Symptom checker
Select audience type

Switch between content for healthcare professionals (PRO) and general audience (GEN).

ADD CONDITION

items per page

Discount Drug Mart

Last content change checked dailysee data sync status

Active ingredient
Oxymetazoline Hydrochloride 0.05 g/100 mL
Other brand names
Drug class
Vasoconstrictor
Dosage form
Spray
Route
Nasal
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2019
Label revision date
September 11, 2025
Drug Information (PDF)
Prescribing information, PDF file
Active ingredient
Oxymetazoline Hydrochloride 0.05 g/100 mL
Other brand names
Drug class
Vasoconstrictor
Dosage form
Spray
Route
Nasal
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2019
Label revision date
September 11, 2025
Manufacturer
DISCOUNT DRUG MART
Registration number
M012
NDC root
53943-716
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info
Packaging & NDC Codes

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

OXYMETAZOLINE HCL 0.05% is a maximum strength nasal spray designed to temporarily relieve nasal congestion caused by common colds, hay fever, and upper respiratory allergies. It works by shrinking swollen nasal membranes, allowing you to breathe more freely. This nasal decongestant also helps alleviate sinus congestion and pressure, providing fast and powerful relief.

The spray includes menthol for added comfort and is formulated to provide a 12-hour no-drip experience, making it convenient for use throughout the day. Whether you're dealing with seasonal allergies or a cold, OXYMETAZOLINE HCL can help you feel more comfortable and breathe easier.

Uses

If you're dealing with nasal congestion from a common cold, hay fever, or upper respiratory allergies, this medication can help provide temporary relief. It works by shrinking swollen nasal membranes, making it easier for you to breathe. Additionally, it can alleviate sinus congestion and pressure, helping you feel more comfortable.

Dosage and Administration

Before using this medication, make sure to shake the bottle well. To prepare it for use, push down on the cap while turning it counter-clockwise to remove it. Don’t forget to take off the clip located under the rim. If you’re using it for the first time, you’ll need to prime the metered pump by pressing it down firmly several times until you see a spray.

For adults and children aged 6 to under 12 years, you can use 2 or 3 sprays in each nostril, but make sure not to do this more often than every 10 to 12 hours. It’s important not to exceed 2 doses in a 24-hour period. If the user is a child under 6 years old, please consult a doctor before use. After spraying, remember to wipe the nozzle clean, replace the clip under the rim, and securely put the cap back on.

What to Avoid

It's important to use this medication responsibly to avoid potential issues. You should not use it for more than three days, and always follow the directions provided. Using more than directed can lead to problems, such as worsening nasal congestion. Additionally, sharing this medication with others can increase the risk of spreading infections, so it's best to keep it for your personal use only.

Remember, frequent or prolonged use can lead to complications, so be mindful of how you use this product. If you have any concerns or questions, don't hesitate to reach out to a healthcare professional for guidance.

Side Effects

If you experience any persistent symptoms while using this medication, it's important to stop use and consult your doctor. Additionally, you should talk to your doctor before using this medication if you have any of the following conditions: heart disease, high blood pressure, thyroid disease, diabetes, or difficulty urinating due to an enlarged prostate gland.

Being aware of these factors can help ensure your safety and the effectiveness of your treatment. Always prioritize open communication with your healthcare provider regarding your health conditions.

Warnings and Precautions

If you accidentally swallow this medication, it’s important to seek medical help immediately or contact a Poison Control Center at 1-800-222-1222. Your safety is a priority, so don’t hesitate to reach out for assistance.

You should stop using this medication and consult your doctor if your symptoms continue despite treatment. It’s essential to keep an open line of communication with your healthcare provider to ensure you are receiving the best care possible.

Overdose

It appears that there is no specific information available regarding overdosage for this medication. However, it's always important to be aware of the signs of an overdose, which can include symptoms like extreme drowsiness, confusion, or difficulty breathing. If you suspect that you or someone else may have taken too much of a medication, it’s crucial to seek immediate medical help.

In case of an overdose, contact your local emergency services or go to the nearest hospital. Having the medication packaging or information on hand can help healthcare professionals provide the best care. Always remember that when it comes to medications, it's better to be safe and get help if you have any concerns.

Pregnancy Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using this medication. They can provide guidance on whether it’s safe for you and your baby. Always prioritize your health and the health of your child by seeking expert advice.

