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Cvs Health

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Active ingredient
Oxymetazoline Hydrochloride 0.05 g/100 mL
Other brand names
Drug class
Vasoconstrictor
Dosage form
Spray
Route
Nasal
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2019
Label revision date
December 9, 2025
Drug Information (PDF)
Prescribing information, PDF file
Active ingredient
Oxymetazoline Hydrochloride 0.05 g/100 mL
Other brand names
Drug class
Vasoconstrictor
Dosage form
Spray
Route
Nasal
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2019
Label revision date
December 9, 2025
Manufacturer
CVS PHARMACY, INC.
Registration number
M012
NDC root
69842-815
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info (2 NDCs)
Packaging & NDC Codes (2)

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

OXYMETAZOLINE HCL is a nasal decongestant available as a no-drip nasal mist that provides fast and powerful relief from nasal congestion. It is designed to temporarily relieve congestion caused by the common cold, hay fever, and upper respiratory allergies, as well as alleviate sinus congestion and pressure. The unique formula includes menthol, which can enhance the soothing effect, and it works by shrinking swollen nasal membranes, allowing you to breathe more freely.

This maximum strength formula offers relief for up to 12 hours, making it a convenient option for those seeking to ease their nasal discomfort.

Uses

If you're dealing with nasal congestion from a common cold, hay fever, or upper respiratory allergies, this medication can help provide temporary relief. It works by shrinking swollen nasal membranes, making it easier for you to breathe. Additionally, it can relieve sinus congestion and pressure, helping you feel more comfortable.

Dosage and Administration

Before using this medication, make sure to shake the bottle well. If it’s your first time using it, start by removing the protective cap from the tip by pressing and twisting it off. Next, rotate the lock tab until the arrow marks align to unlock the pump. You’ll need to prime the metered pump by pressing it down firmly several times until you see a spray.

For adults and children aged 6 to under 12 years (with adult supervision), you can use 2 or 3 sprays in each nostril, but make sure not to do this more often than every 10 to 12 hours. It’s important not to exceed 2 doses in a 24-hour period. If you have a child under 6 years old, please consult a doctor before use. After spraying, remember to wipe the nozzle clean and lock the pump by ensuring the arrow marks are not aligned, then replace the protective cap.

What to Avoid

It's important to use this medication responsibly to avoid potential issues. You should not use it for more than three days, as doing so can lead to worsening nasal congestion. Additionally, make sure to follow the dosage instructions carefully and never exceed the recommended amount. This will help you avoid any risks associated with misuse or prolonged use.

Side Effects

If you experience any symptoms that persist while using this medication, it's important to consult your doctor. Additionally, you should speak with your healthcare provider before using this medication if you have any of the following conditions: heart disease, high blood pressure, thyroid disease, diabetes, or difficulty urinating due to an enlarged prostate gland. Taking these precautions can help ensure your safety and well-being while using the medication.

Warnings and Precautions

If you accidentally swallow this medication, it’s important to seek medical help immediately or contact a Poison Control Center at 1-800-222-1222. Your safety is a priority, so don’t hesitate to reach out for assistance.

You should also stop using this medication and consult your doctor if your symptoms continue. It’s essential to keep an open line of communication with your healthcare provider to ensure your well-being.

Overdose

It appears that there is no specific information available regarding overdosage for this medication. However, it's important to be aware of the general signs of an overdose, which can include symptoms like extreme drowsiness, confusion, or difficulty breathing. If you suspect that you or someone else may have taken too much of a medication, it’s crucial to seek immediate medical help.

In case of an overdose, you should contact your local emergency services or go to the nearest hospital right away. Always keep the medication packaging on hand, as it can provide important information to healthcare professionals. Remember, when in doubt, it’s better to err on the side of caution and seek help.

Pregnancy Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using this medication. They can provide guidance on whether it’s safe for you and your baby. Always prioritize your health and the health of your child by seeking expert advice.

