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Afrin No Drip

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Active ingredient
Oxymetazoline Hydrochloride 0.05 g/100 mL
Other brand names
Drug class
Vasoconstrictor
Dosage form
Spray, Metered
Route
Nasal
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2000
Label revision date
December 5, 2025
Drug Information (PDF)
Prescribing information, PDF file
Active ingredient
Oxymetazoline Hydrochloride 0.05 g/100 mL
Other brand names
Drug class
Vasoconstrictor
Dosage form
Spray, Metered
Route
Nasal
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2000
Label revision date
December 5, 2025
Manufacturer
Bayer HealthCare LLC.
Registration number
M012
NDC root
11523-1783
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info (3 NDCs)
Packaging & NDC Codes (3)

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

This medication is designed to temporarily relieve nasal congestion caused by conditions such as the common cold, hay fever, and upper respiratory allergies. It works by shrinking swollen nasal membranes, which helps you breathe more freely and alleviates sinus congestion and pressure. If you're experiencing discomfort from nasal congestion, this drug may provide the relief you need.

Uses

If you're dealing with nasal congestion from a common cold, hay fever, or upper respiratory allergies, this medication can help provide temporary relief. It works by shrinking swollen nasal membranes, allowing you to breathe more freely. Additionally, it can relieve sinus congestion and pressure, making it easier for you to feel comfortable.

Dosage and Administration

Before using this medication, make sure to shake the bottle well. If it’s your first time using it, you’ll need to prepare the spray by removing the protective cap and priming the pump. To do this, press the pump down firmly several times until you see a fine mist. When you’re ready to spray, hold the bottle with your thumb at the bottom and your fingers on the nozzle. Insert the nozzle into your nostril without tilting your head, then press down firmly on the rim while sniffing deeply.

For adults and children aged 6 to under 12 years, you can use 2 or 3 sprays in each nostril, but make sure not to do this more than every 10 to 12 hours. It’s important not to exceed 2 doses in a 24-hour period. If you have a child under 6 years old, please consult a doctor before use. After using the spray, remember to wipe the nozzle clean to keep it in good condition.

What to Avoid

It's important to use this medication responsibly to avoid potential issues. You should not use it for more than three days, and always follow the directions provided. Using it longer than recommended can lead to nasal congestion returning or worsening. Additionally, sharing this medication with others can increase the risk of spreading infections, so it's best to keep it for your personal use only. Remember, using more than directed can also lead to complications, so please adhere to the guidelines for safe use.

Side Effects

You may experience some temporary discomfort while using this product, which can include burning, stinging, sneezing, or an increase in nasal discharge. These side effects are generally mild and should resolve on their own.

However, if your symptoms persist, it’s important to stop using the product and consult a doctor for further advice.

Warnings and Precautions

Before using this medication, it's important to consult your doctor if you have any of the following conditions: heart disease, high blood pressure, thyroid disease, diabetes, or difficulty urinating due to an enlarged prostate gland. Always follow the directions carefully—do not exceed the recommended dose or use it for more than three days, as doing so may worsen nasal congestion. You might experience temporary discomfort like burning, stinging, sneezing, or increased nasal discharge. Additionally, sharing this medication with others can lead to the spread of infection.

Keep this medication out of reach of children. If a child accidentally swallows it, seek medical help or contact a Poison Control Center immediately. If your symptoms do not improve, stop using the medication and reach out to your doctor for further advice.

Overdose

It's important to keep this medication out of reach of children. If a child accidentally swallows it, you should seek medical help immediately or contact a Poison Control Center.

In case of an overdose, you may notice symptoms such as unusual drowsiness, confusion, or difficulty breathing. If you or someone else experiences these signs, it's crucial to get emergency assistance right away. Always prioritize safety and act quickly if an overdose is suspected.

Pregnancy Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using this medication. They can provide guidance on whether it’s safe for you and your baby. Always prioritize your health and the health of your child by seeking expert advice.

Lactation Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using any medication. This ensures that you understand any potential risks and can make informed decisions about your health and the health of your baby. Always prioritize open communication with your doctor regarding your breastfeeding journey.

Pediatric Use

When using this medication for children aged 6 to under 12 years, you can administer 2 or 3 sprays in each nostril, but only with adult supervision. It's important to space these doses at least 10 to 12 hours apart and not to exceed 2 doses in a 24-hour period.

For children under 6 years of age, you should consult a doctor before use. This ensures that the medication is safe and appropriate for your child's specific needs. Always prioritize your child's health and follow these guidelines carefully.

Geriatric Use

When considering this medication, it's important to consult with your doctor, especially if you or an older adult has any existing health conditions. This includes heart disease, high blood pressure, thyroid issues, diabetes, or difficulties urinating due to an enlarged prostate. These conditions can be more common in older adults and may affect how the medication works or how safe it is for you.

Currently, there is no specific information available regarding the use of this medication in older adults. Therefore, it's crucial to have an open discussion with your healthcare provider to ensure that it is appropriate for your situation and to determine the right dosage for your needs.

