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Discount Drug Mart

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Active ingredient
Oxymetazoline Hydrochloride 0.05 g/100 mL
Other brand names
Drug class
Vasoconstrictor
Dosage form
Spray
Route
Nasal
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2019
Label revision date
September 11, 2025
Drug Information (PDF)
Prescribing information, PDF file
Active ingredient
Oxymetazoline Hydrochloride 0.05 g/100 mL
Other brand names
Drug class
Vasoconstrictor
Dosage form
Spray
Route
Nasal
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2019
Label revision date
September 11, 2025
Manufacturer
DISCOUNT DRUG MART
Registration number
M012
NDC root
53943-715
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info
Packaging & NDC Codes

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

Oxymetazoline HCl 0.05% is a nasal spray designed to provide maximum strength relief from nasal congestion. It works by temporarily relieving congestion caused by the common cold, hay fever, and other upper respiratory allergies. Additionally, it helps alleviate sinus congestion and pressure by shrinking swollen nasal membranes, allowing you to breathe more freely for up to 12 hours.

This fast-acting spray is comparable to the active ingredient found in Afrin® original, making it a powerful option for those seeking relief from cold and allergy symptoms.

Uses

If you're dealing with nasal congestion from a common cold, hay fever, or other upper respiratory allergies, this medication can help provide temporary relief. It works by shrinking swollen nasal membranes, making it easier for you to breathe. Additionally, it can relieve sinus congestion and pressure, helping you feel more comfortable.

Dosage and Administration

Before using this medication, make sure to shake the bottle well. To prepare it for use, push down on the cap while turning it counter-clockwise to remove it. Don’t forget to take off the clip located under the rim. If you’re using it for the first time, you’ll need to prime the metered pump by pressing it down firmly several times.

For adults and children aged 6 to under 12 years (with adult supervision), you can spray 2 or 3 sprays into each nostril, but make sure not to do this more often than every 10 to 12 hours. It’s important not to exceed 2 doses in a 24-hour period. If the user is a child under 6 years old, please consult a doctor for guidance. After using the spray, wipe the nozzle clean, replace the clip under the rim, and securely put the cap back on.

What to Avoid

It's important to use this medication responsibly to ensure your safety and well-being. You should not use it for more than three days, as prolonged use can lead to a worsening of nasal congestion. Always follow the directions provided and avoid using more than the recommended amount. Additionally, sharing this medication with others can increase the risk of spreading infections, so it's best to keep it for your personal use only.

Side Effects

If you experience any persistent symptoms while using this medication, it's important to stop use and consult your doctor. Additionally, you should talk to your doctor before using this medication if you have any of the following conditions: heart disease, high blood pressure, diabetes, thyroid disease, or difficulty urinating due to an enlarged prostate gland.

Being aware of these factors can help ensure your safety and the effectiveness of your treatment. Always prioritize open communication with your healthcare provider regarding your health conditions.

Warnings and Precautions

If you accidentally swallow this medication, it’s important to seek medical help immediately or contact a Poison Control Center at 1-800-222-1222. Your safety is a priority, so don’t hesitate to reach out for assistance.

You should stop using this medication and consult your doctor if your symptoms continue despite treatment. It’s essential to keep an open line of communication with your healthcare provider to ensure you receive the best care possible.

Overdose

It appears that there is no specific information available regarding overdosage for this medication. However, it's important to be aware of the general signs of an overdose, which can include symptoms like extreme drowsiness, confusion, or difficulty breathing. If you suspect an overdose, it is crucial to seek immediate medical help.

In case of an emergency, call your local emergency number or go to the nearest hospital. Always keep your medications in a safe place and follow the prescribed dosage to prevent any potential risks. If you have any concerns or questions about your medication, don’t hesitate to reach out to your healthcare provider for guidance.

Pregnancy Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using this medication. They can provide guidance on whether it’s safe for you and your baby. Always prioritize your health and the health of your child by seeking expert advice.

Lactation Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using any medication. This ensures that you understand any potential risks and can make informed decisions about your health and the health of your baby. Always prioritize open communication with your doctor regarding your breastfeeding journey.

