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Major Arthritis Pain Relief Patch

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Active ingredients
  • Menthol 3 g/100 g
  • Methyl Salicylate 10 g/100 g
Other brand names
Dosage form
Patch
Route
Topical
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2023
Label revision date
February 18, 2026
Drug Information (PDF)
Prescribing information, PDF file
Active ingredients
  • Menthol 3 g/100 g
  • Methyl Salicylate 10 g/100 g
Other brand names
Dosage form
Patch
Route
Topical
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2023
Label revision date
February 18, 2026
Manufacturer
Major Pharmaceuticals
Registration number
M017
NDC root
0904-7342
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info (2 NDCs)
Packaging & NDC Codes (2)

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

The Major Arthritis Pain Relief Patch is designed to temporarily relieve mild to moderate aches and pains in your muscles and joints. It can be particularly helpful for conditions such as strains, sprains, simple backaches, arthritis, and bruises.

By applying the patch to the affected area, you can experience soothing relief from discomfort, allowing you to go about your daily activities with greater ease.

Uses

You can use this medication to temporarily relieve mild to moderate aches and pains in your muscles and joints. It is effective for various conditions, including strains, sprains, simple backaches, arthritis, and bruises. This means if you're dealing with discomfort from any of these issues, this medication may help ease your pain and improve your comfort.

It's important to note that there are no reported teratogenic effects (which means it doesn't cause birth defects) associated with this medication, so it is considered safe in that regard.

Dosage and Administration

If you are an adult aged 18 or older, you can use this medication by applying one patch at a time. Start by cleaning and drying the area of skin where you plan to place the patch. Once the skin is ready, remove the patch from its backing film and apply it directly to the skin. You should leave the patch in place for 8 to 12 hours. If your pain continues after using the first patch, you can apply a second patch for another 8 to 12 hours. However, make sure to remove the first patch before applying the new one.

It's important to remember that you should not use more than two patches in a single day, and you should not use the patches for more than three consecutive days. After using a patch, be sure to discard it properly and reseal the pouch to keep the remaining patches safe. If you are under 18 years old, this product is not suitable for you.

What to Avoid

It's important to use this medication safely. You should not apply it to your face, rashes, wounds, or any damaged skin. If you have an allergy to aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs), avoid using this product. Additionally, do not use it in combination with a heating pad or when you are sweating, such as during exercise or in hot conditions.

Make sure to discard any patch from a pouch that has been open for 14 days or more, and do not use it right before or after heart surgery. Following these guidelines will help ensure your safety and the effectiveness of the treatment.

Side Effects

If you are considering using this product, it's important to be aware of potential side effects. There is a risk of allergic reactions, especially if you are sensitive to aspirin or similar medications. Additionally, this product contains a nonsteroidal anti-inflammatory drug (NSAID), which may increase the chance of stomach bleeding. This risk is higher if you are over 60, have a history of stomach ulcers or bleeding, take blood thinners or steroids, consume alcohol regularly, or use other NSAIDs.

You should stop using the product and consult a doctor if you experience worsening stomach pain, faintness, vomiting blood, or notice black or bloody stools, as these could indicate stomach bleeding. Other reasons to seek medical advice include developing a rash or skin irritation, if your condition worsens, or if symptoms persist for more than three days or return shortly after improvement. Always consult a doctor before use if you have allergies to topical products, a history of stomach bleeding, or if you are taking certain medications for high blood pressure, heart disease, or kidney disease.

Warnings and Precautions

If you are allergic to aspirin or salicylates, please consult your doctor before using this product. Be aware that this medication contains a nonsteroidal anti-inflammatory drug (NSAID), which can increase the risk of stomach bleeding, especially if you are over 60, have a history of stomach ulcers or bleeding, take blood thinners or steroids, consume three or more alcoholic drinks daily, or use other NSAIDs. Always use the product as directed, and wash your hands after applying or removing the patch. Avoid contact with your eyes, and if it occurs, rinse thoroughly with water. Dispose of used patches safely, as they can still contain active medication that may harm children or pets.

Seek emergency medical help immediately if the patch is swallowed, or contact a Poison Control Center at 1-800-222-1222. You should stop using the product and call your doctor if you experience worsening stomach pain, faintness, vomiting blood, or notice bloody or black stools, as these may indicate stomach bleeding. Additionally, if you develop a rash or skin irritation, if your condition worsens, or if symptoms persist for more than three days or return shortly after clearing up, it’s important to reach out to your healthcare provider.

Overdose

It appears that there is no specific information available regarding overdosage for this medication. However, it's always important to be aware of the potential risks associated with taking any medication. If you suspect that you or someone else may have taken too much of a medication, look out for unusual symptoms such as extreme drowsiness, confusion, or difficulty breathing.

