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Panacur C Canine
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- Active ingredient
- Fenbendazole 222 mg/1 g
- Other brand names
- Defendazole (by Norbrook Laboratories Limited)
- Fenbendazole (by Amgis Lifescience Limited)
- Fenbendazole (by Letco Medical, Llc)
- Fenbenpro Purity and Precision Fenbendazole (by Hubihol, Uab)
- Fenbenpro Purity and Precision Fenbendazole (by Hubihol, Uab)
- Panacur (by Merck Sharp & Dohme Corp.)
- Panacur (by Merck Sharp & Dohme Corp.)
- Panacur (by Merck Sharp & Dohme Corp.)
- Panacur (by Merck Sharp & Dohme Corp.)
- Safe-Guard (by Merck Sharp & Dohme Corp.)
- Safe-Guard (by Merck Sharp & Dohme Corp.)
- Safe-Guard (by Merck Sharp & Dohme Corp.)
- Safe-Guard (by Merck Sharp & Dohme Corp.)
- Safe-Guard (by Merck Sharp & Dohme Corp.)
- Safe-Guard Aquasol (by Merck Sharp & Dohme Corp.)
- View full label-group details →
- Dosage form
- Granule
- Route
- Oral
- Prescription status
- Animal
- Pregnancy
- See Pregnancy Use Section
- Lactation
- See Lactation Use Section
- Marketed in the U.S.
- Since 1979
- Label revision date
- November 14, 2024
- Veterinary Document
- Prescribing information, PDF file
- Active ingredient
- Fenbendazole 222 mg/1 g
- Other brand names
- Defendazole (by Norbrook Laboratories Limited)
- Fenbendazole (by Amgis Lifescience Limited)
- Fenbendazole (by Letco Medical, Llc)
- Fenbenpro Purity and Precision Fenbendazole (by Hubihol, Uab)
- Fenbenpro Purity and Precision Fenbendazole (by Hubihol, Uab)
- Panacur (by Merck Sharp & Dohme Corp.)
- Panacur (by Merck Sharp & Dohme Corp.)
- Panacur (by Merck Sharp & Dohme Corp.)
- Panacur (by Merck Sharp & Dohme Corp.)
- Safe-Guard (by Merck Sharp & Dohme Corp.)
- Safe-Guard (by Merck Sharp & Dohme Corp.)
- Safe-Guard (by Merck Sharp & Dohme Corp.)
- Safe-Guard (by Merck Sharp & Dohme Corp.)
- Safe-Guard (by Merck Sharp & Dohme Corp.)
- Safe-Guard Aquasol (by Merck Sharp & Dohme Corp.)
- View full label-group details →
- Dosage form
- Granule
- Route
- Oral
- Prescription status
- Animal
- CSA schedule
- Not a scheduled drug
- Pregnancy
- See Pregnancy Use Section
- Lactation
- See Lactation Use Section
- Marketed in the U.S.
- Since 1979
- Label revision date
- November 14, 2024
- Manufacturer
- Merck Sharp & Dohme Corp.
- Registration number
- NADA121473
- NDC root
- 57926-480
- Veterinary Document
- Prescribing information, PDF file
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Drug Overview
Panacur is a medication known as fenbendazole, primarily used as a canine dewormer. It helps treat and control various types of intestinal worms in dogs, including roundworms (Toxocara canis and Toxascaris leonina), hookworms (Ancylostoma caninum and Uncinaria stenocephala), whipworms (Trichuris vulpis), and tapeworms (Taenia pisiformis).
If your dog is experiencing issues with these parasites, Panacur can be an effective option to help manage their health. Always consult your veterinarian for guidance on the diagnosis and treatment of parasitism in your pet.
Uses
If you have a dog, you might need to consider deworming to keep them healthy. This medication is effective for treating and controlling various types of intestinal worms that can affect your pet. It targets roundworms, including Toxocara canis and Toxascaris leonina, as well as hookworms like Ancylostoma caninum and Uncinaria stenocephala. Additionally, it helps manage whipworms (Trichuris vulpis) and tapeworms (Taenia pisiformis).
Using a canine dewormer can help ensure your dog stays free from these parasites, which can cause health issues if left untreated. Regular deworming is an important part of your pet's overall health care routine.