Lactation Use

If you are pregnant or breastfeeding, it’s important to consult with a healthcare professional before using any medication. This ensures that you understand any potential risks and can make informed decisions about your health and the health of your baby. Always prioritize open communication with your doctor regarding your breastfeeding journey.

Pediatric Use

If you have a child under 6 years old, it's important to consult a doctor before using this medication. For children aged 6 to under 12 years, you can administer 2 or 3 sprays in each nostril, but make sure to do this only every 10 to 12 hours. It's crucial not to exceed 2 doses within a 24-hour period to ensure their safety. Always supervise your child during use to help them follow these guidelines properly.

Geriatric Use

While there is no specific information available about the use of this medication in older adults, it’s important to approach any new treatment with caution. Since older adults may have different health needs and may be taking multiple medications, it’s always a good idea to consult with a healthcare provider before starting any new medication. They can help ensure that the treatment is safe and appropriate for your individual health situation.

If you or a loved one is an older adult, be sure to discuss any concerns about potential side effects or interactions with other medications you may be taking. Your healthcare provider can provide guidance tailored to your specific needs.

Renal Impairment

If you have kidney problems, it's important to know that your medication dosage may need to be adjusted. This is because your renal function, which is how well your kidneys are working, can affect how your body processes certain medications. Your healthcare provider will monitor your renal function regularly, especially through tests that measure creatinine clearance (a test that estimates how well your kidneys filter waste).

Before starting any new treatment, your renal function should be tested, and these tests will continue periodically to ensure your safety. If you have moderate to severe renal impairment, you may require a reduced dose of your medication. Always discuss your kidney health with your doctor to ensure you receive the appropriate care.

Hepatic Impairment

If you have liver problems, it's important to know that your dosage of this medication may need to be adjusted. This is because your liver's ability to process the drug can be affected. Additionally, your healthcare provider will likely recommend special monitoring of your liver function tests (which check how well your liver is working) to ensure your safety while using this medication.

Caution is advised when taking this drug if you have liver impairment, as it may change how your body metabolizes (processes) the medication. Always discuss your liver health with your doctor to ensure you receive the appropriate care and adjustments needed for your treatment.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you.

Always discuss your full list of medications, including over-the-counter drugs and supplements, as well as any upcoming lab tests. This way, you can avoid any potential issues and receive the best care possible.

Storage and Handling

To ensure the best performance and safety of your product, it is important to store it at room temperature. This helps maintain its effectiveness and integrity. When handling the product, always do so with clean hands and in a clean environment to avoid contamination.

If you have any specific components that come with the product, make sure to follow any additional instructions provided for their use or storage. Proper disposal of any unused or expired items should also be done according to local regulations to ensure safety.

Additional Information

You will use this medication through your nose (nasal administration). If you are pregnant or breastfeeding, it's important to consult a healthcare professional before using this product. Always keep it out of reach of children. If a child accidentally swallows it, seek medical help immediately or contact a Poison Control Center at 1-800-222-1222.

FAQ

What is OXYMETAZOLINE HCL 0.05% used for?

OXYMETAZOLINE HCL 0.05% is a nasal decongestant that temporarily relieves nasal congestion due to common cold, hay fever, and upper respiratory allergies.

How should I use OXYMETAZOLINE HCL 0.05%?

Shake well before use, prime the pump, and spray 2 or 3 sprays in each nostril every 10 to 12 hours, not exceeding 2 doses in 24 hours.

Are there any age restrictions for using this nasal spray?

Adults and children 6 to under 12 years can use it with adult supervision, while children under 6 years should ask a doctor.

What should I do if symptoms persist?

Stop use and ask a doctor if symptoms persist.

Can I use OXYMETAZOLINE HCL 0.05% if I am pregnant or breastfeeding?

If pregnant or breastfeeding, you should ask a health professional before use.

What are the storage instructions for this product?

Store OXYMETAZOLINE HCL 0.05% at room temperature.

What should I do if I accidentally swallow the spray?

If swallowed, get medical help or contact a Poison Control Center right away at (1-800-222-1222).

What are the potential side effects of using this nasal spray?

Temporary discomfort such as burning, stinging, sneezing, or increased nasal discharge may occur.

