ADD CONDITION

items per page

Neutrogena Evenly Clear Acne Exfoliant

Last content change checked dailysee data sync status

Active ingredient
Salicylic Acid 5 mg/1 mL
Other brand names
Dosage form
Lotion
Route
Topical
Prescription status
OTC (over the counter)
Marketed in the U.S.
Since 2025
Label revision date
September 26, 2025
Active ingredient
Salicylic Acid 5 mg/1 mL
Other brand names
Dosage form
Lotion
Route
Topical
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Marketed in the U.S.
Since 2025
Label revision date
September 26, 2025
Manufacturer
Kenvue Brands LLC
Registration number
M006
NDC root
69968-0944

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

Neutrogena® Evenly Clear™ is a multi-acid serum designed to help treat acne and improve the appearance of your skin. This product contains salicylic acid, which is effective in treating acne by unclogging pores, as well as 2.5% mandelic acid and 2.5% PHA (polyhydroxy acid) exfoliant, both of which work to gently exfoliate the skin. By exfoliating, this serum helps to visibly fade the look of post-acne marks, promoting a clearer and more even skin tone.

Recommended by dermatologists, Neutrogena® Evenly Clear™ comes in a convenient 30 mL bottle, making it easy to incorporate into your skincare routine. If you're looking for a solution to help manage acne and improve your skin's overall appearance, this serum may be a beneficial option for you.

Uses

If you're dealing with acne, this medication is designed specifically to help treat this common skin condition. Acne can be frustrating, but with the right treatment, you can see improvements in your skin's appearance and health.

It's important to note that this medication does not have any known teratogenic effects (which means it doesn't cause birth defects) or nonteratogenic effects. This makes it a safer option for those concerned about potential risks while seeking effective acne treatment.

Dosage and Administration

Before you start using this product, make sure to clean the affected area of your skin thoroughly. Once your skin is clean, apply a thin layer of the product to the entire affected area. You can do this one to three times a day, depending on your needs and what your doctor recommends.

To avoid excessive drying of your skin, it’s best to start with just one application each day. If your skin tolerates it well, you can gradually increase to two or three applications daily. However, if you notice any bothersome dryness or peeling, reduce your application to once a day or even every other day. This way, you can find the right balance that works for your skin.

What to Avoid

It's important to use this product safely. Keep it out of reach of children to prevent accidental ingestion. If someone swallows it, seek medical help or contact a Poison Control Center immediately. Additionally, avoid letting the product come into contact with your eyes; if it does, flush your eyes with water right away.

While there are no specific contraindications or concerns about abuse, misuse, or dependence associated with this product, following these precautions will help ensure your safety and well-being.

Side Effects

When using this product, you may experience skin irritation and dryness, especially if you are using another topical acne medication at the same time. To minimize irritation, it’s best to use only one topical acne treatment at a time. Be careful to avoid contact with your eyes; if this happens, rinse your eyes with water immediately.

This product is for external use only. If you accidentally swallow it, seek medical help or contact a Poison Control Center right away.

Warnings and Precautions

This medication is for external use only, so please avoid applying it to any areas other than your skin. If you are using another topical acne treatment, be cautious, as using both at the same time can increase the risk of skin irritation and dryness. If you experience irritation, it’s best to stop using one of the products.

Make sure to keep this medication out of reach of children. If a child accidentally swallows it, seek medical help or contact a Poison Control Center immediately. Additionally, be careful to avoid contact with your eyes; if this happens, flush your eyes with water right away.

Overdose

If you or someone else has swallowed too much of a medication, it’s important to seek medical help immediately. You can do this by contacting a Poison Control Center or going to the nearest emergency room. Acting quickly can make a significant difference in the outcome.

Signs of an overdose can vary, but they may include unusual drowsiness, confusion, or difficulty breathing. If you notice any of these symptoms, don’t hesitate to get help right away. Remember, it’s always better to be safe and get checked by a medical professional.

Pregnancy Use

If you are pregnant or planning to become pregnant, it's important to know that there are no specific warnings or precautions regarding the use of this product during pregnancy. However, since the product is not explicitly mentioned in relation to pregnancy, it’s always best to consult with your healthcare provider before using any medication. They can provide personalized advice based on your health and pregnancy status to ensure the safety of you and your baby.

Lactation Use

If you are breastfeeding, you can use this product without specific warnings or recommendations against it. Currently, there is no information available about whether this product passes into breast milk or if it poses any risk to your infant.

As always, it's a good idea to consult with your healthcare provider if you have any concerns or questions about using medications while nursing.

Pediatric Use

It's important to keep this medication out of reach of children. If a child accidentally swallows it, you should seek medical help immediately or contact a Poison Control Center. Taking quick action can help ensure their safety. Always be vigilant and store medications securely to prevent any accidents.

Geriatric Use

While there is no specific information about the use of Neutrogena Evenly Clear Acne Exfoliant in older adults, it's important to approach any new skincare product with caution. Since the drug insert does not mention dosage adjustments or safety concerns for elderly patients, you should consider consulting with a healthcare professional before starting this product. This is especially true if you have any existing skin conditions or are taking other medications that could affect your skin's sensitivity.

