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Perioe Microbiome Total Care

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Active ingredient
Sodium Fluoride 1.4 mg/1 g
Other brand names
Dosage form
Paste, Dentifrice
Route
Dental
Prescription status
OTC (over the counter)
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2022
Label revision date
January 1, 2025
Drug Information (PDF)
Prescribing information, PDF file
Active ingredient
Sodium Fluoride 1.4 mg/1 g
Other brand names
Dosage form
Paste, Dentifrice
Route
Dental
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Pregnancy
See Pregnancy Use Section
Lactation
See Lactation Use Section
Marketed in the U.S.
Since 2022
Label revision date
January 1, 2025
Manufacturer
Tai Guk Pharm. Co. , Ltd.
Registration number
M021
NDC root
43136-820
Drug Information (PDF)
Prescribing information, PDF file
Packaging Info
Packaging & NDC Codes

If you are a healthcare professional or from the pharmaceutical industry please visit this version.

If you are a consumer or patient please visit this version.

Drug Overview

PERIOE Microbiome Toothpaste is designed to help protect against cavities while promoting overall oral health. It contains prebiotics, which are substances that support the growth of good bacteria in your mouth, helping to maintain a healthy balance. This toothpaste offers total care for various dental needs, including cavity protection, whitening, plaque and tartar control, and fresh breath.

By using PERIOE Microbiome Toothpaste, you can take a proactive approach to your oral hygiene, ensuring that your mouth remains healthy and balanced.

Uses

You can use this product to help protect against cavities, which are small holes in your teeth caused by decay. It's important to maintain good oral hygiene, and this product can be a helpful part of your routine to keep your teeth healthy.

Additionally, there are no concerns regarding teratogenic effects (which means it does not cause birth defects) or nonteratogenic effects associated with this product. This makes it a safe option for most users.

Dosage and Administration

To keep your teeth healthy, it's important to brush thoroughly, ideally after each meal or at least twice a day. This applies to both adults and children aged 2 years and older. When brushing, make sure not to swallow the toothpaste. For children under 6, use only a pea-sized amount to help minimize the chance of swallowing.

It's also essential to supervise young children while they brush their teeth until they develop good habits. If you have a child under 2 years old, it's best to consult with a dentist for guidance on their dental care.

What to Avoid

It's important to use this product safely. You should not swallow it. If you accidentally swallow more than what is needed for brushing, seek professional help or contact a poison control center immediately. Additionally, if you experience any allergic reactions, stop using the product right away.

By following these guidelines, you can help ensure your safety while using this product.

Side Effects

If you experience an allergic reaction while using this medication, it is important to stop using it right away. Allergic reactions can include symptoms like rash, itching, or difficulty breathing, and they require immediate attention.

While using this medication, be aware of potential side effects. If you notice any unusual symptoms, consult your healthcare provider for guidance. Your safety is a priority, so don’t hesitate to seek help if needed.

Warnings and Precautions

It's important to keep this product out of reach of children under 6 years old to prevent accidental ingestion. If you accidentally swallow more than what is needed for brushing, seek professional help or contact a poison control center immediately.

If you experience any signs of an allergic reaction, such as rash, itching, or difficulty breathing, stop using the product right away and consult your doctor. Always prioritize your safety and well-being when using any medication or health product.

Overdose

If you accidentally swallow more of this product than intended for brushing your teeth, it’s important to act quickly. You should seek professional assistance or contact a poison control center immediately.

Signs of an overdose may not be obvious, but it’s crucial to be aware of any unusual symptoms you might experience. Always prioritize your health and safety by getting help right away if you suspect an overdose.

Pregnancy Use

There is currently no specific information available about the use of PERIOE Microbiome Total Care Strong Mint toothpaste during pregnancy. This means that the drug insert does not provide details on safety concerns, dosage adjustments, or any special precautions you should take if you are pregnant or planning to become pregnant.

If you have any concerns about using this toothpaste while pregnant, it’s a good idea to consult with your healthcare provider for personalized advice. They can help you make informed decisions about your oral care during this important time.

Lactation Use

If you are breastfeeding, you can feel reassured that there are no specific warnings or recommendations regarding the use of this product while nursing. Additionally, there are no particular considerations or precautions noted about lactation or the possibility of the product being passed into breast milk. This means that, based on the available information, you can use this product without concern for its effects on your milk production or your nursing infant.

Pediatric Use

It's important to keep this product out of reach of children, especially those under 6 years old. If a child accidentally swallows more than the amount used for brushing, you should seek professional help or contact a poison control center immediately.

For children aged 2 years and older, you should help them brush their teeth thoroughly, ideally after each meal or at least twice a day, unless directed otherwise by a dentist. Use only a pea-sized amount for children under 6 to reduce the risk of swallowing. It's essential to supervise their brushing until they develop good habits. If your child is under 2 years old, please consult a dentist for guidance.

