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Listerine Total Care Alcohol Free Anticavity Fluoride Mouthwash Fresh Mint

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Active ingredient
Sodium Fluoride 0.1 mg/1 mL
Other brand names
Dosage form
Mouthwash
Route
Oral
Prescription status
OTC (over the counter)
Marketed in the U.S.
Since 2025
Label revision date
May 5, 2025
Active ingredient
Sodium Fluoride 0.1 mg/1 mL
Other brand names
Dosage form
Mouthwash
Route
Oral
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Marketed in the U.S.
Since 2025
Label revision date
May 5, 2025
Manufacturer
Kenvue Brands LLC
Registration number
M021
NDC root
69968-0924

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Drug Overview

LISTERINE® TOTAL CARE is an anticavity fluoride mouthwash designed to help you maintain good oral health. It contains sodium fluoride and acidulated phosphate, which work together to prevent dental cavities, restore enamel, and strengthen your teeth. This mouthwash also kills 99.9% of germs, providing 24-hour cavity protection while freshening your breath and cleaning your whole mouth.

With its alcohol-free formula and mild taste, LISTERINE® TOTAL CARE offers six benefits in one product, making it a convenient choice for your daily oral hygiene routine. For optimal results, it is recommended to use the mouthwash twice daily.

Uses

You can use this product to help prevent dental cavities, which are holes in your teeth caused by decay. By incorporating it into your oral care routine, you can support your dental health and reduce the risk of developing these issues.

It's important to note that there are no reported teratogenic effects (harmful effects on the development of a fetus) or nonteratogenic effects (harmful effects that do not involve fetal development) associated with this product, making it a safe option for most users.

Dosage and Administration

To use this mouth rinse effectively, you should follow these steps. If you are an adult or a child aged 6 years and older, use the rinse twice a day after brushing your teeth with toothpaste. Measure out 10 mL (which is about 2 teaspoonfuls) of the rinse and swish it vigorously between your teeth for 1 minute before spitting it out. Remember, do not swallow the rinse.

After using the mouth rinse, it's important not to eat or drink anything for 30 minutes to allow the rinse to work effectively. If you are supervising a child under 12, make sure to teach them proper rinsing habits to help prevent swallowing the rinse. For children under 6 years of age, it's best to consult a dentist or doctor before use.

What to Avoid

It's important to be cautious when using this product. If you accidentally swallow more than what is intended for rinsing, you should seek medical help immediately or contact a Poison Control Center. This is a critical step to ensure your safety.

Currently, there are no specific contraindications, risks of abuse or misuse, or concerns about dependence associated with this product. However, always use it as directed to avoid any potential issues.

Side Effects

It's important to keep this product out of reach of children. If a child accidentally swallows more than what is used for rinsing, seek medical help or contact a Poison Control Center immediately. This precaution helps ensure safety and prevent any potential harm.

Warnings and Precautions

It's important to keep this product out of reach of children. If a child accidentally swallows more than what is used for rinsing, seek medical help immediately or contact a Poison Control Center.

Always use this product as directed. If you experience any unusual symptoms or reactions, stop using it and call your doctor for further advice. Your safety is a priority, so don’t hesitate to reach out for help if needed.

Overdose

If you accidentally swallow more of this product than intended for rinsing, it’s important to seek medical help immediately or contact a Poison Control Center. Overdosing can lead to serious health issues, so don’t hesitate to reach out for assistance.

Signs of an overdose may not always be obvious, but if you experience any unusual symptoms after swallowing too much, it’s crucial to get help right away. Always prioritize your safety and well-being by being aware of the proper usage and seeking help if something goes wrong.

Pregnancy Use

There is no specific information available about the use of Listerine Total Care Alcohol Free Anticavity Fluoride Mouthwash during pregnancy. This means that the drug insert does not provide details on safety concerns, dosage adjustments, or any special precautions you should take if you are pregnant or planning to become pregnant.

If you have any questions or concerns about using this mouthwash while pregnant, it’s best to consult with your healthcare provider for personalized advice.

Lactation Use

If you are breastfeeding or planning to breastfeed, it's important to be aware that there is no specific information available regarding the use of this medication during nursing. This means that the effects on breast milk and your nursing infant are not clearly defined.

As always, it's best to consult with your healthcare provider about any medications you are considering while breastfeeding. They can help you weigh the potential risks and benefits to ensure the safety of both you and your baby.

Pediatric Use

It's important to keep this product out of reach of children. If a child accidentally swallows more than the amount used for rinsing, seek medical help or contact a Poison Control Center immediately. For children aged 6 years and older, you can use this product twice a day after brushing their teeth with toothpaste.

For children under 12, make sure to teach them proper rinsing habits to help prevent swallowing. Always supervise younger children until they can use the product safely on their own. If your child is under 6 years old, it's best to consult with a dentist or doctor before use.

