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Pamabrom
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- Active ingredient
- Pamabrom 50 mg
- Reference brand
- Diurex
- Dosage forms
- Capsule, Liquid Filled
- Tablet
- Tablet, Film Coated
- Route
- Oral
- Prescription status
- OTC (over the counter)
- Marketed in the U.S.
- Since 1995
- Label revision date
- January 27, 2026
- Pregnancy
- See Pregnancy Use Section
- Lactation
- See Lactation Use Section
- Active ingredient
- Pamabrom 50 mg
- Reference brand
- Diurex
- Dosage forms
- Capsule, Liquid Filled
- Tablet
- Tablet, Film Coated
- Route
- Oral
- Prescription status
- OTC (over the counter)
- CSA schedule
- Not a scheduled drug
- Marketed in the U.S.
- Since 1995
- Label revision date
- January 27, 2026
- Pregnancy
- See Pregnancy Use Section
- Lactation
- See Lactation Use Section
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Drug Overview
Pamabrom is a diuretic (a type of medication that helps the body eliminate excess water) used for the temporary relief of symptoms such as bloating, water-weight gain, swelling, and a full feeling that can occur during the premenstrual and menstrual periods. It is available in various forms, including capsules and tablets.
This medication works by promoting the excretion of water from the body, which can help alleviate discomfort associated with water retention. If you experience these symptoms, Pamabrom may provide you with the relief you need during your menstrual cycle.
Uses
You can use this medication for the temporary relief of water weight gain, bloating, swelling, and the full feeling that often occurs during your premenstrual and menstrual periods. It is designed to help alleviate these uncomfortable symptoms, making you feel more at ease during that time of the month.
This medication is available in various forms, including capsules and tablets, and is intended for short-term use to address these specific issues. There are no known teratogenic effects (which means it does not cause birth defects) associated with this medication.
Dosage and Administration
You should take one softgel capsule or one pill after breakfast with a full glass of water. If needed, you can repeat the dose every 6 hours, but do not exceed four softgels or pills in a 24-hour period. It’s best to start taking the medication 5 or 6 days before your period begins and continue until you feel relief or until your period ends.
Make sure to drink 6 to 8 glasses of water daily while using this medication. This product is intended for normally healthy adults only, and if you are under 18 years of age, you should use it only as directed by a doctor. Always follow the recommended dosage and consult a healthcare professional if you have any questions.
What to Avoid
You should avoid using these products if you have ever had an allergic reaction to any of their ingredients. Additionally, keep them out of reach of children. If symptoms persist for more than ten consecutive days, stop use and consult a doctor. In case of overdose, seek medical help or contact a Poison Control Center immediately.
Side Effects
You may experience some warnings when using these products. It's important to consult a doctor or pharmacist before use if you are taking any other medications. If your symptoms last more than ten consecutive days, you should stop using the product and seek medical advice.
Additionally, if you have a history of allergic reactions to any of the ingredients in these products, you should avoid using them. There are no specific common or serious side effects listed for these medications, but always stay informed and cautious when trying new treatments.
Warnings and Precautions
Before using any of these products, ask your doctor or pharmacist if you are taking other medications, especially if you are pregnant or breastfeeding.
If you experience symptoms that last more than ten consecutive days, stop using the product and consult your doctor.
In case of an overdose, seek emergency medical help or contact a Poison Control Center immediately, as prompt attention is crucial for both adults and children.
Do not use these products if you have ever had an allergic reaction to any of their ingredients.
Overdose
If you take too much of a medication, it’s important to know what to do. For example, with Midol Bloat Relief, if you suspect an overdose, you should seek medical help or contact a Poison Control Center immediately. Signs of an overdose can vary, but it’s crucial to act quickly if you feel unwell after taking more than the recommended dose.
Currently, there is no specific overdosage information available for Pamabrom, Right Remedies Maximum Strength Diuretic, Diurex, or Pamprin. Always follow the dosage instructions on the label and consult a healthcare professional if you have any concerns.