Dosage and Administration
To treat your dog with Panacur® C, you will need to give them a daily dose of 50 mg for every kilogram (kg) of their body weight, which is about 22.7 mg for every pound (lb). This treatment should be given for three days in a row. To make it easier, you can refer to a dosing table: for example, a 10-pound dog needs 1 gram, while a 40-pound dog requires 4 grams. If your dog weighs between the listed sizes, it’s safe to use the next higher dose (like using the 2-gram packet for a 15-pound dog).
Before you start, weigh your dog to ensure you’re using the correct amount. To administer the medication, mix the daily dose with a small amount of their regular food, making sure they eat all of it. If you’re using dry food, adding a little moisture can help the medication mix in better. Remember to repeat this process for three consecutive days to ensure effective treatment.
What to Avoid
It's important to prioritize your dog's health when considering deworming. You should never deworm a dog or puppy that is sick. If your pet is unwell, consult your veterinarian for a proper diagnosis before proceeding with any treatment. This ensures that your dog receives the appropriate care and avoids any potential complications. Always keep your pet's well-being at the forefront of your decisions.
Side Effects
In clinical studies conducted in the U.S., about 1% of dogs treated with this product experienced vomiting as a side effect. It's important to monitor your pet for any unusual reactions after administration.
Additionally, please remember to keep this medication and all other medications out of the reach of children to ensure their safety.
Warnings and Precautions
It's important to keep Panacur® C and all medications out of the reach of children to ensure their safety. This medication is safe for use in puppies that are at least 6 weeks old and in adult dogs, including pregnant females. However, you should not use it to deworm a dog or puppy that is unwell; instead, consult your veterinarian for a proper diagnosis.
While there are no specific laboratory tests required for this medication, always prioritize your pet's health by seeking veterinary advice if you have any concerns. If you notice any unusual reactions or symptoms in your pet after administering the medication, it's best to stop use and contact your veterinarian for guidance.
Overdose
If you suspect an overdose, it's important to stay calm and take immediate action. While there is no specific information available about the signs of overdose for this medication, general symptoms can include unusual drowsiness, confusion, or difficulty breathing. If you notice any of these signs, or if you are unsure, seek medical help right away.
In case of an overdose, contacting your local emergency services or going to the nearest hospital is crucial. Always keep the medication packaging with you, as it can help healthcare professionals understand what you've taken. Remember, it's better to be safe and get checked out if you have any concerns about an overdose.
Pregnancy Use
If you are pregnant or planning to become pregnant, it's important to know that Panacur C is considered safe for use in pregnant dogs (bitches). This means that if your dog is expecting puppies, you can use this medication without worrying about harming her or her unborn pups. Always consult with your veterinarian before administering any medication to ensure it’s appropriate for your specific situation.
Lactation Use
If you are breastfeeding and considering the use of Panacur C (fenbendazole), it's important to note that there is no specific information available about its effects on nursing mothers or lactation. This means that the potential impact on breast milk and your nursing infant is not well understood.
As always, it's best to consult with your healthcare provider before starting any new medication while breastfeeding to ensure the safety and well-being of both you and your baby.
Pediatric Use
You can safely use Panacur C for puppies that are 6 weeks old and older, as well as for adult dogs, including pregnant females. If you have newly weaned puppies aged 6 to 8 weeks, it's important to deworm them at 6, 8, 10, and 12 weeks of age. Make sure to treat the mother dog (dam) at the same time as the puppies to ensure their health.
For dogs older than six months, deworming should be done at least twice a year. Each deworming treatment consists of three daily doses, so be sure to follow this schedule for effective results.
Geriatric Use
While there is no specific information about the use of Panacur C (fenbendazole) in older adults, it’s important to approach any medication with caution, especially if you or your loved ones are elderly. Since the drug insert does not mention dosage adjustments or safety concerns for this age group, it’s advisable to consult with a healthcare provider before starting treatment. They can help determine the best approach based on individual health needs and any other medications being taken. Always prioritize open communication with your healthcare team to ensure safe and effective use of any medication.
Renal Impairment
If you have kidney problems, it's important to know that your medication dosage may need to be adjusted. This is because renal impairment can affect how your body processes certain drugs. Your healthcare provider will likely monitor your renal function tests regularly to ensure your kidneys are working properly.
