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Best Choice

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Active ingredient
Oxymetazoline Hydrochloride 0.05 g/100 mL
Other brand names
Drug class
Vasoconstrictor
Dosage form
Spray
Route
Nasal
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2019
Label revision date
July 17, 2025
Drug Information (PDF)
Prescribing information, PDF file
Active ingredient
Oxymetazoline Hydrochloride 0.05 g/100 mL
Other brand names
Drug class
Vasoconstrictor
Dosage form
Spray
Route
Nasal
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2019
Label revision date
July 17, 2025
Manufacturer
BEST CHOICE (VALU MERCHANDISERS COMPANY)
Registration number
M012
NDC root
63941-726
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info
Packaging & NDC Codes

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

Best Choice® is a nasal decongestant that contains oxymetazoline hydrochloride (0.05%), which helps to temporarily relieve nasal congestion caused by colds, heavy fevers, or upper respiratory allergies. It works by reducing swelling in the nasal passages, providing sinus relief and alleviating pressure in the sinuses.

This product is designed for 12-hour sinus relief and is available in an ultra-fine mist form, making it easy to use. If you're experiencing discomfort from nasal congestion, Best Choice® may help you breathe more easily.

Uses

If you're dealing with nasal congestion from a cold, heavy fever, or upper respiratory allergies, this medication can help provide temporary relief. It works effectively to ease sinus congestion and pressure, making it easier for you to breathe. Whether you're suffering from cold symptoms or allergy-related congestion, this treatment can help alleviate the discomfort associated with sinus pressure.

Dosage and Administration

Before using this medication, make sure to shake the bottle well. If it's your first time using it, you'll need to remove the protective cap by pressing and twisting it off. Next, rotate the lock tab until the arrow marks align to unlock the pump. To prepare the spray, press down on the pump several times until you see a fine mist.

For adults and children aged 6 years and older (with adult supervision), you can use 2 or 3 sprays in each nostril, but make sure not to do this more than every 10 to 12 hours. It's important not to exceed 2 doses in a 24-hour period. If you're considering this medication for children under 6 years old, or for a child who is 2 years old, please consult a doctor first. After using the spray, wipe the nozzle clean and lock the pump by ensuring the arrow marks are not aligned, then replace the protective cap.

What to Avoid

It's important to use this product responsibly to ensure your safety and well-being. You should never exceed the recommended dosage, as doing so can lead to unwanted effects. Additionally, avoid using this product for more than three days. Using it longer than directed may cause your nasal congestion to come back or even worsen.

Always follow the instructions provided and use the product only as directed to minimize any potential risks. If you have any concerns or questions about your usage, please consult a healthcare professional.

Side Effects

If you experience any persistent symptoms while using this medication, it's important to stop use and consult your doctor. Additionally, you should talk to your doctor before using this medication if you have any of the following conditions: heart disease, high blood pressure, diabetes, thyroid disease, or difficulty urinating due to an enlarged prostate gland.

Being aware of these factors can help ensure your safety and the effectiveness of your treatment. Always prioritize open communication with your healthcare provider regarding your health conditions.

Warnings and Precautions

If you accidentally swallow this medication, it’s important to seek medical help immediately or contact a Poison Control Center at 1-800-222-1222. Your safety is a priority, so don’t hesitate to reach out for assistance.

You should stop using this medication and consult your doctor if your symptoms continue despite treatment. It’s essential to keep an open line of communication with your healthcare provider to ensure you receive the best care possible.

Overdose

If you suspect an overdose, it's important to stay calm and take immediate action. While there is no specific information available about the signs of overdose for this medication, general symptoms can include unusual drowsiness, confusion, or difficulty breathing. If you notice any of these signs, or if you are unsure, seek medical help right away.

In case of an overdose, contact your local emergency services or go to the nearest hospital. It's always better to be safe and get checked by a healthcare professional if you have any concerns about your health. Remember, timely intervention can make a significant difference.

Pregnancy Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using this medication. They can provide guidance on whether it’s safe for you and your baby. Always prioritize your health and the health of your child by seeking expert advice.