Pediatric Use

If you have a child under 6 years old, it's important to consult a doctor before using this medication. For children aged 6 to under 12 years, you can administer 2 or 3 sprays in each nostril, but make sure to do this only every 10 to 12 hours. It's crucial not to exceed 2 doses within a 24-hour period to ensure their safety. Always supervise your child during use to help them follow these guidelines properly.

Geriatric Use

When it comes to using this medication in older adults, there is no specific information available about dosage adjustments, safety concerns, or special precautions. This means that if you or a loved one is an older adult, it’s important to consult with a healthcare provider for personalized advice. They can help determine the best approach based on individual health needs and any other medications being taken. Always prioritize open communication with your healthcare team to ensure safe and effective treatment.

Renal Impairment

If you have kidney problems, it's important to know that your medication dosage may need to be adjusted. This adjustment is based on your creatinine clearance levels, which is a measure of how well your kidneys are filtering waste from your blood. Regular monitoring of your renal function is essential, so your healthcare provider will likely perform tests before starting your treatment and continue to check your kidney function periodically.

For those with severe renal impairment, special care is required to ensure your safety and the effectiveness of your treatment. Always communicate with your healthcare provider about your kidney health, as they will guide you on the necessary steps to take.

Hepatic Impairment

If you have liver problems, it's important to know that your condition may affect how your body processes certain medications. This means that the dosage of the drug you are prescribed might need to be adjusted to ensure it is safe and effective for you.

Your healthcare provider will likely monitor your liver function tests (which are blood tests that check how well your liver is working) to keep an eye on your liver health while you are taking the medication. Special precautions will be taken when administering the drug to ensure your safety, so be sure to discuss any concerns with your doctor.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you.

Always feel free to ask questions and share your complete list of medications and any tests you might be undergoing. This way, you can avoid any potential issues and ensure the best possible care.

Storage and Handling

To ensure the best performance of your product, store it at room temperature. This helps maintain its effectiveness and safety. When handling the product, be sure to follow any specific instructions provided to avoid contamination or damage.

If you have any components that come with the product, make sure to keep them in a clean and safe environment. Proper storage and careful handling are key to ensuring that everything works as intended.

Additional Information

You will use this medication through your nose (nasal administration). If you are pregnant or breastfeeding, it's important to consult a healthcare professional before using this product. Always keep it out of reach of children. If a child accidentally swallows it, seek medical help immediately or contact a Poison Control Center at 1-800-222-1222.

FAQ

What is OXYMETAZOLINE HCL 0.05% used for?

OXYMETAZOLINE HCL 0.05% is a nasal spray that temporarily relieves nasal congestion due to the common cold, hay fever, and other upper respiratory allergies.

How should I use OXYMETAZOLINE HCL 0.05%?

Shake well before use, prime the pump, and spray 2 or 3 sprays in each nostril not more often than every 10 to 12 hours. Do not exceed 2 doses in any 24-hour period.

Are there any age restrictions for using this nasal spray?

Adults and children 6 to under 12 years of age can use it with adult supervision. For children under 6 years, consult a doctor.

What should I do if symptoms persist?

If symptoms persist, stop use and ask a doctor for further advice.

Can I use OXYMETAZOLINE HCL 0.05% if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, ask a health professional before use.

What are the storage instructions for this product?

Store OXYMETAZOLINE HCL 0.05% at room temperature.

What should I do if I accidentally swallow the nasal spray?

If swallowed, get medical help or contact a Poison Control Center right away at (1-800-222-1222).

What are the potential side effects of using this nasal spray?

Temporary discomfort such as burning, stinging, sneezing, or an increase in nasal discharge may occur.

Is there a risk of dependence or misuse with OXYMETAZOLINE HCL 0.05%?

There are no specified risks of dependence or misuse associated with this product.

What should I do if the seal over the cap is broken or missing?

Do not use the product if the printed seal over the cap is broken or missing, as it may be tampered with.

