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Camphor (natural)/Capsaicin/Menthol, unspecified form/Methyl salicylate

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Active ingredients
  • Menthol, Unspecified Form 5 g/100 g – 100 mg/1 g
  • Capsaicin 0.01 g/100 g – 0.25 mg/1 g
  • Camphor (natural) 4 g/100 g – 31 mg/1 g
  • Methyl Salicylate 20 g/100 g – 150 mg/1 g
Reference brand
Pain Relief Cream Extra Strength
Dosage form
Cream
Route
Topical
Prescription status
OTC (over the counter)
Marketed in the U.S.
Since 2019
Label revision date
February 8, 2024
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Active ingredients
  • Menthol, Unspecified Form 5 g/100 g – 100 mg/1 g
  • Capsaicin 0.01 g/100 g – 0.25 mg/1 g
  • Camphor (natural) 4 g/100 g – 31 mg/1 g
  • Methyl Salicylate 20 g/100 g – 150 mg/1 g
Reference brand
Pain Relief Cream Extra Strength
Dosage form
Cream
Route
Topical
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Marketed in the U.S.
Since 2019
Label revision date
February 8, 2024
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Product Labels (2)
Product Labels (2)

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Drug Overview

Advil Targeted Relief is a pain-relieving cream designed to temporarily alleviate minor aches and pains in muscles and joints. It is effective for conditions such as arthritis, simple backache, muscle strains, bruises, sprains, and cramps. This cream contains four powerful pain-fighting ingredients and is intended for external use only.

While it shares a name with other Advil products, it does not contain the same active ingredient as traditional Advil formulations. This makes it a specialized option for targeted relief of specific types of pain.

Uses

You can use this cream to temporarily relieve minor aches and pains in your muscles and joints. It is effective for conditions such as arthritis, simple backache, muscle strains, bruises, sprains, and cramps. This product is designed to help you manage discomfort associated with these common issues, allowing you to feel more comfortable in your daily activities.

Dosage and Administration

You should use this cream only as directed. For adults and children aged 12 years and older, apply it to the affected area no more than 3 to 4 times a day. If the user is under 12 years old, it's important to consult a doctor before use. After applying the cream, make sure to wash your hands to avoid spreading the medication to other areas.

What to Avoid

You should avoid using this product on wounds or damaged skin, and do not apply it with a heating pad. If you are allergic to any ingredients in the product, do not use it. While using the cream, refrain from tightly bandaging the area. Additionally, keep the product out of reach of children, and if swallowed, seek medical help or contact a Poison Control Center immediately.

Side Effects

When using topical pain relief creams, you may experience some side effects. It's important to stop using the product and consult a doctor if your condition worsens, if symptoms last more than 7 days, or if you notice redness, rash, itching, or skin irritation. If you experience a severe burning sensation, discontinue use immediately.

These creams are for external use only, so avoid contact with your eyes and mucous membranes, and do not apply them to wounds or damaged skin. If you are pregnant or breastfeeding, consult a healthcare professional before use. Keep these products out of reach of children, and seek medical help if swallowed.

Warnings and Precautions

For external use only, this cream should not be applied to wounds, damaged, or irritated skin. Avoid contact with your eyes and mucous membranes; if contact occurs, rinse thoroughly with water. Do not use with a heating pad or bandage tightly. If you experience severe burning, stop using the product immediately.

You should stop using the cream and call your doctor if your condition worsens, if symptoms last longer than 7 days, or if you notice any rash, itching, or skin irritation. Additionally, seek emergency medical help if the cream is swallowed or if you have any concerns. Always consult your doctor if you have redness over the affected area or if you are allergic to any ingredients in the product.

Overdose

If you accidentally swallow Advil Targeted Relief cream, it's important to seek medical help immediately or contact a Poison Control Center. While there is no specific information about overdosage for Pain Relief Cream Extra Strength, it's always best to err on the side of caution.

Be aware of any unusual symptoms you may experience after using these products, and don't hesitate to reach out for help if you feel unwell.

Pregnancy Use

If you are pregnant or breastfeeding, it is important to consult a healthcare professional before using any pain relief creams, including Advil Targeted Relief and Pain Relief Cream Extra Strength. While specific safety concerns and dosage modifications are not detailed, seeking guidance from a medical expert can help ensure the safety of both you and your baby. Always prioritize open communication with your healthcare provider regarding any medications or treatments during this time.

Lactation Use

If you are breastfeeding, it is important to consult with a healthcare professional before using any medication, including topical creams like Advil Targeted Relief or Pain Relief Cream Extra Strength. While there is no specific information provided about the effects of these creams on nursing mothers or lactation, seeking guidance ensures the safety of both you and your baby. Always prioritize your health and your infant's well-being when considering any treatment.

Pediatric Use

For children under 12 years of age, it is important to consult your doctor before using any pain relief cream. If you have a child who is 12 years or older, they can apply the cream to the affected area up to 3 to 4 times daily. Always keep the cream out of reach of younger children, and if the cream is swallowed, seek medical help or contact a Poison Control Center immediately.

