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Listerine Total Care Mild Alcohol Free Anticavity Fluoride Mouthwash

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Active ingredient
Sodium Fluoride 0.1 mg/1 mL
Other brand names
Dosage form
Mouthwash
Route
Oral
Prescription status
OTC (over the counter)
Marketed in the U.S.
Since 2026
Label revision date
February 2, 2026
Active ingredient
Sodium Fluoride 0.1 mg/1 mL
Other brand names
Dosage form
Mouthwash
Route
Oral
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Marketed in the U.S.
Since 2026
Label revision date
February 2, 2026
Manufacturer
Kenvue Brands LLC
Registration number
M021
NDC root
69968-0951

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Drug Overview

LISTERINE® TOTAL CARE is an anticavity fluoride mouthwash designed to help you maintain good oral health. It works by preventing dental cavities and is powered by essential oils and fluoride, which together kill 99.9% of germs. This mouthwash not only strengthens your teeth and repairs enamel but also provides 24-hour cavity protection and freshens your breath.

With its unique formulation, LISTERINE® TOTAL CARE offers a comprehensive approach to oral hygiene, ensuring a clean and healthy mouth. By incorporating this mouthwash into your daily routine, you can enjoy the benefits of enhanced dental protection and a refreshing feeling throughout the day.

Uses

You can use this product to help prevent dental cavities, which are small holes in your teeth caused by decay. By incorporating it into your oral care routine, you can support your dental health and reduce the risk of developing these issues.

It's important to note that this product does not have any known harmful effects on developing babies (teratogenic effects) or any other non-harmful effects. This makes it a safe option for most users looking to maintain their oral hygiene.

Dosage and Administration

After brushing your teeth with toothpaste, you should use the mouth rinse twice a day. To do this, take 10 mL (which is about 2 teaspoonfuls) of the rinse and swish it vigorously between your teeth for one minute before spitting it out. It's important not to swallow the rinse. After using it, avoid eating or drinking anything for 30 minutes to allow the rinse to work effectively.

If you're helping children under 12, make sure to teach them how to rinse properly to prevent swallowing the rinse. You should supervise younger children until they can rinse without help. For children under 6 years old, it's best to consult a dentist or doctor before using the rinse.

What to Avoid

It's important to be aware of specific instructions regarding the use of this product. While there are no listed contraindications or concerns about abuse, misuse, or dependence, you should take care when using it. If you accidentally swallow more than what is intended for rinsing, seek medical help or contact a Poison Control Center immediately. Your safety is a priority, so please follow these guidelines closely.

Side Effects

It's important to keep this product out of reach of children. If a child accidentally swallows more than what is used for rinsing, seek medical help or contact a Poison Control Center immediately. This precaution helps ensure safety and prevent any potential harm.

Warnings and Precautions

It's important to keep this product out of reach of children. If you accidentally swallow more than what is intended for rinsing, seek medical help immediately or contact a Poison Control Center.

There are no specific general precautions or laboratory tests mentioned for this product, but always use it as directed to ensure your safety. If you have any concerns or experience unusual symptoms, don't hesitate to reach out to your healthcare provider.

Overdose

If you accidentally swallow more of this product than intended for rinsing, it’s important to seek medical help immediately or contact a Poison Control Center. Acting quickly can help ensure your safety.

Signs of an overdose may not be obvious, but if you experience any unusual symptoms after swallowing too much, don’t hesitate to reach out for assistance. Remember, it’s always better to be cautious when it comes to your health.

Pregnancy Use

When it comes to using Listerine Total Care Mild Alcohol Free Anticavity Fluoride Mouthwash during pregnancy, there is currently no specific information available about its safety, dosage adjustments, or any special precautions you should take. This means that the manufacturer has not provided guidance on how this mouthwash may affect you or your developing baby.

If you are pregnant or planning to become pregnant, it's always a good idea to consult with your healthcare provider before using any new products, including mouthwash. They can help you make informed decisions based on your individual health needs.

Lactation Use

If you are breastfeeding, you can feel reassured that there are no specific warnings or recommendations regarding the use of this product while nursing. Additionally, there is no information available about whether this product is excreted in breast milk or any potential risks it may pose to your infant. Always consult with your healthcare provider if you have any concerns or questions about medications while breastfeeding.

Pediatric Use

It's important to keep this product out of reach of children to ensure their safety. If a child accidentally swallows more than what is used for rinsing, seek medical help or contact a Poison Control Center immediately. For children aged 12 and older, the product can be used twice a day after brushing their teeth.

For younger children, especially those under 12, it's essential to teach them proper rinsing habits to reduce the chance of swallowing. Always supervise younger children until they can use the product safely on their own. If your child is under 6 years old, consult with a dentist or doctor before use.