Geriatric Use

When it comes to using this medication in older adults, there is no specific information available about dosage adjustments, safety concerns, or special precautions. This means that if you or a loved one is an older adult, it’s important to consult with a healthcare provider before starting the medication. They can help determine the best approach based on individual health needs and any other medications being taken. Always prioritize open communication with your healthcare team to ensure safe and effective treatment.

Renal Impairment

It appears that there is no specific information regarding renal impairment (kidney problems) in the provided text. Therefore, there are no dosage adjustments, special monitoring, or safety considerations to discuss for patients with kidney issues. If you have concerns about how your kidney health may affect your treatment, it's important to consult your healthcare provider for personalized advice and guidance.

Hepatic Impairment

If you have liver problems, it's important to know that there are no specific guidelines or dosage adjustments mentioned for your condition in the available information. This means that the standard recommendations for the medication do not change based on liver function. However, it’s always a good idea to discuss your liver health with your healthcare provider before starting any new medication. They can help ensure that your treatment is safe and effective for you.

Drug Interactions

It's great to know that there are no reported interactions between this medication and other drugs or laboratory tests. However, it's still very important to discuss all medications you are taking, including over-the-counter drugs and supplements, with your healthcare provider. This ensures that your treatment is safe and effective.

Always keep your healthcare provider informed about any changes in your health or new medications you may start. Open communication helps prevent any potential issues and supports your overall well-being.

Storage and Handling

To ensure the best performance of your product, store it at room temperature. This helps maintain its effectiveness and quality. Be aware that if the product is exposed to cold weather, it may temporarily become cloudy, but this does not affect its safety or function.

Handle the product with care, and always follow any additional instructions provided for safe use. If you have any concerns about its appearance or performance, consult the guidelines or reach out for assistance.

Additional Information

You should take this medication orally, twice a day, after brushing your teeth with toothpaste. If you are giving this medication to children under 12 years old, make sure to teach them good rinsing habits to help prevent swallowing the medication. It's also important to supervise them until they can use it on their own safely.

FAQ

What is LISTERINE® TOTAL CARE?

LISTERINE® TOTAL CARE is an anticavity fluoride mouthwash that aids in the prevention of dental cavities.

How does LISTERINE® TOTAL CARE work?

It contains Sodium Fluoride and Acidulated Phosphate, which help restore enamel, strengthen teeth, and kill 99.9% of germs, providing 24-hour cavity protection.

What are the benefits of using LISTERINE® TOTAL CARE?

It offers 6 benefits: aids in cavity prevention, restores enamel, strengthens teeth, freshens breath, cleans the whole mouth, and kills bad breath germs.

How should I use LISTERINE® TOTAL CARE?

Use it twice a day after brushing your teeth. Vigorously swish 10 mL (2 teaspoonfuls) for 1 minute and then spit it out. Do not swallow the rinse.

Can children use LISTERINE® TOTAL CARE?

Yes, children 6 years and older can use it, but they should be instructed in good rinsing habits and supervised until capable of using it without help. Consult a dentist for children under 6.

Are there any contraindications for LISTERINE® TOTAL CARE?

No contraindications are listed for LISTERINE® TOTAL CARE.

What should I do if I accidentally swallow LISTERINE® TOTAL CARE?

If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center immediately.

Is LISTERINE® TOTAL CARE safe during pregnancy or while nursing?

No specific information is provided regarding its use during pregnancy or nursing.

How should I store LISTERINE® TOTAL CARE?

Store it at room temperature. Cold weather may temporarily cloud the product.

Packaging Info

Below are the non-prescription pack sizes of Listerine Total Care Alcohol Free Anticavity Fluoride Mouthwash Fresh Mint (sodium fluoride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Listerine Total Care Alcohol Free Anticavity Fluoride Mouthwash Fresh Mint.
Details

Drug Information (PDF)

This file contains official product information for Listerine Total Care Alcohol Free Anticavity Fluoride Mouthwash Fresh Mint, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

This alcohol-free mouthwash provides 24-hour cavity protection and is formulated to kill 99.9% of germs. It contains sodium fluoride and acidulated phosphate as active ingredients, delivering anticavity benefits. The product is presented as a topical solution with a mild fresh mint flavor. LISTERINE® TOTAL CARE is available in a 1.0 L (1 Qt 1.8 Fl Oz) container.

Uses and Indications

This drug is indicated for the prevention of dental cavities.

There are no teratogenic effects associated with this drug. Additionally, no nonteratogenic effects have been reported.

Dosage and Administration

Adults and children aged 6 years and older are instructed to use the rinse twice daily, following brushing with toothpaste. The recommended method involves vigorously swishing 10 mL (2 teaspoonfuls) of the rinse between the teeth for a duration of 1 minute, after which the solution should be expectorated. It is imperative that the rinse is not swallowed. Additionally, patients should refrain from eating or drinking for 30 minutes post-rinsing to ensure optimal efficacy.

