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Nitrogen

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Active ingredient
Nitrogen 990 mL/1 L
Other brand names
Dosage form
Gas
Route
Respiratory (inhalation)
Prescription status
Rx (prescription)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2010
Label revision date
October 9, 2025
FDA Insert
Prescribing information, PDF file
Active ingredient
Nitrogen 990 mL/1 L
Other brand names
Dosage form
Gas
Route
Respiratory (inhalation)
Prescription status
Rx (prescription)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2010
Label revision date
October 9, 2025
Manufacturer
United States Cylinder Gas Corporation
Registration number
NDA205850
NDC root
68877-003
FDA Insert
Prescribing information, PDF file
Packaging Info (8 NDCs)
Packaging & NDC Codes (8)

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

Nitrogen, compressed NF UN1066, is a non-flammable gas commonly used in various industrial and medical applications. It is important to note that nitrogen is typically administered under the supervision of a licensed practitioner who is experienced in its use. This gas is often utilized for its ability to displace oxygen, which can be beneficial in certain controlled environments.

Due to its properties, nitrogen must be handled with care, as it is stored under pressure and can pose hazards if not managed properly. It is essential to follow safety precautions when using nitrogen to ensure a safe and effective experience.

Uses

You should know that the administration of Nitrogen can be risky and is not suitable for everyone. It is important that this treatment is only given by a licensed healthcare professional who has experience with Nitrogen. They will understand how to use it safely, including the correct dosages, methods, and how often it should be administered, as well as being aware of any potential hazards or side effects.

There are no specific teratogenic effects (which means it does not cause birth defects) or nonteratogenic effects noted with Nitrogen. However, always consult with your healthcare provider for personalized advice and to ensure that this treatment is appropriate for your situation.

Dosage and Administration

It's important to know that this medication should only be used by you or under the supervision of a licensed healthcare professional who has experience with Nitrogen. This ensures that you receive the safest and most effective care.

You will be using this medication through your respiratory system, which means you will inhale it. The active ingredient in this medication is Nitrogen, and it comes in a container that holds 990 mL of Nitrogen in a total volume of 1 liter. Make sure to follow your healthcare provider's instructions on how often to use it, as they will guide you based on your specific needs.

What to Avoid

It's important to follow specific guidelines when using this medication to ensure your safety. First, make sure to read and understand all safety precautions before handling the product. Avoid changing or forcing any connections, as this could lead to complications. If the medication comes into contact with your skin, do not rub the affected area, as this may worsen any irritation.

By adhering to these instructions, you can help prevent any potential issues and ensure a safer experience with the medication. Always prioritize your safety and well-being.

Side Effects

Using this product comes with important safety considerations. It contains refrigerated gas, which can lead to cryogenic burns (injuries caused by extreme cold) or other injuries. Additionally, the gas may displace oxygen in the air, potentially leading to rapid suffocation.

If you or someone else inhales the gas, it's crucial to move to fresh air and stay comfortable while breathing. If the gas comes into contact with the skin, gently thaw any frostbite with lukewarm water without rubbing the area, and seek immediate medical advice.

Warnings and Precautions

Using Nitrogen can be risky, so it’s important to only use it under the guidance of a qualified healthcare professional who understands how to handle it safely. Be aware that Nitrogen is stored under pressure and can explode if heated. It can also displace oxygen, leading to rapid suffocation, and may cause cryogenic burns if it comes into contact with your skin.

To ensure your safety, always read and understand the safety precautions before handling Nitrogen. Use it outdoors or in a well-ventilated area, and make sure to wear protective gear like cold insulating gloves and eye protection. Keep the container upright, close the valve after use, and protect it from sunlight in high temperatures.

If you inhale Nitrogen, move to fresh air immediately and seek medical help. If it contacts your skin, gently thaw the area with lukewarm water—do not rub it—and get medical attention right away.

Overdose

It appears that there is no specific information available regarding overdosage for this medication. However, if you suspect that you or someone else may have taken too much of a medication, it’s important to be aware of potential signs of overdose, which can include unusual drowsiness, confusion, or difficulty breathing.

