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Publix

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Active ingredient
Hydrocortisone 1 g/100 g
Other brand names
Drug class
Corticosteroid
Dosage form
Cream
Route
Topical
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 1989
Label revision date
July 8, 2025
Drug Information (PDF)
Prescribing information, PDF file
Active ingredient
Hydrocortisone 1 g/100 g
Other brand names
Drug class
Corticosteroid
Dosage form
Cream
Route
Topical
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 1989
Label revision date
July 8, 2025
Manufacturer
Publix Super Markets Inc
Registration number
M017
NDC root
41415-048
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info
Packaging & NDC Codes

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

Hydrocreamplus is a topical cream that contains 1% hydrocortisone, which is an antipruritic (anti-itch) agent designed to provide temporary relief from itching associated with various minor skin irritations and rashes. This includes conditions like eczema, insect bites, poison ivy, and reactions to soaps, detergents, cosmetics, jewelry, seborrheic dermatitis, psoriasis, and external genital and anal itching.

In addition to hydrocortisone, Hydrocreamplus is formulated with 12 moisturizers, including aloe, to help soothe and hydrate the skin while alleviating discomfort. It’s important to use this product as directed, and for any other uses, you should consult with a doctor.

Uses

This product is designed to provide temporary relief from itching caused by various minor skin irritations and rashes. You can use it for conditions such as eczema, insect bites, and reactions to plants like poison ivy, poison oak, or poison sumac. It can also help soothe itching from soaps, detergents, cosmetics, jewelry, seborrheic dermatitis, psoriasis, and even external genital and anal itching.

For any other uses, it's important to consult with your doctor to ensure it's appropriate for your situation.

Dosage and Administration

When using this medication, you should apply it to the affected area no more than 3 to 4 times a day if you are an adult or a child aged 2 years and older. For children under 2 years old, it’s important not to use this product without first consulting a doctor.

Before applying the medication, adults are advised to clean the affected area with mild soap and warm water, making sure to rinse it thoroughly. After cleaning, gently dry the area by patting or blotting it with toilet tissue or a soft cloth. If you are caring for a child under 12 years of age, please consult a doctor before use to ensure it is safe for them.

What to Avoid

It's important to use this product safely and effectively. You should not use it in your eyes or insert it into the rectum using your fingers or any mechanical device or applicator. Following these guidelines helps prevent potential harm and ensures the product works as intended. If you have any questions about how to use this product correctly, please consult your healthcare provider.

Side Effects

This product is intended for external use only, so be sure to avoid contact with your eyes and do not insert it into the rectum using fingers or any devices. Before using it, consult a doctor if you have any vaginal discharge, rectal bleeding, or diaper rash.

While using this product, it's important not to exceed the recommended dosage. If your condition worsens, persists for more than seven days, or clears up only to return within a few days, stop using it and consult a doctor. Keep this product out of reach of children, and if swallowed, seek medical help or contact a Poison Control Center immediately.

Warnings and Precautions

This product is for external use only, so please avoid contact with your eyes and do not insert it into the rectum using fingers or any devices. Before using this product, it's important to consult your doctor if you have any vaginal discharge, rectal bleeding, or diaper rash.

While using this product, be sure to follow the recommended dosage and check with your doctor if you feel the need to exceed it. You should stop using the product and contact your doctor if your condition worsens, does not improve after 7 days, or if it clears up and then returns within a few days. Avoid using any other hydrocortisone products without consulting your doctor first.

Keep this product out of reach of children. If swallowed, seek medical help or contact a Poison Control Center immediately.

Overdose

If you or someone else has swallowed too much of this medication, it’s important to seek medical help immediately or contact a Poison Control Center. Signs of an overdose can vary, but they may include unusual symptoms that are not typical when taking the medication as prescribed.

Always err on the side of caution. If you suspect an overdose, don’t wait for symptoms to appear—reach out for help right away. Your safety is the top priority, and medical professionals are equipped to provide the necessary assistance.

