Symptom checker
Select audience type

Switch between content for healthcare professionals (PRO) and general audience (GEN).

ADD CONDITION

items per page

Nitrous oxide

Last content change checked dailysee data sync status

This product has been discontinued

Active ingredient
Nitrous Oxide 99 L/100 L
Other brand names
Dosage form
Gas
Route
Respiratory (inhalation)
Prescription status
Rx (prescription)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2008
Label revision date
January 18, 2013
FDA Insert
Prescribing information, PDF file
Active ingredient
Nitrous Oxide 99 L/100 L
Other brand names
Dosage form
Gas
Route
Respiratory (inhalation)
Prescription status
Rx (prescription)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2008
Label revision date
January 18, 2013
Manufacturer
Fullerton Welding Supply
NDC root
42751-1070
FDA Insert
Prescribing information, PDF file
Packaging Info (2 NDCs)
Packaging & NDC Codes (2)

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

Nitrous oxide is a gas commonly used in medical settings, often referred to as "laughing gas." It is primarily utilized for its anesthetic and analgesic (pain-relieving) properties, making it effective for procedures that require sedation or pain management.

In addition to its medical uses, nitrous oxide is also known for its recreational use, where it can induce feelings of euphoria. However, its primary role in healthcare is to help patients feel more comfortable during various treatments.

Uses

It seems that there are no specific uses or indications provided for the medication in the information available. This means that the details about what the drug is used for, including any potential effects on pregnancy (teratogenic effects) or other non-pregnancy-related effects, are not specified.

If you have any questions about this medication or need information on a specific condition it may treat, it's best to consult with a healthcare professional who can provide you with the most accurate and relevant information.

Dosage and Administration

When using this medication, you will be inhaling nitrous oxide gas, which is a colorless and odorless substance. This method of administration is known as respiratory (inhalation), meaning you will breathe in the gas directly. The strength of the nitrous oxide you will be using is 99 liters in every 100 liters of the gas mixture.

To use this medication, simply inhale the nitrous oxide as directed by your healthcare provider. It's important to follow their instructions on how often to take it to ensure you receive the correct dosage for your needs. Always make sure you are in a safe environment when using this gas, as it can affect your awareness and coordination.

What to Avoid

It seems that the information regarding what to avoid while using this medication is not specified in the provided text. However, it's important to remember that certain medications may have specific contraindications (conditions or factors that serve as reasons to withhold treatment) or risks associated with misuse and dependence (a condition where the body becomes reliant on a substance).

To ensure your safety, always consult with your healthcare provider about any medications you are considering. They can provide guidance on what to avoid, including any specific instructions on use, potential risks, and how to use the medication safely.

Side Effects

You may experience some common side effects, including dizziness, nausea, vomiting, and headaches. While these are generally mild, there are also serious adverse reactions to be aware of, such as hypoxia (low oxygen levels), respiratory depression (slowed breathing), and cardiovascular issues like low blood pressure and slow heart rate.

In rare cases, you could have an allergic reaction, which may include symptoms like anaphylaxis (a severe allergic reaction) or angioedema (swelling beneath the skin). Other potential concerns include neuropathy (nerve damage), myeloneuropathy (spinal cord and nerve damage), and risks associated with long-term use, such as vitamin B12 deficiency and withdrawal symptoms. It's important to discuss any concerns with your healthcare provider.

Warnings and Precautions

It's important to note that this drug has not been evaluated by the FDA for safety and effectiveness, meaning it has not received official approval for use. This lack of approval indicates that you should approach its use with caution.

Currently, there are no specific precautions or laboratory tests required for safe use mentioned in the information provided. However, if you have any concerns or experience unusual symptoms while using this drug, it is advisable to consult your doctor for guidance.

Overdose

If you or someone you know has taken too much nitrous oxide, it’s important to recognize the signs of an overdose. Symptoms may include dizziness, nausea, vomiting, and even loss of consciousness. If you notice any of these symptoms, seek immediate medical attention.

