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Perricone Md Acne Relief Gentle and Soothing Cleanser

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Active ingredient
Salicylic Acid 2 g/100 mL
Other brand names
Dosage form
Gel
Route
Topical
Prescription status
OTC (over the counter)
Marketed in the U.S.
Since 2021
Label revision date
October 31, 2025
Active ingredient
Salicylic Acid 2 g/100 mL
Other brand names
Dosage form
Gel
Route
Topical
Prescription status
OTC (over the counter)
CSA schedule
Not a scheduled drug
Marketed in the U.S.
Since 2021
Label revision date
October 31, 2025
Manufacturer
THG Beauty USA LLC
Registration number
M006
NDC root
84448-539

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If you are a consumer or patient please visit this version.

Drug Overview

If you're looking for a treatment for acne, this medication is designed specifically for that purpose. It helps to reduce the appearance of acne, which can be a common skin condition affecting many people. While the exact details of how it works are not provided, its primary goal is to improve your skin's condition by targeting acne.

Uses

If you're dealing with acne, this medication can help you manage and treat your condition. Acne is a common skin issue that can affect people of all ages, and this treatment is specifically designed to reduce breakouts and improve the overall appearance of your skin. By targeting the factors that contribute to acne, it aims to provide you with clearer skin and boost your confidence.

Dosage and Administration

To use this acne treatment effectively, start by lathering a quarter-sized amount in your hands and gently massaging it onto your damp skin. Make sure to rinse thoroughly with warm water. For the best results, follow this with the ACNE RELIEF Calming Treatment & Hydrator in the morning and the ACNE RELIEF Retinol Treatment & Moisturizer in the evening.

If you experience bothersome dryness or peeling, you should reduce your application to once a day or even every other day. If you’re using this product for the first time, it’s a good idea to perform a sensitivity test. Apply a small amount to one or two small areas of your skin for the first three days. If you don’t feel any discomfort, you can proceed with the full application as described.

What to Avoid

It's important to be aware of specific instructions regarding the use of this medication. While there are no listed contraindications, controlled substance classifications, or risks of abuse or dependence, you should take care if the medication is swallowed. In such a case, seek medical help or contact a Poison Control Center immediately. Your safety is paramount, so always follow these guidelines closely.

Side Effects

When using this medication, you may experience skin irritation and dryness, especially if you are using another topical acne treatment at the same time. To minimize these effects, it’s best to use only one topical acne medication at a time.

Remember, this product is for external use only. If accidentally swallowed, seek medical help or contact a Poison Control Center immediately. Always keep this medication out of reach of children to ensure their safety.

Warnings and Precautions

This medication is for external use only, so be sure to apply it only to your skin. If you are using another topical acne treatment at the same time, you may experience skin irritation and dryness. To minimize this risk, it’s best to use only one topical acne medication at a time.

If you accidentally swallow this medication, seek medical help immediately or contact a Poison Control Center. It's important to act quickly in such situations to ensure your safety.

Overdose

It appears that there is no specific information available regarding overdosage for this medication. However, it's important to be aware of the general signs of an overdose, which can include symptoms like extreme drowsiness, confusion, or difficulty breathing. If you suspect an overdose, it is crucial to seek immediate medical help.

In case of an emergency, call your local emergency services or go to the nearest hospital. Always keep medications out of reach of children and follow the prescribed dosage to prevent any potential risks. If you have any concerns or questions about your medication, don’t hesitate to reach out to your healthcare provider for guidance.

Pregnancy Use

If you are pregnant or planning to become pregnant, it's important to be cautious with the use of salicylic acid, as its safety during pregnancy has not been established. Salicylic acid is contraindicated, meaning it should not be used during this time due to potential risks to your developing baby. There is a possibility of teratogenic effects, which are abnormalities that can occur in the fetus as a result of exposure to certain substances.

To ensure your safety and that of your baby, you should avoid using products containing salicylic acid unless specifically directed by your healthcare provider. Always consult with your doctor before using any medication or treatment during pregnancy.

Lactation Use

If you are breastfeeding, you can feel reassured that there are no specific warnings or recommendations regarding the use of this product while nursing. Additionally, there is no information available about whether this product is excreted in breast milk or any potential risks to your infant. Always consult with your healthcare provider if you have any concerns or questions about medications while breastfeeding.

Pediatric Use

The information provided does not specifically address the use of this medication in children. There are no recommended ages, dosage differences, or safety concerns outlined for pediatric use. As a parent or caregiver, it's important to consult with a healthcare professional for guidance on the appropriate use of this medication for children, as they can provide tailored advice based on your child's specific needs.

Geriatric Use

While there is no specific information about how this medication should be used by older adults, it’s important to approach any new treatment with caution. If you or a loved one is an older adult, it’s always a good idea to discuss any medications with a healthcare provider. They can help ensure that the treatment is safe and appropriate, considering any unique health needs or conditions that may be present.

Since there are no dosage adjustments or special precautions mentioned for elderly patients, your healthcare provider will be the best resource for personalized advice. Always keep them informed about all medications being taken to avoid potential interactions and to ensure the best care.