Pregnancy Use

If you are pregnant or planning to become pregnant, it's important to know that there are no specific guidelines or safety concerns mentioned about using hydrocortisone cream during pregnancy. This means that the drug insert does not provide information on whether you need to adjust the dosage or take any special precautions while using this cream.

As always, it's best to consult with your healthcare provider before using any medication during pregnancy to ensure it is safe for you and your baby.

Lactation Use

If you are breastfeeding, you can feel reassured that there are no specific warnings or recommendations regarding the use of this product while nursing. Additionally, there is no information available about whether this product is excreted in breast milk or any potential risks it may pose to your infant. Always consult with your healthcare provider if you have any concerns or questions about medications while breastfeeding.

Pediatric Use

When using this medication for children, it's important to follow specific guidelines. For children aged 2 years and older, you can apply it to the affected area up to 3 to 4 times a day. However, if your child is under 2 years old, you should not use this medication without first consulting a doctor. Additionally, if your child is under 12 years of age, it's best to check with a doctor before use to ensure safety and proper dosage. Always prioritize your child's health by seeking professional advice when needed.

Geriatric Use

When considering the use of Publix Hydro Plus (hydrocortisone cream) for older adults, it's important to note that the drug insert does not provide specific information about its use in this age group. This means that there may not be tailored guidelines or dosage recommendations specifically for elderly patients.

As always, if you or a caregiver are considering this treatment, it's wise to consult with a healthcare professional. They can help determine if this cream is appropriate for your needs and discuss any potential risks or benefits based on your overall health and any other medications you may be taking.

Renal Impairment

If you have kidney problems, it's important to know that the information provided does not include specific guidelines for dosage adjustments, special monitoring, or safety considerations related to renal impairment (kidney issues). This means that there are no tailored recommendations for how your treatment may need to change based on your kidney function.

Always consult your healthcare provider for personalized advice and to ensure that your treatment plan is safe and effective for your specific situation. They can help monitor your kidney health and make any necessary adjustments to your medications.

Hepatic Impairment

If you have liver problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or precautions for your condition. This means that there are no tailored guidelines for how this medication should be used if you have hepatic impairment (liver issues).

Always consult your healthcare provider for personalized advice and to ensure that any medication you take is safe and appropriate for your liver health. They can help determine the best course of action based on your individual situation.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications you are taking, even if there are no known drug interactions or laboratory test interactions associated with them. This ensures that your treatment plan is safe and effective for your individual health needs.

Always keep your healthcare team informed about all the medications and supplements you use, as well as any lab tests you may undergo. This way, they can provide the best care tailored to you.

Storage and Handling

To ensure the best quality and safety of your product, store it at room temperature. It's important to check the carton or tube crimp for the lot number and expiration date, as this information helps you confirm the product's validity and safety for use.

Always handle the product with care, and make sure to follow any additional instructions provided to maintain its integrity. Proper storage and attention to these details will help you use the product effectively and safely.

Additional Information

You should apply this product to the affected area no more than 3 to 4 times daily if you are an adult or a child aged 2 years and older. If you are dealing with external anal itching, it's recommended to first cleanse the area with mild soap and warm water, rinse thoroughly, and then gently dry it by patting or blotting with toilet tissue or a soft cloth before applying the product.

FAQ

What is hydrocreamplus?

Hydrocreamplus is a topical cream containing 1% hydrocortisone, which is an antipruritic (anti-itch) agent, along with 12 moisturizers and aloe for itch and rash relief.

What conditions can hydrocreamplus help relieve?

It provides temporary relief from itching associated with minor skin irritations and rashes due to eczema, insect bites, poison ivy, soaps, detergents, cosmetics, and more.

How should I use hydrocreamplus?

Apply hydrocreamplus to the affected area not more than 3 to 4 times daily for adults and children 2 years and older. For children under 2, consult a doctor.

Are there any warnings for using hydrocreamplus?

Yes, it is for external use only. Do not use in the eyes or insert it into the rectum. Consult a doctor if you have vaginal discharge, rectal bleeding, or diaper rash.