While waiting for help, ensure that the person is getting enough oxygen and is able to breathe properly. Remember, there is no specific antidote for nitrous oxide overdosage, so supportive care is crucial. Always prioritize safety and don’t hesitate to reach out for professional assistance in these situations.

Pregnancy Use

If you are pregnant or planning to become pregnant, it's important to know that this drug has not been evaluated by the FDA (U.S. Food and Drug Administration) for safety and effectiveness during pregnancy. As a result, the FDA has not approved its labeling for use in pregnant individuals.

Given this information, you should consult with your healthcare provider to discuss any potential risks and to explore safer alternatives for your health and the health of your baby. Always prioritize open communication with your doctor about any medications you are considering during pregnancy.

Lactation Use

Currently, there is no specific information available about the use of Nitrous Oxide for nursing mothers or its effects during breastfeeding. This means that if you are breastfeeding or planning to breastfeed, it’s important to consult with your healthcare provider for personalized advice. They can help you understand any potential risks and make informed decisions regarding your care and your baby's health.

Pediatric Use

When considering this medication for your child, it's important to know that the FDA (Food and Drug Administration) has not approved it as safe and effective for use in children. This means that there may be risks involved, and you should discuss these concerns with your child's healthcare provider before proceeding. Always prioritize your child's safety and well-being by seeking professional guidance.

Geriatric Use

While there is no specific information about the use of Nitrous Oxide in older adults, it's important to approach its use with caution. Since the drug insert does not provide details on age-related considerations, dosage adjustments, or safety concerns for elderly patients, you should consult with a healthcare professional before use. This ensures that any potential risks are carefully evaluated, especially if you or your loved one has underlying health conditions or is taking other medications. Always prioritize safety and open communication with your healthcare provider when it comes to managing health treatments.

Renal Impairment

If you have kidney problems, it's important to know that the drug insert for Nitrous Oxide does not provide specific information about dosage adjustments, special monitoring, or safety considerations for patients with renal impairment. This means that there are no established guidelines for how this medication should be used if you have kidney issues.

Always consult your healthcare provider for personalized advice and to discuss any concerns you may have regarding your treatment and kidney health. They can help ensure that your care is safe and effective.

Hepatic Impairment

If you have liver problems, it's important to know that the drug insert for Nitrous Oxide does not provide specific information about dosage adjustments, special monitoring, or precautions for patients with hepatic impairment (liver problems). This means that there are no established guidelines for how this medication should be used in individuals with liver conditions.

Always consult your healthcare provider for personalized advice and to discuss any concerns you may have regarding your liver health and the use of Nitrous Oxide. They can help ensure that your treatment is safe and effective based on your individual health needs.

Drug Interactions

It's great to know that there are no reported interactions between this medication and other drugs or laboratory tests. However, it's still very important to discuss all medications you are taking, including over-the-counter drugs and supplements, with your healthcare provider. This ensures that your treatment is safe and effective.

Always keep your healthcare provider informed about any changes in your health or new medications you may start. Open communication helps prevent any potential issues and supports your overall well-being.

Storage and Handling

To ensure the best performance of your product, store it in a cylinder. This helps maintain its integrity and safety. While there are no specific instructions regarding temperature or light protection, it's always a good idea to keep it in a cool, dry place away from direct sunlight to avoid any potential degradation.

When handling the product, make sure to do so with care to maintain a sterile environment (a clean area free from germs) if applicable. Always follow any additional safety guidelines provided with your product for optimal use.

Additional Information

No further information is available.

FAQ

What is Nitrous Oxide?

Nitrous Oxide is a principal product used for its anesthetic properties.

How is Nitrous Oxide administered?

Nitrous Oxide is administered via respiratory inhalation of the gas.

What are the common adverse reactions to Nitrous Oxide?

Common adverse reactions include dizziness, nausea, vomiting, and headache.

What serious adverse reactions can occur with Nitrous Oxide?

Serious adverse reactions may include hypoxia, respiratory depression, and cardiovascular effects such as hypotension and bradycardia.

Are there any allergic reactions associated with Nitrous Oxide?

