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Instant Cooling Itch Relief

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Active ingredient
Hydrocortisone 10 mg/1 g
Other brand names
Drug class
Corticosteroid
Dosage form
Spray
Route
Topical
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2025
Label revision date
December 19, 2025
Drug Information (PDF)
Prescribing information, PDF file
Active ingredient
Hydrocortisone 10 mg/1 g
Other brand names
Drug class
Corticosteroid
Dosage form
Spray
Route
Topical
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2025
Label revision date
December 19, 2025
Manufacturer
CVS Pharmacy
Registration number
M017
NDC root
51316-388
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info
Packaging & NDC Codes

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

Hydrocortisone, 1% is an instant cooling itch relief spray designed to provide temporary relief from itching caused by minor skin irritations, inflammation, and rashes. This spray is effective for various conditions, including eczema, psoriasis, insect bites, poison ivy, oak, and sumac, as well as reactions to soaps, detergents, cosmetics, and jewelry.

With its touchless application, Hydrocortisone helps cover the itch, preventing it from spreading and allowing you to find comfort quickly.

Uses

You can use this medication to temporarily relieve itching caused by minor skin irritations, inflammation, and rashes. This includes conditions like eczema and psoriasis, as well as reactions to insect bites, poison ivy, oak, and sumac. It can also help with irritation from soaps, detergents, cosmetics, and even jewelry.

Rest assured, there are no known teratogenic effects (which means it doesn't cause birth defects) associated with this medication.

Dosage and Administration

Before using this medication, make sure to shake the bottle well. If you are an adult or a child aged 2 years and older, you can apply the medication to the affected area up to 3 to 4 times a day. If you need to apply it to your face, spray a small amount into the palm of your hand first, then gently apply it to your face.

For children under 2 years of age, it’s important to consult with a doctor before use. This ensures that the medication is safe and appropriate for their specific needs. Always follow these guidelines to ensure effective and safe use of the medication.

What to Avoid

It's important to use this product safely. You should avoid using it in or near your eyes, as well as for external genital, vaginal, or anal itching. Additionally, do not use it for diaper rash; if you have concerns about diaper rash, please consult a doctor for advice. Following these guidelines will help ensure your safety and the effectiveness of the product.

Side Effects

When using this product, it's important to be aware of some potential side effects and safety warnings. You should only use it externally and avoid contact with your eyes, as it can cause irritation. If you experience worsening symptoms or if your condition does not improve within 7 days, it's advisable to stop using the product and consult a doctor. Additionally, if you are pregnant or breastfeeding, please seek advice from a healthcare professional before use.

Remember to keep this product out of reach of children and pets. If ingested, seek medical help or contact a Poison Control Center immediately. Also, be cautious as the product is flammable; avoid using it near heat or flames, and do not store it at temperatures above 120 °F.

Warnings and Precautions

This product is for external use only, so please avoid using it near your eyes or for any genital, vaginal, or anal itching. It’s also not suitable for diaper rash; consult your doctor if you have questions. Remember, this product is flammable, so do not use it while smoking or near any heat sources or flames. Always use it as directed and keep it away from high temperatures (above 120 °F).

If you accidentally swallow the product, seek medical help or contact a Poison Control Center immediately. If your condition worsens or does not improve within 7 days, or if symptoms persist for more than 7 days or return shortly after clearing up, stop using the product and call your doctor.

Overdose

If you or someone else has swallowed a medication and you suspect an overdose, it’s important to act quickly. Seek medical help immediately or contact a Poison Control Center for guidance.

Signs of an overdose can vary, but they may include unusual symptoms that require prompt attention. Always err on the side of caution and reach out for help if you are unsure. Your safety is the top priority, so don’t hesitate to get the assistance you need.

Pregnancy Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using this medication. They can provide guidance on whether it’s safe for you and your baby. Always prioritize your health and the health of your child by seeking expert advice.

Lactation Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using any medication. This ensures that you understand any potential risks and can make informed decisions about your health and the health of your baby. Always prioritize open communication with your doctor regarding your breastfeeding journey.

Pediatric Use

If your child is under 2 years old, it's important to consult with a doctor before using this medication. For children aged 2 years and older, you can apply the medication to the affected area, but be sure not to exceed 3 to 4 applications per day. When applying it to the face, spray the product into your palm first, then gently apply it to your child's skin. Always follow these guidelines to ensure safe and effective use.

Geriatric Use

When it comes to using this medication in older adults, there is no specific information available about dosage adjustments, safety concerns, or special precautions. This means that if you or a loved one is an older adult considering this medication, it’s important to consult with a healthcare provider. They can help determine the best approach based on individual health needs and any other medications being taken.

Always ensure that your healthcare provider is aware of any existing health conditions or medications, as this can help in making informed decisions about treatment options. Your safety and well-being are the top priority, so don’t hesitate to ask questions or express any concerns you may have.

