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Nitrogen

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Active ingredient
Nitrogen 99 L/100 L
Other brand names
Dosage form
Gas
Route
Respiratory (inhalation)
Prescription status
Rx (prescription)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2009
Label revision date
October 21, 2024
FDA Insert
Prescribing information, PDF file
Active ingredient
Nitrogen 99 L/100 L
Other brand names
Dosage form
Gas
Route
Respiratory (inhalation)
Prescription status
Rx (prescription)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2009
Label revision date
October 21, 2024
Manufacturer
Gilmore Liquid Air Co.
Registration number
NDA205850
NDC root
51012-002
FDA Insert
Prescribing information, PDF file
Packaging Info (5 NDCs)
Packaging & NDC Codes (5)

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Drug Overview

Nitrogen, compressed NF (non-flammable gas), is a type of gas that is used in various applications, primarily in medical and industrial settings. It is important to note that the administration of nitrogen should only be performed by or under the supervision of a licensed practitioner who is experienced in its use.

This gas is stored under pressure and can be hazardous if not handled properly, as it may displace oxygen and lead to suffocation. Therefore, it is essential to follow safety precautions when using nitrogen, including ensuring proper ventilation and using appropriate equipment.

Uses

You may be considering the use of Nitrogen for specific medical purposes. It's important to know that the administration of Nitrogen can be hazardous and should only be done by a licensed practitioner who is experienced in its use. This professional will be familiar with the necessary indications, effects, dosages, methods, and the precautions that need to be taken.

Additionally, there are no reported teratogenic effects (which means it does not cause birth defects) or nonteratogenic effects associated with Nitrogen. Always consult with your healthcare provider to ensure safe and appropriate use.

Dosage and Administration

Using Nitrogen requires careful handling, as it can be hazardous or not suitable for everyone. It's important that this substance is administered only by a licensed healthcare professional who has experience with Nitrogen. This ensures that they are knowledgeable about its uses, effects, dosages, and the proper methods for administration.

Nitrogen is delivered through the respiratory system, which means you will inhale it. The healthcare provider will guide you on how often and for how long you should receive this treatment, ensuring that it is done safely and effectively. Always follow their instructions closely to ensure your safety and the best possible outcome.

What to Avoid

It’s important to be cautious when using Nitrogen. You should only use it under the supervision of a licensed practitioner who is experienced with its administration. This ensures that you are aware of the potential hazards and side effects associated with its use.

Additionally, make sure to follow these safety guidelines: do not handle Nitrogen until you have read and understood all safety precautions. Always use and store it outdoors or in a well-ventilated area. Lastly, avoid changing or forcing any connections, as this can lead to dangerous situations.

Side Effects

Using nitrogen can come with serious risks. It is important to be aware that nitrogen is a gas under pressure, which means it can explode if heated. Additionally, it can displace oxygen in the air, leading to rapid suffocation, so proper ventilation is crucial. If you come into contact with refrigerated nitrogen, it can cause cryogenic burns, which are severe injuries from extreme cold.

If you accidentally inhale nitrogen, move to fresh air immediately and seek medical help. For skin contact, gently thaw any frostbite with lukewarm water without rubbing the area, and get medical attention right away. Always prioritize safety when handling nitrogen.

Warnings and Precautions

Using Nitrogen can be risky, so it’s important to only use it under the guidance of a qualified healthcare professional who understands how to handle it safely. Be aware that Nitrogen is stored under pressure and can explode if heated. It can also displace oxygen, leading to rapid suffocation, and may cause cryogenic burns if it comes into contact with your skin.

To ensure your safety, always read and understand the safety precautions before handling Nitrogen. Use it outdoors or in a well-ventilated area, and wear protective gear like cold insulating gloves and a face shield. Make sure to keep the container upright, close the valve after each use, and follow the instructions in the Safety Data Sheet (SDS).

If you accidentally inhale Nitrogen, move to fresh air immediately and seek medical help. If it contacts your skin, gently thaw the affected area with lukewarm water—do not rub it—and get medical attention right away.

Overdose

If you suspect an overdose involving Nitrogen, it's important to act quickly. Signs of an overdose may include difficulty breathing or skin injuries from exposure. If someone has inhaled Nitrogen, immediately move them to fresh air and ensure they are comfortable while you seek medical advice or assistance.

If Nitrogen comes into contact with the skin, do not rub the affected area. Instead, gently thaw any frostbite with lukewarm water and seek immediate medical attention. Remember, Nitrogen can displace oxygen, leading to rapid suffocation, and it may also cause cryogenic burns due to its extremely cold temperature. Always prioritize safety and consult a healthcare professional if you have any concerns.