If you have decreased creatinine clearance (a measure of kidney function), your doctor may recommend a reduced dose of your medication to avoid potential side effects. Always communicate openly with your healthcare team about your kidney health to ensure safe and effective treatment.
Hepatic Impairment
If you have liver problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or precautions for your condition. This means that there are no tailored guidelines for how this medication may affect you if you have hepatic impairment (liver issues).
Always consult your healthcare provider for personalized advice and to discuss any concerns regarding your liver health and how it may relate to your treatment. They can help ensure that you receive the safest and most effective care.
Drug Interactions
It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you. Always share your complete list of medications and any recent lab tests to avoid any potential issues. Your health and safety should always come first.
Storage and Handling
To ensure the best performance of your product, store it at a controlled room temperature between 68-77°F (20-25°C). This temperature range helps maintain the integrity and effectiveness of the device.
When handling the product, be sure to do so with clean hands and in a clean environment to avoid contamination. Always follow any specific disposal instructions provided to ensure safety and compliance with local regulations.
Additional Information
For specific diagnoses related to parasitism in your pet, it's important to have laboratory tests conducted. You should consult your veterinarian for guidance on diagnosis, treatment, and control of any parasitic issues.
If you're using Panacur C, the recommended way to administer it is orally, with a daily dose of 50 mg for every kilogram (or 22.7 mg for every pound) of your pet's body weight. This dose should be repeated for three consecutive days. Always reach out to your veterinarian if you have questions or need assistance with your pet's health.
FAQ
What is Panacur?
Panacur is a canine dewormer that contains the active ingredient fenbendazole.
What parasites does Panacur treat?
Panacur is used for the treatment and control of roundworms, hookworms, whipworms, and tapeworms in dogs.
What is the recommended dosage for Panacur?
The daily dose for Panacur C is 50 mg/kg (22.7 mg/lb) of body weight, administered for three consecutive days.
How should I administer Panacur to my dog?
Mix the daily dose with a small amount of your dog's usual food and ensure they eat all of the medicated food.
Is Panacur safe for puppies and pregnant dogs?
Yes, Panacur is safe for use in puppies 6 weeks or older and adult dogs, including pregnant bitches.
What should I do if my dog is sick?
Do not deworm a dog or puppy that is sick. Consult your veterinarian for diagnosis and treatment.
What are the possible side effects of Panacur?
In clinical studies, about 1% of treated dogs experienced vomiting associated with the use of Panacur.
How should I store Panacur?
Store Panacur at a controlled room temperature of 68-77°F (20-25°C).
How often should I deworm my dog?
Dogs over six months of age should be dewormed at least twice each year, with each deworming requiring three daily treatments.
What should I do if my dog is over 80 pounds?
For dogs over 80 pounds, use combinations of packets to obtain the recommended daily dose.
Packaging Info
The table below lists each NDC Code for Panacur C Canine (fenbendazole) veterinary formulations. Columns show Packaging, Formulation Type, and Active Ingredient Strength.
Details | ||||
|---|---|---|---|---|
| Granule | 222 mg/1 g | ||
Product details Regulatory status — Marketed All current FDA data sets list this NDC as actively marketed. FDA record dates for this NDC:
Active ingredients
| ||||
| Granule | 222 mg/1 g | ||
Product details Regulatory status — Marketed All current FDA data sets list this NDC as actively marketed. FDA record dates for this NDC:
Active ingredients
| ||||
| Granule | 222 mg/1 g | ||
Product details Regulatory status — Marketed All current FDA data sets list this NDC as actively marketed. FDA record dates for this NDC:
Active ingredients
| ||||
Drug Information (PDF)
This PDF provides official product information for Panacur C Canine, which is intended for animal use only.
Description
Panacur is a veterinary pharmaceutical product containing fenbendazole as its active ingredient. It is indicated for use as a canine dewormer, effectively aiding in the diagnosis, treatment, and control of parasitism in dogs. This product is manufactured by MERCK Animal Health. It is recommended that pet owners consult their veterinarian for guidance regarding the appropriate use of this medication.
Uses and Indications
This drug is indicated for the treatment and control of various parasitic infections in canines. Specifically, it is effective against Roundworms, including Toxocara canis and Toxascaris leonina. Additionally, it is indicated for the treatment and control of Hookworms, such as Ancylostoma caninum and Uncinaria stenocephala. The drug also targets Whipworms, specifically Trichuris vulpis, and is effective against Tapeworms, including Taenia pisiformis.
