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Naturium Salicylic Acid Serum 2%

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Active ingredient
Salicylic Acid 20 mg/1 mL
Other brand names
Dosage form
Liquid
Route
Topical
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2022
Label revision date
November 14, 2025
Drug Information (PDF)
Prescribing information, PDF file
Active ingredient
Salicylic Acid 20 mg/1 mL
Other brand names
Dosage form
Liquid
Route
Topical
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2022
Label revision date
November 14, 2025
Manufacturer
e. l. f. Cosmetics, Inc
Registration number
M006
NDC root
76354-122
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info
Packaging & NDC Codes

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

This medication is designed to help you fight existing acne breakouts and prevent future ones. By targeting the underlying causes of acne, it works to keep your skin clearer and healthier over time. If you're struggling with acne, this treatment may be a helpful option to consider in your skincare routine.

Uses

If you're struggling with acne, this medication can be a helpful option for you. It works by not only fighting existing acne breakouts but also preventing future ones. This means you can achieve clearer skin and reduce the chances of new blemishes appearing.

Dosage and Administration

Before using this product, make sure to shake it well. Start by cleaning the skin thoroughly where you plan to apply it. You should then cover the entire affected area with a thin layer of the product. Initially, it’s best to apply it just once a day. If you find that your skin tolerates it well, you can gradually increase the application to two or three times daily, but only if needed or as your doctor advises.

Be mindful that excessive drying of the skin can happen, so if you experience bothersome dryness or peeling, reduce your application to once a day or even every other day. If you plan to go outside after applying the product, remember to use sunscreen to protect your skin. If you notice any irritation or sensitivity, stop using the product and consult your doctor.

What to Avoid

You should avoid applying this product to broken or irritated skin, as it can cause further irritation or complications. Additionally, be careful not to use it around your eyes. If the product accidentally gets into your eyes, rinse them gently and thoroughly with water to prevent discomfort. Always prioritize your safety and well-being when using any topical treatment.

Side Effects

When using this product, you may experience skin irritation and dryness, especially if you are using another topical acne treatment at the same time. To minimize these effects, it's best to use only one acne product at a time. Additionally, be careful to avoid the eye area; if the product accidentally gets into your eyes, rinse them gently and thoroughly with water. It's also important not to apply the product to broken or irritated skin, as this can worsen irritation. Remember, this product is for external use only.

Warnings and Precautions

This product is for external use only, so please avoid applying it to any areas that are not on the skin. If you are using another topical acne treatment, be cautious, as using both at the same time can increase the risk of skin irritation and dryness. If you experience irritation, it’s best to stop using one of the products.

Make sure to keep the product away from your eyes. If it accidentally gets into your eyes, rinse them gently and thoroughly with water. Additionally, do not apply the product to broken or irritated skin. If you accidentally swallow the product, seek medical help immediately.

Overdose

It appears that there is no specific information available regarding overdosage for this medication. However, it's important to be aware of the general signs of an overdose, which can include symptoms like extreme drowsiness, confusion, or difficulty breathing. If you suspect that you or someone else may have taken too much of a medication, it’s crucial to seek immediate medical help.

In case of an overdose, you should contact your local emergency services or go to the nearest hospital right away. Always keep the medication packaging on hand, as it can provide important information to healthcare professionals. Remember, it's better to be safe and get checked out if you have any concerns about an overdose.

Pregnancy Use

If you are pregnant or planning to become pregnant, it's important to know that there is no specific information available about the use of Naturium Salicylic Acid Serum 2% during pregnancy. This means that safety concerns, dosage adjustments, or any special precautions related to its use in pregnant individuals have not been addressed in the product's information.

Given this lack of guidance, it is advisable to consult with your healthcare provider before using this product to ensure it is safe for you and your baby. Your healthcare provider can help you weigh the potential risks and benefits based on your individual circumstances.

Lactation Use

If you are breastfeeding, you can feel reassured that there are no specific warnings or recommendations regarding the use of this product while nursing. Additionally, there is no information available about whether this product is excreted in breast milk or any potential risks to your infant associated with its use during lactation. Always consult with your healthcare provider if you have any concerns or questions about medications while breastfeeding.

Pediatric Use

It's important to keep this medication out of reach of children. If your child accidentally swallows it, seek medical help immediately.

When using this product on your child's skin, start with one application each day. You can gradually increase to two or three times a day if necessary or as directed by your child's doctor. Be mindful that excessive drying of the skin may occur. If you notice any bothersome dryness or peeling, reduce the application to once a day or every other day.

Geriatric Use

While there is no specific information about the use of Naturium Salicylic Acid Serum 2% in older adults, it's always wise to approach new products with caution. If you or a loved one is considering using this serum, it's important to monitor for any unusual reactions or side effects, especially since older skin can be more sensitive.

