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Nitrogen

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Active ingredient
Nitrogen 990 mL/1 L
Other brand names
Dosage form
Gas
Route
Respiratory (inhalation)
Prescription status
Rx (prescription)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 1973
Label revision date
January 6, 2026
FDA Insert
Prescribing information, PDF file
Active ingredient
Nitrogen 990 mL/1 L
Other brand names
Dosage form
Gas
Route
Respiratory (inhalation)
Prescription status
Rx (prescription)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 1973
Label revision date
January 6, 2026
Manufacturer
Welders Supply Company
Registration number
NDA205766
NDC root
11999-002
FDA Insert
Prescribing information, PDF file
Packaging Info (2 NDCs)
Packaging & NDC Codes (2)

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

Nitrogen, Refrigerated Liquid NF UN1977 is a non-flammable gas that is stored in a refrigerated liquid form. It is primarily used in various industrial applications, particularly in processes that require a cryogenic environment. Due to its properties, nitrogen can displace oxygen, which is why it is important to handle it with care and under the supervision of a qualified practitioner.

When using nitrogen, safety precautions are essential to prevent hazards such as cryogenic burns or suffocation. It is crucial to understand the proper handling and storage guidelines to ensure a safe working environment.

Uses

You may be prescribed Nitrogen for specific medical uses, but it's important to know that its administration can be risky. This treatment should only be given by a licensed healthcare professional who has experience with Nitrogen. They will understand how to use it safely, including the correct dosages and methods, as well as being aware of any potential hazards or side effects.

Interestingly, there are no reported teratogenic effects (which means it doesn't cause birth defects) or nonteratogenic effects associated with Nitrogen. However, always consult your healthcare provider for personalized advice and information regarding your treatment.

Dosage and Administration

Using Nitrogen requires careful handling and should only be done by a licensed practitioner who has experience with this substance. It’s important to understand that administering Nitrogen can be hazardous or not recommended in certain situations, so professional supervision is essential.

When using Nitrogen, it is delivered through the respiratory system, which means you will inhale it. The active ingredient in this preparation is Nitrogen, with a concentration of 990 mL in a total volume of 1 liter. Always follow your healthcare provider's instructions regarding how and when to use this medication to ensure your safety and effectiveness.

What to Avoid

It's important to follow specific guidelines to ensure your safety when using this product. First, make sure to read and understand all safety precautions before handling it. Always use and store the product outdoors or in a well-ventilated area to minimize any potential risks. Additionally, avoid changing or forcing any connections, as this could lead to unsafe situations.

By adhering to these instructions, you can help ensure a safer experience with the product. If you have any questions or concerns, don't hesitate to reach out for more information.

Side Effects

Using this product comes with important safety considerations. It contains refrigerated gas, which can lead to cryogenic burns (injuries caused by extreme cold) or other injuries. Additionally, the gas may displace oxygen in the air, potentially leading to rapid suffocation.

If you or someone else inhales the gas, it's crucial to move to fresh air immediately and stay comfortable while breathing. If the gas comes into contact with the skin, gently thaw any frostbite with lukewarm water—avoid rubbing the area—and seek medical advice right away.

Warnings and Precautions

Using Nitrogen can be risky and should only be done by a licensed professional who knows how to handle it safely. This gas can cause serious injuries, such as cryogenic burns (frostbite from extremely cold substances) and can displace oxygen, leading to suffocation. Always read and understand the safety precautions before handling Nitrogen. Make sure to use it outdoors or in a well-ventilated area, wear protective gear like cold insulating gloves and a face shield, and keep the container upright.

If someone inhales Nitrogen, move them to fresh air and ensure they are comfortable while breathing. If Nitrogen comes into contact with the skin, gently thaw the affected area with lukewarm water—do not rub it—and seek immediate medical attention. Always close the valve after use and when the container is empty, and follow the Safety Data Sheet (SDS) for detailed safety information.

Overdose

It appears that there is no specific information available regarding overdosage for this medication. However, it’s always important to be aware of the signs of an overdose, which can include unusual symptoms or worsening of your condition. If you suspect that you or someone else may have taken too much of a medication, it’s crucial to seek immediate medical help.

In case of an overdose, contact your healthcare provider or local emergency services right away. They can provide guidance on what steps to take next. Always keep medications out of reach and follow the prescribed dosage to minimize the risk of an overdose.

Pregnancy Use

It is important to know that Nitrogen is not safe to use during pregnancy. The administration of Nitrogen can pose risks to your developing fetus, and there are no established safety guidelines for its use in pregnant individuals. If you are pregnant or planning to become pregnant, it is crucial to avoid Nitrogen and discuss any concerns with your healthcare provider to ensure the health and safety of both you and your baby.