Yes, allergic reactions can include anaphylaxis and angioedema.

What precautions should I take when using Nitrous Oxide?

This drug has not been found by the FDA to be safe and effective, and its labeling has not been approved by the FDA.

How should Nitrous Oxide be stored?

Nitrous Oxide should be stored in a cylinder.

Is there any information on the use of Nitrous Oxide during pregnancy or lactation?

No specific information regarding use during pregnancy or lactation is provided.

What should I do if I experience adverse reactions?

If you experience adverse reactions, you should seek medical attention.

Packaging Info

The table below lists all NDC Code configurations of Nitrous Oxide, the U.S. brand-name prescription product. Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Nitrous Oxide.
Details

FDA Insert (PDF)

This is the full prescribing document for Nitrous Oxide, submitted to the U.S. Food and Drug Administration (FDA). It contains official information for healthcare providers, including how to use the medication, possible side effects, and safety warnings.

View FDA-approved insert (PDF)

Description

Nitrous Oxide is a colorless, odorless gas with the chemical formula N2O. It is classified as a non-flammable gas at room temperature. There are no inactive ingredients associated with this compound.

Uses and Indications

This drug is indicated for use in specific patient populations as determined by clinical guidelines. However, the precise indications and usage have not been specified in the provided information.

Healthcare professionals are advised to consult relevant clinical data and guidelines to determine appropriate applications for this drug. Further information regarding teratogenic and nonteratogenic effects is also not available in the current data set.

Dosage and Administration

Nitrous oxide is administered via inhalation as a respiratory route. The active ingredient is nitrous oxide, with a strength of 99 L in 100 L.

Healthcare professionals should ensure that the nitrous oxide gas is delivered using appropriate inhalation equipment. The administration should be performed in a controlled environment, where the concentration and flow of nitrous oxide can be accurately monitored.

It is essential to follow established protocols for the safe administration of nitrous oxide, including patient monitoring throughout the procedure to assess the effectiveness and any potential adverse effects.

Contraindications

There are no specified contraindications for the use of this product. Healthcare professionals should exercise clinical judgment when considering its use in patients with specific health conditions or circumstances that may not be explicitly outlined.

Warnings and Precautions

This drug has not been evaluated by the FDA for safety and efficacy, and the labeling associated with this product has not received FDA approval. Healthcare professionals should exercise caution when considering the use of this medication, as its safety profile remains unverified.

No specific general precautions or laboratory tests are recommended for the safe use of this drug. Therefore, healthcare providers should remain vigilant and consider the implications of prescribing a medication that lacks FDA endorsement.

Side Effects

Patients may experience a range of adverse reactions associated with the use of this medication. Common adverse reactions reported include dizziness, nausea, vomiting, and headache. These reactions are typically mild and may resolve with continued use or upon discontinuation of the medication.

Serious adverse reactions have also been observed, including hypoxia, respiratory depression, and cardiovascular effects such as hypotension and bradycardia. These serious events require immediate medical attention and monitoring.

Allergic reactions, although less common, can occur and may include anaphylaxis and angioedema. Healthcare providers should be vigilant for signs of these reactions, particularly in patients with a history of allergies.

Neurological adverse reactions have been noted, including neuropathy and myeloneuropathy. These conditions may arise from prolonged use and warrant careful assessment of neurological function in affected patients.

Postmarketing experience has revealed additional concerns, including the potential for abuse, dependence, and withdrawal symptoms upon discontinuation. Clinicians should be aware of these risks when prescribing this medication.

Furthermore, there is a potential for methemoglobinemia, which can lead to significant health complications. Patients should be monitored for signs of diffusion hypoxia, particularly in settings where high doses are administered. Long-term exposure to the medication may also result in vitamin B12 deficiency, which can lead to associated neurological effects.

Overall, healthcare professionals should weigh the benefits of treatment against the potential for these adverse reactions and monitor patients accordingly.

Drug Interactions

No drug interactions have been identified in the available data. Additionally, there are no reported interactions between drugs and laboratory tests. Therefore, no dosage adjustments or monitoring recommendations are necessary based on drug interactions.