Geriatric Use

When it comes to using this medication in older adults, there is no specific information available about dosage adjustments, safety concerns, or special precautions. This means that if you or a loved one is an older adult, it’s important to consult with a healthcare provider before starting the medication. They can help determine the best approach based on individual health needs and any other medications being taken. Always prioritize open communication with your healthcare team to ensure safe and effective treatment.

Renal Impairment

If you have kidney problems, it's important to know that there are no specific guidelines, dosage adjustments, or monitoring requirements mentioned for your condition in the provided information. This means that the standard recommendations for medication use may apply to you without any special considerations. However, always consult your healthcare provider for personalized advice and to ensure your treatment is safe and effective based on your kidney health.

Hepatic Impairment

If you have liver problems, it's important to know that the information provided does not include specific guidelines for dosage adjustments, special monitoring, or precautions related to your condition. This means that there are no tailored recommendations for how the medication may affect you differently due to your liver health.

Always consult your healthcare provider for personalized advice and to ensure that any treatment plan is safe and effective for your specific situation. They can help determine the best approach based on your liver function and overall health.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you.

Always feel free to ask questions and share your complete list of medications and any lab tests you may be undergoing. This way, you can receive the best possible care tailored to your needs.

Storage and Handling

To ensure the best performance of your product, store it at room temperature. This helps maintain its effectiveness and safety. When handling the product, be sure to follow any specific instructions provided to avoid contamination or damage. Always keep it in a clean environment to ensure it remains safe for use.

If you have any components that come with the product, make sure to understand how they fit into the overall use and safety guidelines. Proper storage and careful handling are key to ensuring that everything works as intended.

Additional Information

You should take this medication orally, twice a day, after brushing your teeth with toothpaste. If you have children under 12, it's important to teach them good rinsing habits to help prevent swallowing the medication. You should supervise younger children until they can use it safely on their own. For children under 6 years old, consult a dentist or doctor before use.

FAQ

What is LISTERINE® TOTAL CARE?

LISTERINE® TOTAL CARE is an anticavity fluoride mouthwash that aids in the prevention of dental cavities.

How does LISTERINE® TOTAL CARE work?

It is powered by essential oils and fluoride, kills 99.9% of germs, repairs enamel, strengthens teeth, and provides 24-hour cavity protection.

What is the recommended usage for adults and children 12 years and older?

Use twice a day after brushing your teeth with toothpaste, swishing 10 mL (2 teaspoonfuls) for 1 minute before spitting it out.

What should I do if more than the recommended amount is swallowed?

If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away.

Are there any contraindications for using LISTERINE® TOTAL CARE?

No contraindications are listed for this mouthwash.

Is LISTERINE® TOTAL CARE safe for children?

Children under 12 should be instructed in good rinsing habits, and those under 6 years of age should consult a dentist or doctor.

Can I use LISTERINE® TOTAL CARE during pregnancy?

There is no specific information regarding the use of this product during pregnancy.

What should I do if I have concerns about using LISTERINE® TOTAL CARE while nursing?

There are no specific warnings or recommendations regarding its use by nursing mothers.

How should LISTERINE® TOTAL CARE be stored?

Store LISTERINE® TOTAL CARE at room temperature.

Packaging Info

Below are the non-prescription pack sizes of Listerine Total Care Mild Alcohol Free Anticavity Fluoride Mouthwash (sodium fluoride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Listerine Total Care Mild Alcohol Free Anticavity Fluoride Mouthwash.
Details

Drug Information (PDF)

This file contains official product information for Listerine Total Care Mild Alcohol Free Anticavity Fluoride Mouthwash, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

Sodium Fluoride & Acidulated Phosphate Topical Solution is presented in a volume of 1.0 L (1 Qt 1.8 FL Oz).

Uses and Indications

This drug is indicated for the prevention of dental cavities.

There are no teratogenic effects associated with this drug. Additionally, no nonteratogenic effects have been reported.

Dosage and Administration

Adults and children aged 12 years and older are instructed to use the rinse twice daily, following brushing with a toothpaste. The recommended method involves vigorously swishing 10 mL (2 teaspoonfuls) of the rinse between the teeth for a duration of 1 minute, after which the solution should be expectorated. It is imperative that the rinse is not swallowed. Additionally, patients should refrain from eating or drinking for 30 minutes post-rinsing to ensure optimal efficacy.

For children under 12 years of age, it is essential to instruct them in proper rinsing techniques to minimize the risk of swallowing the rinse. Supervision is recommended until the child is capable of using the rinse independently. For children under 6 years of age, consultation with a dentist or physician is advised prior to use.