Pregnancy Use

Using Nitrogen during pregnancy may pose risks, and it is important to approach its use with caution. There are no specific guidelines or safety information available regarding its use in pregnant individuals, which means that the potential effects on you or your developing baby are not well understood.

If you are pregnant or planning to become pregnant, it is crucial to consult with a licensed healthcare provider who has experience in administering Nitrogen. They can provide guidance tailored to your situation and help ensure the safety of both you and your baby.

Lactation Use

If you are breastfeeding or planning to breastfeed, it's important to be aware that there is no specific information available regarding the use of this medication during nursing. This means that the effects on breast milk and your baby are not clearly understood.

As a precaution, you may want to discuss any medications you are considering with your healthcare provider to ensure they are safe for you and your nursing infant. Always prioritize your health and your baby's well-being when making decisions about medication while breastfeeding.

Pediatric Use

Using Nitrogen in children can be risky and is generally not recommended without careful consideration. If your child requires Nitrogen, it should only be administered by a licensed healthcare professional who has experience with this treatment, especially in children.

It's important to be aware of the potential dangers associated with Nitrogen use in kids, such as the risk of rapid suffocation and cryogenic burns (injuries caused by extremely cold substances). Always ensure that safety precautions are in place when this treatment is being considered for your child.

Geriatric Use

While there is no specific information available about the use of this medication in older adults, it's important to approach any new treatment with caution. If you or a loved one is an older adult, always consult with a healthcare provider before starting a new medication. They can help assess any potential risks and ensure that the treatment is safe and appropriate for your individual health needs.

Remember, older adults may have different responses to medications, so discussing any concerns or existing health conditions with your doctor is crucial for safe and effective care.

Renal Impairment

If you have kidney problems, it's important to know that there are no specific guidelines or dosage adjustments mentioned for your condition in the available information. This means that the usual recommendations for monitoring or safety considerations related to renal impairment (kidney issues) are not provided.

It's always best to consult with your healthcare provider about your individual situation, as they can offer personalized advice and ensure that any medications you take are safe and effective for you.

Hepatic Impairment

If you have liver problems, it's important to know that there are no specific guidelines or dosage adjustments mentioned for your condition in the available information. This means that the standard recommendations apply, but you should always consult your healthcare provider for personalized advice. They can help determine the best approach for your treatment and monitor your liver function as needed.

Make sure to keep your doctor informed about your liver health, as they may want to conduct regular tests to ensure your safety while using any medication. Your well-being is a priority, and your healthcare team is there to support you.

Drug Interactions

It's crucial to understand that the use of Nitrogen can be risky and should only be done under the guidance of a qualified healthcare professional who has experience with this substance. There are significant warnings associated with Nitrogen, including the potential for hazardous situations such as rapid suffocation due to oxygen displacement and the risk of explosion if heated. Additionally, because Nitrogen is a refrigerated gas, it can cause severe cold burns or injuries.

Before using Nitrogen or any related treatments, make sure to discuss your medical history and any other medications you are taking with your healthcare provider. This conversation is essential to ensure your safety and to avoid any dangerous interactions.

Storage and Handling

To ensure your safety and the proper use of the product, always store and use it outdoors or in a well-ventilated area. When temperatures rise above 52°C (125°F), make sure to protect the product from direct sunlight. After each use, close the valve and keep the container upright at all times. It's also important to use a backflow preventive device in the piping to avoid any potential hazards.

Before handling the product, read and understand all safety precautions. When you do handle it, be sure to wear cold insulating gloves, a face shield, and eye protection to safeguard against any risks. Avoid changing or forcing any connections, as this can lead to unsafe situations. Following these guidelines will help ensure your safety and the effective use of the product.

Additional Information

When using Nitrogen, it's important to be aware of safety precautions due to its potential hazards. Nitrogen is administered through inhalation and should only be used under the supervision of a licensed practitioner who is knowledgeable about its effects and risks. Always handle Nitrogen outdoors or in a well-ventilated area, and ensure you read and understand all safety guidelines before use.

Be cautious, as Nitrogen is stored under pressure and can explode if heated. It may also displace oxygen, leading to rapid suffocation. Always use protective equipment, such as cold insulating gloves and eye protection, and keep the container upright. If inhaled, move the person to fresh air and seek medical attention. If skin contact occurs, thaw the area with lukewarm water and get immediate medical help.

FAQ

What is Nitrogen, Compressed NF UN1066?

Nitrogen, Compressed NF UN1066 is a non-flammable gas used under the supervision of a licensed practitioner experienced in its administration.

What are the safety precautions for handling Nitrogen?