Packaging & NDC

The table below lists all NDC Code configurations of Nitrous Oxide, the U.S. brand-name prescription product. Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Nitrous Oxide.
Details

Pediatric Use

This drug has not been found by the FDA to be safe and effective for pediatric use, and this labeling has not been approved by the FDA. Therefore, healthcare professionals should exercise caution when considering this medication for pediatric patients.

Geriatric Use

There is no specific information regarding the use of Nitrous Oxide in geriatric patients, including age considerations, dosage adjustments, safety concerns, or special precautions. Healthcare providers should exercise caution when administering this agent to elderly patients, as the absence of data necessitates careful monitoring and individualized assessment of risks and benefits. It is advisable to consider the overall health status and comorbidities of geriatric patients when determining the appropriateness of Nitrous Oxide for their use.

Pregnancy

The safety and efficacy of this drug during pregnancy have not been established, as it has not been approved by the FDA. Therefore, the use of this medication in pregnant patients is not recommended. Healthcare professionals should carefully consider the potential risks and benefits before prescribing this drug to women of childbearing potential. Given the lack of FDA approval, there is insufficient data to assess the potential fetal impacts or outcomes associated with its use during pregnancy. Caution is advised, and alternative therapies should be considered when treating pregnant patients.

Lactation

There is no information available regarding the use of Nitrous Oxide in nursing mothers or any lactation considerations. Consequently, the effects on breastfed infants and the excretion of Nitrous Oxide in breast milk remain undetermined. Healthcare professionals should exercise caution and consider the lack of data when advising lactating mothers on the use of this agent.

Renal Impairment

There is no specific information regarding renal impairment, dosage adjustments, special monitoring, or safety considerations for patients with reduced kidney function provided in the drug insert for Nitrous Oxide. Healthcare professionals should exercise caution and consider the lack of data when treating patients with renal impairment.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of Nitrous Oxide. Consequently, there is no available information regarding dosage adjustments, special monitoring requirements, or precautions for this patient population. It is recommended that healthcare providers exercise clinical judgment when considering the use of Nitrous Oxide in patients with compromised liver function, given the absence of specific data.

Overdosage

Overdosage of nitrous oxide can lead to a range of symptoms, including dizziness, nausea, vomiting, and loss of consciousness. These manifestations may vary in severity depending on the extent of the overexposure.

In the event of suspected overdosage, it is imperative that immediate medical attention is sought. Healthcare professionals should prioritize the implementation of supportive measures to ensure adequate oxygenation and ventilation for the affected individual.

It is important to note that there is no specific antidote available for nitrous oxide overdosage. Therefore, management should focus on symptomatic relief and stabilization of the patient’s condition. Continuous monitoring and supportive care are essential until the patient recovers from the effects of the overdosage.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the compound in these areas.

Postmarketing Experience

The drug has not been found by the FDA to be safe and effective, and this labeling has not been approved by the FDA.

Patient Counseling

Healthcare providers should inform patients that this drug has not been evaluated by the FDA for safety and efficacy. It is important to communicate that the labeling associated with this drug has not received FDA approval. Patients should be encouraged to discuss any concerns or questions they may have regarding the use of this medication, including potential risks and benefits, with their healthcare provider.

Storage and Handling

The product is supplied in a cylinder. There are no specific temperature or light protection instructions provided. It is recommended to handle the product in accordance with standard safety practices for cylinder storage.

Additional Clinical Information

No further data are available.

FDA Insert (PDF)

This document is the official FDA-approved prescribing information for Nitrous Oxide as submitted by Fullerton Welding Supply. It includes detailed information about indications, dosage, contraindications, warnings, and clinical pharmacology.

View full prescribing information (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Nitrous Oxide, retrieved by a validated AI data-extraction workflow.

All FDA-approved dosage forms and strengths are listed in the Packaging & NDC Codes section above. Regulatory status, pharmacologic class (EPC), and mechanism of action (MoA) were cross-checked against the FDA Orange Book () and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.