Renal Impairment

It appears that there is no specific information regarding renal impairment (kidney problems) in the provided text. This means there are no dosage adjustments, special monitoring, or safety considerations outlined for patients with kidney issues. If you have concerns about how your kidney health may affect your treatment, it's important to discuss this with your healthcare provider, who can offer personalized guidance based on your individual situation.

Hepatic Impairment

If you have liver problems, it's important to know that there are no specific guidelines, dosage adjustments, or special monitoring requirements mentioned for your condition in the available information. This means that the standard recommendations apply, but you should always consult your healthcare provider for personalized advice. They can help ensure that any medications you take are safe and appropriate for your liver health.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. Currently, there are no specific drug interactions or laboratory test interactions noted for this medication. However, every individual’s health situation is unique, and your provider can help ensure that your treatment plan is safe and effective for you. Always share your complete list of medications and any lab tests you undergo to avoid potential issues.

Storage and Handling

To ensure the best performance of your product, store it at room temperature and keep it away from direct light. It's important not to freeze the product, as this can affect its effectiveness. Once you open the product, be sure to discard it after use to maintain safety and quality.

By following these simple storage and handling guidelines, you can help ensure that the product remains safe and effective for your needs.

Additional Information

To use this product effectively, start by applying a quarter-sized amount to your hands and gently massaging it onto damp skin. Rinse thoroughly with warm water. For optimal results, follow up with the ACNE RELIEF Calming Treatment & Hydrator in the morning and the ACNE RELIEF Retinol Treatment & Moisturizer in the evening. If you experience bothersome dryness or peeling, consider reducing your application to once a day or every other day.

If you're using this product for the first time, it's a good idea to perform a sensitivity test. Apply a small amount to one or two affected areas over the first three days. If you don’t experience any discomfort, you can proceed with the full application as directed.

FAQ

What is this drug used for?

This drug is used for the treatment of acne.

How should I use this product?

Lather a quarter-sized amount in your hands, gently massage it onto damp skin, and rinse thoroughly with warm water. For best results, follow with ACNE RELIEF Calming Treatment & Hydrator in the morning and ACNE RELIEF Retinol Treatment & Moisturizer in the evening.

What should I do if I experience dryness or peeling?

If bothersome dryness or peeling occurs, reduce application to once a day or every other day.

How can I test for sensitivity to this product?

Apply the product sparingly to one or two small affected areas during the first 3 days. If no discomfort occurs, you can follow the regular usage directions.

Are there any contraindications for this product?

There are no listed contraindications, but if swallowed, you should get medical help or contact a Poison Control Center immediately.

Is this product safe to use during pregnancy?

The safety of salicylic acid during pregnancy has not been established, and it is contraindicated due to potential risks to the fetus.

What should nursing mothers know about this product?

There are no specific warnings or recommendations regarding the use of this product by nursing mothers.

How should I store this product?

Store at room temperature, protect from light, and do not freeze. Discard after opening.

What should I do if I accidentally swallow this product?

If swallowed, get medical help or contact a Poison Control Center right away.

Packaging Info

Below are the non-prescription pack sizes of Perricone Md Acne Relief Gentle and Soothing Cleanser (salicylic acid). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Perricone Md Acne Relief Gentle and Soothing Cleanser.
Details

Drug Information (PDF)

This file contains official product information for Perricone Md Acne Relief Gentle and Soothing Cleanser, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Description

No description information is available for the specified drug.

Uses and Indications

This drug is indicated for the treatment of acne. It is intended for use in patients diagnosed with this condition to help reduce the severity and prevalence of acne lesions.

Dosage and Administration

A quarter-sized amount of the product should be lathered in the hands and gently massaged onto damp skin. It is essential to rinse thoroughly with warm water. For optimal results, it is recommended to follow this application with ACNE RELIEF Calming Treatment & Hydrator in the morning and ACNE RELIEF Retinol Treatment & Moisturizer in the evening.

In cases where bothersome dryness or peeling occurs, the frequency of application should be reduced to once a day or every other day.

For new users, a sensitivity test is advised. This involves applying the product sparingly to one or two small affected areas during the first three days. If no discomfort is experienced, the user may proceed with the full application as directed.

Contraindications

There are no specific contraindications listed for this product. However, it is imperative to seek immediate medical assistance or contact a Poison Control Center if the product is swallowed.

Warnings and Precautions

For external use only. Healthcare professionals should advise patients to avoid concurrent use of this product with other topical acne medications, as this may increase the risk of skin irritation and dryness. In the event that irritation occurs, it is recommended that patients limit their use to one topical acne medication at a time to mitigate adverse effects.

In cases of accidental ingestion, immediate medical assistance should be sought, or the patient should contact a Poison Control Center without delay. It is crucial to ensure that patients are aware of these precautions to promote safe and effective use of the medication.

Side Effects

Patients using this topical acne medication may experience skin irritation and dryness, particularly if they concurrently use another topical acne treatment. It is advised that only one topical acne medication be used at a time to minimize the risk of irritation.

