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Glycerin

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Active ingredient
Glycerin 2 g
Other brand names
Drug class
Non-Standardized Chemical Allergen
Dosage form
Suppository
Route
Rectal
Prescription status
OTC (over the counter)
Marketed in the U.S.
Since 2016
Label revision date
October 24, 2025
Active ingredient
Glycerin 2 g
Other brand names
Drug class
Non-Standardized Chemical Allergen
Dosage form
Suppository
Route
Rectal
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Marketed in the U.S.
Since 2016
Label revision date
October 24, 2025
Manufacturer
H E B
Registration number
M007
NDC root
37808-398

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Drug Overview

Glycerin suppositories are a type of medication designed to help relieve occasional constipation. They work by drawing water into the intestines, which helps to soften the stool and stimulate a bowel movement. Typically, you can expect to have a bowel movement within 15 minutes to 1 hour after using them.

These suppositories come in a package of 50 and are intended for adult use. If you're experiencing occasional constipation, glycerin suppositories may provide a gentle and effective solution to help you feel more comfortable.

Uses

If you're experiencing occasional constipation, this product can help provide relief. It typically works quickly, usually producing a bowel movement within 15 minutes to 1 hour after taking it. This makes it a convenient option when you need fast relief from discomfort.

Dosage and Administration

If you or your child are using this medication, it's important to know how to take it properly. For adults and children aged 6 years and older, the typical dose is one suppository, or as your doctor advises. If your child is between 2 and 6 years old, make sure to use the specially formulated Child Suppositories.

To use the suppository, you will need to insert it well into the rectum. Don't worry if the suppository doesn't melt completely; it can still work effectively as a laxative (a medication that helps relieve constipation). You should only need to take this medication once a day. Always follow your healthcare provider's instructions for the best results.

What to Avoid

It's important to be cautious when using this product. You should stop using it and consult your doctor if you experience rectal bleeding or if you do not have a bowel movement after using it. Additionally, before using any laxative, it's wise to ask your doctor if you have abdominal pain, nausea, or vomiting, if you've noticed a sudden change in your bowel habits lasting more than two weeks, or if you've already been using a laxative for more than one week.

Taking these precautions can help ensure your safety and well-being while using this product.

Side Effects

Using this product may lead to some discomfort, such as rectal discomfort or a burning sensation, as it is intended for rectal use only. It's important to consult your doctor before using any laxative if you experience abdominal pain, nausea, vomiting, a sudden change in bowel habits lasting more than two weeks, or if you have already used a laxative for more than one week.

You should stop using the product and seek medical advice if you notice rectal bleeding or if you do not have a bowel movement after using it, as these symptoms could indicate a more serious condition.

Warnings and Precautions

This product is intended for rectal use only and may cause some discomfort or a burning sensation. Before using any laxative, it’s important to consult your doctor if you have abdominal pain, nausea, vomiting, a sudden change in your bowel habits lasting more than two weeks, or if you have already been using a laxative for more than one week.

You should stop using this product and call your doctor if you experience rectal bleeding or if you do not have a bowel movement after using it, as these symptoms could indicate a more serious condition. If the product is swallowed, seek emergency medical help or contact a Poison Control Center immediately.

Overdose

If you or someone else has swallowed too much of a medication, it’s important to seek medical help immediately. You can do this by contacting a Poison Control Center or going to the nearest emergency room. Acting quickly can make a significant difference in the outcome.

Signs of an overdose can vary, but they may include unusual drowsiness, confusion, or difficulty breathing. If you notice any of these symptoms, don’t hesitate to get help right away. Remember, it’s always better to be safe and seek assistance if you suspect an overdose.

Pregnancy Use

When considering the use of Glycerin suppositories during pregnancy, it's important to note that there is no specific information available about their safety, dosage adjustments, or any special precautions for pregnant individuals. This means that the effects of these suppositories on pregnancy have not been studied or documented in the drug insert.

If you are pregnant or planning to become pregnant, it is always best to consult with your healthcare provider before using any medication, including over-the-counter products like Glycerin suppositories. Your doctor can provide guidance tailored to your individual health needs and circumstances.

Lactation Use

If you are breastfeeding, it's important to talk to your doctor before using glycerin suppositories. Currently, there is no specific information available about whether these suppositories can pass into breast milk or what risks they might pose to your baby. Consulting with a healthcare professional can help ensure that you make the safest choice for both you and your infant.