Geriatric Use

When using topical pain relief creams like Advil Targeted Relief or Pain Relief Cream Extra Strength, there is no specific information provided regarding their use in older adults. This means that there are no special dosage adjustments or safety concerns highlighted for elderly patients. However, as with any medication, it is always wise to consult with your healthcare provider before starting a new treatment, especially if you have underlying health conditions or are taking other medications. Your doctor can help ensure that the product is safe and appropriate for your individual needs.

Renal Impairment

When using Advil Targeted Relief or Pain Relief Cream Extra Strength, there is no specific information available regarding dosage adjustments or safety considerations for individuals with kidney problems. This means that if you have renal impairment, it’s important to consult your healthcare provider before using these products to ensure they are safe for you. Always prioritize your health and seek professional advice tailored to your situation.

Hepatic Impairment

You can use Advil Targeted Relief and Pain Relief Cream Extra Strength without specific concerns regarding liver issues, as there are no dosage adjustments or special monitoring requirements mentioned for individuals with liver problems. However, it's always a good idea to consult with your healthcare provider if you have any liver conditions or concerns before using these products.

Drug Interactions

You can use Advil Targeted Relief and Pain Relief Cream Extra Strength without worrying about drug interactions or interactions with laboratory tests, as no specific interactions have been reported for these products. However, it's always important to discuss any medications or treatments you are using with your healthcare provider. This ensures that you receive personalized advice and helps prevent any potential issues with your overall health and treatment plan.

Storage and Handling

To ensure the effectiveness of your pain relief cream, store it at room temperature, ideally between 20-25°C (68-77°F). Keep the container tightly closed to protect the cream from light and moisture. After opening, remember to discard the product when it is no longer needed to maintain safety and efficacy.

FAQ

What is Advil Targeted Relief?

Advil Targeted Relief is a pain-relieving cream designed to temporarily relieve minor aches and pains of muscles and joints.

What conditions can Advil Targeted Relief help with?

It can help relieve pain associated with arthritis, strains, simple backache, bruises, sprains, and cramps.

How should I use Advil Targeted Relief?

Apply to the affected area not more than 3 to 4 times daily for adults and children 12 years and older. Consult your doctor for children under 12.

Are there any precautions I should take?

Use only as directed, avoid contact with eyes and mucous membranes, and do not apply to wounds or damaged skin. If severe burning occurs, discontinue use immediately.

What should I do if I experience side effects?

Stop use and ask a doctor if your condition worsens, symptoms last more than 7 days, or if you develop a rash, itching, or skin irritation.

Can I use Advil Targeted Relief if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, consult a health professional before use.

What should I do if the cream gets in my eyes?

Avoid contact with eyes; if contact occurs, rinse thoroughly with water.

How should I store Advil Targeted Relief?

Store the cream at room temperature between 20-25°C (68-77°F), protect from light, and keep the container tightly closed.

What should I do if the cream is swallowed?

If swallowed, get medical help or contact a Poison Control Center right away.

Uses and Indications

This drug is indicated for the temporary relief of minor aches and pains of muscles and joints associated with the following conditions:

  • Arthritis

  • Simple backache

  • Muscle strains

  • Bruises

  • Sprains

  • Cramps

Limitations of Use: There are no teratogenic or nonteratogenic effects mentioned.

Dosage and Administration

Adults and children 12 years of age and older are instructed to apply the cream to the affected area not more than 3 to 4 times daily. For children under 12 years of age, consultation with a healthcare professional is recommended prior to use. It is essential to wash hands thoroughly after each application to prevent unintended contact with other areas of the body or with other individuals. Use the product only as directed.

Contraindications

Use of this product is contraindicated in individuals with known allergies to any of its ingredients. It should not be applied to wounds or damaged skin, as this may exacerbate the condition. Additionally, the product should not be used in conjunction with a heating pad due to the potential for increased irritation or adverse effects. Tight bandaging is also discouraged during use to prevent complications.

Warnings and Precautions

For external use only. Avoid contact with eyes and mucous membranes. If eye contact occurs, rinse thoroughly with water. If swallowed, get medical help or contact a Poison Control Center right away.

Serious Warnings

  • Do not use on wounds or damaged, broken, or irritated skin.

  • Do not use with a heating pad.

  • If severe burning sensation occurs, discontinue use immediately.

General Precautions

  • Use only as directed.

  • Do not use if allergic to any ingredients in this product.

  • Ask a doctor before use if there is redness over the affected area.

Stop Taking and Call Your Doctor

Stop use and ask a doctor if:

  • Condition worsens or if symptoms last for more than 7 days.

  • Symptoms clear up and occur again within a few days.

  • Rash, itching, or skin irritation develops.

  • Redness is present.

  • Irritation develops.

Side Effects

Patients using topical analgesic creams may experience a range of adverse reactions. The following information summarizes the potential side effects and warnings associated with the use of Advil Targeted Relief and Pain Relief Cream Extra Strength.

Serious Reactions

  • Severe burning sensation: If a severe burning sensation occurs, patients should discontinue use immediately and consult a healthcare professional.

Common Reactions

  • Rash, itching, or skin irritation: Patients are advised to stop use and seek medical advice if these symptoms develop.