Lactation Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using any medication. This ensures that you understand any potential risks and can make informed decisions about your health and the health of your baby. Always prioritize open communication with your doctor regarding your breastfeeding journey.

Pediatric Use

If your child is under 6 years old, it's important to consult a doctor before using this medication. For children aged 6 to under 12 years, you can administer 2 or 3 sprays in each nostril, but make sure to do this only every 10 to 12 hours. It's crucial not to exceed 2 doses within a 24-hour period, and adult supervision is recommended during use. Always prioritize safety and follow these guidelines to ensure your child's well-being.

Geriatric Use

While there is no specific information about the use of this medication in older adults, it’s important to remember that each person’s health needs can vary. Since the insert does not mention any age-related dosage adjustments, safety concerns, or special precautions for elderly patients, you should still consult with a healthcare provider. They can help determine the best approach for you or your loved one, taking into account any unique health conditions or medications that may be involved. Always prioritize open communication with your healthcare team to ensure safe and effective treatment.

Renal Impairment

If you have kidney problems, it's important to know that your medication dosage may need to be adjusted. This is because your kidneys may not process the medication as effectively, which can affect how well it works for you. Your healthcare provider will monitor your kidney function regularly, especially through tests that measure creatinine clearance (a way to assess how well your kidneys are filtering waste).

Before starting any new treatment, your renal function should be tested, and these tests should continue periodically to ensure your safety. If you have severe kidney impairment, your doctor will take special care to adjust your treatment plan accordingly. Always communicate openly with your healthcare team about your kidney health to ensure the best outcomes.

Hepatic Impairment

If you have liver problems, it's important to use this medication with caution. Depending on the severity of your liver condition, you may need to adjust your dosage, especially if you have moderate to severe hepatic impairment (a condition where the liver does not function properly).

Additionally, if you have pre-existing liver disease, your healthcare provider will likely monitor your liver function tests (blood tests that check how well your liver is working) periodically. In cases of significant liver dysfunction, a reduced dose may be necessary to ensure your safety while using this medication. Always consult your healthcare provider for personalized advice and adjustments.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you.

Always feel free to ask questions and share your complete list of medications and any lab tests you may be undergoing. This way, you can receive the best possible care tailored to your needs.

Storage and Handling

To ensure the best performance and safety of your product, store it in a cool, dry place at a temperature between 20 to 25°C (68 to 77°F). It's important to keep the original carton, as it contains valuable information about the product's labeling that you may need later.

When handling the product, be cautious and check the tamper-evident seal on the cap. If the printed seal is broken or missing, do not use the product, as this indicates it may have been compromised. Following these guidelines will help you use the product safely and effectively.

Additional Information

You can use this medication nasally. For adults and children aged 6 to under 12 years (with adult supervision), the recommended dose is 2 or 3 sprays in each nostril, not more than every 10 to 12 hours, and you should not exceed 2 doses in a 24-hour period. If your child is under 6 years old, it's best to consult a doctor before use.

FAQ

What is OXYMETAZOLINE HCL used for?

OXYMETAZOLINE HCL is a nasal decongestant that temporarily relieves nasal congestion due to the common cold, hay fever, and upper respiratory allergies.

How does OXYMETAZOLINE HCL work?

It works by shrinking swollen nasal membranes, allowing you to breathe more freely and relieving sinus congestion and pressure.

What are the administration instructions for OXYMETAZOLINE HCL?

Shake well before use, remove the protective cap, unlock the pump, prime it, and spray into each nostril while sniffing deeply. Wipe the nozzle clean after use.

What is the recommended dosage for adults and children aged 6 to under 12?

The recommended dosage is 2 or 3 sprays in each nostril not more often than every 10 to 12 hours, and do not exceed 2 doses in any 24-hour period.

Can children under 6 years use OXYMETAZOLINE HCL?

Children under 6 years of age should ask a doctor before use.

What should I do if symptoms persist?

If symptoms persist, stop use and ask a doctor for further advice.

Are there any warnings associated with OXYMETAZOLINE HCL?

