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Quad Dewormer

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Active ingredients
  • Pyrantel Pamoate 22.7–136 mg
  • Praziquantel 22.7–136 mg
  • Febantel 113.4–680.4 mg
Dosage form
Tablet, Chewable
Route
Oral
Prescription status
Animal
Marketed in the U.S.
Since 2015
Label revision date
February 24, 2026
Active ingredients
  • Pyrantel Pamoate 22.7–136 mg
  • Praziquantel 22.7–136 mg
  • Febantel 113.4–680.4 mg
Dosage form
Tablet, Chewable
Route
Oral
Prescription status
Animal
CSA schedule
Not a scheduled drug
Marketed in the U.S.
Since 2015
Label revision date
February 24, 2026
Manufacturer
Elanco US Inc.
Registration number
NADA141007
NDC roots
58198-0056, 58198-0057, 58198-0058

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Drug Overview

Quad Dewormer is a chewable tablet designed specifically for dogs weighing 45 pounds and greater. It contains a combination of three active ingredients: praziquantel, pyrantel pamoate, and febantel. This medication is effective in removing a variety of common intestinal parasites, including tapeworms (Dipylidium caninum and Taenia pisiformis), hookworms (Ancylostoma caninum and Uncinaria stenocephala), roundworms (Toxocara canis and Toxascaris leonina), and whipworms (Trichuris vulpis).

The tablets are available in three sizes, each scored for easy administration. Quad Dewormer is manufactured by Elanco US Inc. and is approved by the FDA, ensuring its safety and efficacy for your pet.

Uses

This medication is designed specifically for dogs, particularly large breeds weighing 45 pounds or more. It effectively treats a variety of common intestinal parasites that can affect your pet's health.

You can use this treatment to eliminate common tapeworms, such as Dipylidium caninum and Taenia pisiformis, as well as hookworms like Ancylostoma caninum and Uncinaria stenocephala. It also targets roundworms, including Toxocara canis and Toxascaris leonina, and whipworms, specifically Trichuris vulpis. Keeping your dog free from these parasites is essential for their overall well-being.

Dosage and Administration

You can give Quad Dewormer Chewable Tablets to your dog by placing the tablet directly in their mouth or mixing it with a small amount of food. Before administering the medication, make sure to weigh your dog to determine the correct dosage based on their size.

For puppies and small dogs weighing between 2 and 25 pounds, the dosage varies: if your dog weighs 2 to 4 pounds, give them half a tablet; for 5 to 7 pounds, one tablet; for 8 to 12 pounds, one and a half tablets; for 13 to 18 pounds, two tablets; and for 19 to 25 pounds, two and a half tablets. If your dog is medium-sized, between 26 and 60 pounds, the dosage is one tablet for 26 to 30 pounds, one and a half tablets for 31 to 44 pounds, and two tablets for 45 to 60 pounds. For large dogs weighing 45 pounds and above, give one tablet for 45 to 60 pounds, one and a half tablets for 61 to 90 pounds, and two tablets for 91 to 120 pounds. You don’t need to fast your dog before giving them the medication.

What to Avoid

It's important to ensure the health and safety of your dog or puppy when considering deworming treatments. You should never deworm a dog or puppy that is sick, and this treatment is not suitable for puppies younger than 3 weeks old or dogs that weigh less than 2 pounds.

Additionally, if your pet is weak or debilitated, please consult your veterinarian before giving them any deworming tablets. This will help ensure that your pet receives the appropriate care and treatment they need.

Side Effects

You may experience some side effects after treatment, although they are rare. There have been isolated reports of vomiting, bloody stool, or watery/profuse stool. If you notice any of these symptoms and they continue, it’s important to consult your veterinarian for further guidance.

Warnings and Precautions

It's important to keep this medication out of reach of children to prevent accidental ingestion, which can be dangerous. Always store it in a safe place where children cannot access it.

If you have any concerns or questions about the medication, or if you notice any unusual symptoms, be sure to contact your doctor for guidance. Your health and safety are the top priority, so don’t hesitate to seek help if needed.