Renal Impairment

If you have kidney problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or safety considerations for your condition. This means that there are no tailored guidelines for how this medication may affect you if you have renal impairment (kidney issues).

Always consult your healthcare provider for personalized advice and to ensure that any medication you take is safe and appropriate for your health situation. They can help monitor your kidney function and make any necessary adjustments to your treatment plan.

Hepatic Impairment

If you have liver problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or precautions for your condition. This means that there are no tailored guidelines for how this medication may affect you if you have hepatic impairment (liver issues).

Before starting any new medication, including this one, you should discuss your liver health with your healthcare provider. They can help determine the best approach for your treatment and ensure your safety.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you.

Always feel free to ask questions and share your complete list of medications and any lab tests you may be undergoing. This way, you can receive the best possible care tailored to your needs.

Storage and Handling

When using this product, it's important to handle it with care to avoid any potential staining. Be cautious when spraying near fabrics and unprotected surfaces, as the product may leave marks. To ensure safety and effectiveness, always store the product in a cool, dry place, away from direct sunlight and extreme temperatures. Proper storage helps maintain its quality and performance.

If you have any leftover product, dispose of it according to local regulations to ensure safe and responsible handling.

Additional Information

No further information is available.

FAQ

What is Hydrocortisone, 1% used for?

Hydrocortisone, 1% is an instant cooling itch relief spray that temporarily relieves itching associated with minor skin irritation, inflammation, and rashes due to conditions like eczema, psoriasis, insect bites, and poison ivy.

How should I apply Hydrocortisone, 1%?

For adults and children 2 years and older, apply to the affected area up to 3 to 4 times daily. For the face, spray into your palm and gently apply.

Are there any warnings I should be aware of?

Yes, this product is for external use only, flammable, and should not be used in or near the eyes, for external genital itching, or for diaper rash without consulting a doctor.

What should I do if my condition worsens?

Stop using the product and ask a doctor if your condition worsens or does not improve within 7 days.

Can I use Hydrocortisone, 1% if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, you should ask a health professional before using this product.

What should I do if I accidentally swallow Hydrocortisone, 1%?

If swallowed, get medical help or contact a Poison Control Center right away.

Is there any specific information for children under 2 years of age?

Yes, you should ask a doctor before using Hydrocortisone, 1% on children under 2 years of age.

What are the storage instructions for Hydrocortisone, 1%?

Do not store Hydrocortisone, 1% at temperatures above 120 °F and do not puncture or incinerate the canister.

Packaging Info

Below are the non-prescription pack sizes of Instant Cooling Itch Relief (hydrocortisone). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Instant Cooling Itch Relief.
Details

Drug Information (PDF)

This file contains official product information for Instant Cooling Itch Relief, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the specified drug.

Uses and Indications

This drug is indicated for the temporary relief of itching associated with minor skin irritation, inflammation, and rashes due to various conditions, including eczema, psoriasis, insect bites, poison ivy, oak, and sumac, as well as reactions to soaps, detergents, cosmetics, and jewelry.

There are no teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

The formulation should be shaken well before use. For adults and children aged 2 years and older, the medication is to be applied to the affected area no more than 3 to 4 times daily. When applying to the face, it is recommended to spray the product into the palm of the hand and then gently apply it to the facial area.

For children under 2 years of age, it is advised to consult a physician prior to use.

Contraindications

Use is contraindicated in the following situations:

The product should not be applied in or near the eyes. Additionally, it is contraindicated for use in treating external genital, vaginal, or anal itching. The product is also not intended for diaper rash; consultation with a healthcare professional is advised in such cases.

Warnings and Precautions

For external use only. This product is flammable; therefore, it should not be used while smoking or in proximity to heat or flame. It is contraindicated for use in or near the eyes, and it should not be applied for external genital, vaginal, or anal itching. Additionally, it is not intended for use on diaper rash; consultation with a healthcare professional is advised in such cases.

General precautions must be observed. Care should be taken to avoid contact with the eyes; in the event of contact, rinse thoroughly with warm water. The product should be used strictly as directed. It is imperative not to puncture or incinerate the container, as it is under pressure. Storage should be maintained at temperatures not exceeding 120 °F to ensure product integrity.

In the event of accidental ingestion, immediate medical assistance should be sought, or contact with a Poison Control Center is recommended.

Patients should discontinue use and consult a healthcare provider if their condition worsens or fails to improve within 7 days. Additionally, if symptoms persist for more than 7 days or resolve only to recur within a few days, medical advice should be sought.

Side Effects

Patients should be aware of several important warnings and precautions associated with the use of this product. It is intended for external use only and is flammable; therefore, it should not be used while smoking or near heat or flame. The product should not be applied in or near the eyes, nor should it be used for external genital, vaginal, or anal itching, or for diaper rash without consulting a doctor.