This product is intended for external use only. In the event of accidental ingestion, patients should seek medical assistance or contact a Poison Control Center immediately. Additionally, it is important to keep this medication out of reach of children to prevent accidental swallowing.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there are no known interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are necessary at this time.

Packaging & NDC

Below are the non-prescription pack sizes of Perricone Md Acne Relief Gentle and Soothing Cleanser (salicylic acid). Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Perricone Md Acne Relief Gentle and Soothing Cleanser.
Details

Pediatric Use

Pediatric use has not been specifically addressed in the provided text. There are no recommended age ranges, dosing differences, safety concerns, or special precautions for pediatric patients mentioned. Healthcare professionals should consider this lack of information when prescribing and monitoring treatment in children.

Geriatric Use

There is no specific information regarding the use of this medication in geriatric patients, including dosage adjustments, safety concerns, or special precautions. Healthcare providers should exercise caution when prescribing this medication to elderly patients, as individual responses may vary. Monitoring for potential adverse effects and therapeutic efficacy is recommended in this population.

Pregnancy

The safety of salicylic acid during pregnancy has not been established. Salicylic acid is contraindicated in pregnancy due to potential risks to the fetus, including the risk of teratogenic effects associated with its use. Pregnant women should avoid the use of salicylic acid-containing products unless directed by a healthcare provider. It is essential for healthcare professionals to counsel pregnant patients regarding these risks and to consider alternative treatment options when necessary.

Lactation

There are no specific warnings or recommendations regarding the use of this product by lactating mothers. Additionally, there is no information available about the potential for excretion in breast milk or any associated risks to breastfed infants.

Renal Impairment

There is no information available regarding dosage adjustments, special monitoring, or safety considerations for patients with renal impairment. Healthcare professionals should exercise caution and consider the lack of specific guidance when prescribing to patients with reduced kidney function.

Hepatic Impairment

There is no information available regarding the use of this medication in patients with hepatic impairment. Consequently, there are no dosage adjustments, special monitoring requirements, or precautions specified for individuals with compromised liver function. Healthcare professionals should exercise caution and consider the lack of data when prescribing this medication to patients with liver problems.

Overdosage

There is currently no specific information available regarding overdosage for this medication. In the absence of documented overdosage data, healthcare professionals are advised to exercise caution and monitor patients closely for any unusual symptoms or adverse effects that may arise following administration.

In the event of suspected overdosage, it is recommended that healthcare providers initiate supportive care and symptomatic treatment as necessary. Continuous monitoring of vital signs and clinical status is essential to ensure patient safety.

Healthcare professionals should also consider consulting a poison control center or relevant toxicology resources for guidance on management strategies tailored to the specific circumstances of the overdosage event.

Nonclinical Toxicology

No information is available regarding teratogenic or non-teratogenic effects. Additionally, there is no data provided concerning nonclinical toxicology, animal pharmacology, or toxicology.

Postmarketing Experience

No postmarketing experience details are available in the insert text.

Patient Counseling

Healthcare providers should advise patients to seek immediate medical assistance or contact a Poison Control Center if the medication is swallowed. It is crucial for patients to understand the potential risks associated with accidental ingestion.

Additionally, healthcare providers should inform patients about the likelihood of skin irritation and dryness when using this medication in conjunction with other topical acne treatments. Patients should be counseled to use only one topical acne medication at a time to minimize the risk of irritation. This guidance will help ensure safe and effective use of the medication while reducing the potential for adverse skin reactions.

Storage and Handling

The product is supplied in configurations that include specific NDC numbers. It should be stored at room temperature, ensuring that it is protected from light exposure. Freezing the product is not permitted, as it may compromise its integrity. Once opened, the product must be discarded to ensure safety and efficacy.

Additional Clinical Information

Patients should apply a quarter-sized amount of the product to damp skin, lathering it in their hands and gently massaging it onto the skin before rinsing thoroughly with warm water. For optimal results, it is recommended to follow this with the ACNE RELIEF Calming Treatment & Hydrator in the morning and the ACNE RELIEF Retinol Treatment & Moisturizer in the evening. If patients experience bothersome dryness or peeling, they should reduce the application frequency to once a day or every other day.

For new users, a sensitivity test is advised: apply the product sparingly to one or two small affected areas for the first three days. If no discomfort is noted, patients can proceed with the full application as directed.

Drug Information (PDF)

This file contains official product information for Perricone Md Acne Relief Gentle and Soothing Cleanser, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.

View product document (PDF)

Data Generation & Sources

This page was automatically generated and is maintained by the AllDrugs AI Data-Science Team. It was built from the FDA Structured Product Label (DailyMed) for Perricone Md Acne Relief Gentle and Soothing Cleanser, retrieved by a validated AI data-extraction workflow.

All FDA-listed dosage forms and strengths are shown in the Packaging & NDC Codes section above. Regulatory status appears in the Summary Information panel above and was verified in the FDA National Drug Code directory and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

Learn more in our Editorial Policy

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Primary FDA sources:

Orange Book data shown on this page are limited to Regulatory Status (Rx), Established Pharmacologic Class (EPC), and Mechanism of Action (MoA).

Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.