Pregnancy Use
If you are pregnant or breastfeeding, it is important to consult a healthcare professional before using any of the following products: Pamabrom (available in capsule and liquid-filled forms), Diurex (tablet and film-coated), Pamprin (tablet and film-coated), and Midol Bloat Relief (tablet). This precaution helps ensure the safety of both you and your baby, as some ingredients may not be suitable during pregnancy or lactation. Always prioritize your health and seek guidance from a qualified provider.
Lactation Use
If you are breastfeeding, it is important to consult with a healthcare professional before using any medications, including Pamabrom, Pamprin, or Midol Bloat Relief. This is to ensure that any ingredients in these products are safe for you and your baby, as some substances can be excreted in breast milk (pass into breast milk) and potentially affect your infant. Always prioritize your health and your baby's well-being by seeking professional advice.
Pediatric Use
When considering the use of Pamabrom, Pamprin, or Midol Bloat Relief for children, it's important to follow specific guidelines. For Pamabrom, children under 18 years should only use it if directed by a doctor. For both Pamprin and Midol Bloat Relief, you should consult a doctor before giving these medications to children under 12 years. Always prioritize professional medical advice to ensure the safety and well-being of your child.
Geriatric Use
You may not find specific recommendations or precautions for older adults regarding the use of Pamabrom, Pamprin, or Midol Bloat Relief. These medications do not have detailed guidelines for dosage adjustments or safety concerns tailored to elderly patients.
As always, it's important to consult with your healthcare provider before starting any new medication, especially if you have underlying health conditions or are taking other medications. They can help ensure that the treatment is safe and appropriate for your individual needs.
Renal Impairment
If you have kidney issues, it's important to be aware that certain medications may require dosage adjustments. For example, both Pamabrom and Pamprin suggest that you may need a lower dose if you have reduced kidney function, particularly if your creatinine clearance is less than 30 mL/min. Regular monitoring of your renal function is also recommended, especially before starting treatment and periodically thereafter.
While some products, like Right Remedies Maximum Strength Diuretic, Diurex, and Midol Bloat Relief, do not provide specific guidance on renal impairment, it's always best to consult with your healthcare provider about any medications you are taking. They can help ensure that your treatment is safe and effective based on your kidney health.
Hepatic Impairment
You may be wondering about the use of certain medications if you have liver issues. Currently, there is no specific information available regarding dosage adjustments, special monitoring, or precautions for patients with liver problems for the following products: Pamabrom, Right Remedies Maximum Strength Diuretic, Diurex, Pamprin, and Midol Bloat Relief. This means that these medications do not have established guidelines for use in individuals with hepatic (liver) impairment.
If you have liver concerns, it's always best to consult with your healthcare provider before starting any new medication to ensure it is safe for you.
Drug Interactions
When using Pamabrom, Pamprin, or Midol Bloat Relief, there are currently no known interactions with other medications or laboratory tests. This means that these products are generally considered safe to use alongside other treatments, but it's still important to talk to your healthcare provider about all the medications and supplements you are taking. This helps ensure your safety and the effectiveness of your treatments, as your provider can give you personalized advice based on your health history. Always prioritize open communication with your healthcare team!
Storage and Handling
To ensure the effectiveness of your diuretic products, store them at room temperature, ideally between 20°C and 25°C (68°F to 77°F). Keep the containers tightly closed and protect them from light, heat, and moisture. If you notice that the safety seal under the cap is broken, do not use the product. After opening, it's best to discard any unused portions to maintain safety and efficacy.
For disposal, follow local guidelines for medication disposal, which may include returning unused products to a pharmacy or participating in a take-back program. Always ensure that medications are kept out of reach of children.
FAQ
What is Pamabrom used for?
Pamabrom is used for the relief of temporary water weight gain, bloating, swelling, and the full feeling associated with premenstrual and menstrual periods.
