ADD CONDITION

items per page

Lip Clear Lysine Plus

Last content change checked dailysee data sync status

Active ingredient
Menthol, Unspecified Form 1 mg/1 g
Other brand names
Dosage form
Ointment
Route
Topical
Prescription status
OTC (over the counter)
Marketed in the U.S.
Since 1984
Label revision date
October 20, 2025
Active ingredient
Menthol, Unspecified Form 1 mg/1 g
Other brand names
Dosage form
Ointment
Route
Topical
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Marketed in the U.S.
Since 1984
Label revision date
October 20, 2025
Manufacturer
Quantum, Inc.
Registration number
M017
NDC root
70084-320

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

LIP CLEAR® Lysine+® is a treatment specifically designed for cold sores, also known as fever blisters. It works by relieving symptoms such as tingling, itching, burning, and pain associated with these outbreaks. This product not only provides fast pain relief but also helps to cut healing time in half, so you can feel better sooner.

Formulated with 14 nutrients, including lysine (an amino acid that may help prevent outbreaks), propolis (a natural substance made by bees), olive oil, and vitamin E, LIP CLEAR® Lysine+® aims to soothe and moisturize the affected area, making your experience more comfortable.

Uses

If you're dealing with cold sores or fever blisters, this treatment can help you feel better quickly. It relieves uncomfortable symptoms like tingling, itching, burning, blistering, and pain. You can expect fast pain relief, which can make a big difference in your day-to-day comfort.

In addition to easing your symptoms, this treatment also cuts your healing time in half. It soothes and moisturizes the affected area, helping to stop the burning and itching sensations that can be so bothersome. Overall, it provides comprehensive relief, allowing you to get back to your routine more comfortably.

Dosage and Administration

When using this medication for yourself or for children aged 2 and older, you should apply it generously as needed. For the best results, it's recommended that you reapply the medication every two hours.

Before you apply the medication, make sure to wash your hands thoroughly. This helps ensure that the application is clean and effective. Don’t forget to wash your hands again after applying the medication to keep everything hygienic.

What to Avoid

It's important to be cautious when using this medication. You should avoid getting it into your eyes, as this can cause irritation or other issues. There are no specific contraindications, controlled substance classifications, or concerns about abuse, misuse, or dependence associated with this medication. Always follow the instructions provided to ensure safe and effective use.

Side Effects

When using this product, it's important to remember that it is for external use only and should not come into contact with your eyes. If your condition worsens, or if symptoms persist for more than 7 days or return after clearing up, you should stop using the product and consult a doctor.

Additionally, keep this product out of reach of children. If it is swallowed, seek medical help or contact a Poison Control Center immediately.

Warnings and Precautions

This product is intended for external use only, so be sure to avoid contact with your eyes. It's important to keep this product out of reach of children. If a child accidentally swallows it, seek medical help or contact a Poison Control Center immediately.

You should stop using the product and consult your doctor if your condition worsens, if your symptoms last longer than 7 days, or if your symptoms improve and then return. Taking these precautions can help ensure your safety and well-being while using this product.

Overdose

If you or someone else has swallowed too much of a medication, it’s important to seek medical help immediately. You can do this by contacting a Poison Control Center or going to the nearest emergency room.

Signs of an overdose can vary, but they may include unusual symptoms that are not typical for the medication. If you notice any concerning changes in behavior or health, don’t hesitate to get help. Remember, acting quickly can make a significant difference in the outcome.

Pregnancy Use

The product has not been specifically studied for use during pregnancy, which means there is limited information on its safety for you and your developing baby. However, the insert does not include any explicit warnings or contraindications for pregnant individuals, suggesting that it may be considered safe.

There are also no dosage modifications or special precautions outlined for pregnant individuals. As always, it's important to discuss any medications with your healthcare provider to ensure they are appropriate for your situation.

Lactation Use

If you are breastfeeding, you can feel reassured that there are no specific warnings or recommendations regarding the use of this product while nursing. Additionally, there are no statements indicating that the product is excreted in breast milk or that it poses any risk to your infant during lactation. This means you can use the product without concern for its effects on your milk production or your baby's health.

Pediatric Use

You can use this product for both adults and children aged 2 years and older. It's important to apply it generously and as often as needed. For optimal effectiveness, aim to reapply it every two hours. This will help ensure that your child receives the best possible protection.