Is there a risk of dependence or abuse with OXYMETAZOLINE HCL 0.05%?

There are no specified concerns regarding dependence, but frequent or prolonged use may cause nasal congestion to recur or worsen.

Packaging Info

Below are the non-prescription pack sizes of Discount Drug Mart (oxymetazoline hydrochloride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Discount Drug Mart.
Details

Drug Information (PDF)

This file contains official product information for Discount Drug Mart, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the specified drug.

Uses and Indications

This drug is indicated for the temporary relief of nasal congestion associated with the common cold, hay fever, and upper respiratory allergies. It also provides temporary relief from sinus congestion and pressure. Additionally, this drug acts to shrink swollen nasal membranes, facilitating easier breathing.

There are no teratogenic or nonteratogenic effects associated with this drug.

Dosage and Administration

Adults and children aged 6 to under 12 years, under adult supervision, may receive 2 or 3 sprays in each nostril, not to be administered more frequently than every 10 to 12 hours. The total dosage must not exceed 2 doses within a 24-hour period.

For children under 6 years of age, it is advised to consult a physician prior to administration.

Prior to use, the product must be shaken well. To prepare the bottle for use, push down the cap while turning it counter-clockwise to remove it. Remove the clip located under the rim. Before the initial use, the metered pump should be primed by firmly depressing the pump several times.

For administration, the bottle should be held with the thumb at the base and the nozzle positioned between the first and second fingers. The nozzle should be inserted into the nostril without tilting the head. The rim should be fully depressed with a firm, even stroke while the patient sniffs deeply. After use, the nozzle must be wiped clean, the clip should be replaced under the rim, and the cap secured.

Contraindications

There are no specific contraindications identified for this product. However, it is important to adhere to the following guidelines to ensure safe use:

  • Do not exceed the recommended dosage or duration of use, which is limited to a maximum of 3 days. Prolonged use may lead to a recurrence or worsening of nasal congestion.

  • This product should not be used by more than one individual from the same container to prevent the potential spread of infection.

Warnings and Precautions

In the event of accidental ingestion, immediate medical assistance should be sought. Healthcare professionals are advised to contact a Poison Control Center at (1-800-222-1222) for guidance.

Patients should discontinue use and consult a physician if symptoms persist. Continuous monitoring of the patient's condition is recommended to ensure appropriate management and intervention if necessary.

Side Effects

Patients should be aware of the potential adverse reactions associated with the use of this medication. In the event that symptoms persist, it is advised to stop use and consult a healthcare professional.

Before initiating treatment, patients with certain pre-existing conditions should seek medical advice. Specifically, individuals with heart disease, high blood pressure, thyroid disease, diabetes, or those experiencing difficulty urinating due to an enlarged prostate gland should consult a doctor prior to use.

These precautions are essential to ensure the safe and effective use of the medication, minimizing the risk of serious adverse reactions.

Drug Interactions

There are currently no documented drug interactions associated with the use of this medication. Additionally, there is no information available regarding interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Discount Drug Mart (oxymetazoline hydrochloride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Discount Drug Mart.
Details

Pediatric Use

Pediatric patients under 6 years of age should consult a healthcare professional before use. For children aged 6 to under 12 years, the recommended dosage is 2 or 3 sprays in each nostril, administered no more frequently than every 10 to 12 hours. It is important not to exceed 2 doses within a 24-hour period. Adult supervision is advised for this age group to ensure proper administration and adherence to dosing guidelines.

Geriatric Use

There is no specific information regarding the use of this medication in geriatric patients, including dosage adjustments, safety concerns, or special precautions. Healthcare providers should exercise caution when prescribing this medication to elderly patients, as individual responses may vary. It is advisable to monitor these patients closely for any adverse effects or changes in efficacy.

Pregnancy

Pregnant patients and those who are breastfeeding should consult a healthcare professional prior to using this medication. It is essential to evaluate the potential risks and benefits associated with its use during pregnancy and lactation.

Lactation

Lactating mothers are advised to consult a health professional prior to using this medication. There is currently no available data regarding the excretion of this medication in human breast milk or its effects on breastfed infants. Therefore, caution is recommended when administering this medication to lactating individuals.