If you notice any of these symptoms, or if you are unsure whether an overdose has occurred, seek immediate medical help. You can contact your local emergency services or go to the nearest hospital. Always keep medications out of reach and follow the prescribed dosage to prevent any risks associated with overdosage.

Pregnancy Use

Using Nitrogen during pregnancy can be risky, and it is important to approach its use with caution. You should only use Nitrogen under the guidance of a licensed healthcare professional who has experience with this substance. This expert will be knowledgeable about the appropriate dosages, methods of administration, and potential side effects, as well as the specific precautions necessary to ensure your safety and that of your developing baby.

If you are pregnant or planning to become pregnant, it is crucial to discuss any potential use of Nitrogen with your healthcare provider to understand the risks and ensure that you are making informed decisions about your health and the health of your baby.

Lactation Use

If you are breastfeeding or planning to breastfeed, it's important to know that there is no specific information available regarding the use of this medication during nursing. This means that the effects on breast milk and your nursing infant are not clearly defined.

As always, it's best to consult with your healthcare provider about any medications you are considering while breastfeeding. They can help you weigh the potential risks and benefits to ensure the safety of both you and your baby.

Pediatric Use

Using Nitrogen for children should be approached with caution. It is important to know that Nitrogen can be hazardous and should only be administered by a licensed healthcare professional who is experienced in its use. This professional will understand the necessary dosages, methods, and potential risks involved.

You should also be aware that Nitrogen is stored under pressure and can explode if heated. It may displace oxygen, leading to rapid suffocation, and can cause cryogenic burns if it comes into contact with skin. Always use and store Nitrogen outdoors or in a well-ventilated area. If inhaled, move the child to fresh air and seek medical attention. If there is skin contact, gently thaw any frostbite with lukewarm water and seek immediate medical help.

Geriatric Use

While there is no specific information available about the use of this medication in older adults, it’s important to approach any new treatment with caution. Since older adults may have different health needs and responses to medications, you should always consult with a healthcare provider before starting any new medication. They can help determine the right dosage and monitor for any potential side effects, ensuring that the treatment is safe and effective for you or your loved one.

Renal Impairment

If you have kidney problems, it's important to know that there are no specific guidelines or dosage adjustments mentioned for your condition in the available information. This means that the usual safety considerations and monitoring practices for patients with renal impairment (kidney issues) are not detailed.

It's always best to consult your healthcare provider for personalized advice and to ensure that any medications you take are safe and appropriate for your kidney health. They can provide guidance tailored to your specific situation.

Hepatic Impairment

If you have liver problems, it's important to know that there are no specific guidelines or dosage adjustments mentioned for your condition in the available information. This means that the standard recommendations apply, but you should always consult your healthcare provider for personalized advice. They can help determine the best approach for your treatment and monitor your liver function as needed.

Make sure to keep your doctor informed about your liver health, as they may want to conduct regular tests to ensure your safety while using any medication. Your well-being is a priority, so don't hesitate to ask questions or express any concerns you may have.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you.

Always discuss your full list of medications, including over-the-counter drugs and supplements, as well as any upcoming lab tests. This way, you can avoid any potential issues and receive the best care possible.

Storage and Handling

To ensure your safety and the proper use of the product, always store and use it outdoors or in a well-ventilated area. When temperatures rise above 52 degrees Celsius (125 degrees Fahrenheit), make sure to protect the product from direct sunlight. After each use, close the valve and keep the container upright at all times.

When handling the product, it’s important to wear cold insulating gloves, a face shield, and eye protection to safeguard against any potential hazards. Additionally, use a backflow preventive device in the piping to avoid any unwanted backflow. Before you begin, please read and understand all safety precautions, including the Safety Data Sheet (SDS), to ensure safe handling and usage.

Additional Information

You will use this medication through inhalation, which means you will breathe it in to receive the treatment. There are no additional details available regarding laboratory tests, abuse potential, or patient counseling information.

FAQ

What is Nitrogen, compressed NF UN1066?

