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Hydrocortisone 1% Anti-Itch Cream

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Active ingredient
Hydrocortisone 1 g/100 g
Other brand names
Drug class
Corticosteroid
Dosage form
Cream
Route
Topical
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2024
Label revision date
January 7, 2026
Drug Information (PDF)
Prescribing information, PDF file
Active ingredient
Hydrocortisone 1 g/100 g
Other brand names
Drug class
Corticosteroid
Dosage form
Cream
Route
Topical
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2024
Label revision date
January 7, 2026
Manufacturer
DLC Laboratories, Inc.
Registration number
M017
NDC root
24286-1578
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info
Packaging & NDC Codes

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

DeLaCruz® is a maximum strength hydrocortisone 1% anti-itch cream designed to provide temporary relief from itching caused by minor skin irritations, inflammation, and rashes. It can be effective for conditions such as eczema, insect bites, poison ivy, poison oak, poison sumac, and reactions to soaps, detergents, cosmetics, and jewelry. Additionally, it is suitable for external genital, feminine, and anal itching.

This cream is formulated with aloe vera and four moisturizers, making it gentle on the skin and free from dyes and fragrances. It is intended for use by individuals aged 2 years and older, and while it offers rapid relief for various skin issues, it is recommended to consult a doctor for any other uses.

Uses

This product is designed to provide temporary relief from itching caused by various minor skin irritations, inflammation, and rashes. You can use it for conditions like eczema, insect bites, and reactions to plants such as poison ivy, poison oak, and poison sumac. It can also help soothe irritation from soaps, detergents, cosmetics, jewelry, seborrheic dermatitis, and psoriasis.

Additionally, this product is effective for relieving itching in external genital areas, as well as feminine and anal itching. If you have other uses in mind, it's best to consult with your doctor for advice and supervision.

Dosage and Administration

If you are an adult or a child aged 2 years and older, you can apply this medication to the affected area up to 3 to 4 times a day. For best results, especially if you are treating external anal itching, it’s a good idea to first clean the area with mild soap and warm water, then rinse thoroughly. After that, gently dry the area by patting or blotting it with toilet tissue or a soft cloth before applying the product.

If your child is under 2 years old, do not use this medication without consulting a doctor. Additionally, if your child is under 12 years old and you are considering it for external anal itching, it’s important to speak with a doctor first. Always follow these guidelines to ensure safe and effective use of the medication.

What to Avoid

It's important to use this medication safely. You should not use it for treating diaper rash or for external feminine itching if you have a vaginal discharge—please consult your doctor in these cases. Additionally, avoid using any other hydrocortisone products without first talking to your doctor.

Make sure to keep the product away from your eyes and do not exceed the recommended dosage unless directed by a healthcare professional. Never insert this product into the rectum using fingers or any devices. If your condition worsens, persists for more than 7 days, or if you experience rectal bleeding, stop using the product and seek medical advice.

Side Effects

You should be aware that this product is for external use only. If your condition worsens, symptoms last more than 7 days, or if they improve and then return within a few days, it's important to stop using the product and consult a doctor. Additionally, if you experience rectal bleeding, seek medical advice immediately.

In case of accidental ingestion, please get medical help or contact a Poison Control Center right away. Always consult a doctor before starting any other hydrocortisone product.

Warnings and Precautions

This product is for external use only, so please avoid using it on diaper rashes or for external feminine itching if you have a vaginal discharge—consult your doctor in these cases. Be careful to keep the product away from your eyes, and do not use more than the recommended amount unless your doctor advises otherwise. It's important not to insert this product into the rectum using fingers or any devices.

If your condition worsens, symptoms last longer than 7 days, or if they clear up and then return within a few days, stop using the product and consult your doctor. Additionally, do not start any other hydrocortisone product without first talking to your doctor. If you experience rectal bleeding or if the product is swallowed, seek medical help immediately or contact a Poison Control Center.

Overdose

If you or someone else has swallowed too much of a medication, it’s important to seek medical help immediately. You can do this by contacting a Poison Control Center or going to the nearest emergency room.