Since the drug insert does not mention any dosage adjustments or special precautions for elderly patients, you may want to consult with a healthcare professional before starting the serum. This can help ensure that it fits well with any other treatments or medications you may be using.

Renal Impairment

There are no specific guidelines, dosage adjustments, or monitoring requirements mentioned for patients with kidney problems in the provided information. If you have renal impairment (kidney issues), it's important to consult your healthcare provider for personalized advice and to ensure your treatment is safe and effective. Always keep your doctor informed about your kidney health, as they may need to adjust your medications or monitor you more closely.

Hepatic Impairment

If you have liver problems, it's important to know that there are no specific guidelines or dosage adjustments mentioned for your condition in the provided information. This means that the usual recommendations for monitoring or precautions related to liver function are not detailed.

Always consult your healthcare provider for personalized advice and to ensure that any medications you take are safe for your liver health. They can provide guidance tailored to your specific situation.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you. Always share your complete list of medications and any health conditions you have to receive the best care possible.

Storage and Handling

To ensure the best performance and safety of your product, store it in a controlled environment with temperatures between 4-20°C (39-68°F). It's important to keep the product in a dark and dry place, away from direct sunlight and moisture. Always make sure the container is tightly closed to prevent contamination and maintain its effectiveness.

When handling the product, be mindful of these storage conditions to avoid any potential issues. Proper storage and handling will help you use the product safely and effectively.

Additional Information

When using this product for the first time, it's important to perform a sensitivity test. Apply a small amount to one or two affected areas for the first three days. If you experience no discomfort, you can continue using it as directed.

Make sure to store the product in a controlled environment, ideally between 4-20°C (39-68°F), and keep it in a dark, dry place. Always ensure the container is tightly closed to maintain its effectiveness.

FAQ

What is the main purpose of this product?

This product helps fight existing acne breakouts and prevents future acne breakouts.

How should I apply this product?

Clean the skin thoroughly before applying a thin layer to the affected area one to three times daily.

What should I do if my skin becomes dry or irritated?

If you experience bothersome dryness or peeling, reduce application to once a day or every other day.

Can I use this product if I have broken or irritated skin?

No, you should not apply this product to broken or irritated skin.

Is this product safe for external use?

Yes, this product is for external use only.

What precautions should I take when using this product?

Avoid the eye area, and if contact occurs, flush gently with water. If irritation occurs, use only one acne product at a time.

What should I do if I swallow this product?

If swallowed, seek medical help immediately.

How should I store this product?

Store in controlled temperatures (4-20°C/39-68°F), in a dark and dry place, and keep the container tightly closed.

Is there any information regarding the use of this product during pregnancy or lactation?

There is no specific information provided regarding the use of this product during pregnancy or lactation.

What should I do if I am a new user?

Perform a sensitivity test by applying the product sparingly to one or two small affected areas for the first 3 days.

Packaging Info

Below are the non-prescription pack sizes of Naturium Salicylic Acid Serum 2% (salicylic acid). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Naturium Salicylic Acid Serum 2%.
Details

Drug Information (PDF)

This file contains official product information for Naturium Salicylic Acid Serum 2%, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the specified drug.

Uses and Indications

This drug is indicated for the treatment of existing acne breakouts and for the prevention of future acne breakouts. It is intended for use in individuals seeking to manage acne effectively.

Dosage and Administration

The product should be shaken well before use. Prior to application, the skin must be cleaned thoroughly. A thin layer of the product should be applied to the entire affected area one to three times daily. It is recommended to initiate treatment with one application per day, gradually increasing to two or three times daily as needed or as directed by a healthcare professional.

In cases where excessive drying of the skin occurs, the frequency of application should be reduced to once daily or every other day. If the patient experiences bothersome dryness or peeling, it is advisable to decrease the application frequency accordingly.

For patients who will be exposed to sunlight, it is important to apply sunscreen after using this product. Should any irritation or sensitivity develop, the patient should discontinue use and consult a healthcare professional.

Contraindications

Application is contraindicated on broken or irritated skin. Additionally, the product should not be applied to the eye area; in the event of eye contact, it is essential to flush the eyes gently and thoroughly with water.

Warnings and Precautions

For external use only. Healthcare professionals should advise patients that the product is intended solely for topical application.

Skin irritation and dryness may be exacerbated when used concurrently with other topical acne treatments. It is recommended that patients use only one acne product at a time to minimize the risk of irritation.

Care should be taken to avoid contact with the eye area. In the event of accidental eye contact, patients should be instructed to flush the eyes gently and thoroughly with water. Additionally, the product should not be applied to broken or irritated skin to prevent further complications.

In cases of accidental ingestion, immediate medical assistance should be sought.

Side Effects

Patients using this product may experience skin irritation and dryness, particularly when used concurrently with other topical acne treatments. It is advised that if irritation occurs, patients should limit the use to one acne product at a time to minimize adverse reactions.