Always pay attention to how your skin reacts to new products, and if you notice any irritation or unusual changes, discontinue use and seek advice from a healthcare provider. Your skin may have different needs as you age, so prioritizing gentle and effective skincare is key.

Renal Impairment

It appears that there is no specific information regarding renal impairment (kidney problems) in the provided text. Therefore, there are no dosage adjustments, special monitoring, or safety considerations to discuss for patients with kidney issues. If you have concerns about how your kidney health may affect your treatment, it's important to consult your healthcare provider for personalized advice and guidance.

Hepatic Impairment

If you have liver problems, it's important to know that there are no specific guidelines or dosage adjustments mentioned for your condition in the provided information. This means that the standard recommendations apply, but you should always consult your healthcare provider for personalized advice. They can help determine the best approach for your treatment and monitor your liver function as needed.

Make sure to keep your doctor informed about your liver health, as they may need to conduct liver function tests (which check how well your liver is working) and adjust your treatment accordingly. Your safety and well-being are the top priority, so don't hesitate to ask questions or express any concerns you may have.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. Currently, there are no specific drug interactions or laboratory test interactions noted for this medication. However, every individual is different, and your healthcare provider can help ensure that your treatment is safe and effective based on your unique health needs. Always feel free to ask questions and share all the medications and supplements you are using to avoid any potential issues.

Storage and Handling

To ensure the best performance of your product, store it at room temperature. This means keeping it in a place that is neither too hot nor too cold, typically between 68°F to 77°F (20°C to 25°C).

When handling the product, make sure to do so with clean hands or while using gloves to maintain hygiene. This helps prevent contamination and ensures safety during use. Always follow any specific disposal instructions provided to ensure safe and responsible disposal of the product.

Additional Information

You should apply this product topically, covering the entire affected area with a thin layer one to three times a day. It's best to start with one application daily and then gradually increase to two or three times daily if needed or as directed by your doctor.

Be aware that this product contains an alpha hydroxy acid (AHA), which can make your skin more sensitive to the sun, increasing the risk of sunburn. To protect yourself, use sunscreen, wear protective clothing, and limit your sun exposure while using this product and for a week after you stop using it.

FAQ

What is Neutrogena® Evenly Clear™?

Neutrogena® Evenly Clear™ is an acne exfoliant, multi-acid serum that contains Salicylic Acid, 2.5% Mandelic Acid, and 2.5% PHA Exfoliant.

How should I use this product?

Clean your skin thoroughly before applying a thin layer to the affected area one to three times daily. Start with one application daily and gradually increase if needed.

What should I do if I experience dryness or irritation?

If you experience bothersome dryness or peeling, reduce application to once a day or every other day.

Are there any contraindications for using this product?

There are no contraindications listed for Neutrogena® Evenly Clear™.

Is this product safe for use during pregnancy?

There are no explicit warnings or precautions regarding the use of this product during pregnancy.

Can nursing mothers use this product?

There are no specific warnings or recommendations regarding the use of this product by nursing mothers.

What precautions should I take while using this product?

Avoid contact with eyes and keep out of reach of children. If swallowed, seek medical help immediately.

Does this product have any known drug interactions?

No drug interactions information is provided for Neutrogena® Evenly Clear™.

How should I store this product?

Store Neutrogena® Evenly Clear™ at room temperature.

What should I do if I experience skin irritation?

If skin irritation occurs, only use one topical acne medication at a time to avoid increased irritation.

Packaging Info

Below are the non-prescription pack sizes of Neutrogena Evenly Clear Acne Exfoliant (salicylic acid). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Neutrogena Evenly Clear Acne Exfoliant.
Details

Drug Information (PDF)

This file contains official product information for Neutrogena Evenly Clear Acne Exfoliant, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the specified drug.

Uses and Indications

This drug is indicated for the treatment of acne.

There are no teratogenic effects associated with this medication. Additionally, no nonteratogenic effects have been reported.

Dosage and Administration

Healthcare professionals should ensure that the skin is thoroughly cleaned prior to the application of this product. The recommended application involves covering the entire affected area with a thin layer. This can be done one to three times daily, depending on the patient's needs and the physician's guidance.

It is advisable to initiate treatment with one application per day to minimize the risk of excessive drying of the skin. Based on the patient's response, the frequency may be gradually increased to two or three times daily as necessary or as directed by a healthcare provider.

In cases where bothersome dryness or peeling occurs, it is recommended to reduce the frequency of application to once a day or every other day to alleviate these symptoms.

Contraindications

Use is contraindicated in the following situations:

  • The product should be kept out of reach of children to prevent accidental ingestion.

  • In the event of accidental swallowing, immediate medical assistance or contact with a Poison Control Center is required.

  • Contact with eyes must be avoided; if contact occurs, the eyes should be flushed immediately with water.

Warnings and Precautions

For external use only. Healthcare professionals should advise patients that the application of this product may lead to skin irritation and dryness, particularly if used concurrently with other topical acne medications. In cases where irritation is observed, it is recommended that patients limit their use to one topical acne medication at a time to mitigate adverse effects.