Geriatric Use

While there is no specific information available about the use of this medication in older adults, it’s important to approach any new treatment with caution. If you or a loved one is an older adult, it’s always a good idea to discuss any medications with a healthcare provider. They can help ensure that the treatment is safe and appropriate, considering any unique health needs or conditions.

Since there are no dosage adjustments or special precautions mentioned for elderly patients, your healthcare provider will be the best resource for personalized advice. They can monitor for any potential side effects and make recommendations based on individual health status.

Renal Impairment

If you have kidney problems, it's important to know that the information provided does not include specific guidelines for dosage adjustments, special monitoring, or safety considerations related to renal impairment (kidney issues). This means that there are no tailored recommendations for how your treatment may need to change based on your kidney function.

Always consult your healthcare provider for personalized advice and to ensure that your treatment plan is safe and effective for your specific situation. They can help monitor your kidney health and make any necessary adjustments to your medications.

Hepatic Impairment

If you have liver problems, it's important to know that the information provided does not include specific guidelines for dosage adjustments, special monitoring, or precautions related to your condition. This means that there are no tailored recommendations for how the medication may need to be adjusted or monitored based on your liver function.

Always consult your healthcare provider for personalized advice and to ensure that any treatment plan is safe and effective for you, especially if you have a history of liver issues. Your doctor can help determine the best approach based on your individual health needs.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that your overall treatment plan is safe and effective.

Always discuss any other medications, supplements, or health conditions you have, as this information is crucial for your safety and well-being. Your provider can guide you on how to manage your health effectively.

Storage and Handling

To ensure the best performance of your product, store it at room temperature and keep it away from excessive heat. This helps maintain its effectiveness and safety. After each use, make sure to close the cover tightly to protect the contents and prevent contamination.

By following these simple storage and handling guidelines, you can help ensure that your product remains safe and effective for your needs.

Additional Information

You can use this medication topically, which means you apply it directly to your skin. It is suitable for both adults and children aged 2 and older. For the best results, apply it liberally as needed, ideally every two hours. Remember to wash your hands before and after applying the medication to ensure cleanliness and effectiveness.

FAQ

What is LIP CLEAR® Lysine+® used for?

LIP CLEAR® Lysine+® is a cold sore treatment that relieves tingling, itching, burning, blistering, and pain associated with cold sores or fever blisters.

How does LIP CLEAR® Lysine+® work?

It cuts healing time in half, provides fast pain relief, stops burning and itching, and soothes and moisturizes the affected area.

What ingredients are in LIP CLEAR® Lysine+®?

It contains 14 nutrients, including Lysine, Propolis, Olive Oil, and Vitamin E.

How should I use LIP CLEAR® Lysine+®?

For adults and children 2 and older, apply liberally as needed, ideally every two hours. Be sure to wash your hands before and after applying.

Are there any warnings for using LIP CLEAR® Lysine+®?

Yes, it is for external use only, and you should avoid getting it into your eyes.

What should I do if my condition worsens while using this product?

Stop use and ask a doctor if your condition worsens or if symptoms last more than 7 days or clear up and occur again.

Is LIP CLEAR® Lysine+® safe to use during pregnancy?

The product has not been specifically evaluated for use during pregnancy, and there are no explicit warnings or contraindications mentioned.

Can nursing mothers use LIP CLEAR® Lysine+®?

There are no specific warnings or recommendations regarding the use of this product in nursing mothers.

What should I do if LIP CLEAR® Lysine+® is swallowed?

Keep it out of reach of children, and if swallowed, get medical help or contact a Poison Control Center right away.

How should I store LIP CLEAR® Lysine+®?

Store at room temperature and avoid excessive heat. Close the cover tightly after each use.

Packaging Info

Below are the non-prescription pack sizes of Lip Clear Lysine Plus (menthol, unspecified form). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Lip Clear Lysine Plus.
Details

Drug Information (PDF)

This file contains official product information for Lip Clear Lysine Plus, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the drug.

Uses and Indications

This drug is indicated for the relief of tingling, itching, burning, blistering, and pain associated with cold sores and fever blisters. It is designed to provide fast pain relief while cutting healing time in half. Additionally, this formulation soothes and moisturizes the affected area, effectively stopping burning and itching sensations.

There are no teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

For adults and children aged 2 years and older, the product should be applied liberally as needed. For optimal efficacy, it is recommended to apply the product every two hours. Prior to application, healthcare professionals should instruct patients to wash their hands thoroughly, and it is equally important to wash hands again after application to maintain hygiene.