Pediatric Use

When it comes to using this medication for children, it's important to follow specific guidelines. For children aged 2 to under 6 years, you should use Child Suppositories. For those 6 years and older, one suppository can be used, or you can follow your doctor's instructions.

Always remember to keep this medication out of reach of children. If a child accidentally swallows it, seek medical help or contact a Poison Control Center immediately. Your child's safety is the top priority, so adhering to these recommendations is crucial.

Geriatric Use

When it comes to using this medication in older adults, there is no specific information available about dosage adjustments, safety concerns, or special precautions. This means that if you or a loved one is an older adult, it’s important to consult with a healthcare provider for personalized advice. They can help determine the best approach based on individual health needs and any other medications being taken. Always prioritize open communication with your healthcare team to ensure safe and effective treatment.

Renal Impairment

If you have kidney problems, it's important to know that there are no specific guidelines or dosage adjustments mentioned for your condition in the available information. This means that the usual recommendations for monitoring or safety considerations related to renal impairment (kidney issues) are not provided.

Always consult your healthcare provider for personalized advice and to ensure that any medications you take are safe and appropriate for your kidney health. They can help you understand how your condition may affect your treatment plan.

Hepatic Impairment

If you have liver problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or precautions for your condition. This means that there are no tailored guidelines for how this medication may affect you differently due to your liver health.

Always consult your healthcare provider for personalized advice and to discuss any concerns you may have regarding your liver function and how it relates to your treatment. They can help ensure that your medication is safe and effective for you.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you. Always share your complete list of medications and any recent lab tests to avoid any potential issues. Your health and safety should always come first.

Storage and Handling

To ensure the safety and effectiveness of your product, always store the container tightly closed. This helps protect the contents from contamination and maintains their quality. Additionally, keep the product away from excessive heat, as high temperatures can compromise its integrity.

When handling the product, be mindful of these storage guidelines to ensure optimal performance and safety. If you have any questions about disposal or specific usage instructions, please refer to the accompanying materials or consult a professional.

Additional Information

No further information is available.

FAQ

What is Glycerin Suppositories used for?

Glycerin Suppositories are used for the relief of occasional constipation.

How quickly do Glycerin Suppositories work?

This product generally produces a bowel movement in 1/4 to 1 hour.

What is the recommended dosage for adults?

Adults and children 6 years and over should use 1 suppository, or as directed by a doctor.

What should I do if I experience rectal bleeding?

You should stop using Glycerin Suppositories and consult a doctor, as this may indicate a serious condition.

Can children use Glycerin Suppositories?

Children 2 to under 6 years should use Child Suppositories, while those 6 years and over can use the adult version.

What precautions should I take before using Glycerin Suppositories?

Ask a doctor before using if you have abdominal pain, nausea, vomiting, or a sudden change in bowel habits lasting more than 2 weeks.

What should I do if I swallow Glycerin Suppositories?

If swallowed, get medical help or contact a Poison Control Center right away.

Are there any warnings associated with Glycerin Suppositories?

Yes, they are for rectal use only and may cause rectal discomfort or a burning sensation.

Is it safe to use Glycerin Suppositories during pregnancy?

There is no specific information provided regarding the use of Glycerin Suppositories during pregnancy.

What should nursing mothers do before using Glycerin Suppositories?

Nursing mothers should consult a doctor before using this product.

Packaging Info

Below are the non-prescription pack sizes of Glycerin. Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Glycerin.
Details

Drug Information (PDF)

This file contains official product information for Glycerin, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the specified drug.

Uses and Indications

This drug is indicated for the relief of occasional constipation. It generally produces a bowel movement within 15 minutes to 1 hour after administration.

There are no teratogenic or nonteratogenic effects associated with this product.

Dosage and Administration

Adults and children aged 6 years and older are advised to administer 1 suppository, or as directed by a healthcare professional. For children aged 2 to under 6 years, Child Suppositories should be utilized.

The route of administration is rectal. The suppository should be inserted well up into the rectum. It is important to note that the suppository does not need to melt completely in order to achieve the desired laxative effect.

The recommended frequency of administration is a single daily dose.

Contraindications

Use of this product is contraindicated in patients experiencing rectal bleeding or those who do not have a bowel movement after using the product. Additionally, consultation with a healthcare professional is advised prior to use in individuals with abdominal pain, nausea, or vomiting, as well as those who have experienced a sudden change in bowel habits lasting more than two weeks or who have already used a laxative for more than one week.