Packaging Info

Below are the non-prescription pack sizes of Discount Drug Mart (oxymetazoline hydrochloride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Discount Drug Mart.
Details

Drug Information (PDF)

This file contains official product information for Discount Drug Mart, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the specified drug.

Uses and Indications

This drug is indicated for the temporary relief of nasal congestion associated with the common cold, hay fever, and other upper respiratory allergies. It also provides temporary relief from sinus congestion and pressure. Additionally, this drug acts to shrink swollen nasal membranes, facilitating easier breathing.

There are no teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

Adults and children aged 6 to under 12 years of age, under adult supervision, may receive 2 or 3 sprays in each nostril. Dosing should not occur more frequently than every 10 to 12 hours, and it is important not to exceed 2 doses within a 24-hour period.

For children under 6 years of age, it is advised to consult a physician prior to administration.

Prior to use, the product must be shaken well. To prepare the bottle for use, push down the cap while turning it counter-clockwise to remove it. The clip located under the rim should be removed. Before the initial use, the metered pump must be primed by firmly depressing the pump several times.

For administration, the bottle should be held with the thumb at the base and the nozzle rim positioned between the first and second fingers. The nozzle should be inserted into the nostril without tilting the head. A full depression of the rim should be performed with a firm, even stroke while simultaneously sniffing deeply. After use, the nozzle must be wiped clean, and the clip should be replaced under the rim before securing the cap.

Contraindications

There are no specific contraindications identified for this product. However, the following precautions should be observed:

  • Use should not exceed the directed dosage.

  • The product should not be used for more than three consecutive days, as frequent or prolonged use may lead to a recurrence or worsening of nasal congestion.

  • The container should not be used by multiple individuals to prevent the risk of infection transmission.

Warnings and Precautions

In the event of accidental ingestion, immediate medical assistance should be sought. Healthcare professionals are advised to contact a Poison Control Center at (1-800-222-1222) without delay.

Patients should discontinue use and consult a physician if symptoms persist. Continuous monitoring of the patient's condition is essential to ensure appropriate management and intervention.

Side Effects

Patients should be aware of the potential adverse reactions associated with the use of this medication. In clinical practice, it is important to monitor for serious reactions, particularly in individuals with pre-existing conditions.

Patients are advised to stop use and consult a doctor if symptoms persist. Additionally, it is recommended that patients seek medical advice before using this medication if they have a history of heart disease, high blood pressure, diabetes, thyroid disease, or difficulty urinating due to an enlarged prostate gland.

These precautions are essential to ensure the safe use of the medication and to mitigate any risks associated with underlying health conditions.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there is no information available regarding interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Discount Drug Mart (oxymetazoline hydrochloride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Discount Drug Mart.
Details

Pediatric Use

Pediatric patients under 6 years of age should consult a healthcare professional before use. For children aged 6 to under 12 years, the recommended dosage is 2 or 3 sprays in each nostril, administered no more frequently than every 10 to 12 hours. It is important not to exceed 2 doses within a 24-hour period. Adult supervision is advised for this age group to ensure proper administration and adherence to dosing guidelines.

Geriatric Use

There is no specific information regarding the use of this medication in geriatric patients, including dosage adjustments, safety concerns, or special precautions. Healthcare providers should exercise caution when prescribing this medication to elderly patients, as individual responses may vary. It is advisable to monitor these patients closely for any adverse effects or changes in efficacy, given the lack of targeted data for this population.

Pregnancy

Pregnant patients and those who are breastfeeding should consult a healthcare professional prior to using this medication. It is important to assess the potential risks and benefits, as well as any available data regarding fetal outcomes and lactation. Healthcare providers can offer guidance tailored to individual circumstances, ensuring the safety of both the patient and the developing fetus or nursing infant.

Lactation

Lactating mothers are advised to consult a health professional prior to using this medication. There is no specific data available regarding the excretion of this medication in breast milk or its effects on breastfed infants. Therefore, caution is recommended when administering this medication to lactating individuals.