Contraindications

Use of this product is contraindicated in individuals with a known hypersensitivity to any of its components. Additionally, the product should not be applied to the eyes, as this may result in irritation or injury.

Warnings and Precautions

This product is intended for external use only. It is imperative to avoid contact with the eyes during application. In the event of accidental contact, immediate rinsing with water is recommended.

Healthcare professionals should advise patients to discontinue use and seek medical advice if any of the following occur: the condition worsens, symptoms persist for more than 7 days, or if symptoms resolve and then recur.

Additionally, it is crucial to keep this product out of reach of children. In cases of ingestion, immediate medical assistance should be sought, or contact with a Poison Control Center is advised.

Side Effects

Patients using this product should be aware that it is intended for external use only. Care should be taken to avoid contact with the eyes, as this may lead to adverse reactions.

In the event that the condition being treated worsens, or if symptoms persist for more than 7 days or resolve and then recur, patients are advised to discontinue use and consult a healthcare professional.

Additionally, this product should be kept out of reach of children. If ingested, immediate medical assistance should be sought, or contact with a Poison Control Center is recommended.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there are no known interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Lip Clear Lysine Plus (menthol, unspecified form). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Lip Clear Lysine Plus.
Details

Pediatric Use

Pediatric patients aged 2 years and older may use the product. It is recommended to apply liberally as needed, with optimal results achieved by reapplication every two hours.

Geriatric Use

Elderly patients may not have specific information regarding the use of this medication, including dosage adjustments, safety concerns, or special precautions. Therefore, healthcare providers should exercise caution when prescribing this medication to geriatric patients. It is advisable to monitor these patients closely for any adverse effects or changes in therapeutic response, given the lack of targeted data for this population.

Pregnancy

The product has not been specifically evaluated for use during pregnancy. There are no explicit warnings or contraindications regarding its use in pregnant patients. Additionally, the prescribing information does not provide any dosage modifications for individuals who are pregnant. Furthermore, no special precautions concerning the use of this product during pregnancy are mentioned. Healthcare professionals should consider the lack of specific data when prescribing this product to pregnant patients and weigh the potential benefits against any unknown risks.

Lactation

There are no specific warnings or recommendations regarding the use of this product in nursing mothers. Additionally, there are no statements concerning the potential for excretion in breast milk or any associated risks to breastfed infants during the use of this product in lactation.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the available prescribing information. There are no dosage adjustments, special monitoring requirements, or safety considerations outlined for individuals with reduced kidney function. Healthcare professionals should exercise caution and consider the lack of data when prescribing to this patient population.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

In the event of an overdosage, immediate medical assistance is crucial. If the substance is ingested, healthcare professionals should advise patients or caregivers to seek medical help or contact a Poison Control Center without delay.

Prompt intervention is essential to mitigate potential adverse effects associated with overdosage. Symptoms may vary depending on the specific substance involved, and healthcare providers should be prepared to assess and manage these symptoms accordingly.

Management procedures may include supportive care and symptomatic treatment, tailored to the individual patient's needs. Continuous monitoring and evaluation are recommended to ensure patient safety and effective resolution of any complications arising from the overdosage.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the compound in these areas.

Postmarketing Experience

No postmarketing experience details are available in the insert.

Patient Counseling

Healthcare providers should advise patients to keep this product out of reach of children to prevent accidental ingestion. In the event that the product is swallowed, patients should seek medical help or contact a Poison Control Center immediately.

Patients should be informed to discontinue use and consult a doctor if their condition worsens or if symptoms persist for more than 7 days. Additionally, if symptoms resolve and then recur, patients should also stop using the product and seek medical advice.

It is important to instruct patients to avoid contact with the eyes while using this product, as this may lead to irritation or other adverse effects.

Storage and Handling

The product is supplied in configurations that ensure optimal usability. It should be stored at room temperature, with precautions taken to avoid exposure to excessive heat. To maintain the integrity of the product, it is essential to close the cover tightly after each use.

Additional Clinical Information

The product is administered topically for both adults and children aged 2 years and older. It is recommended to apply liberally as needed, with optimal results achieved by reapplication every two hours. Clinicians should advise patients to wash their hands before and after application to ensure proper hygiene.

No additional information is available regarding laboratory tests, abuse potential, patient counseling, or postmarketing experience.

Drug Information (PDF)

This file contains official product information for Lip Clear Lysine Plus, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Lip Clear Lysine Plus, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.