Signs of an overdose can vary, but they may include unusual symptoms that are not typical for the medication. If you notice any concerning changes in behavior or health, don’t hesitate to get help. Remember, acting quickly can make a significant difference in the outcome.

Pregnancy Use

If you are pregnant or planning to become pregnant, it's important to know that the safety of hydrocortisone during pregnancy has not been established. You should consult your doctor before using this medication, as there may be potential risks to your fetus that are not clearly defined.

If your healthcare provider determines that hydrocortisone is necessary, they may recommend dosage adjustments to ensure your safety and that of your baby. Always use this medication only if it is clearly needed and if the benefits outweigh any potential risks.

Lactation Use

If you are breastfeeding, you can feel reassured that there are no specific warnings or recommendations regarding the use of this product while nursing. Additionally, there is no information available about whether this product is passed into breast milk or if it poses any risk to your infant. Always consult with your healthcare provider if you have any concerns or questions about medications while breastfeeding.

Pediatric Use

When using this medication for children, it's important to follow specific guidelines. For children aged 2 years and older, you can apply the medication to the affected area up to 3 to 4 times a day. However, if your child is under 2 years old, you should not use this medication without first consulting a doctor. Additionally, if your child is under 12 years old and is experiencing external anal itching, it's best to consult a doctor before use. Always prioritize your child's safety and seek professional advice when needed.

Geriatric Use

When it comes to using this medication in older adults, there is no specific information available about dosage adjustments, safety concerns, or special precautions. This means that if you or a loved one is an older adult, it’s important to consult with a healthcare provider for personalized advice. They can help determine the best approach based on individual health needs and any other medications being taken. Always prioritize open communication with your healthcare team to ensure safe and effective treatment.

Renal Impairment

If you have kidney problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or safety considerations for your condition. This means that there are no tailored guidelines for how this medication may affect you if your kidneys are not functioning properly.

Always consult your healthcare provider for personalized advice and to ensure that any medication you take is safe and appropriate for your kidney health. They can help monitor your condition and make any necessary adjustments to your treatment plan.

Hepatic Impairment

If you have liver problems, it's important to know that there are no specific guidelines or dosage adjustments mentioned for your condition in the available information. This means that the standard recommendations apply, and there are no special monitoring or precautions outlined for patients like you.

However, it's always best to discuss your individual health situation with your healthcare provider, as they can offer personalized advice and ensure that any medications you take are safe for your liver health.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you. Always share your complete list of medications and any health conditions you have to receive the best care possible.

Storage and Handling

To ensure the best performance of your product, store it at room temperature. This helps maintain its effectiveness and safety. When handling the product, be sure to follow any specific instructions provided to avoid contamination or damage. Always keep the product in a clean environment to ensure it remains safe for use. If you have any questions about disposal or additional safety measures, please refer to the guidelines provided with your product.

Additional Information

No further information is available.

FAQ

What is DeLaCruz®?

DeLaCruz® is a maximum strength hydrocortisone 1% anti-itch cream used for temporary relief of itching associated with minor skin irritations.

What conditions can DeLaCruz® help relieve?

It can relieve itching from eczema, insect bites, poison ivy, poison oak, poison sumac, soaps, detergents, cosmetics, jewelry, seborrheic dermatitis, and psoriasis.

Who can use DeLaCruz®?

DeLaCruz® is suitable for adults and children aged 2 years and older. Children under 2 years should consult a doctor before use.

How should I apply DeLaCruz®?

Apply to the affected area not more than 3 to 4 times daily. For external anal itching, cleanse the area with mild soap and warm water before application.

Are there any contraindications for using DeLaCruz®?

Do not use for diaper rash or external feminine itching if you have a vaginal discharge. Consult a doctor for other uses.

What should I do if my condition worsens?

Stop use and ask a doctor if your condition worsens, if symptoms persist for more than 7 days, or if rectal bleeding occurs.

Is DeLaCruz® safe to use during pregnancy?