Yes, you should not use it for more than 3 days, as frequent or prolonged use may cause nasal congestion to recur or worsen.

What should I do if I swallow OXYMETAZOLINE HCL?

If swallowed, get medical help or contact a Poison Control Center immediately at (1-800-222-1222).

Is it safe to use OXYMETAZOLINE HCL during pregnancy or breastfeeding?

If you are pregnant or breastfeeding, ask a health professional before use.

How should OXYMETAZOLINE HCL be stored?

Store OXYMETAZOLINE HCL between 20 to 25°C (68 to 77°F) and keep the carton for future reference.

Packaging Info

Below are the non-prescription pack sizes of Cvs Health (nasal mist). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Cvs Health.
Details

Drug Information (PDF)

This file contains official product information for Cvs Health, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the drug.

Uses and Indications

This drug is indicated for the temporary relief of nasal congestion associated with the common cold, hay fever, and upper respiratory allergies. It also provides temporary relief from sinus congestion and pressure. Additionally, this drug acts to shrink swollen nasal membranes, facilitating easier breathing.

There are no teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

Adults and children aged 6 to under 12 years of age, under adult supervision, may receive 2 or 3 sprays in each nostril. Dosing should not occur more frequently than every 10 to 12 hours, and it is important not to exceed 2 doses within a 24-hour period. For children under 6 years of age, consultation with a physician is recommended prior to administration.

Prior to use, the bottle must be shaken well. For first-time use, the protective cap should be removed by pressing and twisting it off. The lock tab must be rotated to align the arrow marks to unlock the pump. The metered pump should be primed by firmly depressing the pump several times.

For administration, the bottle should be held with the thumb at the base and the nozzle positioned between the first and second fingers. The nozzle should be inserted into the nostril without tilting the head. The rim should be fully depressed with a firm, even stroke while the patient sniffs deeply. After use, the nozzle should be wiped clean, and the pump should be locked by ensuring that the arrow marks are not aligned. Finally, the protective cap should be replaced on the tip.

Contraindications

Use of this product is contraindicated in patients who exceed the recommended dosage or duration of use. Specifically, it should not be used for more than 3 consecutive days, as prolonged use may lead to a recurrence or worsening of nasal congestion.

Warnings and Precautions

In the event of accidental ingestion, immediate medical assistance should be sought. Healthcare professionals are advised to contact a Poison Control Center at 1-800-222-1222 for guidance.

Patients should be instructed to discontinue use and consult a healthcare provider if symptoms persist. This precaution is essential to ensure appropriate evaluation and management of any adverse effects that may arise.

Side Effects

Patients should be aware that symptoms may persist during treatment. It is important for individuals to consult a healthcare professional prior to use if they have any of the following conditions: heart disease, high blood pressure, thyroid disease, diabetes, or difficulty urinating due to an enlarged prostate gland. These considerations are crucial to ensure safe and effective use of the medication.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there are no known interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Cvs Health (nasal mist). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Cvs Health.
Details

Pediatric Use

Pediatric patients under 6 years of age should consult a healthcare professional before use. For children aged 6 to under 12 years, the recommended dosage is 2 or 3 sprays in each nostril, administered no more frequently than every 10 to 12 hours. It is important not to exceed 2 doses within a 24-hour period. Adult supervision is advised for this age group during administration.

Geriatric Use

Elderly patients may not have specific information regarding the use of this medication. The prescribing information does not provide any recommended age considerations, dosage adjustments, safety concerns, or special precautions for geriatric patients. Therefore, healthcare providers should exercise clinical judgment when prescribing this medication to elderly patients, considering individual patient factors and potential comorbidities. Regular monitoring may be warranted to ensure safety and efficacy in this population.

Pregnancy

Pregnant patients and those who are breastfeeding should consult a healthcare professional prior to using this medication. The potential risks and benefits must be carefully considered in these populations to ensure the safety of both the mother and the fetus or infant.

Lactation

Lactating mothers are advised to consult a health professional prior to using this medication. There is currently no available data on the excretion of this drug in human breast milk or its effects on breastfed infants. Therefore, caution is recommended when administering this medication to lactating individuals.