What should I do if my condition worsens while using hydrocreamplus?

Stop use and consult a doctor if your condition worsens, persists for more than 7 days, or clears up and occurs again within a few days.

Is hydrocreamplus safe to use during pregnancy or while nursing?

There are no specific warnings or recommendations regarding the use of hydrocreamplus during pregnancy or nursing mothers.

How should I store hydrocreamplus?

Store hydrocreamplus at room temperature and check the carton or tube crimp for the lot number and expiration date.

What should I do if I accidentally swallow hydrocreamplus?

Keep hydrocreamplus out of reach of children. If swallowed, get medical help or contact a Poison Control Center immediately.

Packaging Info

Below are the non-prescription pack sizes of Publix (hydrocortisone). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Publix.
Details

Drug Information (PDF)

This file contains official product information for Publix, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

Publix Hydrocreamplus contains 1% hydrocortisone, serving as an antipruritic agent to alleviate itching. This formulation is designed to provide relief from itch and rash, incorporating 12 moisturizers, including aloe, to enhance skin hydration. The product is presented in a cream dosage form, with a net weight of 1 oz (28.4 g).

Uses and Indications

This drug is indicated for the temporary relief of itching associated with minor skin irritations and rashes due to various conditions, including eczema, insect bites, poison ivy, poison oak, poison sumac, soaps, detergents, cosmetics, seborrheic dermatitis, psoriasis, and external genital and anal itching.

Other uses of this product should only be undertaken under the advice and supervision of a healthcare professional. There are no teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

For adults and children aged 2 years and older, the product should be applied to the affected area no more than 3 to 4 times daily. Prior to application, it is recommended that the affected area be cleansed with mild soap and warm water, followed by thorough rinsing. The area should then be gently dried by patting or blotting with toilet tissue or a soft cloth before applying the product.

For children under 2 years of age, the product should not be used without consulting a doctor. Additionally, for children under 12 years of age, it is advised to consult a doctor prior to use.

Contraindications

Use of this product is contraindicated in the eyes due to the potential for irritation and damage to ocular tissues. Additionally, administration via the rectum using fingers, mechanical devices, or applicators is contraindicated to prevent injury or adverse reactions.

Warnings and Precautions

For external use only, this product is contraindicated for application in the eyes and should not be administered rectally, either manually or with any mechanical device or applicator.

Healthcare professionals should advise patients to consult a physician prior to use if they present with any of the following conditions: vaginal discharge, rectal bleeding, or diaper rash. It is imperative that patients adhere to the recommended dosage; exceeding this dosage should only occur under medical supervision.

Patients must be instructed to discontinue use and seek medical advice if any of the following occur: the condition worsens, persists beyond 7 days, or resolves only to recur within a few days. It is essential that patients do not initiate the use of any other hydrocortisone product without prior consultation with a healthcare provider.

To ensure safety, this product should be kept out of reach of children. In the event of accidental ingestion, immediate medical assistance should be sought, or contact with a Poison Control Center is advised.

Side Effects

Patients should be aware that this product is for external use only and should not be applied in or around the eyes, nor should it be administered rectally using fingers or any mechanical device or applicator.

Before using this product, patients are advised to consult a doctor if they have a vaginal discharge, rectal bleeding, or diaper rash. During the use of this product, it is important to adhere to the recommended dosage; exceeding this dosage should be discussed with a healthcare professional.

Patients should discontinue use and seek medical advice if their condition worsens, persists for more than 7 days, or if the condition clears up and recurs within a few days. It is also recommended that patients refrain from using any other hydrocortisone products without prior consultation with a doctor.

This product should be kept out of reach of children. In the event of accidental ingestion, patients should seek medical assistance or contact a Poison Control Center immediately.

Drug Interactions

No specific drug interactions have been identified for this medication. Additionally, there are no reported interactions with laboratory tests. Therefore, no dosage adjustments or monitoring recommendations are necessary based on drug or laboratory test interactions.