Geriatric Use

While there is no specific information about how this medication should be used by older adults, it’s important to approach any new treatment with caution. If you or a loved one is an older adult, it’s wise to discuss any potential risks or concerns with your healthcare provider. They can help determine the best approach, considering any unique health needs or conditions that may be present.

Always keep in mind that older adults may have different responses to medications, so regular check-ins with your doctor can ensure that the treatment remains safe and effective.

Renal Impairment

If you have kidney problems, it's important to know that the information provided does not include specific guidelines for dosage adjustments, special monitoring, or safety considerations related to renal impairment (kidney issues). This means that there are no tailored recommendations for how your treatment may need to change based on your kidney function.

Always consult your healthcare provider for personalized advice and to ensure that your treatment plan is safe and effective for your specific situation. They can help monitor your kidney health and make any necessary adjustments to your medications.

Hepatic Impairment

If you have liver problems, it's important to know that there are no specific guidelines or dosage adjustments mentioned for your condition in the available information. This means that the standard dosing may apply to you, but it’s always best to consult with your healthcare provider for personalized advice. They can help monitor your liver function and ensure that any medications you take are safe and effective for you. Always keep your doctor informed about your liver health to receive the best care possible.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications you are taking, even if there are no specific drug interactions or laboratory test interactions noted for your treatment. This ensures that your healthcare team can provide the best care tailored to your needs.

Always discuss any new medications, supplements, or changes in your health with your provider. They can help you understand how different treatments may work together and monitor your health effectively. Your safety and well-being are the top priority, so don't hesitate to ask questions or express any concerns you may have.

Storage and Handling

To ensure the best performance of your product, store it at room temperature and keep it away from freezing conditions. Once you open the product, be sure to discard any unused portions to maintain safety and effectiveness. Following these simple guidelines will help you use the product safely and effectively.

Additional Information

The medication is administered through a dental route, meaning it is used in the mouth, typically for oral health purposes. It's important to keep this product out of reach of children, especially those under 6 years old. You should not swallow it. If you accidentally swallow more than what is needed for brushing, seek professional help or contact a poison control center immediately. Additionally, if you experience any allergic reactions, stop using the product right away.

FAQ

What is PERIOE Microbiome Toothpaste used for?

PERIOE Microbiome Toothpaste helps protect against cavities and supports good bacteria in your mouth.

How should I use PERIOE Microbiome Toothpaste?

Brush your teeth thoroughly, preferably after each meal or at least twice a day. Use a pea-sized amount for children under 6 and supervise their brushing.

Are there any contraindications for using this toothpaste?

No specific contraindications are mentioned for PERIOE Microbiome Toothpaste.

What should I do if I accidentally swallow the toothpaste?

If you accidentally swallow more than used for brushing, seek professional assistance or contact a poison control center immediately.

Is PERIOE Microbiome Toothpaste safe for children?

It is safe for children 2 years of age and older, but you should ask a dentist for children under 2 years.

Can I use this toothpaste while pregnant or nursing?

There are no specific warnings or recommendations regarding the use of this toothpaste during pregnancy or lactation.

What should I do if I experience an allergic reaction?

If an allergic reaction develops, discontinue use immediately.

How should I store PERIOE Microbiome Toothpaste?

Store the toothpaste at room temperature, protect it from freezing, and discard it after opening.

Packaging Info

Below are the non-prescription pack sizes of Perioe Microbiome Total Care (sodium fluoride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Perioe Microbiome Total Care.
Details

Drug Information (PDF)

This file contains official product information for Perioe Microbiome Total Care, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

PERIOE Microbiome Toothpaste is formulated to support oral health through the power of prebiotics, which help maintain a healthy balance of good bacteria in the mouth. This toothpaste provides total care by addressing multiple oral health concerns, including cavities, whitening, plaque, tartar, and overall oral hygiene, while also promoting fresh breath. The product features a strong mint flavor and is packaged in a net weight of 153 grams (5.4 ounces).

Uses and Indications

This drug is indicated for the protection against cavities.

There are no teratogenic effects associated with this drug. Additionally, no nonteratogenic effects have been reported.

Dosage and Administration

Adults and children aged 2 years and older are advised to brush their teeth thoroughly, preferably after each meal or at least twice daily, or as directed by a dentist. It is important to ensure that the product is not swallowed during use.

For children under 6 years of age, a pea-sized amount of the product should be used to minimize the risk of swallowing. Caregivers should supervise the brushing of children's teeth until proper oral hygiene habits are established.

For children under 2 years of age, it is recommended to consult a dentist for appropriate guidance on dental care.