The safety of hydrocortisone during pregnancy has not been established. Consult a doctor if pregnant or planning to become pregnant.

What should I do if I swallow DeLaCruz®?

If swallowed, get medical help or contact a Poison Control Center immediately.

Does DeLaCruz® contain any dyes or fragrances?

No, DeLaCruz® is dye-free and fragrance-free, making it suitable for sensitive skin.

Can I use DeLaCruz® on my face?

Consult a doctor before using DeLaCruz® on the face or for any other uses not specified.

Packaging Info

Below are the non-prescription pack sizes of Hydrocortisone 1% Anti-Itch Cream (hydrocortisone). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Hydrocortisone 1% Anti-Itch Cream.
Details

Drug Information (PDF)

This file contains official product information for Hydrocortisone 1% Anti-Itch Cream, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the specified drug.

Uses and Indications

This drug is indicated for the temporary relief of itching associated with minor skin irritation, inflammation, and rashes due to various conditions, including eczema, insect bites, poison ivy, poison oak, poison sumac, soaps, detergents, cosmetics, seborrheic dermatitis, and psoriasis. Additionally, it is indicated for external genital, feminine, and anal itching.

Other uses of this product should only be undertaken under the advice and supervision of a healthcare professional. There are no teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

For adults and children aged 2 years and older, the product should be applied to the affected area no more than 3 to 4 times daily. Prior to application, it is recommended that adults cleanse the affected area with mild soap and warm water, followed by thorough rinsing. The area should then be gently dried by patting or blotting with toilet tissue or a soft cloth before applying the product.

For children under 2 years of age, the product is not recommended, and consultation with a healthcare professional is advised. Additionally, for children under 12 years of age experiencing external anal itching, it is also necessary to consult a doctor before use.

Contraindications

The product is contraindicated for the treatment of diaper rash; consultation with a doctor is advised. It should not be used for external feminine itching in the presence of vaginal discharge without prior medical consultation.

Additionally, the initiation of any other hydrocortisone product is contraindicated unless a doctor has been consulted. Contact with the eyes must be avoided. The product should not be used in excess of the directed dosage unless specifically instructed by a healthcare professional. It is also contraindicated to administer the product rectally using fingers, mechanical devices, or applicators.

Patients should discontinue use and seek medical advice if the condition worsens, if symptoms persist for more than 7 days, or if symptoms resolve and then recur within a few days. Immediate cessation and consultation with a doctor are required if rectal bleeding occurs.

Warnings and Precautions

This product is intended for external use only. It is contraindicated for the treatment of diaper rash; healthcare professionals should advise patients to consult a doctor in such cases. Additionally, this product should not be used for external feminine itching if there is a vaginal discharge present; consultation with a healthcare provider is recommended.

Healthcare professionals should instruct patients to avoid contact with the eyes while using this product. It is imperative that patients adhere to the recommended dosage and not exceed the directed amount unless specifically advised by a doctor. The product should not be administered rectally using fingers, mechanical devices, or applicators.

Patients should be advised to discontinue use and seek medical advice if any of the following occur: the condition worsens, symptoms persist for more than 7 days, or if symptoms resolve and then recur within a few days. Furthermore, patients should not initiate the use of any other hydrocortisone product without prior consultation with a healthcare provider. In the event of rectal bleeding, immediate medical consultation is necessary.

In cases of accidental ingestion, patients should seek medical assistance or contact a Poison Control Center without delay.

Side Effects

Patients using this product should be aware that it is intended for external use only. In the event that the condition worsens, symptoms persist for more than 7 days, or symptoms clear up and then recur within a few days, patients are advised to stop use and consult a doctor. Additionally, if rectal bleeding occurs, it is imperative to discontinue use and seek medical attention.