You must read and understand all safety precautions before handling Nitrogen. It should be used and stored outdoors or in a well-ventilated place.

What should I do if Nitrogen is inhaled?

If inhaled, remove the person to fresh air and keep them comfortable for breathing. Seek medical advice or attention immediately.

What are the risks associated with Nitrogen?

Nitrogen contains gas under pressure, which may explode if heated, and can displace oxygen, leading to rapid suffocation.

How should Nitrogen be stored?

Always store Nitrogen in an upright position, protect it from sunlight when temperatures exceed 52°C (125°F), and use a back flow preventive device in the piping.

Is there any information on the use of Nitrogen during pregnancy?

The provided information does not specify any safety concerns or precautions regarding the use of Nitrogen during pregnancy.

What should I do if Nitrogen comes into contact with skin?

If Nitrogen is on the skin, thaw frosted parts with lukewarm water without rubbing the area, and seek immediate medical advice or attention.

Who should administer Nitrogen?

Nitrogen should only be administered by or under the supervision of a licensed practitioner familiar with its indications, effects, and precautions.

Packaging Info

The table below lists all NDC Code configurations of Nitrogen, the U.S. brand-name prescription product. Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Nitrogen.
Details

FDA Insert (PDF)

This is the full prescribing document for Nitrogen, submitted to the U.S. Food and Drug Administration (FDA). It contains official information for healthcare providers, including how to use the medication, possible side effects, and safety warnings.

View FDA-approved insert (PDF)

Description

Nitrogen, compressed, is classified under NF UN1066 and is available by prescription only. It is a non-flammable gas, designated as a Class 2 gas. The chemical substance is identified by the CAS number 7727-37-9.

Uses and Indications

This drug is indicated for use in specific medical situations where the administration of Nitrogen is deemed necessary. It is essential that this drug be administered only by or under the supervision of a licensed practitioner who possesses experience in the use and administration of Nitrogen. The practitioner must be knowledgeable about the indications, effects, dosages, methods, frequency, and duration of administration, as well as the associated hazards, contraindications, side effects, and necessary precautions.

Limitations of use include the potential hazards associated with Nitrogen administration, which may render it contraindicated in certain circumstances. There are no reported teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

Administration of Nitrogen may pose hazards or contraindications. It is intended for use solely by or under the supervision of a licensed practitioner who possesses experience in the use and administration of Nitrogen. This practitioner should be well-versed in the indications, effects, dosages, methods, and frequency and duration of administration.

The route of administration for Nitrogen is via respiratory inhalation. It is essential that healthcare professionals adhere to established protocols and guidelines when administering this substance to ensure patient safety and efficacy.

Contraindications

Administration of Nitrogen is contraindicated in individuals who are not under the supervision of a licensed practitioner experienced in its use. The use of Nitrogen may pose hazards, and it is essential that practitioners are familiar with its indications, effects, dosages, methods, frequency, duration of administration, and associated risks.

Additionally, handling of Nitrogen should not occur until all safety precautions have been thoroughly read and understood. It is imperative to use and store Nitrogen exclusively outdoors or in a well-ventilated area. Connections should not be altered or forced, as this may lead to unsafe conditions.

Warnings and Precautions

Administration of Nitrogen may pose significant hazards and is contraindicated in certain situations. It is imperative that this substance is used solely by or under the supervision of a licensed practitioner who possesses experience in the use and administration of Nitrogen. The practitioner must be well-versed in the indications, effects, dosages, methods, frequency, duration of administration, as well as the associated hazards, contraindications, side effects, and necessary precautions.

Warnings

Nitrogen is classified as a gas under pressure, which presents a risk of explosion if subjected to heat. Additionally, it may displace oxygen in the environment, leading to rapid suffocation. The product also contains refrigerated gas, which can cause cryogenic burns or injuries. Users must be aware that exposure to this gas can similarly displace oxygen and result in rapid suffocation.

General Precautions

Prior to handling Nitrogen, it is essential that all safety precautions are thoroughly read and understood. The gas should only be used and stored outdoors or in a well-ventilated area to mitigate risks. Personal protective equipment, including cold insulating gloves, a face shield, and eye protection, must be worn at all times during handling. A backflow preventive device should be utilized in the piping to prevent any potential hazards.

Connections should never be changed or forced to fit, and the valve must be closed after each use and when the container is empty. It is critical to maintain the container in an upright position at all times. Users are advised to read and follow the Safety Data Sheet (SDS) before use to ensure comprehensive understanding of the associated risks and safety measures.

Emergency Medical Help Instructions

In the event of inhalation, it is crucial to remove the affected individual to fresh air and ensure they are comfortable for breathing. Medical advice or attention should be sought immediately.