It is imperative to avoid contact with the eyes. Should contact occur, patients must be instructed to immediately flush the affected area with water to prevent further irritation or damage.

Additionally, this product should be kept out of reach of children. In the event of accidental ingestion, it is crucial to seek medical assistance or contact a Poison Control Center without delay to ensure appropriate care is provided.

Side Effects

Patients using this product may experience skin irritation and dryness, particularly if another topical acne medication is used concurrently. It is advised that only one topical acne medication be applied at a time to minimize the risk of irritation.

In addition, patients should avoid contact with the eyes. Should contact occur, it is imperative to flush the eyes immediately with water to mitigate potential adverse effects.

This product is intended for external use only. In the event of accidental ingestion, patients should seek medical assistance or contact a Poison Control Center without delay.

Drug Interactions

There are currently no documented drug interactions associated with the use of this medication. Additionally, there is no information available regarding interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Neutrogena Evenly Clear Acne Exfoliant (salicylic acid). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Neutrogena Evenly Clear Acne Exfoliant.
Details

Pediatric Use

Pediatric patients should be advised to keep this medication out of reach of children. In the event of accidental ingestion, immediate medical assistance should be sought, or the Poison Control Center should be contacted without delay.

Geriatric Use

There is no specific information regarding the use of Neutrogena Evenly Clear Acne Exfoliant in geriatric patients. The prescribing information does not provide details on dosage adjustments, safety concerns, or special precautions that may be necessary for elderly patients. Therefore, healthcare providers should exercise caution and consider individual patient factors when recommending this product to geriatric patients, as the absence of specific data necessitates careful monitoring and assessment of treatment outcomes in this population.

Pregnancy

The product has not been specifically studied in pregnant patients, and there are no explicit warnings or precautions regarding its use during pregnancy in the available data. As such, the potential risks to fetal outcomes remain unclear. Healthcare professionals should consider the lack of data when prescribing this product to women of childbearing potential and weigh the benefits against any potential risks. It is advisable to monitor pregnant patients closely if the product is deemed necessary for use during pregnancy.

Lactation

There are no specific warnings or recommendations regarding the use of this product by lactating mothers. Additionally, there is no information available about the potential for excretion in breast milk or any associated risks to breastfed infants during the use of this product.

Renal Impairment

There is no information available regarding renal impairment, dosage adjustments, special monitoring, or safety considerations for patients with reduced kidney function. Healthcare professionals should exercise caution and consider individual patient factors when treating patients with renal impairment, as specific guidelines or recommendations are not provided in the current data.

Hepatic Impairment

There is no information available regarding the use of this medication in patients with hepatic impairment. Consequently, there are no dosage adjustments, special monitoring requirements, or precautions specified for individuals with compromised liver function. Healthcare professionals should exercise caution and consider the individual patient's liver status when prescribing this medication.

Overdosage

In the event of an overdosage, immediate medical assistance is crucial. If the substance is ingested, healthcare professionals should advise patients or caregivers to seek medical help or contact a Poison Control Center without delay.

Prompt intervention is essential to mitigate potential adverse effects associated with overdosage. Symptoms may vary depending on the specific substance involved, and healthcare providers should be prepared to assess and manage these symptoms accordingly.

Management procedures may include supportive care and symptomatic treatment, tailored to the individual patient's needs. Continuous monitoring and evaluation are recommended to ensure patient safety and effective resolution of any complications arising from the overdosage.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data in these areas limits the understanding of the compound's potential effects in nonclinical settings.

Postmarketing Experience

No postmarketing experience details are available in the insert.

Patient Counseling

Healthcare providers should advise patients to keep the medication out of reach of children to prevent accidental ingestion. In the event of swallowing the medication, patients should seek medical assistance or contact a Poison Control Center immediately.

Patients should be informed that the use of this medication may lead to skin irritation and dryness, particularly if they are using another topical acne medication concurrently. It is recommended that patients use only one topical acne medication at a time to minimize the risk of irritation.

Additionally, healthcare providers should instruct patients to avoid contact with the eyes. If contact occurs, patients should be advised to flush the eyes immediately with water to mitigate any potential irritation.

Storage and Handling

The product is supplied in various package configurations, with specific NDC numbers available for identification. It is essential to store the product at room temperature to maintain its integrity and efficacy. No special handling requirements are noted; however, standard precautions should be observed to ensure optimal storage conditions.

Additional Clinical Information

The product is administered topically, with a recommended application of a thin layer to the entire affected area one to three times daily. Patients should begin with one application daily and may gradually increase to two or three times daily as needed or as directed by a healthcare professional.

Clinicians should counsel patients regarding sun exposure, as the product contains an alpha hydroxy acid (AHA), which may heighten skin sensitivity to the sun and increase the risk of sunburn. Patients are advised to use sunscreen, wear protective clothing, and limit sun exposure during treatment and for one week following discontinuation.

Drug Information (PDF)

This file contains official product information for Neutrogena Evenly Clear Acne Exfoliant, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Neutrogena Evenly Clear Acne Exfoliant, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.