Packaging & NDC

Below are the non-prescription pack sizes of Publix (hydrocortisone). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Publix.
Details

Pediatric Use

Pediatric patients aged 2 years and older may apply the medication to the affected area no more than 3 to 4 times daily. For children under 2 years of age, the medication is not recommended, and a consultation with a doctor is advised. Additionally, for children under 12 years of age, it is also recommended to consult a doctor prior to use.

Geriatric Use

There is no specific information regarding the use of Publix Hydro Plus (hydrocortisone cream) in geriatric patients. Therefore, healthcare providers should exercise caution when prescribing this medication to elderly patients.

Given the lack of data, it is advisable to monitor geriatric patients closely for any potential adverse effects or changes in response to treatment. Additionally, consideration should be given to the overall health status and comorbidities of elderly patients, which may necessitate dose adjustments or increased vigilance during therapy.

Pregnancy

There are no specific statements regarding the use of hydrocortisone cream during pregnancy, including safety concerns, dosage modifications, or special precautions. As such, healthcare professionals should consider the lack of data when prescribing this medication to pregnant patients. It is advisable to weigh the potential benefits against any unknown risks to fetal outcomes. Women of childbearing potential should be counseled on the importance of discussing any medications with their healthcare provider prior to use during pregnancy.

Lactation

There are no specific warnings or recommendations regarding the use of this product in nursing mothers. Additionally, there is no information available about the potential for excretion in breast milk or any associated risks to breastfed infants.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the prescribing information regarding dosage adjustments, special monitoring, or safety considerations. Therefore, healthcare professionals should exercise caution when prescribing this medication to patients with reduced kidney function, as the absence of detailed guidance necessitates careful clinical judgment. Regular monitoring of renal function may be advisable in these patients to ensure safety and efficacy.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to this drug. Consequently, there are no dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the prescribing information.

Overdosage

In the event of an overdosage, immediate medical intervention is crucial. If the substance is ingested, it is imperative to seek medical assistance or contact a Poison Control Center without delay.

Healthcare professionals should be aware that prompt action can significantly influence the outcome of an overdosage situation. Symptoms of overdosage may vary depending on the specific substance involved; therefore, a thorough assessment and monitoring of the patient are essential.

Management procedures may include supportive care and symptomatic treatment, tailored to the individual patient's needs. Continuous evaluation and appropriate interventions should be implemented based on the clinical presentation and severity of symptoms.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the compound in these areas.

Postmarketing Experience

No postmarketing experience details are available in the insert text.

Patient Counseling

Healthcare providers should advise patients to keep this product out of reach of children. In the event of accidental ingestion, patients should seek medical assistance or contact a Poison Control Center immediately.

Patients should be informed that this product is not intended for use in the eyes and should not be administered rectally using fingers, mechanical devices, or applicators.

Healthcare providers should instruct patients to discontinue use and consult a doctor if their condition worsens, persists for more than 7 days, or resolves only to recur within a few days. Patients should be cautioned against starting any other hydrocortisone product without prior consultation with a healthcare professional.

When using this product, patients should be advised to consult a doctor before exceeding the recommended dosage. Additionally, patients should be encouraged to seek medical advice before use if they experience vaginal discharge, rectal bleeding, or have a diaper rash.

Storage and Handling

The product is supplied in various packaging configurations, with specific NDC numbers available upon request. It should be stored at room temperature to maintain its efficacy. For traceability, healthcare professionals are advised to refer to the carton or tube crimp for the lot number and expiration date. Proper handling is essential to ensure the integrity of the product throughout its shelf life.

Additional Clinical Information

For patients aged 2 years and older, the product should be applied to the affected area no more than 3 to 4 times daily. In cases of external anal itching, it is recommended that adults cleanse the affected area with mild soap and warm water, rinse thoroughly, and gently dry by patting or blotting with toilet tissue or a soft cloth prior to application.

No additional information is available regarding laboratory tests, abuse potential, patient counseling, or postmarketing experience.

Drug Information (PDF)

This file contains official product information for Publix, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Publix, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.