Stop Taking and Call Your Doctor Instructions

If Nitrogen comes into contact with the skin, it is important to thaw any frostbitten areas with lukewarm water without rubbing the affected area. Immediate medical advice or attention should be obtained to address any potential injuries.

Side Effects

Administration of Nitrogen may pose significant risks to patients, as it is associated with several serious warnings. The gas is under pressure, which presents a risk of explosion if heated. Additionally, Nitrogen can displace oxygen, leading to rapid suffocation, a critical concern in enclosed or poorly ventilated spaces. The refrigerated nature of the gas also raises the potential for cryogenic burns or injuries, further emphasizing the need for caution during its use.

In the event of exposure, specific first aid measures should be taken. If Nitrogen is inhaled, it is crucial to remove the individual to fresh air and ensure they are comfortable for breathing. Medical advice or attention should be sought immediately. In cases where the gas comes into contact with the skin, it is important to thaw any frosted areas with lukewarm water without rubbing the affected skin. Immediate medical advice or attention is also recommended in these situations to prevent further injury.

These warnings and first aid recommendations highlight the importance of handling Nitrogen with care to mitigate the risks associated with its use.

Drug Interactions

Administration of Nitrogen is associated with significant safety warnings and contraindications. It is imperative that Nitrogen is used solely by or under the supervision of a licensed practitioner who possesses experience in its use and administration.

The administration of Nitrogen may pose hazards, including the potential for rapid suffocation due to oxygen displacement. Additionally, it is important to note that Nitrogen is classified as a gas under pressure, which presents risks of explosion if subjected to heat.

Furthermore, the refrigerated nature of Nitrogen can lead to cryogenic burns or injuries. Therefore, appropriate precautions must be taken to mitigate these risks during handling and administration.

Due to these safety concerns, careful monitoring and adherence to safety protocols are essential when using Nitrogen in any clinical setting.

Packaging & NDC

The table below lists all NDC Code configurations of Nitrogen, the U.S. brand-name prescription product. Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Nitrogen.
Details

Pediatric Use

Administration of Nitrogen in pediatric patients may pose significant risks and is contraindicated in certain situations. It is essential that Nitrogen is used only by or under the supervision of a licensed practitioner who has experience in its use and administration, particularly with pediatric considerations.

When administering Nitrogen to children, safety precautions must be strictly observed. Practitioners should be aware of potential hazards, including the risk of rapid suffocation and cryogenic burns, which can occur during administration. Careful monitoring and adherence to safety protocols are critical to ensure the well-being of pediatric patients.

Geriatric Use

Elderly patients may not have specific information regarding the use of this medication, including dosage adjustments, safety concerns, or special precautions. Therefore, healthcare providers should exercise caution when prescribing this medication to geriatric patients. It is advisable to monitor these patients closely for any potential adverse effects or changes in efficacy, given the lack of targeted data for this population.

Pregnancy

The administration of Nitrogen during pregnancy may pose potential risks, and its use is contraindicated or hazardous. There is no specific information available regarding the safety of Nitrogen in pregnant patients, including any known fetal impacts or outcomes. Due to the lack of data on its use during pregnancy, healthcare professionals are advised to exercise caution. Nitrogen should only be administered by or under the supervision of a licensed practitioner experienced in its use. Women of childbearing potential should be informed of the potential risks associated with Nitrogen administration during pregnancy, and appropriate precautions should be taken.

Lactation

There is no specific information available regarding the use of this medication in nursing mothers or its effects during lactation. Healthcare professionals should consider the lack of data when advising lactating mothers about the use of this medication. The potential risks and benefits should be carefully evaluated in the context of the individual patient's situation.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the available data regarding dosage adjustments, special monitoring, or safety considerations. Therefore, healthcare professionals should exercise caution when prescribing this medication to patients with reduced kidney function, as the lack of information necessitates careful clinical judgment and monitoring.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

In the event of overdosage, the administration of Nitrogen poses significant hazards and may be contraindicated. Healthcare professionals should be aware of the associated risks and take appropriate precautions.

Warnings

Nitrogen is classified as a gas under pressure, which presents a risk of explosion if subjected to heat. Additionally, it may displace oxygen in the environment, leading to rapid suffocation. The gas is also refrigerated, which can result in cryogenic burns or injuries upon contact with skin.

Symptoms

Exposure to Nitrogen can lead to symptoms associated with oxygen displacement, including dizziness, confusion, and loss of consciousness. Cryogenic burns may manifest as frostbite-like injuries on the skin.

First Aid Measures

In the case of inhalation, it is crucial to remove the affected individual to an area with fresh air and ensure they are comfortable while breathing. Medical advice or attention should be sought immediately.