Renal Impairment

Patients with renal impairment may require dosage adjustments based on their level of renal function. It is essential for healthcare professionals to monitor renal function regularly in these patients. Adjustments to the dosage should be guided by creatinine clearance levels, with reduced doses being necessary for those with moderate to severe renal impairment. Additionally, renal function tests should be conducted prior to initiating therapy and periodically thereafter to ensure appropriate management of the patient's condition.

Hepatic Impairment

Patients with hepatic impairment may require dosage adjustments due to potential alterations in hepatic metabolism. It is essential to exercise caution when administering the drug to this population. Special monitoring of liver function tests is recommended to ensure patient safety and to assess the need for any further adjustments in therapy. Regular evaluation of liver function will help in managing the risks associated with compromised liver function effectively.

Overdosage

In the absence of specific overdosage information, it is essential for healthcare professionals to remain vigilant and prepared for potential scenarios involving overdose.

Healthcare providers should be aware that the clinical presentation of an overdose may vary significantly depending on the substance involved and the individual patient’s characteristics. Symptoms may include, but are not limited to, altered mental status, cardiovascular instability, respiratory distress, and gastrointestinal disturbances.

In the event of suspected overdosage, immediate assessment of the patient's condition is critical. Recommended actions include:

  1. Assessment and Monitoring: Continuous monitoring of vital signs and neurological status is imperative. Establishing intravenous access may be necessary for fluid resuscitation or medication administration.

  2. Supportive Care: Provide supportive care tailored to the symptoms exhibited by the patient. This may involve airway management, supplemental oxygen, or other interventions as clinically indicated.

  3. Decontamination: If the overdose is recent and the patient is alert and able to protect their airway, activated charcoal may be administered to limit further absorption of the substance.

  4. Specific Antidotes: If applicable, the use of specific antidotes should be considered based on the substance involved in the overdose.

  5. Consultation with Poison Control: Engaging with a poison control center can provide valuable guidance on the management of the overdose and recommendations for further treatment.

  6. Hospitalization: Depending on the severity of the overdose and the patient's response to initial management, hospitalization may be warranted for further observation and treatment.

Healthcare professionals are encouraged to familiarize themselves with the specific management protocols for the substances they encounter and to maintain an up-to-date knowledge of potential overdose presentations and interventions.

Nonclinical Toxicology

If pregnant or breast-feeding, it is advised to consult a health professional prior to use. Temporary discomfort may occur, including symptoms such as burning, stinging, sneezing, or an increase in nasal discharge. No relevant information is available regarding nonclinical toxicology or animal pharmacology and toxicology.

Postmarketing Experience

Postmarketing experience has indicated that the use of this product may be associated with temporary discomfort, including symptoms such as burning, stinging, sneezing, or an increase in nasal discharge. These events have been reported voluntarily or identified through surveillance programs.

Patient Counseling

Healthcare providers should advise patients to seek immediate medical assistance or contact a Poison Control Center at (1-800-222-1222) if the product is swallowed. Patients should be informed to discontinue use and consult a doctor if symptoms persist.

When using this product, it is essential to instruct patients not to exceed the recommended dosage and to limit use to no more than three days. They should be cautioned that frequent or prolonged use may lead to a recurrence or worsening of nasal congestion. Patients may experience temporary discomfort, including burning, stinging, sneezing, or an increase in nasal discharge.

Healthcare providers should also emphasize that the use of this container by more than one person may increase the risk of spreading infection.

Before initiating treatment, patients should be encouraged to consult with their healthcare provider if they have any of the following conditions: heart disease, high blood pressure, thyroid disease, diabetes, or difficulty urinating due to an enlarged prostate gland.

Storage and Handling

The product is supplied in various package configurations, with specific NDC numbers available for identification. It is essential to store the product at room temperature to maintain its integrity and efficacy. No special handling requirements are necessary beyond standard storage practices.

Additional Clinical Information

The route of administration for the medication is nasal. Clinicians should advise patients who are pregnant or breastfeeding to consult a health professional prior to use. It is also important to instruct patients to keep the medication out of reach of children. In the event of accidental ingestion, patients should seek medical assistance or contact a Poison Control Center immediately at (1-800-222-1222). No further information is available regarding laboratory tests, abuse potential, or postmarketing experience.

Drug Information (PDF)

This file contains official product information for Discount Drug Mart, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Discount Drug Mart, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.