How should I take Pamabrom?
You should take one softgel capsule after breakfast with a full glass of water. The dose may be repeated after 6 hours, not to exceed four softgel capsules per day.
When should I start taking Pamabrom?
Start taking Pamabrom 5 or 6 days before the onset of your period and continue until you obtain the desired relief or until the end of your period.
Are there any age restrictions for using Pamabrom?
Pamabrom is for use by normally healthy adults only. Persons under 18 years of age should use it only as directed by a doctor.
What should I do if my symptoms last more than ten days?
You should stop using Pamabrom and ask a doctor if your symptoms last for more than ten consecutive days.
Can I take Pamabrom if I am pregnant or breastfeeding?
If you are pregnant or breastfeeding, you should ask a health professional before using Pamabrom.
What should I do in case of an overdose?
In case of overdose, get medical help or contact a Poison Control Center right away.
Is there any specific information for patients with kidney problems?
Yes, dosage adjustments may be necessary for patients with reduced renal function, and renal function tests should be monitored regularly.
What should I do if I am taking other medications?
You should ask a doctor or pharmacist before using Pamabrom if you are taking any other medication.
What is the primary use of this diuretic?
This diuretic is used for the relief of temporary water weight gain, bloating, swelling, and the full feeling associated with premenstrual and menstrual periods.
How should I take this medication?
Adults should take one softgel after breakfast with a full glass of water. The dose may be repeated after 6 hours, not to exceed four softgels in 24 hours.
Are there any warnings I should be aware of?
Yes, you should ask a doctor or pharmacist before use if you are taking any other medication, and stop use if symptoms last for more than ten consecutive days.
What is the active ingredient in DIUREX MAX?
The active ingredient in DIUREX MAX is pamabrom, with a dosage of 50 mg.
What are common side effects of DIUREX MAX?
Common side effects include nausea, vomiting, diarrhea, abdominal pain, headache, and dizziness.
What serious side effects should I be aware of?
Serious side effects may include allergic reactions such as rash, itching, swelling, severe dizziness, and trouble breathing.
Is DIUREX MAX safe to use during pregnancy?
Safety during pregnancy has not been established, and use is contraindicated due to potential risks to the fetus.
What should I do if I experience severe allergic reactions?
If you experience severe allergic reactions, seek emergency medical help immediately.
How should I store DIUREX MAX?
Store DIUREX MAX at room temperature, between 20°C to 25°C (68°F to 77°F), protect it from light, and keep the container tightly closed.
What is Midol® Bloat Relief used for?
Midol® Bloat Relief is used for the temporary relief of bloating, water-weight gain, swelling, and the full feeling associated with premenstrual and menstrual periods.
What is the recommended dosage for adults and children over 12?
Adults and children 12 years and older should take 1 caplet with water every 6 hours as needed, not exceeding 4 caplets per day.
What should I do if I am pregnant or breastfeeding?
If you are pregnant or breastfeeding, you should ask a health professional before using Midol® Bloat Relief.
What should I do in case of an overdose?
In case of overdose, you should get medical help or contact a Poison Control Center right away.
How should I store Midol® Bloat Relief?
Store Midol® Bloat Relief between 20°-25°C (68°-77°F).
Uses and Indications
This drug is indicated for the relief of temporary water weight gain, bloating, swelling, and the full feeling associated with the premenstrual and menstrual periods.
Limitations of Use
No teratogenic or nonteratogenic effects have been mentioned for this drug.
Dosage and Administration
Adults and children 12 years and older are advised to take one (1) softgel capsule or caplet after breakfast with a full glass of water. The dose may be repeated every 6 hours as needed, not to exceed four (4) softgels or caplets in a 24-hour period. It is recommended to start taking the medication 5 to 6 days before the anticipated onset of the menstrual period and to continue until desired relief is obtained or until the end of the period.