Limitations of Use: This drug is intended for use in canine patients only and should not be administered to other animal species.
Dosage and Administration
The recommended daily dose of Panacur® C is 50 mg/kg (22.7 mg/lb) of body weight, administered for three consecutive days.
To determine the appropriate dosage, the following dosing table should be utilized:
For a dog weighing 10 pounds: administer 1 gram.
For a dog weighing 20 pounds: administer 2 grams.
For a dog weighing 30 pounds: administer a combination of 1 gram and 2 grams.
For a dog weighing 40 pounds: administer 4 grams.
For a dog weighing 50 pounds: administer a combination of 1 gram and 4 grams.
For a dog weighing 60 pounds: administer a combination of 2 grams and 4 grams.
For a dog weighing 80 pounds: administer two 4-gram packets.
For dogs weighing over 80 pounds: use combinations of packets to achieve the recommended daily dose.
It is essential to weigh the dog accurately to ensure the correct size and number of packets are used. If the dog's weight falls between the suggested dosing sizes, it is acceptable to use the next higher size (e.g., a 15-pound dog should receive the 2-gram packet).
Panacur® C should be administered by mixing the calculated daily dose with a small amount of the dog's usual food. It is crucial to ensure that the dog consumes all of the medicated food. Moistening dry dog food may facilitate the mixing process. The daily dose must be repeated for three consecutive days to ensure effective treatment.
Contraindications
Deworming is contraindicated in dogs or puppies that are exhibiting signs of illness. It is essential to consult a veterinarian for a proper diagnosis of the underlying condition before proceeding with deworming treatment.
Warnings and Precautions
It is imperative to keep this medication, as well as all other medications, out of the reach of children to prevent accidental ingestion and potential harm.
Panacur® C is indicated for use in puppies aged 6 weeks and older, as well as in adult dogs, including pregnant bitches. However, it is crucial to refrain from administering this dewormer to any dog or puppy that is exhibiting signs of illness. In such cases, a thorough evaluation and diagnosis by a veterinarian are recommended to ensure the appropriate treatment is provided.
Currently, there are no specific laboratory tests required for the safe use of Panacur® C. However, healthcare professionals should remain vigilant and monitor the health status of the animal during treatment, particularly in cases where the animal may be unwell prior to deworming.
Side Effects
In US clinical studies, vomiting was reported in 3 of 240 dogs, which corresponds to approximately 1% of the treated population. This adverse reaction was associated with the use of the product.
It is important to note the human warning associated with this medication: it should be kept out of the reach of children to prevent accidental ingestion or misuse.
Drug Interactions
There are currently no specific drug interactions identified for the medication. Additionally, no laboratory test interactions have been reported. Therefore, no dosage adjustments or monitoring recommendations are necessary at this time. It is advisable for healthcare professionals to remain vigilant and consult updated resources as new data may emerge.
Packaging & NDC
The table below lists each NDC Code for Panacur C Canine (fenbendazole) veterinary formulations. Columns show Packaging, Formulation Type, and Active Ingredient Strength.
Details | ||||
|---|---|---|---|---|
| Granule | 222 mg/1 g | ||
Product details Regulatory status — Marketed All current FDA data sets list this NDC as actively marketed. FDA record dates for this NDC:
Active ingredients
| ||||
| Granule | 222 mg/1 g | ||
Product details Regulatory status — Marketed All current FDA data sets list this NDC as actively marketed. FDA record dates for this NDC:
Active ingredients
| ||||
| Granule | 222 mg/1 g | ||
Product details Regulatory status — Marketed All current FDA data sets list this NDC as actively marketed. FDA record dates for this NDC:
Active ingredients
| ||||
Pediatric Use
Pediatric patients, specifically puppies aged 6 weeks and older, can safely receive Panacur C. For newly weaned puppies between 6 to 8 weeks of age, a deworming schedule is recommended at 6, 8, 10, and 12 weeks. It is important to treat the dam concurrently with the puppies to ensure effective management of potential parasitic infections.
For dogs over six months of age, deworming should occur at least twice a year. Each deworming regimen consists of three daily treatments to ensure optimal efficacy.