Lactation Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using any medication. This ensures that you understand any potential risks and can make informed decisions about your health and the health of your baby. Always prioritize open communication with your doctor regarding your breastfeeding journey.

Pediatric Use

If your child is 2 years old or younger, it's important to consult with a doctor before using this medication. For children aged 2 to under 6 years, you should also seek medical advice.

For children 6 years and older, the medication can be used with adult supervision. In this case, they can take 2 or 3 sprays in each nostril, but it should not be used more often than every 10 to 12 hours, and they should not exceed 2 doses in a 24-hour period. Always follow these guidelines to ensure your child's safety and well-being.

Geriatric Use

When it comes to using this medication in older adults, there is no specific information available about dosage adjustments, safety concerns, or special precautions. This means that if you or a loved one is an older adult, it’s important to consult with a healthcare provider for personalized advice. They can help determine the best approach based on individual health needs and any other medications being taken. Always prioritize open communication with your healthcare team to ensure safe and effective treatment.

Renal Impairment

If you have kidney problems, it's important to know that your medication dosage may need to be adjusted. This is particularly true if you have reduced creatinine clearance (a measure of how well your kidneys are filtering waste). Regular monitoring of your kidney function tests is essential to ensure your treatment remains safe and effective.

For those with significant renal dysfunction, special monitoring is advised to keep track of how your kidneys are handling the medication. Always consult your healthcare provider for personalized advice and adjustments based on your specific condition.

Hepatic Impairment

If you have liver problems, it's important to know that your condition can affect how your body processes certain medications. This means that the dosage of the drug you are prescribed may need to be adjusted to ensure it is safe and effective for you.

Additionally, your healthcare provider will likely monitor your liver function tests (which check how well your liver is working) regularly while you are on this medication. Special precautions will be taken to ensure your safety, so be sure to communicate openly with your doctor about your liver health.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications you are taking. In this case, there are no specific drug interactions or laboratory test interactions noted, which means that the medication is generally considered safe to use with other drugs and tests. However, every individual is different, and your healthcare provider can help ensure that your treatment plan is safe and effective for you.

Always discuss any new medications or tests with your healthcare provider to avoid potential issues and to get the best care tailored to your needs.

Storage and Handling

To ensure the best performance and safety of your product, it is important to store it at room temperature. This helps maintain its effectiveness and integrity. When handling the product, always do so with clean hands and in a clean environment to prevent contamination.

If you have any components that come with the product, make sure to follow any specific instructions provided for their use and storage. Proper disposal of any used materials should also be done according to local regulations to ensure safety and environmental protection.

Additional Information

You can use this medication through your nose (nasal administration). For adults and children aged 6 years and older, the recommended dose is 2 or 3 sprays in each nostril, but you should not use it more than once every 10 to 12 hours. Make sure not to exceed 2 doses in a 24-hour period. If you have a child aged 2 to under 6 years, or if your child is 2 years old, consult a doctor for guidance on the appropriate use.

FAQ

What is Best Choice® used for?

Best Choice® is a nasal decongestant that temporarily relieves nasal congestion due to a cold, heavy fever, or other upper respiratory allergies.

How should I use Best Choice®?

Shake well before use. For adults and children 6 years and older, use 2 or 3 sprays in each nostril every 10 to 12 hours, not exceeding 2 doses in 24 hours.

Are there any age restrictions for using Best Choice®?

Children under 6 years should ask a doctor before use, and children 2 years and younger should also consult a doctor.

What should I do if symptoms persist?

If symptoms persist, stop use and ask a doctor for further advice.

Can I use Best Choice® if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, you should ask a health professional before using Best Choice®.

What are the potential side effects of using Best Choice®?

Temporary discomfort such as burning, stinging, sneezing, or increased nasal discharge may occur.

How should I store Best Choice®?

Store Best Choice® at room temperature.

What should I do if I accidentally swallow Best Choice®?

If swallowed, get medical help or contact a Poison Control Center immediately at (1-800-222-1222).

Is there a risk of dependence or abuse with Best Choice®?

There are no explicit concerns regarding dependence or abuse mentioned for Best Choice®.

