Glycerin

Description

No description information is available for the drug.

Uses and Indications

This drug is indicated for the relief of occasional constipation. It generally produces a bowel movement within 15 minutes to 1 hour after administration.

There are no known teratogenic or nonteratogenic effects associated with this product.

Dosage and Administration

For adults and children aged 6 years and older, the recommended dosage is one suppository administered once daily, or as directed by a healthcare professional. For children aged 2 to under 6 years, it is advised to use Child Suppositories specifically formulated for this age group.

The route of administration involves inserting the suppository well up into the rectum. It is important to note that the suppository does not need to melt completely in order to achieve the desired laxative effect.

Contraindications

Use of this product is contraindicated in patients experiencing rectal bleeding or those who have not had a bowel movement after using this product.

Consult a healthcare professional prior to use if the patient has abdominal pain, nausea, or vomiting; a sudden change in bowel habits lasting more than two weeks; or if a laxative has been used for more than one week.

Warnings and Precautions

For rectal use only. Patients may experience rectal discomfort or a burning sensation following administration.

Healthcare professionals should advise patients to consult a physician prior to using any laxative if they present with abdominal pain, nausea, or vomiting; experience a sudden change in bowel habits lasting more than two weeks; or have already utilized a laxative for more than one week.

Patients are instructed to discontinue use and seek medical advice if they encounter rectal bleeding or do not achieve a bowel movement after using this product, as these symptoms may indicate a serious underlying condition.

In the event of accidental ingestion, immediate medical assistance should be sought, or the local Poison Control Center should be contacted without delay.

Side Effects

Patients using this product should be aware that it is intended for rectal use only. Common adverse reactions may include rectal discomfort or a burning sensation.

Participants are advised to consult a healthcare professional before using any laxative if they experience abdominal pain, nausea, or vomiting, have a sudden change in bowel habits lasting more than two weeks, or have already used a laxative for more than one week.

In the event of rectal bleeding or failure to achieve a bowel movement after using this product, patients should discontinue use and seek medical advice, as these symptoms may indicate a serious underlying condition.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there is no information available regarding interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Glycerin. Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Pediatric Use

Pediatric patients should be advised to keep this medication out of reach of children. In the event of accidental ingestion, immediate medical assistance or contact with a Poison Control Center is recommended.

For dosing, the following guidelines apply:

• For adults and children aged 6 years and older, the recommended dosage is 1 suppository daily, or as directed by a healthcare professional.

• For children aged 2 to under 6 years, Child Suppositories should be used as per the provided directions.

Healthcare professionals should ensure that caregivers are aware of these dosing instructions and the importance of supervision to prevent accidental ingestion.

Geriatric Use

Elderly patients may not have specific information regarding the use of this medication, including dosage adjustments, safety concerns, or special precautions. Therefore, healthcare providers should exercise caution when prescribing this medication to geriatric patients. It is advisable to monitor these patients closely for any potential adverse effects or changes in efficacy, given the lack of targeted data for this population.

Pregnancy

There is no specific information available regarding the use of glycerin suppositories during pregnancy, including safety concerns, dosage modifications, or special precautions. Healthcare professionals should consider the lack of data when advising pregnant patients and weigh the potential benefits against any unknown risks. It is recommended that women of childbearing potential discuss their individual circumstances with their healthcare provider before using glycerin suppositories.

Lactation

There are no specific warnings or considerations regarding the use of glycerin suppositories in lactating mothers. The available data does not indicate any known effects on breastfed infants. Therefore, healthcare professionals may consider the use of glycerin suppositories in lactating mothers without specific concerns related to nursing or lactation.

Renal Impairment

Patients with renal impairment may not have specific dosage adjustments, special monitoring, or safety considerations outlined in the prescribing information. Therefore, healthcare professionals should exercise caution when prescribing this medication to individuals with reduced kidney function, as the absence of detailed guidance necessitates careful clinical judgment and monitoring of these patients.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

In the event of an overdosage, immediate medical intervention is crucial. If the product is swallowed, it is imperative to seek medical assistance or contact a Poison Control Center without delay.

Healthcare professionals should be aware that prompt action can significantly influence the outcome of an overdosage situation. Symptoms of overdosage may vary depending on the specific substance involved, and it is essential to monitor the patient closely for any adverse effects.

Management of overdosage should include supportive care and symptomatic treatment as necessary. The healthcare provider should assess the patient's condition and determine the appropriate course of action based on the severity of symptoms and the specific circumstances of the overdosage.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the use of the compound in these contexts.

Postmarketing Experience

No postmarketing experience details are available in the insert text.

Patient Counseling

Healthcare providers should advise patients to keep this medication out of reach of children to prevent accidental ingestion. Instruct patients that if the product is swallowed, they should seek medical help or contact a Poison Control Center immediately.

Patients should be informed to stop using the product and consult a doctor if they experience rectal bleeding or do not have a bowel movement after using the product, as these symptoms may indicate a serious condition.

Additionally, healthcare providers should encourage patients to ask a doctor before using any laxative if they have abdominal pain, nausea, or vomiting; if they have experienced a sudden change in bowel habits lasting more than two weeks; or if they have already used a laxative for more than one week. This guidance is essential to ensure the safe and effective use of the medication.

Storage and Handling

The product is supplied in a tightly sealed container to ensure integrity and stability. It is essential to store the container in a cool, dry place, away from excessive heat, to maintain optimal conditions. Proper handling includes ensuring that the container remains tightly closed when not in use to prevent contamination and degradation of the product.

Additional Clinical Information

No further data are available.

Drug Information (PDF)

This file contains official product information for Glycerin, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)