For optimal hydration, it is suggested to drink 6 to 8 glasses of water daily while using this medication. This product is intended for use by normally healthy adults only. Individuals under 18 years of age should use this medication only as directed by a healthcare professional.
Patients are cautioned not to exceed the recommended dosage. For children under 12 years of age, consultation with a doctor is advised prior to use.
Contraindications
Use is contraindicated in individuals who have a known allergy to this product or any of its ingredients. Additionally, it is advised to stop use and consult a healthcare professional if symptoms persist for more than ten consecutive days. Products should be kept out of reach of children, and in the event of an overdose, immediate medical assistance or contact with a Poison Control Center is recommended.
Warnings and Precautions
Warnings
Ask a doctor or pharmacist before use if taking any other medications.
Do not use if there has been a previous allergic reaction to this product or any of its ingredients.
If pregnant or breastfeeding, consult a health professional before use.
Get Emergency Medical Help
In case of overdose, seek medical help or contact a Poison Control Center immediately. Prompt medical attention is critical for both adults and children, even if no signs or symptoms are noticed.
Stop Taking and Call Your Doctor
Stop use and consult a doctor if symptoms persist for more than ten consecutive days.
Side Effects
Patients using the products listed may experience various adverse reactions, although specific side effects are not extensively documented across all labels.
Warnings
Patients are advised to consult a doctor or pharmacist before use if they are taking any other medications.
It is recommended to stop use and seek medical advice if symptoms persist for more than ten consecutive days.
Pregnant or breastfeeding patients should consult a healthcare professional prior to use.
Individuals with a history of allergic reactions to any of the ingredients in these products should avoid use.
Common Adverse Reactions
No common adverse reactions have been reported for the products reviewed.
Less Common Adverse Reactions
No less common adverse reactions have been documented.
Rare Adverse Reactions
No rare adverse reactions have been identified.
Serious Side Effects
No serious side effects have been reported.
Allergic Reactions
Specific allergic reactions have not been detailed; however, patients should discontinue use if they experience any allergic symptoms.
Postmarketing Experience
There is no postmarketing experience data available for these products.
Additional Notes
No additional adverse reactions or important notes have been provided in the reviewed labels.
Drug Interactions
There are no documented drug interactions associated with Pamabrom, Pamprin, or Midol Bloat Relief. Each of these products does not provide information regarding interactions with other drugs or laboratory tests. Therefore, healthcare professionals may consider these medications to have a low potential for drug interaction risks based on the available data.
Pediatric Use
Persons under 18 years of age should use Pamabrom only as directed by a doctor. For Pamprin and Midol Bloat Relief, it is advised that children under 12 years consult a doctor prior to use.
Geriatric Use
There are no specific recommendations or considerations for geriatric patients regarding the use of Pamabrom, Pamprin, or Midol Bloat Relief. The available drug inserts do not provide information on dosage adjustments, safety concerns, or special precautions for elderly patients. Healthcare professionals should exercise clinical judgment when prescribing these medications to geriatric patients, considering individual health status and potential comorbidities. Regular monitoring may be warranted to ensure safety and efficacy in this population.
Pregnancy
Pregnant patients and those who are breastfeeding should consult a healthcare professional before using products containing Pamabrom, Diurex, Pamprin, or Midol Bloat Relief. There is limited data on the safety of these medications during pregnancy, and potential risks to fetal outcomes have not been fully established. Therefore, it is essential for healthcare providers to evaluate the benefits and risks on a case-by-case basis before recommending these products to pregnant patients.
Lactation
Lactating mothers are advised to consult a healthcare professional before using products containing Pamabrom, Pamprin, or Midol Bloat Relief. There is limited data on the excretion of these substances in breast milk and their potential effects on breastfed infants. Therefore, caution is recommended when considering the use of these medications during lactation.
Renal Impairment
Patients with renal impairment may require dosage adjustments for certain medications. Specifically, for products such as Pamabrom and Pamprin, it is recommended that renal function be monitored regularly, particularly in individuals with known kidney issues.