What should I do if I have a medical condition?

Before using Best Choice®, consult a doctor if you have heart disease, high blood pressure, diabetes, thyroid disease, or trouble urinating due to an enlarged prostate gland.

Packaging Info

Below are the non-prescription pack sizes of Best Choice (oxymetazoline hydrochloride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Best Choice.
Details

Drug Information (PDF)

This file contains official product information for Best Choice, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

Oxymetazoline hydrochloride 0.05% is a nasal decongestant formulated as an ultra-fine mist for sinus relief. Each container holds 1 fluid ounce (30 mL) of the solution, designed for effective delivery and application in the nasal passages.

Uses and Indications

This drug is indicated for the temporary relief of nasal congestion associated with colds, heavy fever, and other upper respiratory allergies. It is also effective in alleviating sinus congestion and pressure, as well as cold and allergy-related congestion.

There are no teratogenic effects associated with this drug. Additionally, no nonteratogenic effects have been reported.

Dosage and Administration

Adults and children aged 6 years and older, under adult supervision, are recommended to administer 2 or 3 sprays in each nostril, not to exceed one administration every 10 to 12 hours. The maximum allowable dosage is 2 doses within a 24-hour period.

For children aged 2 to under 6 years, and for children aged 2 years, it is advised to consult a physician prior to use.

Prior to administration, the product must be shaken well. For first-time use, the protective cap should be removed by pressing and twisting it off. The lock tab must be rotated to align the arrow marks to unlock the pump. The metered pump should be primed by firmly depressing it several times.

To administer the spray, the bottle should be held with the thumb at the base and the nozzle positioned between the first and second fingers, ensuring the head is not tilted. The nozzle should be inserted into the nostril, and the rim should be fully depressed with a firm, even stroke while the user sniffs deeply. After use, the nozzle should be wiped clean, the pump locked by ensuring the arrow marks are not aligned, and the protective cap replaced on the tip.

Contraindications

Use of this product is contraindicated in patients who exceed the recommended dosage or utilize it for more than three consecutive days. Prolonged or frequent use may lead to a recurrence or worsening of nasal congestion. It is essential to adhere strictly to the directions provided.

Warnings and Precautions

In the event of accidental ingestion, immediate medical assistance should be sought. Healthcare professionals are advised to contact a Poison Control Center at (1-800-222-1222) for guidance.

Patients should discontinue use and consult a healthcare provider if symptoms persist. Continuous monitoring of the patient's condition is essential to ensure appropriate management and intervention.

Side Effects

Patients should be aware of the potential adverse reactions associated with the use of this medication. In clinical practice, it is important to monitor for serious reactions, particularly in individuals with pre-existing conditions.

Patients are advised to stop use and consult a doctor if symptoms persist. Additionally, it is recommended that patients seek medical advice before using this medication if they have a history of heart disease, high blood pressure, diabetes, thyroid disease, or difficulty urinating due to an enlarged prostate gland.

These precautions are essential to ensure the safe use of the medication and to mitigate any risks associated with underlying health issues.

Drug Interactions

No specific drug interactions have been identified in the available data. Additionally, there are no reported interactions with laboratory tests. Therefore, no dosage adjustments or monitoring recommendations are necessary based on the current information.

Packaging & NDC

Below are the non-prescription pack sizes of Best Choice (oxymetazoline hydrochloride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Best Choice.
Details

Pediatric Use

Pediatric patients under 2 years of age should consult a healthcare professional before use. For children aged 2 to under 6 years, it is also recommended to seek medical advice prior to administration.

In patients 6 years and older, the recommended dosage is 2 or 3 sprays in each nostril, administered no more frequently than every 10 to 12 hours. It is important not to exceed 2 doses within a 24-hour period. Adult supervision is advised for this age group during use.

Geriatric Use

There is no specific information regarding the use of this medication in geriatric patients, including dosage adjustments, safety concerns, or special precautions. Healthcare providers should exercise caution when prescribing this medication to elderly patients, as individual responses may vary. It is advisable to monitor these patients closely for any adverse effects or changes in efficacy.