This product is intended for external use only. Care should be taken to avoid contact with the eye area; in the event of eye contact, it is recommended to flush the area gently and thoroughly with water. Additionally, the product should not be applied to broken or irritated skin to prevent exacerbation of adverse effects.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there is no information available regarding interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Naturium Salicylic Acid Serum 2% (salicylic acid). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Naturium Salicylic Acid Serum 2%.
Details

Pediatric Use

Pediatric patients should be monitored closely when using this medication. It is essential to keep the product out of reach of children, and if swallowed, medical assistance should be sought immediately.

To minimize the risk of excessive skin drying, it is recommended to initiate treatment with one application daily. The frequency may be gradually increased to two or three times daily as needed or as directed by a healthcare professional. Should any bothersome dryness or peeling occur, the application frequency should be reduced to once a day or every other day.

Geriatric Use

Elderly patients may not have specific information regarding the use of Naturium Salicylic Acid Serum 2%. The prescribing information does not provide guidance on dosage adjustments, safety concerns, or special precautions for this population. Therefore, healthcare providers should exercise caution when considering the use of this product in geriatric patients, as individual responses may vary. Monitoring for any adverse effects or unusual reactions is advisable when administering this serum to elderly individuals.

Pregnancy

There is no specific information regarding the use of Naturium Salicylic Acid Serum 2% in pregnant patients. The drug insert does not provide safety concerns, dosage modifications, or special precautions for use during pregnancy. Therefore, healthcare professionals should exercise caution when considering this product for women of childbearing potential and weigh the potential risks and benefits. It is advisable to discuss any concerns with patients and consider alternative treatments that have established safety profiles during pregnancy.

Lactation

There are no specific warnings or recommendations regarding the use of this product in nursing mothers. Additionally, there is no information available about the potential for excretion in breast milk or any associated risks to breastfed infants during lactation.

Renal Impairment

There is no information available regarding dosage adjustments, special monitoring, or safety considerations for patients with renal impairment. Healthcare professionals should exercise caution and consider the lack of specific guidance when prescribing to patients with reduced kidney function.

Hepatic Impairment

There is no information available regarding the use of this medication in patients with hepatic impairment. Consequently, there are no dosage adjustments, special monitoring requirements, or precautions specified for individuals with compromised liver function. Healthcare professionals should exercise caution and consider the lack of data when prescribing this medication to patients with liver problems.

Overdosage

In the absence of specific overdosage information, it is essential for healthcare professionals to remain vigilant and prepared for potential scenarios involving overdose.

Healthcare providers should be aware that the clinical presentation of an overdose may vary depending on the substance involved and the individual patient’s characteristics. Symptoms of overdose can range from mild to severe and may include altered mental status, cardiovascular instability, respiratory distress, and gastrointestinal disturbances.

In the event of suspected overdosage, immediate medical evaluation is recommended. Healthcare professionals should assess the patient's vital signs and conduct a thorough clinical examination. Supportive care should be initiated as necessary, including airway management, oxygen supplementation, and intravenous fluids.

If specific antidotes or treatments are available for the substance involved, they should be administered according to established protocols. Continuous monitoring of the patient’s condition is crucial, and appropriate laboratory tests may be warranted to guide further management.

In all cases of suspected overdose, it is advisable to contact a poison control center or consult relevant clinical guidelines for additional support and recommendations tailored to the specific situation.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the use of the compound in these contexts.

Postmarketing Experience

No postmarketing experience details are available for NATURIUM SALICYLIC ACID SERUM 2%.

Patient Counseling

Healthcare providers should advise patients to seek medical help immediately if the product is swallowed. It is important to inform patients that using this product in conjunction with other topical acne treatments may increase the likelihood of skin irritation and dryness. Therefore, if patients experience any irritation, they should be instructed to use only one acne product at a time to minimize adverse effects.

Patients should also be cautioned to avoid applying the product to the eye area. In the event of accidental eye contact, they should flush the eyes gently and thoroughly with water. Additionally, healthcare providers should emphasize that the product should not be applied to broken or irritated skin to prevent further complications.

Storage and Handling

The product is supplied in a container that must be stored in controlled temperatures ranging from 4 to 20°C (39 to 68°F). It is essential to keep the product in a dark and dry place to maintain its integrity. Additionally, the container should be kept tightly closed to prevent contamination and ensure stability.

Additional Clinical Information

Patients should undergo a sensitivity test when using the product for the first time. It is recommended to apply the product sparingly to one or two small affected areas over the initial three days. If no discomfort is experienced, patients may proceed with the standard application instructions.

Clinicians should advise that the product be stored in controlled temperatures ranging from 4-20°C (39-68°F) and kept in a dark, dry place. The container should remain tightly closed to maintain product integrity.

Drug Information (PDF)

This file contains official product information for Naturium Salicylic Acid Serum 2%, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Naturium Salicylic Acid Serum 2%, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

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Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.