For patients with a creatinine clearance of less than 30 mL/min, a reduced dose may be necessary. Additionally, it is advised that renal function tests be conducted prior to initiating therapy and periodically thereafter to ensure safe and effective use of these medications.
While some products, such as Right Remedies Maximum Strength Diuretic, Diurex, and Midol Bloat Relief, do not provide specific information regarding renal impairment, it remains essential for healthcare providers to exercise caution and consider the renal status of patients when prescribing these medications.
Hepatic Impairment
Patients with hepatic impairment have not been specifically studied for the medications listed, including Pamabrom, Right Remedies Maximum Strength Diuretic, Diurex, Pamprin, and Midol Bloat Relief. Consequently, there is no available information regarding dosage adjustments, special monitoring, or precautions for this patient population. It is recommended that healthcare providers exercise caution and consider individual patient factors when prescribing these medications to patients with liver problems, as the lack of data may necessitate closer monitoring for potential adverse effects.
Overdosage
In the event of an overdose, it is crucial to seek immediate medical assistance or contact a Poison Control Center. While specific overdosage information is not provided for several products, including Pamabrom, Right Remedies Maximum Strength Diuretic, Diurex, and Pamprin, it is important to remain vigilant for any potential symptoms that may arise.
For Midol Bloat Relief, individuals should be aware that an overdose may necessitate urgent medical intervention. Monitoring for symptoms associated with overdose is recommended, although specific symptoms are not detailed in the available information.
In summary, due to the lack of detailed overdosage information for most products, prompt medical evaluation is advised in cases of suspected overdose, ensuring that appropriate care is administered.
Nonclinical Toxicology
Teratogenicity
No information regarding teratogenic effects is available for Pamabrom, Pamprin, or Midol Bloat Relief.
Carcinogenesis, Mutagenesis, Impairment of Fertility
There is no information provided on carcinogenicity, mutagenicity, or impairment of fertility for any of the products, including Pamabrom, Pamprin, and Midol Bloat Relief.
Animal Toxicology
No data on animal pharmacology and toxicology is available for the products listed.
Storage and Handling
Pamabrom is supplied in blue transparent, oval-shaped softgel capsules filled with a clear to pale blue liquid. The capsules are packaged in a bottle with a safety seal under the cap. It is important to not use the product if the seal appears broken.
Right Remedies Maximum Strength Diuretic is available in capsule and liquid-filled forms. It should be stored at room temperature between 20°–25°C (68°–77°F) and protected from light, heat, and moisture.
Pamprin is provided in film-coated tablet form. It should be stored at room temperature, specifically between 20°C to 25°C (68°F to 77°F). The container must be kept tightly closed, and the product should be discarded after opening to ensure safety and efficacy.
Midol Bloat Relief is supplied in tablet form and should also be stored at a temperature range of 20°-25°C (68°-77°F).
All products should be handled with care to maintain their integrity and effectiveness.
Product Labels
The table below lists all over-the-counter labels containing pamabrom. Use it to compare dosage forms, strengths, and uses across products.
More Details | |||||
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Kobayashi Healthcare International, Inc. | Tablet, Film Coated | Oral | 50 mg | 1995 | |
Indications
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Kobayashi Healthcare International, Inc. | Tablet, Film Coated | Oral | 50 mg | 2001 | |
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Bayer HealthCare LLC. | Tablet | Oral | 50 mg | 2021 | |
Indications
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Softgel Healthcare Pvt Ltd | Capsule, Liquid Filled | Oral | 50 mg | 2024 | |
Indications
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Focus Consumer Healthcare, LLC | Tablet, Film Coated | Oral | 50 mg | 2025 | |
Indications
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Strive Pharmaceuticals Inc. | Capsule, Liquid Filled | Oral | 50 mg | 2025 | |
Indications
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