Contraindications

There are no contraindications listed for this product. However, it is important to note that if more than the recommended amount used for rinsing is accidentally swallowed, immediate medical assistance should be sought or contact with a Poison Control Center is advised.

Warnings and Precautions

It is imperative to keep this product out of the reach of children to prevent accidental ingestion. In the event that more than the recommended amount for rinsing is accidentally swallowed, immediate medical assistance should be sought. Healthcare professionals are advised to instruct patients to contact a Poison Control Center or seek emergency medical help without delay.

No specific general precautions or laboratory tests have been identified for this product. However, the emphasis on the potential risks associated with accidental ingestion underscores the importance of patient education regarding safe usage practices.

Side Effects

Patients should be advised to keep the product out of reach of children. In the event that more than the recommended amount used for rinsing is accidentally swallowed, it is imperative to seek medical assistance or contact a Poison Control Center immediately.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there is no information available regarding interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Listerine Total Care Mild Alcohol Free Anticavity Fluoride Mouthwash (sodium fluoride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Listerine Total Care Mild Alcohol Free Anticavity Fluoride Mouthwash.
Details

Pediatric Use

Pediatric patients should be instructed to keep the product out of reach of children. In the event that more than the recommended amount for rinsing is accidentally swallowed, immediate medical assistance or contact with a Poison Control Center is advised.

For efficacy, the product is indicated for use in adults and children aged 12 years and older, with a recommended dosage of twice daily following tooth brushing. Children under 12 years of age should be guided in proper rinsing techniques to minimize the risk of swallowing the product. Supervision is recommended for these children until they demonstrate the ability to use the product without assistance. For children under 6 years of age, consultation with a dentist or physician is necessary prior to use.

Geriatric Use

Elderly patients may not have specific information regarding the use of this medication, including dosage adjustments, safety concerns, or special precautions. Therefore, healthcare providers should exercise caution when prescribing this medication to geriatric patients. It is advisable to monitor these patients closely for any adverse effects or changes in therapeutic response, given the lack of targeted data for this population.

Pregnancy

There is no specific information available regarding the use of Listerine Total Care Mild Alcohol Free Anticavity Fluoride Mouthwash during pregnancy. As such, safety concerns, dosage modifications, or special precautions for pregnant patients have not been established in the provided drug insert. Healthcare professionals should consider the lack of data when advising women of childbearing potential and weigh the potential benefits against any unknown risks associated with the use of this product during pregnancy.

Lactation

There are no specific warnings or recommendations regarding the use of this product by lactating mothers. Additionally, there is no information available about the potential for excretion in breast milk or any associated risks to breastfed infants.

Renal Impairment

There is no information available regarding renal impairment, including dosage adjustments, special monitoring, or safety considerations for patients with reduced kidney function. Healthcare professionals should exercise caution and consider the lack of specific guidance when treating patients with renal impairment.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

In the event of an overdosage, immediate medical assistance is crucial. If an individual accidentally swallows more than the amount intended for rinsing, it is imperative to seek medical help or contact a Poison Control Center without delay.

Healthcare professionals should be aware that prompt intervention can significantly mitigate potential adverse effects associated with overdosage. Monitoring for symptoms and providing appropriate management based on clinical presentation is essential.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the ability to draw conclusions regarding the potential toxicological profile of the substance in nonclinical settings.

Postmarketing Experience

No postmarketing experience details are provided in the insert.

Patient Counseling

Healthcare providers should advise patients to keep the medication out of reach of children to prevent accidental ingestion. It is important to inform patients that if more than the recommended amount used for rinsing is accidentally swallowed, they should seek medical help or contact a Poison Control Center immediately. This guidance is crucial for ensuring patient safety and minimizing potential risks associated with accidental ingestion.

Storage and Handling

The product is supplied in various package configurations, with specific NDC numbers assigned for identification. It is essential to store the product at room temperature to maintain its integrity and efficacy. No special handling requirements are noted; however, standard precautions should be observed to ensure optimal storage conditions.

Additional Clinical Information

The medication is administered orally, with a recommended frequency of twice a day following brushing with toothpaste. Clinicians should instruct patients, particularly children under 12 years of age, on proper rinsing techniques to minimize swallowing. It is essential for caregivers to supervise younger children until they are capable of rinsing without assistance. For children under 6 years of age, consultation with a dentist or doctor is advised.

No additional information is available regarding laboratory tests, abuse potential, or postmarketing experience.

Drug Information (PDF)

This file contains official product information for Listerine Total Care Mild Alcohol Free Anticavity Fluoride Mouthwash, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Listerine Total Care Mild Alcohol Free Anticavity Fluoride Mouthwash, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

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Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.