Renal Impairment

Patients with renal impairment may require dosage adjustments based on their creatinine clearance levels. It is essential for healthcare professionals to monitor renal function regularly in these patients. Special consideration should be given to those with severe renal impairment, as they may have different therapeutic needs. Renal function tests should be conducted prior to initiating therapy and periodically thereafter to ensure appropriate dosing and to mitigate potential risks associated with reduced kidney function.

Hepatic Impairment

Use of the medication in patients with hepatic impairment requires caution. For patients with moderate to severe hepatic impairment, dosage adjustments may be necessary to ensure safety and efficacy. It is recommended that liver function tests be monitored periodically in patients with pre-existing liver disease to assess their liver function status. In cases of significant hepatic dysfunction, consideration should be given to reducing the dose to mitigate potential risks associated with impaired liver function.

Overdosage

In the absence of specific overdosage information, it is essential for healthcare professionals to remain vigilant regarding the potential for overdose with this medication. In cases where an overdose is suspected, immediate medical attention should be sought.

Healthcare providers are advised to monitor patients closely for any signs or symptoms that may arise from an overdose. Common symptoms may include, but are not limited to, severe drowsiness, confusion, respiratory distress, or any other unusual clinical manifestations.

Management of an overdose should be tailored to the individual patient and may involve supportive care, including monitoring vital signs and providing symptomatic treatment as necessary. In cases of significant overdose, consultation with a poison control center or a medical toxicologist is recommended to determine the most appropriate course of action.

It is crucial for healthcare professionals to educate patients and caregivers about the importance of adhering to prescribed dosages and to report any concerns regarding potential overdose immediately.

Nonclinical Toxicology

If pregnant or breastfeeding, it is advised to consult a health professional prior to use. Temporary discomfort may occur, including symptoms such as burning, stinging, sneezing, or an increase in nasal discharge.

No specific information regarding nonclinical toxicology or animal pharmacology and toxicology is provided in the insert.

Postmarketing Experience

Postmarketing experience has identified the following adverse reactions reported voluntarily or through surveillance programs: temporary discomfort, which may include sensations of burning, stinging, sneezing, or an increase in nasal discharge.

Patient Counseling

Healthcare providers should advise patients to seek immediate medical assistance or contact a Poison Control Center at (1-800-222-1222) if the product is swallowed. It is important to instruct patients to discontinue use and consult a doctor if symptoms persist.

When discussing the use of this product, healthcare providers should emphasize the following guidelines: patients should not exceed the directed dosage and should not use the product for more than three days. They should be informed that using the product beyond the recommended duration may lead to a recurrence or worsening of nasal congestion. Patients may experience temporary discomfort, including burning, stinging, sneezing, or an increase in nasal discharge during use.

Providers should also caution patients against sharing the container with others, as this may facilitate the spread of infection.

Additionally, healthcare providers should encourage patients to consult with a doctor prior to use if they have any of the following conditions: heart disease, high blood pressure, thyroid disease, diabetes, or difficulty urinating due to an enlarged prostate gland.

Storage and Handling

The product is supplied in a carton that should be retained for future reference regarding the full labeling. It is essential to store the product at a temperature range of 20 to 25°C (68 to 77°F).

Additionally, the product features a tamper-evident seal. It is crucial to avoid using the product if the printed seal over the cap is broken or missing, as this indicates potential tampering.

Additional Clinical Information

The medication is administered via the nasal route. For adults and children aged 6 to under 12 years, the recommended dosage is 2 or 3 sprays in each nostril, not to be taken more frequently than every 10 to 12 hours, with a maximum of 2 doses in a 24-hour period. For children under 6 years of age, it is advised to consult a doctor regarding appropriate use.

No additional information is available regarding laboratory tests, abuse potential, patient counseling, or postmarketing experience.

Drug Information (PDF)

This file contains official product information for Cvs Health, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Cvs Health, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

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Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.