While using this product, patients must take care to keep it out of the eyes and rinse with warm water if contact occurs. It is crucial to use the product only as directed, and patients should avoid puncturing or incinerating the container, as it is under pressure. Additionally, the product should not be stored at temperatures exceeding 120 °F.

Patients are advised to stop using the product and consult a doctor if their condition worsens or does not improve within 7 days, or if symptoms persist for more than 7 days or resolve and then recur within a few days. Pregnant or breastfeeding individuals should seek advice from a health professional before using this product.

It is essential to keep the product out of reach of children and pets. In the event of accidental ingestion, medical assistance should be sought immediately, or contact with a Poison Control Center should be made.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there is no information available regarding interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Instant Cooling Itch Relief (hydrocortisone). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Instant Cooling Itch Relief.
Details

Pediatric Use

Pediatric patients under 2 years of age should consult a healthcare professional before use. For children aged 2 years and older, the medication may be applied to the affected area up to 3 to 4 times daily. When applying to the face, it is recommended to spray the product into the palm of the hand and then gently apply it to the face.

Geriatric Use

There is no specific information available regarding the use of this medication in geriatric patients, including dosage adjustments, safety concerns, or special precautions. Healthcare providers should exercise caution when prescribing this medication to elderly patients, as individual responses may vary. It is advisable to monitor these patients closely for any adverse effects or changes in efficacy, given the lack of targeted data for this population.

Pregnancy

Pregnant patients and those who are breastfeeding should consult a healthcare professional prior to using this medication. The potential risks and benefits must be carefully weighed, as the effects on fetal outcomes and lactation are not fully established. It is essential for women of childbearing potential to seek medical advice to ensure safe use during pregnancy and lactation.

Lactation

Lactating mothers are advised to consult a health professional prior to using this medication. There is currently no available data on the excretion of this drug in human breast milk or its effects on breastfed infants. Therefore, caution is recommended when administering this medication to lactating individuals.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the drug insert regarding dosage adjustments, special monitoring, or safety considerations. Therefore, healthcare professionals should exercise caution when prescribing this medication to individuals with reduced kidney function, as the absence of detailed guidance necessitates careful clinical judgment. Regular monitoring of renal function may be advisable in these patients to ensure safety and efficacy.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the prescribing information.

Overdosage

In the event of an overdosage, immediate medical intervention is crucial. If the substance is ingested, it is imperative to seek medical assistance or contact a Poison Control Center without delay.

Healthcare professionals should be aware that prompt action can significantly influence the outcome of an overdosage situation. Symptoms of overdosage may vary depending on the specific substance involved; therefore, a thorough assessment and monitoring of the patient are essential.

Management procedures may include supportive care and symptomatic treatment, tailored to the individual patient's needs. Continuous evaluation and appropriate interventions should be implemented based on the clinical presentation and severity of symptoms.

In all cases of suspected overdosage, the involvement of poison control experts is recommended to guide the management and ensure the best possible care for the patient.

Nonclinical Toxicology

If pregnant or breast-feeding, it is advised to consult a health professional before use. No non-teratogenic effects have been provided in the insert. Additionally, there is no information available regarding nonclinical toxicology or animal pharmacology and toxicology in the insert.

Postmarketing Experience

No postmarketing experience details are available in the insert text.

Patient Counseling

Healthcare providers should advise patients to keep this product out of reach of children and pets to prevent accidental ingestion or misuse. Instruct patients that if the product is swallowed, they should seek medical help or contact a Poison Control Center immediately.

Patients should be informed not to use the product in or near the eyes, and to avoid application for external genital, vaginal, or anal itching. Additionally, it should not be used for diaper rash unless directed by a doctor.

Healthcare providers should counsel patients to discontinue use and consult a doctor if their condition worsens or does not improve within 7 days. They should also be advised to stop using the product and seek medical advice if symptoms persist for more than 7 days or if symptoms clear up and then recur within a few days.

When using the product, patients must be reminded to keep it out of their eyes and to rinse with warm water if contact occurs. It is essential to use the product only as directed.

Providers should inform patients not to puncture or incinerate the container, as it is under pressure. Furthermore, patients should be cautioned against storing the product at temperatures exceeding 120 °F to ensure safety and efficacy.

Storage and Handling

The product is supplied in configurations that may vary, and it is important to handle it with care due to its potential to cause staining. Caution is advised when spraying near fabrics and unprotected surfaces to prevent any unwanted marks.

For optimal storage, it is recommended to keep the product in a controlled environment, away from extreme temperatures. Specific temperature ranges and container requirements are not provided; however, general best practices for storage should be followed to maintain product integrity. Special handling needs include ensuring that the product is not exposed to conditions that may compromise its quality or effectiveness.

Additional Clinical Information

No further data are available.

Drug Information (PDF)

This file contains official product information for Instant Cooling Itch Relief, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Instant Cooling Itch Relief, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

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Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.