In the event of an overdose, it is crucial to seek immediate medical help. You can do this by calling your local emergency number or going to the nearest hospital. Always keep medications out of reach of children and follow the prescribed dosage to minimize the risk of an overdose. If you have any concerns or questions about your medication, don’t hesitate to reach out to your healthcare provider for guidance.

Pregnancy Use

It's important to consult your doctor before using this medication if you are breastfeeding or in the first six months of your pregnancy. This is to ensure the safety of both you and your baby during this critical time.

Additionally, you should avoid using this medication during the last three months of your pregnancy, as it may lead to complications for your unborn child or during delivery. Always prioritize open communication with your healthcare provider to make informed decisions about your health and your baby's well-being.

Lactation Use

If you are pregnant or breastfeeding, it’s important to consult your doctor before using any medication, especially during the first six months of pregnancy. This is to ensure the safety of both you and your baby.

Additionally, avoid using this medication during the last three months of pregnancy, as it may lead to complications for your unborn child or during delivery. Always prioritize open communication with your healthcare provider to make informed decisions about your health and your baby's well-being.

Pediatric Use

This product is not suitable for children under 18 years of age, so it's important to avoid using it for your child. If you have used a patch, make sure to dispose of it safely, away from children and pets, as even used patches can still contain the medication and may cause serious harm if chewed or ingested.

Always keep this product out of reach of children. If a child accidentally swallows it, seek medical help immediately or contact a Poison Control Center at 1-800-222-1222. Please note that the packaging is not designed to be child-resistant, so extra caution is necessary.

Geriatric Use

As you age, it's important to be aware that the risk of stomach bleeding increases if you are 60 years or older. This means that if you or a loved one falls into this age group, you should be particularly cautious about medications that may affect your stomach. Always consult with your healthcare provider about any medications you are taking, as they can help you understand the risks and make safer choices tailored to your needs.

Renal Impairment

It appears that there is no specific information regarding renal impairment (kidney problems) in the provided text. Therefore, there are no guidelines, dosage adjustments, or monitoring instructions to share for patients with kidney issues. If you have concerns about how your kidney health may affect your treatment, it's important to discuss this with your healthcare provider for personalized advice and recommendations.

Hepatic Impairment

If you have liver problems, it's important to know that there are no specific guidelines or dosage adjustments mentioned for your condition in the available information. This means that the standard recommendations apply, and there are no special monitoring requirements or precautions outlined for patients with liver impairment.

However, it's always best to discuss your individual health situation with your healthcare provider, as they can offer personalized advice and ensure that any medications you take are safe for your liver health.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you.

Always feel free to ask questions and share your complete list of medications and any lab tests you may be undergoing. This way, you can avoid any potential issues and receive the best care possible.

Storage and Handling

To ensure the best performance of your product, store it in a cool, dry place at a temperature between 20-25°C (68-77°F). It's important to keep it away from direct sunlight, as exposure can affect its quality. Additionally, make sure to protect the product from excessive moisture, which can also compromise its effectiveness.

When handling the product, always do so with clean hands and in a clean environment to maintain its integrity. Following these guidelines will help you use the product safely and effectively.

Additional Information

No further information is available.

FAQ

What is the Major Arthritis Pain Relief Patch used for?

The Major Arthritis Pain Relief Patch temporarily relieves mild to moderate aches and pains of muscles and joints associated with strains, sprains, simple backache, arthritis, and bruises.

Who should not use the Major Arthritis Pain Relief Patch?

Children under 18 years of age should not use this product. Additionally, do not use it on the face, rashes, wounds, or damaged skin.

How should I apply the patch?

Clean and dry the affected area, then remove the patch from the backing film and apply it to the skin. Leave it in place for up to 8 to 12 hours.

What should I do if my pain persists after using the patch?

If pain lasts after using the first patch, you may apply a second patch for another 8 to 12 hours, but do not use more than 2 patches per day.

What are the storage instructions for the patch?

Store the patch at 20-25°C (68-77°F), avoid direct sunlight, and protect it from excessive moisture.

What should I do if I experience side effects?

If you experience stomach pain, rash, or any worsening condition, stop using the patch and consult a doctor. Seek emergency help if you feel faint or vomit blood.

Can I use the patch if I am pregnant or breastfeeding?

Consult a doctor before use if you are pregnant, especially during the first 6 months, or if you are breastfeeding.

What precautions should I take while using the patch?

Use only as directed, wash your hands after applying or removing the patch, and avoid contact with eyes. Dispose of used patches away from children and pets.

What should I do if the patch is swallowed?

If swallowed, get medical help or contact a Poison Control Center immediately at 1-800-222-1222.