Warnings and Precautions

For rectal use only, this product may cause rectal discomfort or a burning sensation.

Healthcare professionals should advise patients to consult a doctor prior to using any laxative if they experience abdominal pain, nausea, or vomiting; if there is a sudden change in bowel habits lasting more than two weeks; or if they have already used a laxative for more than one week.

Patients should be instructed to discontinue use and seek medical advice if they experience rectal bleeding or if there is no bowel movement after using this product, as these symptoms may indicate a serious underlying condition.

In cases of accidental ingestion, it is imperative to seek emergency medical assistance or contact a Poison Control Center immediately.

Side Effects

Patients using this product should be aware that it is intended for rectal use only and may cause rectal discomfort or a burning sensation.

Before using any laxative, patients are advised to consult a healthcare professional if they experience abdominal pain, nausea, or vomiting, have a sudden change in bowel habits lasting more than two weeks, or have already used a laxative for more than one week.

Patients should discontinue use and seek medical advice if they experience rectal bleeding or if there is no bowel movement after using this product, as these symptoms may indicate a serious underlying condition.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there is no information available regarding interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Glycerin. Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Glycerin.
Details

Pediatric Use

Pediatric patients aged 2 to under 6 years should be administered Child Suppositories. For patients 6 years and older, the recommended dosage is 1 suppository, or as directed by a healthcare professional.

It is crucial to keep this medication out of reach of children. In the event of accidental ingestion, immediate medical assistance should be sought, or contact a Poison Control Center without delay.

Geriatric Use

Elderly patients may not have specific information regarding the use of this medication, including dosage adjustments, safety concerns, or special precautions. Therefore, healthcare providers should exercise caution when prescribing this medication to geriatric patients. It is advisable to monitor these patients closely for any adverse effects or changes in efficacy, given the lack of targeted data for this population.

Pregnancy

There is no information available regarding the use of Glycerin suppositories during pregnancy, including safety concerns, dosage modifications, or any special precautions that should be taken. Healthcare professionals should consider the lack of data when advising pregnant patients and weigh the potential risks and benefits of using this medication in this population. Women of childbearing potential should be counseled accordingly.

Lactation

Lactating mothers are advised to consult a doctor prior to using this product. There is no specific information available regarding the potential for excretion of glycerin suppositories in breast milk or the associated risks to breastfed infants.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the available data regarding dosage adjustments, special monitoring, or safety considerations. Therefore, healthcare professionals should exercise caution when prescribing this medication to patients with reduced kidney function, as the lack of information necessitates careful clinical judgment and monitoring.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

In the event of an overdosage, immediate medical assistance is crucial. If the substance is ingested, healthcare professionals should advise patients or caregivers to seek medical help or contact a Poison Control Center without delay.

Prompt intervention is essential to mitigate potential adverse effects associated with overdosage. Symptoms may vary depending on the specific substance involved, and healthcare providers should be prepared to assess and manage these symptoms accordingly.

Management procedures may include supportive care and symptomatic treatment, tailored to the individual patient's needs. Continuous monitoring and evaluation are recommended to ensure patient safety and effective resolution of any complications arising from the overdosage.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data in these areas limits the understanding of the compound's potential effects in nonclinical settings.

Postmarketing Experience

No postmarketing experience details are available in the insert.

Patient Counseling

Healthcare providers should advise patients to keep this medication out of reach of children to prevent accidental ingestion. In the event of swallowing the product, patients should seek medical assistance or contact a Poison Control Center immediately.

Patients should be instructed to discontinue use and consult a doctor if they experience rectal bleeding or if there is no bowel movement after using the product, as these symptoms may indicate a serious condition.

Additionally, healthcare providers should recommend that patients ask a doctor before using any laxative if they have abdominal pain, nausea, or vomiting; if they have experienced a sudden change in bowel habits lasting more than two weeks; or if they have already used a laxative for more than one week. This precaution is essential to ensure the safe and effective use of the medication.

Storage and Handling

The product is supplied in a tightly sealed container to ensure integrity and stability. It is essential to store the container in a cool, dry place, away from excessive heat to maintain optimal conditions. Proper handling and storage are crucial to preserving the quality of the product.

Additional Clinical Information

No further data are available.

Drug Information (PDF)

This file contains official product information for Glycerin, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Glycerin, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.