Overdose

It appears that there is no specific information available regarding overdosage for this medication. However, it's important to be aware of the general signs of an overdose, which can include symptoms like extreme drowsiness, confusion, or difficulty breathing. If you suspect an overdose, it is crucial to seek immediate medical help.

In case of an emergency, call your local emergency number or go to the nearest hospital. Always keep medications out of reach of children and follow the prescribed dosage to prevent any potential risks. If you have any concerns or questions about your medication, don’t hesitate to reach out to your healthcare provider for guidance.

Pregnancy Use

If you are considering using Quad Dewormer (praziquantel/pyrantel pamoate/febantel) for your pregnant dog, it's important to know that its safety and effectiveness during pregnancy have not been established. This means that the potential risks to the developing puppies have not been fully evaluated. Therefore, it is crucial to consult your veterinarian before giving this medication to your pregnant dog, as they can help you weigh the benefits against any possible risks.

In general, avoid using Quad Dewormer in pregnant dogs unless your veterinarian determines that the benefits outweigh the risks. Always prioritize the health and safety of both the mother and her puppies by seeking professional guidance.

Lactation Use

If you are breastfeeding, it's important to know that there is no specific information available regarding the use of this medication while nursing. This means that the effects on breast milk production or the nursing infant have not been clearly studied or documented.

As always, it's best to consult with your healthcare provider about any medications you are considering while breastfeeding to ensure the safety and well-being of both you and your baby.

Pediatric Use

When considering medication for your dog, it's important to know that this product should not be given to puppies younger than 3 weeks old or to dogs that weigh less than 2 pounds. If you have a puppy or a small dog weighing between 2 and 25 pounds, you can administer the medication based on their weight. For example, a puppy weighing 2 to 4 pounds should receive half a tablet, while a dog weighing 19 to 25 pounds can take 2.5 tablets.

You do not need to fast your dog before giving this medication, so you can administer it at any time. Always ensure you follow the weight guidelines closely to provide the correct dosage for your pet's safety and well-being.

Geriatric Use

It's important to consult your veterinarian before giving these tablets to older dogs or those that seem weak or unwell. Older pets may have different health needs, and your vet can help determine if the medication is safe for them.

Additionally, if your dog or puppy is sick, do not attempt to deworm them without first consulting your veterinarian. They can provide a proper diagnosis and recommend the best course of action for your pet's health. Taking these precautions can help ensure your furry friend receives the care they need.

Renal Impairment

If you have kidney problems, it's important to know that there are no specific guidelines or dosage adjustments mentioned for your condition in the available information. This means that there are no special monitoring requirements or safety considerations outlined for patients like you with renal impairment (kidney issues).

Always consult your healthcare provider for personalized advice and to ensure that any medications you take are safe and appropriate for your situation. They can provide guidance tailored to your health needs.

Hepatic Impairment

If you have liver problems, it's important to know that the drug insert does not provide specific information about dosage adjustments, special monitoring, or precautions for your condition. This means that there are no tailored guidelines for how this medication may affect you if you have hepatic impairment (liver issues).

Always consult your healthcare provider for personalized advice and to discuss any concerns regarding your liver health and how it may relate to your treatment. They can help ensure that you receive the safest and most effective care.

Drug Interactions

It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. While there are no specific drug interactions or laboratory test interactions noted for this medication, your healthcare provider can help ensure that everything you are taking works well together and is safe for you.

Always feel free to ask questions and share your complete list of medications and any lab tests you may be undergoing. This way, you can avoid any potential issues and receive the best care possible.

Storage and Handling

To ensure the best quality and safety of your product, store it at or below 77 °F (25 °C). If you have un-blistered whole or partial tablets, keep them in a tightly sealed container to protect them from moisture and contamination. This will help maintain their effectiveness and prevent any potential issues during use.

Always handle the product with clean hands and avoid exposing it to extreme temperatures or direct sunlight. Proper storage and handling are key to ensuring your product remains safe and effective for your needs.

Additional Information

You can give Quad Dewormer Chewable Tablets for Dogs directly in your dog's mouth or mix them with a small amount of food. It's important to consult your veterinarian for help with diagnosing and treating parasitism, especially before giving the tablets to weak or sick animals. If your dog is unwell, do not attempt to deworm them without veterinary advice.