Packaging Info

Below are the non-prescription pack sizes of Major Arthritis Pain Relief Patch (menthol, methyl salicylate). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Major Arthritis Pain Relief Patch.
Details

Drug Information (PDF)

This file contains official product information for Major Arthritis Pain Relief Patch, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the specified drug.

Uses and Indications

This drug is indicated for the temporary relief of mild to moderate aches and pains in muscles and joints associated with strains, sprains, simple backache, arthritis, and bruises.

There are no teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

For adults aged 18 years and over, the recommended dosage involves the application of one patch at a time. Prior to application, the affected area must be cleaned and dried thoroughly. The patch should be removed from its backing film and applied directly to the skin. It is advised to leave the patch in place for a duration of 8 to 12 hours.

If pain persists after the initial application, a second patch may be applied for an additional 8 to 12 hours. It is essential to remove the used patch from the skin before applying a new one. The maximum usage is limited to two patches per day, and the product should not be used for more than three consecutive days. After a single use, the patch must be properly discarded, and the pouch should be resealed after opening to maintain integrity.

This product is not indicated for use in children under 18 years of age.

Contraindications

Use of this product is contraindicated in the following situations:

Application on the face or rashes is not recommended due to the potential for irritation. The product should not be applied to wounds or damaged skin, as this may exacerbate the condition or lead to adverse effects.

Patients with a known allergy to aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) should avoid use, as this may trigger an allergic reaction. The concurrent use of a heating pad is contraindicated due to the risk of increased absorption and potential for skin burns.

Application is also contraindicated during periods of sweating, such as from exercise or heat, as this may affect the product's efficacy and safety. Any patch from a pouch that has been open for 14 or more days should not be used, as the integrity and effectiveness of the product may be compromised.

Finally, the product should not be used immediately before or after heart surgery, as this may pose additional risks to the patient.

Warnings and Precautions

Patients with a known allergy to aspirin or salicylates should consult a healthcare professional prior to using this product.

The product contains a nonsteroidal anti-inflammatory drug (NSAID), which may increase the risk of stomach bleeding. Although the overall risk is low, certain factors can elevate this risk, including being 60 years of age or older, having a history of stomach ulcers or bleeding disorders, concurrent use of anticoagulants or steroid medications, taking other NSAIDs (such as aspirin, ibuprofen, or naproxen), consuming three or more alcoholic beverages daily while using this product, or exceeding the recommended duration or dosage of use.

It is imperative to use this product strictly as directed. Healthcare professionals should advise patients to wash their hands thoroughly after applying or removing the patch and to avoid contact with the eyes. In the event of eye contact, patients should rinse their eyes thoroughly with water. Used patches should be disposed of safely, out of reach of children and pets, as they still contain active drug substances that could lead to serious adverse effects if ingested.

Patients should be informed that the risk of heart attack or stroke may increase if the product is used in excess of the recommended dosage or for an extended period.

In case of accidental ingestion, immediate medical assistance should be sought, or the Poison Control Center (1-800-222-1222) should be contacted.

Patients are advised to discontinue use and contact their healthcare provider if they experience any of the following: worsening or persistent stomach pain or upset; fainting, vomiting blood, or passing bloody or black stools, which may indicate stomach bleeding; development of a rash, itching, or skin irritation; worsening of their condition; symptoms lasting longer than three days; or recurrence of symptoms after they have resolved.

Side Effects

Patients using this product should be aware of potential adverse reactions, particularly those related to serious conditions. There is a notable allergy alert for individuals who are prone to allergic reactions from aspirin or salicylates; such patients are advised to consult a healthcare professional prior to use.

The product contains a nonsteroidal anti-inflammatory drug (NSAID), which may increase the risk of stomach bleeding. While the overall chance of this occurring is small, certain factors can elevate this risk. These include being aged 60 years or older, having a history of stomach ulcers or bleeding problems, concurrent use of blood thinners (anticoagulants) or steroid medications, taking other NSAIDs (such as aspirin, ibuprofen, or naproxen), consuming three or more alcoholic drinks daily while using the product, or using it for longer than directed.

Patients should discontinue use and seek medical advice if they experience worsening stomach pain or upset, faintness, vomiting blood, or notice bloody or black stools, as these may indicate stomach bleeding. Additionally, the development of a rash, itching, or skin irritation warrants consultation with a healthcare provider. If symptoms persist for more than three days, worsen, or resolve only to recur within a few days, medical advice should also be sought.

Before using this product, patients should consult a doctor if they have known allergies to topical products, if the stomach bleeding warning applies to them, if they are taking diuretics, or if they have high blood pressure, heart disease, or kidney disease.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there are no known interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are necessary at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Major Arthritis Pain Relief Patch (menthol, methyl salicylate). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Major Arthritis Pain Relief Patch.
Details

Pediatric Use

Children under 18 years of age should not use this product. It is essential to keep the product out of reach of children, as used patches still contain the drug and can produce serious adverse effects if chewed or ingested. In the event of accidental ingestion, immediate medical assistance should be sought, or contact a Poison Control Center at 1-800-222-1222. Additionally, the packaging is not child-resistant, necessitating careful disposal of used patches away from children and pets.