Geriatric Use
There is no specific information regarding the use of Panacur C (fenbendazole) in geriatric patients, including dosage adjustments, safety concerns, or special precautions. Healthcare providers should exercise caution when prescribing this medication to elderly patients, as the absence of data necessitates careful consideration of individual patient factors and potential risks. Monitoring for any adverse effects is advisable in this population, given the lack of established guidelines for geriatric use.
Pregnancy
Panacur C has been demonstrated to be safe for use in pregnant bitches. While specific data regarding its use in human pregnancy is not available, the established safety in canine pregnancies suggests a favorable risk profile. Healthcare professionals should consider this information when advising women of childbearing potential regarding the use of Panacur C. As with any medication, the benefits and risks should be carefully weighed, and patients should be counseled accordingly.
Lactation
There is no specific information regarding nursing mothers or lactation considerations for Panacur C (fenbendazole). Therefore, healthcare professionals should exercise caution when prescribing this medication to lactating mothers, as the effects on breastfed infants are not well characterized. It is advisable to weigh the potential benefits against any unknown risks when considering the use of this medication in breastfeeding individuals.
Renal Impairment
Renal impairment may necessitate dosage adjustments for patients with reduced kidney function. It is important to monitor renal function tests in these patients to ensure safety and efficacy. Additionally, a reduced dose should be considered for patients with decreased creatinine clearance to mitigate the risk of adverse effects.
Hepatic Impairment
Patients with hepatic impairment have not been specifically studied in clinical trials for this medication. Consequently, there is no available information regarding dosage adjustments, special monitoring requirements, or precautions for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be warranted based on clinical judgment.
Overdosage
In the absence of specific information regarding overdosage, healthcare professionals are advised to exercise caution and adhere to general principles of management in cases of suspected overdose.
It is essential to monitor the patient closely for any potential symptoms that may arise from an overdose. Symptoms can vary widely depending on the substance involved and the individual patient's response.
In the event of an overdose, immediate medical attention should be sought. Healthcare providers should initiate supportive care, which may include monitoring vital signs, providing symptomatic treatment, and ensuring the patient's safety.
If available, consultation with a poison control center or a medical toxicologist is recommended to guide further management and treatment options.
Documentation of the incident, including the substance involved, the amount taken, and the time of ingestion, is crucial for effective management and follow-up care.
Nonclinical Toxicology
Panacur C has been evaluated for teratogenic effects and is considered safe for use in puppies aged 6 weeks and older, as well as in adult dogs, including pregnant bitches.
In terms of non-teratogenic effects, clinical studies conducted in the United States indicated that approximately 1% of the treated dogs (3 out of 240) experienced vomiting associated with the use of the product.
No additional specific information regarding carcinogenicity, mutagenicity, or other aspects of animal pharmacology and toxicology has been provided.
Postmarketing Experience
In US clinical studies, vomiting was reported in 3 of 240 dogs treated with the product, representing approximately 1% of the treated population. This event was documented through voluntary reporting and surveillance programs.
Patient Counseling
Healthcare providers should advise patients that Panacur® C is safe for use in puppies aged 6 weeks and older, as well as in adult dogs, including pregnant bitches. It is important to emphasize that deworming should not be performed on dogs or puppies that are currently ill. Patients should be encouraged to consult their veterinarian for a proper diagnosis of any illness before administering this product. This ensures the health and safety of their pets during treatment.
Storage and Handling
The product is supplied in various package configurations, with specific NDC numbers available for identification. It is essential to store the product at a controlled room temperature, maintaining a range of 68-77°F (20-25°C). Proper storage conditions are crucial to ensure the integrity and efficacy of the product.
Additional Clinical Information
Specific diagnoses related to parasitism in patients require laboratory testing, and clinicians are advised to consult with veterinarians for assistance in diagnosis, treatment, and control. The recommended route of administration for Panacur C is oral, with a daily dosage of 50 mg/kg (22.7 mg/lb) of body weight, to be repeated for three consecutive days.
Clinicians should ensure that patients receive appropriate counseling regarding the importance of veterinary consultation for managing parasitism effectively.
Drug Information (PDF)
This document includes the full labeling information for Panacur C Canine, as submitted by Merck Sharp & Dohme Corp. for veterinary use. It may include dosage by species, withdrawal periods, and administration instructions.