  • Redness over the affected area: Patients should consult a doctor if redness is present or if the condition worsens.

General Warnings

  • Both products are for external use only. Patients should avoid contact with eyes and mucous membranes. In case of eye contact, thorough rinsing with water is recommended.

  • Patients should not apply the creams to wounds or damaged, broken, or irritated skin.

  • Tight bandaging of the area where the product is applied is not recommended.

  • The use of heating pads in conjunction with these products is contraindicated.

Precautions

  • Patients who are pregnant or breastfeeding should consult a healthcare professional before use.

  • The products should be kept out of reach of children. If swallowed, immediate medical help or contact with a Poison Control Center is necessary.

Recommendations for Use

  • Patients should use the products only as directed and should stop use if symptoms persist for more than 7 days or if symptoms clear up and then recur within a few days.

Drug Interactions

No specific drug interactions or laboratory test interactions have been identified for either Advil Targeted Relief or Pain Relief Cream Extra Strength. Both products indicate that there are no known interactions with other drugs or laboratory tests as per the provided information.

Pediatric Use

Children under 12 years of age should consult a doctor before using the product. For adults and children 12 years and older, the recommended application is to the affected area not more than 3 to 4 times daily. Care should be taken to keep the product out of reach of children, and in the event of ingestion, medical help or contact with a Poison Control Center is advised.

Geriatric Use

Elderly patients may use Advil Targeted Relief and Pain Relief Cream Extra Strength; however, there is no specific information regarding geriatric use, dosage adjustments, safety concerns, or special precautions provided in the drug inserts for these products. Healthcare professionals should exercise caution and consider individual patient factors when recommending these formulations to geriatric patients.

Pregnancy

If pregnant or breastfeeding, patients are advised to consult a healthcare professional before using Advil Targeted Relief or Pain Relief Cream Extra Strength. The available data does not specify safety concerns, dosage modifications, or special precautions related to the use of these products during pregnancy. Therefore, healthcare providers should exercise caution and consider individual patient circumstances when recommending these products to pregnant patients.

Lactation

Lactating mothers are advised to consult a healthcare professional before using Advil Targeted Relief or Pain Relief Cream Extra Strength. Currently, there is no specific information available regarding the excretion of these products in breast milk or their effects on breastfed infants. Therefore, caution is recommended when considering the use of these creams during lactation.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the available labeling for Advil Targeted Relief and Pain Relief Cream Extra Strength. Both products lack information regarding dosage adjustments, special monitoring, or safety considerations for individuals with reduced kidney function. Consequently, healthcare providers should exercise caution and consider the absence of guidance when prescribing these formulations to patients with renal impairment.

Hepatic Impairment

Patients with hepatic impairment have no specific dosage adjustments, monitoring requirements, or precautions outlined for the use of Advil Targeted Relief or Pain Relief Cream Extra Strength. The drug inserts for both products do not provide information regarding the safety or efficacy of these formulations in this patient population. Therefore, healthcare professionals should exercise caution and consider individual patient factors when prescribing these medications to patients with liver problems.

Overdosage

In the event of an overdose, immediate medical assistance should be sought. If the product is ingested, it is crucial to contact a Poison Control Center or seek medical help without delay.

While specific symptoms of overdose are not detailed in the available information, it is essential for healthcare professionals to monitor the patient for any unusual reactions or adverse effects following exposure. Prompt intervention and supportive care may be necessary based on the clinical presentation.

Nonclinical Toxicology

Teratogenicity

No information regarding teratogenic effects is available for the products evaluated.

Carcinogenesis, Mutagenesis, Impairment of Fertility

There is no data provided concerning carcinogenicity, mutagenicity, or impairment of fertility for the products assessed.

Animal Toxicology

No information is available regarding animal pharmacology and toxicology for the products evaluated.

Storage and Handling

Advil Targeted Relief and Pain Relief Cream Extra Strength are both supplied in cream form.

These products should be stored at room temperature, specifically between 20-25°C (68-77°F). It is important to protect the creams from light and ensure that the containers are kept tightly closed. Additionally, the products should be discarded after opening to maintain safety and efficacy.

Product Labels

The table below lists all over-the-counter labels containing camphor (natural), capsaicin, menthol, unspecified form, and methyl salicylate. Use it to compare dosage forms, strengths, and uses across products.

FDA-Approved Camphor, capsaicin, menthol, methyl salicylate Labels (Originator & Generics) showing branded and generic formulations with forms, routes, strengths, and FDA approval years.
More Details
Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It consolidates data from 2 FDA Structured Product Labels (DailyMed) for Camphor, Capsaicin, Menthol, Methyl Salicylate (marketed as Advil Targeted Relief, Pain Relief Cream Extra Strength), with data retrieved by a validated AI data-extraction workflow. This includes 2 distinct product formulations. All FDA-listed dosage forms and strengths are aggregated in the sections above. Regulatory status appears in the Summary Information panel and was verified in the FDA National Drug Code directory. Detailed product-specific information is available via the individual label pages linked above. No human clinician has reviewed this version.

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Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.