Nitrogen, compressed NF UN1066 is a non-flammable gas used under the supervision of a licensed practitioner experienced in its administration.

What are the safety precautions for handling Nitrogen?

You must read and understand all safety precautions before handling Nitrogen, as it contains gas under pressure and may explode if heated.

What should I do if Nitrogen is inhaled?

If inhaled, remove the person to fresh air and keep them comfortable for breathing. Seek medical advice or attention immediately.

How should Nitrogen be stored?

Store Nitrogen only outdoors or in a well-ventilated place, and protect it from sunlight when the ambient temperature exceeds 52 degrees C (125 degrees F).

What is the route of administration for Nitrogen?

Nitrogen is administered via respiratory inhalation.

What should I do if Nitrogen comes into contact with skin?

Thaw frosted parts with lukewarm water and do not rub the affected area. Get immediate medical advice or attention.

Who should administer Nitrogen?

Nitrogen should only be administered by or under the supervision of a licensed practitioner familiar with its indications, effects, and precautions.

What are the potential hazards of using Nitrogen?

Nitrogen may displace oxygen and cause rapid suffocation, and it can cause cryogenic burns or injury.

Packaging Info

The table below lists all NDC Code configurations of Nitrogen, the U.S. brand-name prescription product. Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Nitrogen.
Details

FDA Insert (PDF)

This is the full prescribing document for Nitrogen, submitted to the U.S. Food and Drug Administration (FDA). It contains official information for healthcare providers, including how to use the medication, possible side effects, and safety warnings.

View FDA-approved insert (PDF)

Description

No description information is available for the specified drug.

Uses and Indications

This drug is indicated for use in specific medical situations where the administration of Nitrogen is deemed necessary. It is essential that this drug be administered only by or under the supervision of a licensed practitioner who possesses experience in the use and administration of Nitrogen. The practitioner must be knowledgeable about the indications, effects, dosages, methods, frequency, and duration of administration, as well as the associated hazards, contraindications, side effects, and necessary precautions.

Limitations of use include the potential hazards associated with Nitrogen administration, which may render it contraindicated in certain circumstances. There are no specific teratogenic or nonteratogenic effects reported for this drug.

Dosage and Administration

For administration, Nitrogen is intended for use only by or under the supervision of a licensed practitioner experienced in its use and administration.

The route of administration is via respiratory inhalation. The active ingredient is Nitrogen, provided in a concentration of 990 mL within a 1 L container.

Healthcare professionals should ensure that the administration is conducted in a controlled environment, adhering to established safety protocols. The specific dosage and frequency of administration should be determined based on the clinical context and patient needs, as guided by the supervising practitioner.

Contraindications

Use of this product is contraindicated in the following situations:

Handling of the product should not occur until all safety precautions have been thoroughly read and understood. Additionally, connections should not be changed or forced, as this may lead to improper use or safety hazards. In the event of skin contact, do not rub the affected area to avoid exacerbating any potential irritation.

Warnings and Precautions

Administration of Nitrogen may pose significant hazards and is contraindicated in certain situations. It is imperative that this substance is used solely by or under the supervision of a licensed practitioner who possesses experience in the use and administration of Nitrogen. This practitioner must be well-versed in the indications, effects, dosages, methods, frequency, duration of administration, as well as the associated hazards, contraindications, side effects, and necessary precautions.

Warnings

Nitrogen is classified as a gas under pressure, which presents a risk of explosion if subjected to heat. Additionally, it may displace oxygen in the environment, leading to rapid suffocation. The product also contains refrigerated gas, which can cause cryogenic burns or injuries. Users must be aware that exposure to Nitrogen can result in a hazardous environment due to oxygen displacement.

General Precautions

Prior to handling Nitrogen, it is essential that all safety precautions are thoroughly read and understood. The substance should only be used and stored outdoors or in a well-ventilated area to mitigate risks. A backflow preventive device must be utilized in the piping to ensure safety. Equipment used must be rated for cylinder pressure, and the valve should be closed after each use and when the cylinder is empty.