For skin exposure, it is important to thaw any frosted areas using lukewarm water. Rubbing the affected area should be avoided to prevent further injury. Immediate medical advice or attention is also recommended in this scenario.

Healthcare professionals must remain vigilant and prepared to manage potential overdosage situations involving Nitrogen, ensuring that appropriate first aid measures are implemented promptly.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the use of the compound in question. Further studies may be necessary to elucidate these aspects of nonclinical toxicology.

Postmarketing Experience

Administration of Nitrogen has been associated with potential hazards, including contraindications. Reports indicate that the gas is under pressure, which may lead to explosive risks if heated. Additionally, it has been noted that Nitrogen can displace oxygen, posing a risk of rapid suffocation.

Furthermore, the presence of refrigerated gas in Nitrogen may result in cryogenic burns or injuries. The potential for oxygen displacement remains a significant concern, contributing to the risk of rapid suffocation in certain environments.

Patient Counseling

Healthcare providers should advise patients that the administration of Nitrogen may pose hazards or be contraindicated. It is essential that Nitrogen is used only by or under the supervision of a licensed practitioner who is experienced in its use and administration. This practitioner should be familiar with the indications, effects, dosages, methods, frequency and duration of administration, as well as the associated hazards, contraindications, side effects, and necessary precautions.

Patients should be made aware of the warning that Nitrogen contains gas under pressure, which may explode if heated, and that it can displace oxygen, leading to rapid suffocation. It is crucial to instruct patients not to handle Nitrogen until all safety precautions have been read and understood. Additionally, they should be informed that Nitrogen should only be used and stored outdoors or in a well-ventilated area.

Healthcare providers should emphasize the importance of using a back flow preventive device in the piping and ensuring that only equipment rated for cylinder pressure is utilized. Patients should be reminded to close the valve after each use and when the cylinder is empty. They should also be cautioned to protect the container from sunlight when the ambient temperature exceeds 52°C (125°F) and to read and follow the Safety Data Sheet (SDS) prior to use.

In the event of inhalation, patients should be instructed to remove themselves to fresh air and keep comfortable for breathing, while seeking medical advice or attention. Furthermore, it is important to inform patients that Nitrogen contains refrigerated gas, which may cause cryogenic burns or injury, and can also displace oxygen, leading to rapid suffocation. Patients should be advised to wear cold insulating gloves, a face shield, and eye protection when handling Nitrogen.

Healthcare providers should stress that connections should not be changed or forced, and that the container should always be kept in an upright position. In case of skin contact, patients should be instructed to thaw frosted areas with lukewarm water without rubbing the affected area and to seek immediate medical advice or attention.

Storage and Handling

The product is supplied in containers that must be used and stored exclusively outdoors or in a well-ventilated area. It is essential to protect the product from sunlight when the ambient temperature exceeds 52°C (125°F). After each use and when the container is empty, the valve should be closed to ensure safety.

Containers must always be maintained in an upright position to prevent leaks or spills. A backflow preventive device should be utilized in the piping to avoid contamination. Prior to handling the product, it is crucial that all safety precautions are thoroughly read and understood.

When handling the product, personnel are required to wear cold insulating gloves, a face shield, and eye protection to minimize the risk of injury. It is important to avoid changing or forcing connections, as this may compromise the integrity of the system.

Additional Clinical Information

The route of administration for the product is via respiratory inhalation. Clinicians should be aware that the administration of Nitrogen may pose hazards or be contraindicated, and it should only be used under the supervision of a licensed practitioner experienced in its use.

Patients must be informed of the potential risks associated with Nitrogen, including the presence of gas under pressure, which may explode if heated, and the risk of oxygen displacement leading to rapid suffocation. It is crucial to read and understand all safety precautions before handling. The product should be used and stored outdoors or in well-ventilated areas, and appropriate safety measures, such as using a backflow preventive device and protective equipment, should be followed. In case of inhalation, individuals should be moved to fresh air and kept comfortable for breathing, while immediate medical attention is advised for any adverse effects.

FDA Insert (PDF)

This document is the official FDA-approved prescribing information for Nitrogen as submitted by Gilmore Liquid Air Co.. It includes detailed information about indications, dosage, contraindications, warnings, and clinical pharmacology.

View full prescribing information (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Nitrogen, retrieved by a validated AI data-extraction workflow.

All FDA-approved dosage forms and strengths are listed in the Packaging & NDC Codes section above. Regulatory status, pharmacologic class (EPC), and mechanism of action (MoA) were cross-checked against the FDA Orange Book (NDA205850) and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.