Renal Impairment

If you have kidney problems, it's important to know that the information provided does not include specific guidelines for dosage adjustments, special monitoring, or safety considerations related to renal impairment (kidney issues). This means that there are no tailored recommendations for how your treatment may need to change based on your kidney function.

Always consult your healthcare provider for personalized advice and to ensure that your treatment is safe and effective for your specific condition. They can help determine the best approach for managing your health, especially if you have concerns about your kidneys.

Hepatic Impairment

If you have liver problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or precautions for your condition. This means that there are no tailored guidelines for how this medication may affect you differently due to your liver health.

Always consult your healthcare provider for personalized advice and to ensure that any medication you take is safe and appropriate for your liver condition. They can help monitor your liver function and make any necessary adjustments to your treatment plan.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you. Always share your complete list of medications and any recent lab tests to avoid any potential issues. Your health and safety should always come first.

Storage and Handling

To ensure the best performance of your product, store it in a cool, dry place at a temperature between 20° to 25°C (68° to 77°F). This temperature range helps maintain the product's effectiveness and safety. It's also important to keep the original carton, as it contains valuable information about the product's labeling that you may need for future reference.

When handling the product, always do so with clean hands and in a clean environment to avoid contamination. Following these guidelines will help you use the product safely and effectively.

Additional Information

The medication is administered through the nasal route, meaning you will use a spray or similar method to deliver the drug directly into your nose. There are no additional details available regarding laboratory tests, abuse potential, patient counseling, or experiences reported after the drug has been on the market.

FAQ

What conditions does this drug temporarily relieve?

This drug temporarily relieves nasal congestion due to common cold, hay fever, and upper respiratory allergies, as well as sinus congestion and pressure.

How does this drug work?

It shrinks swollen nasal membranes, allowing you to breathe more freely.

What are the dosage instructions for children aged 6 to under 12?

Children aged 6 to under 12 years should use 2 or 3 sprays in each nostril not more often than every 10 to 12 hours, and should not exceed 2 doses in any 24-hour period.

What should I do if I have heart disease or high blood pressure?

You should ask a doctor before using this drug if you have heart disease, high blood pressure, thyroid disease, diabetes, or trouble urinating due to an enlarged prostate gland.

What are the side effects of this drug?

Temporary discomfort such as burning, stinging, sneezing, or an increase in nasal discharge may occur.

How long can I use this drug?

Do not use this drug for more than 3 days, and use only as directed to avoid worsening nasal congestion.

What should I do if symptoms persist?

Stop using the drug and ask a doctor if your symptoms persist.

Is this drug safe to use during pregnancy or breastfeeding?

If you are pregnant or breastfeeding, you should ask a health professional before use.

What should I do if I accidentally swallow the drug?

Keep it out of reach of children, and if swallowed, get medical help or contact a Poison Control Center right away.

How should I store this drug?

Store the drug between 20° to 25°C (68° to 77°F) and retain the carton for future reference on full labeling.

Packaging Info

Below are the non-prescription pack sizes of Afrin No Drip (oxymetazoline hydrochloride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Afrin No Drip.
Details

Drug Information (PDF)

This file contains official product information for Afrin No Drip, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the drug.

Uses and Indications

This drug is indicated for the temporary relief of nasal congestion associated with the common cold, hay fever, and upper respiratory allergies. It also provides temporary relief from sinus congestion and pressure. Additionally, this medication acts to shrink swollen nasal membranes, facilitating easier breathing.

There are no teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

Adults and children aged 6 to under 12 years of age, when administered under adult supervision, may receive 2 or 3 sprays in each nostril. Dosing should not occur more frequently than every 10 to 12 hours, and it is important not to exceed 2 doses within a 24-hour period. For children under 6 years of age, consultation with a physician is recommended prior to use.

Prior to administration, the bottle should be shaken well. For first-time use, the protective cap must be removed from the tip, and the metered pump should be primed by firmly depressing the pump several times. To administer the spray, the healthcare professional should instruct the patient to hold the bottle with the thumb at the base and the nozzle positioned between the first and second fingers. The nozzle should be inserted into the nostril without tilting the head. The rim should be fully depressed with a firm, even stroke while the patient sniffs deeply. After use, the nozzle should be wiped clean to maintain hygiene.

Contraindications

Use is contraindicated in the following situations:

  • Use is not recommended for more than 3 consecutive days due to the risk of nasal congestion recurrence or worsening.

  • Use is contraindicated if the product is intended for more than the directed dosage, as this may lead to adverse effects.

  • The product should not be used by multiple individuals from the same container to prevent the spread of infection.

Warnings and Precautions

Healthcare professionals should be aware of the following warnings and precautions associated with the use of this medication.

Patients should be advised to consult a physician prior to use if they have any of the following conditions: heart disease, high blood pressure, thyroid disease, diabetes, or difficulty urinating due to an enlarged prostate gland. These conditions may increase the risk of adverse effects or complications.

It is imperative that patients adhere strictly to the recommended dosage. The medication should not be used for more than three consecutive days, as prolonged or frequent use may lead to a recurrence or worsening of nasal congestion. Patients may experience temporary discomfort, including burning, stinging, sneezing, or an increase in nasal discharge. Additionally, the use of this container by multiple individuals may pose a risk of spreading infection.