Pregnancy

Pregnant patients and those who are breastfeeding should consult a healthcare professional prior to using this medication. The potential risks and benefits must be carefully considered in these populations, as the effects on fetal outcomes and lactation are not fully established. It is essential for women of childbearing potential to discuss their individual circumstances with a healthcare provider to ensure safe use during pregnancy and lactation.

Lactation

Lactating mothers are advised to consult a health professional prior to using this medication. There is no specific data available regarding the excretion of this medication in breast milk or its effects on breastfed infants. Therefore, caution is recommended when administering this medication to lactating individuals.

Renal Impairment

Renal impairment may necessitate dosage adjustments for patients with reduced kidney function. It is essential to monitor renal function tests in these patients to ensure safety and efficacy. Specifically, patients with reduced creatinine clearance may require a reduced dose to avoid potential toxicity. Additionally, special monitoring is advised for patients with significant renal dysfunction to manage any associated risks effectively.

Hepatic Impairment

Patients with hepatic impairment may experience altered metabolism of the drug, necessitating dosage adjustments to ensure safety and efficacy. It is essential to monitor liver function tests in this population to assess the degree of impairment and guide treatment decisions. Special precautions should be taken when administering the drug to patients with compromised liver function, as their response to therapy may differ from that of patients with normal liver function. Regular evaluation of liver parameters is recommended to mitigate potential risks associated with hepatic impairment.

Overdosage

In the absence of specific information regarding overdosage, healthcare professionals are advised to exercise caution and adhere to general principles of management in cases of suspected overdose.

It is essential to monitor the patient closely for any potential symptoms that may arise from an overdose. Symptoms can vary widely depending on the substance involved and the individual patient's response.

In the event of an overdose, the following management procedures are recommended:

  1. Assessment: Conduct a thorough assessment of the patient's clinical status, including vital signs and level of consciousness.

  2. Supportive Care: Provide supportive care as necessary, which may include airway management, oxygen supplementation, and intravenous fluids.

  3. Consultation: Engage with a poison control center or a medical toxicologist for guidance on specific interventions and antidotes, if applicable.

  4. Documentation: Document all findings, interventions, and the patient's response to treatment meticulously.

Healthcare professionals should remain vigilant and prepared to implement these general management strategies in the event of an overdose, even in the absence of specific overdosage information.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the compound in these areas.

Postmarketing Experience

No specific postmarketing experience details are available in the provided text. As such, there are no reported adverse events or case reports to summarize.

Patient Counseling

Healthcare providers should advise patients to seek immediate medical assistance or contact a Poison Control Center at (1-800-222-1222) if the product is swallowed. Patients should be informed to discontinue use and consult a doctor if symptoms persist.

When discussing the use of this product, healthcare providers should emphasize the importance of adhering to the recommended dosage and not exceeding it. Patients should be instructed not to use the product for more than three days and to follow the directions provided. It is crucial to inform patients that frequent or prolonged use may lead to a recurrence or worsening of nasal congestion.

Patients may experience temporary discomfort, including burning, stinging, sneezing, or an increase in nasal discharge while using the product. Healthcare providers should also caution patients that sharing this container with others may increase the risk of spreading infection.

Additionally, healthcare providers should encourage patients to consult a doctor before using the product if they have any of the following conditions: heart disease, high blood pressure, diabetes, thyroid disease, or difficulty urinating due to an enlarged prostate gland.

Storage and Handling

The product is supplied in various package configurations, with specific NDC numbers available for identification. It is essential to store the product at room temperature to maintain its integrity and efficacy. No special handling requirements are necessary beyond standard storage practices.

Additional Clinical Information

The medication is administered via the nasal route. For adults and children aged 6 years and older, it is recommended to use 2 or 3 sprays in each nostril, not more frequently than every 10 to 12 hours, with a maximum of 2 doses within a 24-hour period. For children aged 2 to under 6 years, and for children aged 2 years, consultation with a doctor is advised regarding the appropriate use.

No additional information is available regarding laboratory tests, abuse potential, patient counseling, or postmarketing experience.

Drug Information (PDF)

This file contains official product information for Best Choice, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Best Choice, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.