While fasting your dog before treatment is not necessary, be aware that some dogs may experience side effects such as vomiting or changes in stool (like bloody or watery stools) after taking the medication. If you notice any of these symptoms and they persist, reach out to your veterinarian for guidance.

FAQ

What is Quad Dewormer?

Quad Dewormer is a chewable tablet for dogs that contains praziquantel, pyrantel pamoate, and febantel, designed to remove various types of intestinal worms.

What types of worms does Quad Dewormer treat?

Quad Dewormer treats common tapeworms (Dipylidium caninum and Taenia pisiformis), hookworms (Ancylostoma caninum and Uncinaria stenocephala), roundworms (Toxocara canis and Toxascaris leonina), and whipworms (Trichuris vulpis).

How should I administer Quad Dewormer to my dog?

You can give Quad Dewormer directly in your dog's mouth or mix it with a small amount of food. Ensure you weigh your dog to determine the correct dosage.

What is the recommended dosage for large dogs?

For large dogs (45 lbs and greater), the dosage is 1.0 tablet for 45-60 lbs, 1.5 tablets for 61-90 lbs, and 2.0 tablets for 91-120 lbs.

Are there any contraindications for using Quad Dewormer?

Do not use Quad Dewormer in puppies less than 3 weeks of age or dogs weighing less than 2 lbs. Also, do not deworm a sick dog without consulting a veterinarian.

What should I do if my dog experiences side effects?

If your dog shows signs of vomiting, bloody stool, or watery/profuse stool after treatment, consult your veterinarian if these symptoms persist.

Is Quad Dewormer safe for pregnant dogs?

The safety and efficacy of Quad Dewormer in pregnant dogs have not been established. Consult your veterinarian before use.

How should I store Quad Dewormer?

Store Quad Dewormer at or below 77 °F (25 °C) in a tightly sealed container, and keep it out of reach of children.

Packaging Info

The table below lists each NDC Code for Quad Dewormer (praziquantel, pyrantel pamoate, febantel) veterinary formulations. Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Quad Dewormer.
Details

Drug Information (PDF)

This PDF provides official product information for Quad Dewormer, which is intended for animal use only.

View veterinary product document (PDF)

Description

Each tablet contains 136.0 mg of praziquantel, 136.0 mg of pyrantel base as pyrantel pamoate, and 680.4 mg of febantel.

Uses and Indications

This drug is indicated for the treatment of intestinal parasitic infections in dogs, specifically targeting the following conditions:

  • Common tapeworms, including Dipylidium caninum and Taenia pisiformis.

  • Common hookworms, including Ancylostoma caninum and Uncinaria stenocephala.

  • Common roundworms, including Toxocara canis and Toxascaris leonina.

  • Whipworms, specifically Trichuris vulpis.

This formulation is available as chewable tablets and is specifically intended for use in large dogs weighing 45 pounds or greater.

Dosage and Administration

Quad Dewormer Chewable Tablets for Dogs may be administered directly into the mouth or mixed with a small amount of food to facilitate ingestion. It is essential for the healthcare professional to weigh the dog prior to administration to ensure the correct dosage based on the animal's size.

For administration, the following dosing guidelines should be adhered to:

Puppies and Small Dogs (2 - 25 lbs.):

  • For dogs weighing 2 - 4 lbs: Administer 0.5 tablets.

  • For dogs weighing 5 - 7 lbs: Administer 1.0 tablet.

  • For dogs weighing 8 - 12 lbs: Administer 1.5 tablets.

  • For dogs weighing 13 - 18 lbs: Administer 2.0 tablets.

  • For dogs weighing 19 - 25 lbs: Administer 2.5 tablets.

Medium Dogs (26 - 60 lbs.):

  • For dogs weighing 26 - 30 lbs: Administer 1.0 tablet.

  • For dogs weighing 31 - 44 lbs: Administer 1.5 tablets.

  • For dogs weighing 45 - 60 lbs: Administer 2.0 tablets.

Large Dogs (45 lbs. and greater):

  • For dogs weighing 45 - 60 lbs: Administer 1.0 tablet.