Lactation Use

Currently, there is no specific information available about the use of Nitrogen for nursing mothers or its effects on breastfeeding. This means that if you are breastfeeding or planning to breastfeed, it’s important to consult with your healthcare provider for personalized advice. They can help you understand any potential risks and make informed decisions regarding your health and your baby's well-being. Always prioritize open communication with your doctor about any medications you may be considering while breastfeeding.

Pediatric Use

Currently, there is no specific information available regarding the use of Nitrogen in children. This means that if you are considering this treatment for a child, it is important to consult with a healthcare professional for guidance. They can provide you with the best advice tailored to your child's needs and ensure their safety. Always prioritize professional medical advice when it comes to medications for young ones.

Geriatric Use

While there is no specific information available about the use of this medication in older adults, it’s important to approach any new treatment with caution. Since older adults may have different health needs and responses to medications, you should always consult with a healthcare provider before starting any new medication. They can help determine the right dosage and monitor for any potential side effects, ensuring that the treatment is safe and effective for you or your loved one.

Renal Impairment

If you have kidney problems, it's important to know that the information provided does not include specific guidelines for dosage adjustments, special monitoring, or safety considerations related to renal impairment (kidney issues). This means that there are no tailored recommendations for how your treatment may need to change based on your kidney function.

Always consult your healthcare provider for personalized advice and to ensure that your treatment is safe and effective, especially if you have any concerns about your kidney health.

Hepatic Impairment

If you have liver problems, it's important to know that there are no specific guidelines, dosage adjustments, or special monitoring instructions provided for your condition in the available information. This means that the medication may not have been studied in depth for its effects on individuals with liver impairment.

Always consult your healthcare provider for personalized advice and to discuss any concerns you may have regarding your liver health and medication use. They can help ensure that your treatment is safe and effective based on your individual health needs.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you. Always share your complete list of medications and any recent lab tests to avoid any potential issues. Your health and safety should always come first.

Storage and Handling

To ensure your safety and the proper use of the product, always store it outdoors or in a well-ventilated area. Keep the container upright at all times to prevent leaks or spills. After each use, make sure to close the valve, especially when the container is empty, to avoid any accidental release of contents.

When handling the product, it's important to wear protective gear, including cold insulating gloves, a face shield, and eye protection. Before you begin, take a moment to read the Safety Data Sheet (SDS), which provides essential information about the product's hazards and safe handling practices. Following these guidelines will help you use the product safely and effectively.

Additional Information

You will use this medication through inhalation, which means you will breathe it in to receive the treatment. There are no additional details available regarding laboratory tests, abuse potential, patient counseling, or postmarketing experiences related to this medication.

FAQ

What is Nitrogen, Refrigerated Liquid NF UN1977?

Nitrogen, Refrigerated Liquid NF UN1977 is a non-flammable gas that is stored as a refrigerated liquid.

Who should administer Nitrogen?

Nitrogen should only be administered by or under the supervision of a licensed practitioner experienced in its use and administration.

What are the safety precautions for handling Nitrogen?

You must read and understand all safety precautions before handling Nitrogen. It should be used and stored outdoors or in a well-ventilated area, and protective equipment like cold insulating gloves and a face shield should be worn.

What should I do if Nitrogen is inhaled?

If inhaled, remove the person to fresh air and keep them comfortable for breathing. Seek immediate medical advice if necessary.

Can Nitrogen cause any injuries?

Yes, Nitrogen can cause cryogenic burns or injury and may displace oxygen, leading to rapid suffocation.

Is Nitrogen safe to use during pregnancy?

Nitrogen is contraindicated in pregnancy and may pose risks to the fetus; safety concerns regarding its use during pregnancy have not been established.

What should I do if Nitrogen comes into contact with skin?

If Nitrogen contacts the skin, thaw the frosted parts with lukewarm water and seek immediate medical attention. Do not rub the affected area.

What is the route of administration for Nitrogen?

The route of administration for Nitrogen is respiratory (inhalation).

What should I do after using Nitrogen?

Close the valve after each use and when the container is empty, and always keep the container in an upright position.

Packaging Info

The table below lists all NDC Code configurations of Nitrogen, the U.S. brand-name prescription product. Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Nitrogen.
Details

FDA Insert (PDF)

This is the full prescribing document for Nitrogen, submitted to the U.S. Food and Drug Administration (FDA). It contains official information for healthcare providers, including how to use the medication, possible side effects, and safety warnings.