Containers should be protected from sunlight, particularly when ambient temperatures exceed 52 degrees Celsius (125 degrees Fahrenheit). Personal protective equipment, including cold insulating gloves, a face shield, and eye protection, is strongly recommended. Connections should not be changed or forced, and containers must always be kept in an upright position. It is crucial to read and follow the Safety Data Sheet (SDS) before use to ensure comprehensive understanding of the associated risks.

Emergency Medical Help Instructions

In the event of inhalation, the affected individual should be removed to fresh air and kept comfortable for breathing. Immediate medical advice or attention should be sought. If Nitrogen comes into contact with the skin, it is important to thaw any frosted areas with lukewarm water without rubbing the affected area. Prompt medical advice or attention is also necessary in this case.

No specific laboratory tests are recommended for monitoring the use of Nitrogen. However, practitioners should remain vigilant and prepared to respond to any adverse effects or emergencies that may arise during administration.

Side Effects

Patients should be aware that the product contains refrigerated gas, which may lead to cryogenic burns or injury. Additionally, the gas has the potential to displace oxygen, resulting in rapid suffocation.

In the event of exposure, immediate first aid measures are recommended. If the gas is inhaled, the affected individual should be removed to fresh air and kept comfortable for breathing. In cases where the gas comes into contact with the skin, it is advised to thaw any frosted areas with lukewarm water without rubbing the affected skin. Immediate medical advice or attention should be sought in both scenarios to ensure proper care and management of any adverse effects.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there is no information available regarding interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

The table below lists all NDC Code configurations of Nitrogen, the U.S. brand-name prescription product. Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Nitrogen.
Details

Pediatric Use

Administration of Nitrogen in pediatric patients may pose significant hazards and is contraindicated in certain situations. It is essential that Nitrogen is used only by or under the supervision of a licensed practitioner experienced in its administration, who is knowledgeable about the indications, effects, dosages, methods, frequency, duration of administration, and associated hazards, contraindications, side effects, and necessary precautions.

Healthcare professionals should be aware of the following warnings: Nitrogen is a gas under pressure and may explode if heated. It can displace oxygen, leading to rapid suffocation, and contains refrigerated gas that may cause cryogenic burns or injury. Therefore, it is crucial to use and store Nitrogen only outdoors or in well-ventilated areas.

In the event of inhalation, the affected individual should be removed to fresh air and kept comfortable for breathing, with medical advice or attention sought immediately. If Nitrogen comes into contact with the skin, thaw any frosted areas with lukewarm water without rubbing the affected area, and seek immediate medical advice or attention.

Geriatric Use

There is no specific information available regarding the use of this medication in geriatric patients, including dosage adjustments, safety concerns, or special precautions. Healthcare providers should exercise caution when prescribing this medication to elderly patients, as individual responses may vary. Monitoring for potential adverse effects and therapeutic efficacy is recommended in this population.

Pregnancy

The administration of Nitrogen during pregnancy may pose potential risks and is considered hazardous or contraindicated. Pregnant patients should only receive Nitrogen under the supervision of a licensed practitioner who is experienced in its use and administration. This practitioner must be knowledgeable about the indications, effects, dosages, methods, frequency, duration of administration, as well as the associated hazards, contraindications, side effects, and necessary precautions.

Due to the lack of comprehensive data on the effects of Nitrogen on fetal outcomes, healthcare professionals are advised to carefully weigh the potential benefits against the risks when considering its use in pregnant patients. It is essential to ensure that any administration is conducted with the utmost caution and under appropriate medical supervision.

Lactation

There is no specific information available regarding the use of this medication in nursing mothers or its effects during lactation. Consequently, healthcare professionals should exercise caution when considering this medication for lactating mothers. The potential risks and benefits should be carefully evaluated, and alternative treatments may be considered if necessary. Breastfed infants may be affected by medications taken by their nursing mothers; therefore, monitoring for any adverse effects is advisable.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the available prescribing information. There are no dosage adjustments, special monitoring requirements, or safety considerations outlined for individuals with reduced kidney function. Healthcare professionals should exercise caution and consider the lack of data when prescribing to this patient population.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

In the absence of specific overdosage information, it is essential for healthcare professionals to remain vigilant regarding the potential for overdose with this medication. In cases where an overdose is suspected, immediate medical attention should be sought.