Geriatric Use

Elderly patients, particularly those aged 60 years and older, may have an increased risk of stomach bleeding. Healthcare providers should exercise caution when prescribing medications that may exacerbate this risk in this population. It is advisable to closely monitor these patients for any signs of gastrointestinal bleeding and to consider appropriate dose adjustments or alternative therapies as necessary to ensure their safety.

Pregnancy

Pregnant patients are advised to consult a healthcare professional before using this medication, particularly during the first six months of pregnancy. The use of this medication is contraindicated during the last three months of pregnancy due to the potential risk of adverse effects on the unborn child and complications during delivery. Healthcare providers should carefully consider the benefits and risks when prescribing this medication to women of childbearing potential. Additionally, breastfeeding patients should also seek medical advice prior to use.

Lactation

Lactating mothers are advised to consult a healthcare professional before using this medication while breastfeeding, particularly during the first 6 months of pregnancy. It is important to note that the use of this medication is not recommended during the last 3 months of pregnancy due to potential risks to the unborn child and complications that may arise during delivery. There is no specific data available regarding the excretion of this medication in breast milk or its effects on breastfed infants. Therefore, caution is warranted when considering its use in lactating mothers.

Renal Impairment

There is no information available regarding dosage adjustments, special monitoring, or safety considerations for patients with renal impairment. Healthcare professionals should exercise caution and consider the lack of specific guidance when prescribing to patients with reduced kidney function.

Hepatic Impairment

There is no information available regarding the use of this medication in patients with hepatic impairment. Consequently, there are no dosage adjustments, special monitoring requirements, or precautions specified for individuals with compromised liver function. Healthcare professionals should exercise clinical judgment when considering the use of this medication in patients with liver problems, as the absence of specific guidance necessitates careful evaluation of the patient's overall health status and liver function.

Overdosage

There is currently no specific information available regarding overdosage for this medication. In the absence of documented overdosage data, healthcare professionals are advised to exercise caution and adhere to standard protocols for managing suspected cases of drug overdose.

In the event of an overdose, it is recommended that healthcare providers monitor the patient closely for any potential symptoms that may arise. General supportive measures should be implemented, including maintaining airway patency, ensuring adequate ventilation, and providing cardiovascular support as necessary.

If an overdose is suspected, immediate medical attention should be sought. Healthcare professionals may consider contacting a poison control center for guidance on the management of the situation. It is essential to document any symptoms observed and the actions taken in response to the overdose.

As there is no specific antidote or treatment protocol outlined for overdosage of this medication, the focus should remain on symptomatic and supportive care until further information becomes available.

Nonclinical Toxicology

The use of this product is contraindicated during the last trimester of pregnancy due to the potential for adverse effects on the developing fetus and complications during delivery. It is advised that individuals who are pregnant or breastfeeding consult a healthcare professional prior to use, particularly during the first six months of pregnancy.

No specific information regarding nonclinical toxicology or animal pharmacology and toxicology is available in the insert.

Postmarketing Experience

Postmarketing experience has identified the following adverse reactions reported voluntarily or through surveillance programs: rash, itching, and skin irritation. These events have been documented in the context of routine pharmacovigilance activities.

Patient Counseling

Patients should be advised to seek immediate medical assistance or contact a Poison Control Center at 1-800-222-1222 if the patch is swallowed, as the packaging is not child-resistant. It is essential to use the medication only as directed to ensure safety and efficacy.

Healthcare providers should instruct patients to wash their hands thoroughly after applying or removing the patch to prevent unintentional exposure. Patients must be cautioned to avoid contact with their eyes; in the event of eye contact, they should rinse the eyes thoroughly with water.

Additionally, patients should be informed about the proper disposal of used patches, emphasizing that they should be kept away from children and pets. Used patches still contain the drug product, which can lead to serious adverse effects if ingested by a child or pet.

Finally, it is important to communicate that the risk of heart attack or stroke may increase if the patient uses more than the recommended dose or for a longer duration than prescribed.

Storage and Handling

The product is supplied in various package configurations, with specific NDC numbers available upon request. It should be stored at a temperature range of 20-25°C (68-77°F). Care should be taken to avoid exposure to direct sunlight, and the product must be protected from excessive moisture to maintain its integrity and efficacy.

Additional Clinical Information

No further data are available.

Drug Information (PDF)

This file contains official product information for Major Arthritis Pain Relief Patch, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Major Arthritis Pain Relief Patch, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

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Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.