It is important for patients to refrain from initiating the use of any other hydrocortisone product without prior consultation with a healthcare professional. In cases where the product is ingested, immediate medical assistance should be sought, or contact with a Poison Control Center is recommended.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there is no information available regarding interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Hydrocortisone 1% Anti-Itch Cream (hydrocortisone). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Hydrocortisone 1% Anti-Itch Cream.
Details

Pediatric Use

Pediatric patients aged 2 years and older may apply the medication to the affected area no more than 3 to 4 times daily. For children under 2 years of age, the use of this medication is not recommended, and a consultation with a doctor is advised. Additionally, for children under 12 years of age experiencing external anal itching, it is important to consult a doctor before use.

Geriatric Use

Elderly patients may not have specific information regarding the use of this medication, including dosage adjustments, safety concerns, or special precautions. Therefore, healthcare providers should exercise caution when prescribing this medication to geriatric patients. It is advisable to monitor these patients closely for any potential adverse effects or changes in efficacy, given the lack of targeted data for this population.

Pregnancy

The safety of hydrocortisone during pregnancy has not been established. Pregnant patients or those planning to become pregnant should consult a healthcare provider before use. Potential risks to the fetus are not clearly defined; therefore, caution is advised when considering treatment. Dosage adjustments may be necessary, and it is essential for healthcare providers to evaluate the need for hydrocortisone on a case-by-case basis. Use of this medication should only occur if clearly needed, and the benefits must outweigh the risks involved.

Lactation

There are no specific warnings or recommendations regarding the use of this product in nursing mothers. Additionally, there is no information available about the potential for excretion in breast milk or any associated risks to breastfed infants during lactation.

Renal Impairment

Patients with renal impairment have not been specifically studied in relation to dosage adjustments, special monitoring, or safety considerations for this medication. Therefore, healthcare professionals should exercise caution when prescribing this drug to individuals with reduced kidney function, as there is no available data to guide dosing or monitoring in this population.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there is no information available regarding dosage adjustments, special monitoring requirements, or precautions for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population.

Overdosage

In the event of an overdosage, immediate medical intervention is crucial. If the substance is ingested, it is imperative to seek medical assistance or contact a Poison Control Center without delay.

Healthcare professionals should be aware that prompt action can significantly influence the outcome of an overdosage situation. Symptoms of overdosage may vary depending on the specific substance involved; therefore, a thorough assessment and monitoring of the patient are essential.

Management procedures may include supportive care and symptomatic treatment, tailored to the individual patient's needs. Continuous evaluation and appropriate interventions should be implemented based on the clinical presentation and severity of symptoms.

In all cases of suspected overdosage, the involvement of poison control and emergency medical services is recommended to ensure optimal patient care and safety.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the use of the compound in question.

Postmarketing Experience

No postmarketing experience details are available in the insert.

Patient Counseling

Healthcare providers should advise patients to seek immediate medical assistance or contact a Poison Control Center if the product is swallowed. It is important to inform patients that this product is intended for the treatment of diaper rash and that they should consult a doctor for appropriate guidance.

Patients experiencing external feminine itching accompanied by vaginal discharge should also be instructed to consult a doctor before use. Healthcare providers should emphasize that if the condition worsens, or if symptoms persist for more than 7 days or resolve only to recur within a few days, patients should discontinue use and seek medical advice.

Providers should caution patients against the use of any other hydrocortisone products without prior consultation with a doctor. In the event of rectal bleeding, patients must stop using the product and consult a healthcare professional.

While using this product, patients should be advised to avoid contact with the eyes. It is crucial to instruct patients not to exceed the recommended dosage unless directed by a doctor. Additionally, patients should be informed that the product should not be inserted into the rectum using fingers or any mechanical devices or applicators.

Storage and Handling

The product is supplied in various package configurations, with specific NDC numbers assigned for identification. It is essential to store the product at room temperature to maintain its integrity and efficacy. No special handling requirements are noted; however, standard precautions should be observed to ensure optimal storage conditions.

Additional Clinical Information

No further data are available.

Drug Information (PDF)

This file contains official product information for Hydrocortisone 1% Anti-Itch Cream, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Hydrocortisone 1% Anti-Itch Cream, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

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Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.