Healthcare providers are advised to monitor patients closely for any signs or symptoms that may indicate an overdose. These may include, but are not limited to, increased severity of known side effects, altered mental status, or any unusual physiological responses.

Management of an overdose should be guided by the clinical presentation of the patient. Supportive care is paramount, and symptomatic treatment should be initiated as necessary. Healthcare professionals should also consider contacting a poison control center for additional guidance on the management of overdose cases.

In summary, while specific overdosage information is not available, healthcare professionals should exercise caution, monitor for symptoms, and provide appropriate supportive care in the event of an overdose.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the compound in these areas.

Postmarketing Experience

No postmarketing experience details are available in the provided text.

Patient Counseling

Healthcare providers should advise patients that the administration of Nitrogen may pose hazards or be contraindicated. It is essential that Nitrogen is used only by or under the supervision of a licensed practitioner who is experienced in its use and administration. This practitioner should be familiar with the indications, effects, dosages, methods, frequency and duration of administration, as well as the associated hazards, contraindications, side effects, and necessary precautions.

Patients should be made aware of the warning that Nitrogen contains gas under pressure, which may explode if heated. Additionally, it may displace oxygen and cause rapid suffocation. Therefore, healthcare providers must emphasize the importance of not handling Nitrogen until all safety precautions have been read and understood. Patients should be instructed to use and store Nitrogen only outdoors or in a well-ventilated area.

It is crucial to use a backflow preventive device in the piping and to utilize equipment rated for cylinder pressure. Patients should be reminded to close the valve after each use and when the cylinder is empty. They should also protect the Nitrogen container from sunlight when the ambient temperature exceeds 52 degrees Celsius (125 degrees Fahrenheit) and to read and follow the Safety Data Sheet (SDS) prior to use.

In the event of inhalation, patients should be instructed to remove themselves to fresh air and keep comfortable for breathing, while seeking medical advice or attention. Providers should also warn patients that Nitrogen contains refrigerated gas, which may cause cryogenic burns or injury. Patients should wear cold insulating gloves, a face shield, and eye protection when handling Nitrogen.

Healthcare providers must caution patients against changing or forcing connections and advise them to always keep the container in an upright position. In case of skin contact, patients should thaw frosted areas with lukewarm water without rubbing the affected area and seek immediate medical advice or attention.

Storage and Handling

The product is supplied in a manner that necessitates careful handling and storage to ensure safety and efficacy. It must be used and stored exclusively outdoors or in a well-ventilated area. To maintain product integrity, it is essential to protect it from sunlight when the ambient temperature exceeds 52 degrees Celsius (125 degrees Fahrenheit).

After each use and when the container is empty, the valve should be securely closed. The container must always be kept in an upright position to prevent leaks or spills. When handling the product, personnel are required to wear cold insulating gloves, a face shield, and eye protection to mitigate any risk of exposure.

Additionally, a backflow preventive device should be utilized in the piping to ensure safe operation. It is imperative that all safety precautions are thoroughly read and understood before handling the product. Users should consult and adhere to the Safety Data Sheet (SDS) prior to use to ensure compliance with safety protocols.

Additional Clinical Information

The route of administration for the medication is via respiratory inhalation. There are no additional details available regarding laboratory tests, abuse information, patient counseling, or postmarketing experience.

FDA Insert (PDF)

This document is the official FDA-approved prescribing information for Nitrogen as submitted by United States Cylinder Gas Corporation. It includes detailed information about indications, dosage, contraindications, warnings, and clinical pharmacology.

View full prescribing information (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Nitrogen, retrieved by a validated AI data-extraction workflow.

All FDA-approved dosage forms and strengths are listed in the Packaging & NDC Codes section above. Regulatory status, pharmacologic class (EPC), and mechanism of action (MoA) were cross-checked against the FDA Orange Book (NDA205850) and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.