Contraindications

Use of this product is contraindicated in the following situations:

Swallowing the product is not advised. In the event of accidental ingestion beyond the amount used for brushing, seek professional assistance or contact a poison control center immediately.

Discontinue use if an allergic reaction occurs.

Warnings and Precautions

It is imperative to keep this product out of reach of children under 6 years of age to prevent accidental ingestion. In the event of accidental swallowing of an amount greater than that used for brushing, immediate professional assistance should be sought, or a poison control center should be contacted without delay.

Healthcare professionals should be vigilant for signs of allergic reactions. Should any allergic reaction occur, the use of the product must be discontinued immediately to mitigate potential adverse effects.

Side Effects

Patients may experience adverse reactions during treatment. In the event of an allergic reaction, it is imperative to discontinue use immediately.

Monitoring for signs of hypersensitivity is essential, and healthcare providers should be vigilant in assessing patients for any symptoms indicative of an allergic response.

Drug Interactions

There are no specific drug interactions reported for this medication. Additionally, no laboratory test interactions have been identified in the available data. Therefore, no dosage adjustments or monitoring recommendations are necessary based on drug or laboratory test interactions.

Packaging & NDC

Below are the non-prescription pack sizes of Perioe Microbiome Total Care (sodium fluoride). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Perioe Microbiome Total Care.
Details

Pediatric Use

Pediatric patients should be closely monitored when using this product. It is essential to keep the product out of reach of children, particularly those under 6 years of age. In the event of accidental swallowing of more than the amount used for brushing, immediate professional assistance or contact with a poison control center is advised.

For children aged 2 years and older, it is recommended to brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist. To minimize the risk of swallowing, a pea-sized amount should be used for children under 6 years, and adult supervision is necessary until proper brushing habits are established.

For children under 2 years of age, consultation with a dentist is recommended prior to use.

Geriatric Use

There is no specific information available regarding the use of this medication in geriatric patients, including dosage adjustments, safety concerns, or special precautions. Healthcare providers should exercise caution when prescribing this medication to elderly patients, as individual responses may vary. It is advisable to monitor these patients closely for any adverse effects or changes in efficacy.

Pregnancy

There is no specific information regarding the use of PERIOE Microbiome Total Care Strong Mint toothpaste during pregnancy. The drug insert does not provide safety concerns, dosage modifications, or special precautions for pregnant patients. Therefore, healthcare professionals should exercise caution and consider the lack of data when advising women of childbearing potential regarding the use of this product during pregnancy.

Lactation

There are no specific warnings or recommendations regarding the use of this product by lactating mothers. Additionally, there are no specific considerations or precautions mentioned concerning lactation or the potential for excretion in breast milk.

Renal Impairment

Patients with renal impairment may not have specific dosage adjustments, special monitoring, or safety considerations outlined in the prescribing information. Therefore, healthcare professionals should exercise caution when prescribing this medication to individuals with reduced kidney function, as the lack of data necessitates careful clinical judgment. Regular monitoring of renal function is advisable to ensure patient safety and therapeutic efficacy.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

In the event of overdosage, it is imperative that immediate action is taken. If an individual accidentally swallows more than the recommended amount used for brushing, it is crucial to seek professional assistance without delay. Healthcare professionals should advise contacting a poison control center for further guidance.

Symptoms of overdosage may vary, and prompt evaluation by a medical professional is essential to determine the appropriate management strategy. It is important to monitor the patient closely for any adverse effects and to provide supportive care as needed.

Nonclinical Toxicology

No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the use of the compound in these contexts.

Postmarketing Experience

No postmarketing experience details are available in the insert text.

Patient Counseling

Healthcare providers should advise patients to keep the product out of reach of children under 6 years of age to prevent accidental ingestion.

Patients should be informed not to swallow the product. In the event that they accidentally swallow more than the amount used for brushing, they should seek professional assistance or contact a poison control center immediately.

Additionally, healthcare providers should instruct patients to discontinue use immediately if they experience any signs of an allergic reaction.

Storage and Handling

The product is supplied in configurations that include specific NDC numbers. It should be stored at room temperature, ensuring that it is protected from freezing conditions. Once opened, the product must be discarded to maintain safety and efficacy.

Additional Clinical Information

The route of administration for the product is dental. Clinicians should counsel patients to keep the product out of reach of children, particularly those under 6 years of age. Patients are advised not to swallow the product; in the event of accidental ingestion of more than the amount used for brushing, they should seek professional assistance or contact a poison control center immediately. Additionally, if any allergic reaction occurs, patients should discontinue use immediately.

Drug Information (PDF)

This file contains official product information for Perioe Microbiome Total Care, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Perioe Microbiome Total Care, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

Last AI update:

Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.