View FDA-approved insert (PDF)

Description

No description information is available for the drug.

Uses and Indications

This drug is indicated for use in specific medical situations where the administration of Nitrogen is deemed necessary. It is essential that this drug be administered only by or under the supervision of a licensed practitioner who possesses experience in the use and administration of Nitrogen. The practitioner must be knowledgeable about the indications, effects, dosages, methods, frequency, and duration of administration, as well as the associated hazards, contraindications, side effects, and necessary precautions.

Limitations of use include the potential hazards associated with Nitrogen administration, which may render it contraindicated in certain circumstances. There are no reported teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

Administration of Nitrogen should only be conducted by or under the supervision of a licensed practitioner experienced in its use and administration, as it may pose hazards or contraindications.

The recommended route of administration is via respiratory inhalation. The active ingredient is Nitrogen, provided in a concentration of 990 mL within a 1 L container.

Healthcare professionals must ensure that appropriate safety measures are in place during administration to mitigate any potential risks associated with the use of Nitrogen.

Contraindications

Use of this product is contraindicated in situations where safety precautions have not been read and understood. Additionally, it should only be used and stored outdoors or in a well-ventilated area to minimize risks associated with inadequate ventilation. Furthermore, any attempts to change or force fit connections are contraindicated, as this may compromise safety and functionality.

Warnings and Precautions

Administration of Nitrogen may pose significant risks and is contraindicated in certain situations. It is imperative that this substance is used solely by or under the supervision of a licensed practitioner who possesses experience in the use and administration of Nitrogen. The practitioner must be well-versed in the indications, effects, dosages, methods, frequency, duration of administration, as well as the associated hazards, contraindications, side effects, and necessary precautions.

Hazards Associated with Nitrogen Use

Nitrogen is classified as a refrigerated gas, which presents specific dangers. It may cause cryogenic burns or injuries upon contact. Additionally, Nitrogen can displace oxygen in the environment, leading to rapid suffocation. Therefore, it is crucial to adhere to all safety precautions prior to handling this substance. Users must ensure that they read and fully understand all safety guidelines. Nitrogen should only be used and stored outdoors or in well-ventilated areas.

When handling Nitrogen, appropriate personal protective equipment (PPE) is essential. This includes wearing cold insulating gloves, a face shield, and eye protection. A backflow preventive device should be utilized in the piping to mitigate risks. It is critical to avoid changing or forcing connections and to close the valve after each use and when the container is empty. The container must always be maintained in an upright position. Prior to use, individuals should read and follow the Safety Data Sheet (SDS) for comprehensive safety information.

Emergency Procedures

In the event of an emergency, immediate action is required. If Nitrogen is inhaled, the affected individual should be removed to fresh air and kept comfortable for breathing. If there is skin contact, any frostbite should be treated by thawing the affected areas with lukewarm water; rubbing the area is contraindicated. Prompt medical advice and attention should be sought in all cases of exposure.

Side Effects

Patients should be aware of the potential for serious adverse reactions associated with the use of this product. The product contains refrigerated gas, which may lead to cryogenic burns or injury upon contact with skin or mucous membranes. Inhalation of the gas can displace oxygen, resulting in rapid suffocation.

In the event of exposure, immediate first aid measures are crucial. If inhaled, it is recommended to remove the individual to fresh air and ensure they are comfortable for breathing. For skin exposure, it is advised to thaw any frosted areas with lukewarm water, taking care not to rub the affected area. Prompt medical advice and attention should be sought in all cases of exposure to mitigate potential harm.

These warnings highlight the importance of handling the product with care to prevent serious injuries and ensure patient safety.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there is no information available regarding interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

The table below lists all NDC Code configurations of Nitrogen, the U.S. brand-name prescription product. Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Nitrogen.
Details

Pediatric Use

No pediatric use information is provided in the drug insert for Nitrogen. Therefore, the safety and efficacy of this drug in pediatric patients have not been established. Healthcare professionals should exercise caution when considering the use of Nitrogen in children, infants, or adolescents, as there are no available data to guide dosing or treatment outcomes in these populations.

Geriatric Use

Elderly patients may not have specific information regarding the use of this medication, including dosage adjustments, safety concerns, or special precautions. Therefore, healthcare providers should exercise caution when prescribing this medication to geriatric patients. It is advisable to monitor these patients closely for any adverse effects or changes in therapeutic response, given the lack of targeted data for this population.

