a doctor, as this may indicate a serious condition.

Are there any contraindications for using Glycerin Suppositories?

No specific contraindications are explicitly stated in the provided information.

Can I use Glycerin Suppositories if I have abdominal pain?

You should ask a doctor before using any laxative if you have abdominal pain, nausea, or vomiting.

What should I do if I swallow Glycerin Suppositories?

If swallowed, get medical help or contact a Poison Control Center right away.

Is it safe to use Glycerin Suppositories during pregnancy?

There is no specific information regarding the use of glycerin suppositories during pregnancy in the provided text.

What precautions should nursing mothers take?

Nursing mothers should consult a doctor before using glycerin suppositories.

How should Glycerin Suppositories be stored?

Store the container tightly closed and keep it away from excessive heat.

Packaging Info

Below are the non-prescription pack sizes of Glycerin. Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Glycerin.
Details

Drug Information (PDF)

This file contains official product information for Glycerin, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the specified drug.

Uses and Indications

This drug is indicated for the relief of occasional constipation. It is designed to produce a bowel movement typically within 15 minutes to 1 hour after administration.

There are no teratogenic or nonteratogenic effects associated with this product.

Dosage and Administration

For adults and children aged 6 years and older, the recommended dosage is one suppository administered once daily, or as directed by a healthcare professional. For children aged 2 to under 6 years, it is advised to use Child Suppositories specifically formulated for this age group.

The route of administration involves inserting the suppository well up into the rectum. It is important to note that the suppository does not need to melt completely in order to produce the desired laxative effect.

Contraindications

Use of this product is contraindicated in patients experiencing rectal bleeding or those who do not have a bowel movement after using the product. Additionally, consultation with a healthcare professional is advised prior to use in individuals with abdominal pain, nausea, or vomiting; a sudden change in bowel habits lasting more than two weeks; or those who have already used a laxative for more than one week.

Warnings and Precautions

For rectal use only, this product may cause rectal discomfort or a burning sensation.

Healthcare professionals should advise patients to consult a doctor before using any laxative if they experience abdominal pain, nausea, or vomiting. Additionally, patients should seek medical advice if they notice a sudden change in bowel habits lasting more than two weeks or if they have already used a laxative for more than one week.

Patients are instructed to stop using the product and contact their doctor if they experience rectal bleeding or if there is no bowel movement after use. These symptoms may indicate a serious underlying condition that requires further evaluation.

In cases of accidental ingestion, it is imperative to seek emergency medical assistance or contact a Poison Control Center immediately.

Side Effects

Patients using this product should be aware of several important warnings and potential adverse reactions. This product is intended for rectal use only and may cause rectal discomfort or a burning sensation in some individuals.

Before using any laxative, patients are advised to consult a healthcare professional if they experience abdominal pain, nausea, or vomiting, have a sudden change in bowel habits lasting more than two weeks, or if they have already used a laxative for more than one week.

Patients should discontinue use and seek medical advice if they experience rectal bleeding or if there is no bowel movement after using this product. These symptoms may indicate a serious underlying condition that requires further evaluation.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there are no known interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Glycerin. Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Glycerin.
Details

Pediatric Use

Pediatric patients should be kept out of reach of children. In the event of accidental ingestion, immediate medical assistance or contact with a Poison Control Center is advised.

For dosing, adults and children aged 6 years and older may use 1 suppository, or as directed by a healthcare professional. For children aged 2 to under 6 years, Child Suppositories are recommended.

Geriatric Use

Elderly patients may not have specific information regarding the use of this medication, including dosage adjustments, safety concerns, or special precautions. Therefore, healthcare providers should exercise caution when prescribing this medication to geriatric patients. It is advisable to monitor these patients closely for any adverse effects or changes in therapeutic response, given the lack of targeted data for this population.

Pregnancy

There is no specific information available regarding the use of glycerin suppositories during pregnancy, including safety concerns, dosage modifications, or special precautions. Healthcare professionals should consider the lack of data when advising pregnant patients and weigh the potential benefits against any unknown risks. It is recommended that women of childbearing potential discuss their individual circumstances with their healthcare provider before using glycerin suppositories.

Lactation

Nursing mothers are advised to consult a doctor prior to using glycerin suppositories. Currently, there is no specific information available regarding the potential for excretion of glycerin in breast milk or any associated risks to breastfed infants from the use of glycerin suppositories in lactating mothers.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the available prescribing information. There are no dosage adjustments, special monitoring requirements, or safety considerations outlined for individuals with reduced kidney function. Healthcare professionals should exercise caution and consider the lack of data when prescribing to this patient population.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the prescribing information.

Overdosage

In the event of an overdosage, immediate medical intervention is crucial. If the substance is ingested, it is imperative to seek medical assistance or contact a Poison Control Center without delay.

Healthcare professionals should be aware that prompt action can significantly influence the outcome of an overdosage situation. Symptoms may vary depending on the specific substance involved, and it is essential to monitor the patient closely for any signs of adverse reactions.

Management of overdosage should be guided by the clinical presentation and may include supportive care and symptomatic treatment as necessary. It is recommended that healthcare providers follow established protocols for the management of poisoning and overdose cases, ensuring that appropriate measures are taken to mitigate potential risks to the patient.

Nonclinical Toxicology

No information is available regarding teratogenic or non-teratogenic effects. Additionally, there is no data provided concerning nonclinical toxicology, animal pharmacology, or toxicology.

Postmarketing Experience

No postmarketing experience details are available in the insert text.

Patient Counseling

Healthcare providers should advise patients to seek immediate medical assistance or contact a Poison Control Center if the product is swallowed. It is important to inform patients that they should discontinue use and consult a doctor if they experience rectal bleeding or do not have a bowel movement after using the product, as these symptoms may indicate a serious condition.

Additionally, healthcare providers should encourage patients to ask a doctor before using any laxative if they have abdominal pain, nausea, or vomiting, if they have experienced a sudden change in bowel habits lasting more than two weeks, or if they have already used a laxative for more than one week. This guidance is essential to ensure patient safety and appropriate use of the product.

Storage and Handling

The product is supplied in a tightly sealed container to ensure integrity and stability. It is essential to store the container in a cool, dry place, away from excessive heat to maintain optimal conditions. Proper handling includes keeping the container tightly closed when not in use to prevent contamination and degradation of the product.

Additional Clinical Information

No further data are available.

Drug Information (PDF)

This file contains official product information for Glycerin, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Glycerin, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

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Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.