  • For dogs weighing 61 - 90 lbs: Administer 1.5 tablets.

  • For dogs weighing 91 - 120 lbs: Administer 2.0 tablets.

Fasting prior to administration is neither necessary nor recommended.

Contraindications

Deworming is contraindicated in dogs or puppies that are sick. Additionally, this product is not intended for use in puppies less than 3 weeks of age or dogs weighing less than 2 lbs. It is essential to consult a veterinarian before administering the tablets to weak or debilitated animals to ensure their safety and well-being.

Warnings and Precautions

It is imperative to keep this medication out of reach of children to prevent accidental ingestion and potential harm.

Healthcare professionals are advised to educate patients and caregivers about the importance of secure storage practices to mitigate risks associated with pediatric exposure. Regular reminders about the necessity of safeguarding medications can enhance patient safety and compliance.

Side Effects

Adverse reactions have been observed in patients following treatment, with isolated incidents of vomiting, bloody stool, or watery/profuse stool reported. In the event that these signs are observed and persist, it is advised that patients consult their veterinarian for further evaluation and management.

Drug Interactions

There are currently no documented drug interactions associated with this medication. Additionally, there are no known interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.

Packaging & NDC

The table below lists each NDC Code for Quad Dewormer (praziquantel, pyrantel pamoate, febantel) veterinary formulations. Columns show Packaging, Formulation Type, and Active Ingredient Strength.

Packaging configurations for Quad Dewormer.
Details

Pediatric Use

Pediatric patients should not be treated with this medication if they are puppies less than 3 weeks of age or dogs weighing less than 2 lbs. For those eligible, the following dosing guidelines apply for puppies and small dogs weighing between 2 and 25 lbs:

  • For dogs weighing 2 - 4 lbs: 0.5 tablets

  • For dogs weighing 5 - 7 lbs: 1.0 tablet

  • For dogs weighing 8 - 12 lbs: 1.5 tablets

  • For dogs weighing 13 - 18 lbs: 2.0 tablets

  • For dogs weighing 19 - 25 lbs: 2.5 tablets

It is important to note that fasting prior to administration is neither necessary nor recommended.

Geriatric Use

Elderly patients may present unique challenges when administering medications, particularly in cases involving weak or debilitated conditions. It is essential for healthcare providers to consult with a veterinarian prior to administering the tablets to ensure the safety and appropriateness of treatment in these populations.

Additionally, it is critical to avoid deworming dogs or puppies that are exhibiting signs of illness. A thorough veterinary consultation is recommended to obtain an accurate diagnosis of the underlying condition and to determine the most suitable course of care. This approach helps to mitigate potential risks associated with treatment in geriatric patients.

Pregnancy

Safety and efficacy of Quad Dewormer (praziquantel/pyrantel pamoate/febantel) in pregnant dogs have not been established. The use of this medication in pregnant dogs is contraindicated unless the benefits outweigh the risks. Potential risks to the fetus have not been fully evaluated; therefore, it is essential for healthcare professionals to consult a veterinarian for guidance before administration. Special precautions should be taken when considering treatment in pregnant dogs, emphasizing the importance of a thorough risk assessment.

Lactation

There is no specific information available regarding the use of this medication in nursing mothers. Additionally, no lactation considerations, precautions, or modifications for women who are breastfeeding have been provided. Healthcare professionals should exercise caution and consider the potential risks and benefits when prescribing this medication to lactating mothers.

Renal Impairment

Patients with renal impairment have not been specifically addressed in the available data regarding dosage adjustments, special monitoring, or safety considerations. Therefore, healthcare professionals should exercise caution when prescribing this medication to patients with reduced kidney function, as the lack of information necessitates careful clinical judgment and monitoring of these patients.

Hepatic Impairment

Patients with hepatic impairment have not been specifically studied in relation to the use of this medication. Consequently, there are no established dosage adjustments, special monitoring requirements, or precautions outlined for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be prudent in these cases, although specific parameters are not defined in the available information.

Overdosage

There is currently no specific information available regarding overdosage for this medication. Healthcare professionals are advised to monitor patients closely for any signs of adverse effects or symptoms that may arise from excessive dosing.