Pregnancy

The use of Nitrogen is contraindicated in pregnancy due to potential risks to the fetus. Administration of Nitrogen during this period may pose significant risks, and safety concerns regarding its use in pregnant patients have not been established. Healthcare professionals should exercise caution and consider alternative therapies when treating women of childbearing potential who are pregnant or may become pregnant.

Lactation

There are no specific statements or information regarding nursing mothers or lactation in the provided drug insert for Nitrogen. Therefore, the effects on breastfed infants and the excretion of Nitrogen in breast milk remain undetermined. Healthcare professionals should consider this lack of data when advising lactating mothers on the use of this medication.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the prescribing information regarding dosage adjustments, special monitoring, or safety considerations. Therefore, healthcare professionals should exercise caution when prescribing this medication to patients with reduced kidney function, as the lack of data necessitates careful clinical judgment. Regular monitoring of renal function may be advisable in these patients, although specific recommendations are not provided.

Hepatic Impairment

There is no information available regarding the use of this medication in patients with hepatic impairment. Consequently, there are no dosage adjustments, special monitoring requirements, or precautions specified for individuals with compromised liver function. Healthcare professionals should exercise caution and consider the lack of data when prescribing this medication to patients with liver problems.

Overdosage

In the absence of specific overdosage information, it is essential for healthcare professionals to remain vigilant regarding the potential for overdose with this medication. In cases where an overdose is suspected, immediate medical attention should be sought.

Healthcare providers are advised to monitor patients closely for any signs or symptoms that may indicate an overdose. These may include, but are not limited to, increased severity of known side effects, altered mental status, or any unusual physiological responses.

Management of an overdose should be guided by the clinical presentation of the patient. Supportive care is paramount, and symptomatic treatment should be initiated as necessary. Healthcare professionals should also consider contacting a poison control center for additional guidance on the management of overdose cases.

In summary, while specific overdosage information is not available, healthcare professionals should exercise caution, monitor for symptoms, and provide appropriate supportive care in the event of an overdose.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the compound in these areas.

Postmarketing Experience

No postmarketing experience details are available in the insert text.

Patient Counseling

Healthcare providers should advise patients that the administration of Nitrogen may pose hazards or be contraindicated. It is essential that Nitrogen is used only by or under the supervision of a licensed practitioner who is experienced in its use and administration. This practitioner should be familiar with the indications, effects, dosages, methods, frequency and duration of administration, as well as the associated hazards, contraindications, side effects, and necessary precautions.

Patients should be made aware of the warning that Nitrogen contains refrigerated gas, which may cause cryogenic burns or injury. Additionally, it may displace oxygen and lead to rapid suffocation. Therefore, healthcare providers must emphasize the importance of understanding all safety precautions before handling Nitrogen.

Patients should be instructed to use and store Nitrogen only outdoors or in a well-ventilated area. It is crucial to wear appropriate protective gear, including cold insulating gloves, a face shield, and eye protection. Providers should also inform patients about the necessity of using a backflow preventive device in the piping and advise against changing or forcing connections.

Patients must be reminded to close the valve after each use and when the container is empty, and to always keep the container in an upright position. They should read and follow the Safety Data Sheet (SDS) prior to use to ensure safe handling.

In the event of an emergency, healthcare providers should instruct patients on first aid measures. If Nitrogen is inhaled, patients should be removed to fresh air and kept comfortable for breathing. If Nitrogen comes into contact with the skin, patients should thaw any frosted areas with lukewarm water without rubbing the affected area and seek immediate medical advice or attention.

Storage and Handling

The product is supplied in a container that must be kept in an upright position at all times. It is essential to use and store the product exclusively outdoors or in a well-ventilated area to ensure safety and compliance with handling guidelines. After each use and when the container is empty, the valve should be closed to prevent any accidental release of contents.

For safe handling, personnel are required to wear cold insulating gloves, a face shield, and eye protection. Prior to use, it is imperative to read and follow the Safety Data Sheet (SDS) to understand the necessary precautions and safety measures associated with the product.

Additional Clinical Information

The route of administration for the medication is via respiratory inhalation. There are no additional details available regarding laboratory tests, abuse information, patient counseling, or postmarketing experience.

FDA Insert (PDF)

This document is the official FDA-approved prescribing information for Nitrogen as submitted by Welders Supply Company. It includes detailed information about indications, dosage, contraindications, warnings, and clinical pharmacology.

View full prescribing information (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Nitrogen, retrieved by a validated AI data-extraction workflow.

All FDA-approved dosage forms and strengths are listed in the Packaging & NDC Codes section above. Regulatory status, pharmacologic class (EPC), and mechanism of action (MoA) were cross-checked against the FDA Orange Book (NDA205766) and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.