For children under 12 years of age, it is essential to instruct them in proper rinsing techniques to minimize the risk of swallowing the rinse. Supervision may be required until the child demonstrates the ability to use the rinse independently.

For children under 6 years of age, consultation with a dentist or physician is recommended prior to use.

Contraindications

Use is contraindicated if more than the recommended amount for rinsing is accidentally swallowed. In such cases, seek medical assistance or contact a Poison Control Center immediately.

Warnings and Precautions

It is imperative to keep this product out of the reach of children. In the event that more than the recommended amount used for rinsing is accidentally ingested, immediate medical assistance should be sought, or contact with a Poison Control Center is advised without delay.

Healthcare professionals should ensure that patients are aware of this critical warning to prevent accidental ingestion and potential harm.

Side Effects

Patients should be advised to keep the product out of reach of children. In the event that more than the recommended amount for rinsing is accidentally swallowed, it is imperative to seek medical assistance or contact a Poison Control Center immediately. This warning underscores the importance of proper usage and the potential risks associated with accidental ingestion.

Drug Interactions

No drug interactions or drug and laboratory test interactions have been identified in the available data. Therefore, no specific recommendations for dosage adjustments or monitoring are necessary at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Listerine Total Care Alcohol Free Anticavity Fluoride Mouthwash Fresh Mint (sodium fluoride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Listerine Total Care Alcohol Free Anticavity Fluoride Mouthwash Fresh Mint.
Details

Pediatric Use

Pediatric patients should be instructed to keep the product out of reach of children. In the event that more than the recommended amount for rinsing is accidentally swallowed, medical assistance or contact with a Poison Control Center is advised immediately.

For children aged 6 years and older, the product is indicated for use twice daily after brushing teeth with toothpaste. It is important to instruct children under 12 years of age in proper rinsing techniques to minimize the risk of swallowing. Supervision is recommended for children until they are capable of using the product without assistance.

For children under 6 years of age, consultation with a dentist or doctor is necessary prior to use.

Geriatric Use

There is no specific information regarding the use of this medication in geriatric patients, including dosage adjustments, safety concerns, or special precautions. Healthcare providers should exercise caution when prescribing this medication to elderly patients, as individual responses may vary. It is advisable to monitor these patients closely for any adverse effects or changes in efficacy.

Pregnancy

There is no specific information regarding the use of Listerine Total Care Alcohol Free Anticavity Fluoride Mouthwash during pregnancy. The drug insert does not provide safety concerns, dosage modifications, or special precautions for pregnant patients. Therefore, healthcare professionals should exercise caution and consider the lack of data when advising women of childbearing potential regarding the use of this product during pregnancy.

Lactation

There is no specific information available regarding the use of this medication in nursing mothers or any lactation considerations. Healthcare professionals should exercise caution and consider the potential risks and benefits when prescribing this medication to lactating mothers. The effects on breastfed infants have not been established.

Renal Impairment

There is no information available regarding dosage adjustments, special monitoring, or safety considerations for patients with renal impairment. Healthcare professionals should exercise caution and consider the lack of specific guidance when prescribing to patients with reduced kidney function.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there is no information available regarding dosage adjustments, special monitoring requirements, or precautions for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population.

Overdosage

In the event of an overdosage, immediate medical assistance is crucial. If an individual accidentally swallows more than the amount intended for rinsing, it is imperative to seek medical help or contact a Poison Control Center without delay.

Healthcare professionals should be aware that prompt intervention can significantly mitigate potential adverse effects associated with overdosage. Monitoring for symptoms related to the specific substance involved is essential, and appropriate management procedures should be initiated based on clinical judgment and established protocols.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the compound in these areas.

Postmarketing Experience

No postmarketing experience details are available in the insert text.

Patient Counseling

Healthcare providers should advise patients to keep the product out of reach of children to prevent accidental ingestion. Instruct patients that if more than the recommended amount used for rinsing is accidentally swallowed, they should seek medical help or contact a Poison Control Center immediately. It is important for patients to understand the potential risks associated with improper use and to act promptly in case of an emergency.

Storage and Handling

The product is supplied in various package configurations, with specific NDC numbers available for identification. It is essential to store the product at room temperature to maintain its integrity and effectiveness. In colder weather conditions, the product may temporarily cloud; however, this does not affect its quality or efficacy. Proper handling should ensure that the product is kept within the recommended temperature range to avoid any potential issues.

Additional Clinical Information

The medication is administered orally, with a recommended frequency of twice a day following brushing with toothpaste. Clinicians should instruct patients, particularly children under 12 years of age, on proper rinsing techniques to minimize swallowing, and supervision is advised until children are capable of using the product independently.

No additional information is available regarding laboratory tests, abuse potential, or postmarketing experience.

Drug Information (PDF)

This file contains official product information for Listerine Total Care Alcohol Free Anticavity Fluoride Mouthwash Fresh Mint, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Listerine Total Care Alcohol Free Anticavity Fluoride Mouthwash Fresh Mint, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

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Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.