In the event of accidental ingestion, it is crucial to keep the medication out of reach of children. If swallowed, immediate medical assistance should be sought, or contact with a Poison Control Center is recommended.

Patients should be instructed to discontinue use and consult a healthcare provider if symptoms persist. This precaution is essential to ensure appropriate management of their condition and to prevent potential complications.

Side Effects

Patients using this product may experience temporary discomfort, which can include sensations of burning, stinging, sneezing, or an increase in nasal discharge. These reactions are generally mild and transient.

If symptoms persist, patients are advised to discontinue use and consult a healthcare professional for further evaluation and guidance.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there are no known interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Afrin No Drip (oxymetazoline hydrochloride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Afrin No Drip.
Details

Pediatric Use

Pediatric patients aged 6 to under 12 years may receive 2 or 3 sprays in each nostril, administered no more frequently than every 10 to 12 hours. It is important not to exceed 2 doses within a 24-hour period. For children under 6 years of age, consultation with a healthcare professional is advised prior to use.

Geriatric Use

Elderly patients may require special consideration when using this medication, as no specific information regarding geriatric use is provided in the prescribing information. It is essential for healthcare providers to exercise caution and evaluate the individual health status of geriatric patients prior to prescribing.

Particular attention should be given to patients aged 65 and older who have underlying health conditions. Warnings indicate that patients should consult a healthcare professional before use if they have a history of heart disease, high blood pressure, thyroid disease, diabetes, or difficulty urinating due to an enlarged prostate gland. These conditions may be more prevalent in elderly patients and could influence the safety and efficacy of the medication.

Monitoring and potential dose adjustments may be necessary based on the patient's overall health and response to treatment. Healthcare providers are advised to assess the risks and benefits of therapy in geriatric patients, ensuring that any treatment plan is tailored to their specific needs.

Pregnancy

Pregnant patients and those who are breastfeeding should consult a healthcare professional prior to using this medication. The potential risks and benefits must be carefully weighed, as the effects on fetal outcomes and lactation are not fully established. It is essential for women of childbearing potential to seek medical advice to ensure safe use during pregnancy and lactation.

Lactation

Lactating mothers are advised to consult a health professional prior to using this medication. There is currently no available data on the excretion of this drug in human breast milk or its effects on breastfed infants. Therefore, caution is recommended when administering this medication to lactating individuals.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the available prescribing information. There are no dosage adjustments, special monitoring requirements, or safety considerations outlined for individuals with reduced kidney function. Healthcare professionals should exercise caution and consider the lack of data when prescribing to this patient population.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

In the event of an overdosage, it is imperative to keep the product out of reach of children. Should ingestion occur, immediate medical assistance is required. Healthcare professionals should advise caregivers to contact a Poison Control Center without delay.

Prompt action is crucial in managing potential overdosage situations to mitigate risks and ensure patient safety.

Nonclinical Toxicology

If pregnant or breastfeeding, it is advised to consult a health professional prior to use. Temporary discomfort may occur, including symptoms such as burning, stinging, sneezing, or an increase in nasal discharge. No relevant information regarding carcinogenicity, mutagenicity, or impairment of fertility has been provided in the insert. Additionally, there is no relevant data available concerning animal pharmacology and toxicology.

Postmarketing Experience

Postmarketing experience has indicated that the use of this product may be associated with temporary discomfort, including symptoms such as burning, stinging, sneezing, or an increase in nasal discharge. These events have been reported voluntarily or identified through surveillance programs.

Patient Counseling

Healthcare providers should advise patients to keep this product out of reach of children to prevent accidental ingestion. Instruct patients that if the product is swallowed, they should seek medical help or contact a Poison Control Center immediately.

Patients should be informed to stop using the product and consult a doctor if symptoms persist. When using this product, it is essential to adhere strictly to the recommended dosage and duration. Patients should not use more than directed and should not use the product for more than three days. Emphasize that frequent or prolonged use may lead to a recurrence or worsening of nasal congestion.

Inform patients that temporary discomfort, such as burning, stinging, sneezing, or an increase in nasal discharge, may occur during use. Additionally, caution should be taken as the use of this container by more than one person may spread infection.

Healthcare providers should also encourage patients to consult a doctor before using this product if they have any of the following conditions: heart disease, high blood pressure, thyroid disease, diabetes, or trouble urinating due to an enlarged prostate gland.

Storage and Handling

The product is supplied in packaging that includes specific NDC numbers, which should be referenced for identification. It is essential to store the product at a temperature range of 20° to 25°C (68° to 77°F) to maintain its integrity and efficacy.

Healthcare professionals are advised to retain the carton for future reference regarding the full labeling information, ensuring that all necessary details are readily accessible for proper handling and administration.

Additional Clinical Information

The route of administration for the medication is nasal. There are no additional details available regarding laboratory tests, abuse information, patient counseling, or postmarketing experience.

Drug Information (PDF)

This file contains official product information for Afrin No Drip, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Afrin No Drip, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

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Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.