In the event of suspected overdosage, it is recommended that healthcare providers initiate supportive care and symptomatic treatment as necessary. Patients should be evaluated for potential complications, and appropriate interventions should be implemented based on clinical judgment.

For further guidance, healthcare professionals may refer to established protocols for managing drug overdosage or consult a poison control center.

Nonclinical Toxicology

No information is available regarding teratogenic effects. Additionally, there is no information provided concerning non-teratogenic effects. The insert does not contain any details related to nonclinical toxicology. Furthermore, there is no information available regarding animal pharmacology and toxicology.

Postmarketing Experience

Isolated incidents of vomiting, bloody stool, or watery/profuse stool have been reported following treatment. In cases where these signs are observed and persist, it is advised to consult a veterinarian. For inquiries or to report a suspected side effect, individuals may contact Elanco at 888-545-5973.

Patient Counseling

Healthcare providers should advise patients to consult their veterinarian for assistance in the diagnosis, treatment, and control of parasitism in their pets. It is important to emphasize that patients should seek veterinary guidance before administering the tablets to weak or debilitated animals. Additionally, patients must be informed not to deworm a dog or puppy that is sick and to consult their veterinarian for a proper diagnosis of the illness and appropriate care.

Patients should be instructed to weigh their dog to ensure they are using the correct size and number of tablets for effective treatment. It is also essential to communicate that fasting is neither necessary nor recommended prior to administration of the medication.

Healthcare providers should discuss the importance of taking steps to control fleas and rodents on the premises to prevent reinfection, as failure to do so may necessitate retreatment. Patients should be made aware that if reinfection occurs, tapeworm segments may be observed within one month of the initial treatment.

Instruct patients to monitor their pets for any signs of adverse reactions, such as vomiting, bloody stool, or watery/profuse stool, and to consult their veterinarian if these symptoms persist. For any questions or to report a suspected side effect, patients should be directed to contact Elanco at 888-545-5973.

Storage and Handling

The product is supplied in various package configurations, with specific NDC numbers available for identification. It is essential to store the product at or below 77 °F (25 °C) to maintain its efficacy. Un-blistered whole or partial tablets must be kept in a tightly sealed container to ensure their stability and prevent contamination. Proper adherence to these storage conditions is crucial for preserving the quality of the product.

Additional Clinical Information

Quad Dewormer Chewable Tablets for Dogs can be administered directly into the mouth or mixed with a small amount of food. Clinicians are advised to counsel pet owners to consult their veterinarian for the diagnosis, treatment, and control of parasitism. It is important to seek veterinary advice before administering the tablets to weak or debilitated animals, and to avoid deworming dogs or puppies that are ill, as proper diagnosis and care are essential.

Fasting prior to administration is neither necessary nor recommended. Postmarketing experience has indicated isolated incidents of vomiting, bloody stool, or watery/profuse stool following treatment. If these symptoms occur and persist, pet owners should consult their veterinarian for further evaluation.

Drug Information (PDF)

This document includes the full labeling information for Quad Dewormer, as submitted by Elanco US Inc. for veterinary use. It may include dosage by species, withdrawal periods, and administration instructions.

View veterinary label (PDF)

Data Generation & Sources

This veterinary label for Quad Dewormer was retrieved from DailyMed on by a validated AI data-extraction workflow.

AI data-extraction workflow. All FDA-approved animal dosage forms and strengths are listed in the Packaging & NDC Codes section above. Regulatory metadata shown on this page is reproduced directly from the FDA Structured Product Label and the NSDE NDC Directory daily file.

Note: an automated daemon monitors NSDE checksums; when the record for this NDC changes, the new file is pulled instantly and this page is refreshed.

No human clinician has reviewed this version.

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Regulatory data notice: Information on this page is reproduced verbatim from FDA public databases (NSDE, Orange Book, Purple Book, DailyMed SPL). NDA/ANDA drugs are FDA-approved, BLA biologics are FDA-licensed. Inclusion alone does not guarantee current market availability or imply FDA endorsement.

Medical disclaimer: This AI-generated content is provided for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare professional for diagnosis or treatment decisions.