Renal Impairment

Patients with renal impairment may require dosage adjustments based on their creatinine clearance levels. It is essential for healthcare professionals to monitor renal function regularly in these patients. Special consideration should be given to those with severe renal impairment, as they may be at increased risk for adverse effects. Renal function tests should be performed prior to initiating therapy and periodically thereafter to ensure appropriate dosing and to mitigate potential risks associated with reduced kidney function.

Hepatic Impairment

Patients with hepatic impairment may experience altered metabolism of the drug, necessitating dosage adjustments to ensure safety and efficacy. It is essential to monitor liver function tests in this population to assess the degree of impairment and guide treatment decisions. Special precautions should be taken when administering the drug to patients with compromised liver function, as their response to therapy may differ from that of patients with normal liver function. Regular evaluation of liver parameters is recommended to mitigate potential risks associated with hepatic impairment.

Overdosage

In the absence of specific overdosage information, it is essential for healthcare professionals to remain vigilant and prepared for potential scenarios involving overdose.

Healthcare providers should be aware that the clinical presentation of an overdose may vary depending on the substance involved and the individual patient’s characteristics. Symptoms of overdose can range from mild to severe and may include alterations in consciousness, respiratory distress, cardiovascular instability, and gastrointestinal disturbances.

In the event of suspected overdosage, immediate medical evaluation is recommended. Healthcare professionals should assess the patient's vital signs and perform a thorough clinical examination. Supportive care should be initiated as necessary, including airway management, oxygen supplementation, and intravenous fluids.

If the specific agent involved in the overdose is known, appropriate antidotes or treatments should be administered as per established guidelines. Continuous monitoring of the patient’s condition is crucial, and further interventions may be required based on the evolving clinical picture.

It is advisable for healthcare professionals to consult local poison control centers or toxicology experts for guidance on the management of overdose cases, ensuring that the most effective and evidence-based treatment strategies are employed.

Nonclinical Toxicology

If pregnant or breastfeeding, it is advised to consult a health professional prior to use. Temporary discomfort may occur, including symptoms such as burning, stinging, sneezing, or an increase in nasal discharge.

No relevant information is available regarding carcinogenicity, mutagenicity, or impairment of fertility. Additionally, there is no pertinent data provided from animal pharmacology and toxicology studies.

Postmarketing Experience

Postmarketing experience has indicated that the use of this product may be associated with temporary discomfort, including symptoms such as burning, stinging, sneezing, or an increase in nasal discharge. These events have been reported voluntarily or identified through surveillance programs.

Patient Counseling

Healthcare providers should advise patients to seek immediate medical assistance or contact a Poison Control Center at (1-800-222-1222) if the product is swallowed. Patients should be informed to discontinue use and consult a doctor if symptoms persist.

When using this product, it is essential to instruct patients not to exceed the recommended dosage and to limit use to no more than three days. They should be cautioned that frequent or prolonged use may lead to a recurrence or worsening of nasal congestion. Patients may experience temporary discomfort, including burning, stinging, sneezing, or an increase in nasal discharge.

Healthcare providers should also emphasize that this product should not be shared among individuals, as doing so may facilitate the spread of infection.

Additionally, patients should be encouraged to consult a doctor prior to use if they have any of the following conditions: heart disease, high blood pressure, diabetes, thyroid disease, or difficulty urinating due to an enlarged prostate gland.

Storage and Handling

The product is supplied in various package configurations, with specific NDC numbers available for identification. It is essential to store the product at room temperature to maintain its integrity and efficacy. Proper handling should be observed to ensure the product remains within the recommended storage conditions.

Additional Clinical Information

The product is administered via the nasal route. Clinicians should advise patients who are pregnant or breastfeeding to consult a health professional prior to use. It is also important to instruct patients to keep the product out of reach of children and to seek immediate medical assistance or contact a Poison Control Center at (1-800-222-1222) if the product is swallowed. No further information is available regarding laboratory tests, abuse potential, or postmarketing experiences.

Drug Information (PDF)

This file contains official product information for Discount Drug Mart, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Discount Drug Mart, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.