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Refresh Optive Mega-3 Pf
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- Active ingredients
- Glycerin 10 mg/1 mL
- Carboxymethylcellulose Sodium 5 mg/1 mL
- Polysorbate 80 5 mg/1 mL
- Other brand names
- Drug class
- Non-Standardized Chemical Allergen
- Dosage form
- Solution/ Drops
- Route
- Ophthalmic
- Prescription status
- OTC (over the counter)
- Pregnancy
- See Pregnancy Use Section
- Lactation
- See Lactation Use Section
- Marketed in the U.S.
- Since 2026
- Label revision date
- March 1, 2026
- Drug Information (PDF)
- Prescribing information, PDF file
- Active ingredients
- Glycerin 10 mg/1 mL
- Carboxymethylcellulose Sodium 5 mg/1 mL
- Polysorbate 80 5 mg/1 mL
- Other brand names
- Drug class
- Non-Standardized Chemical Allergen
- Dosage form
- Solution/ Drops
- Route
- Ophthalmic
- Prescription status
- OTC (over the counter)
- CSA schedule
- Not a scheduled drug
- Pregnancy
- See Pregnancy Use Section
- Lactation
- See Lactation Use Section
- Marketed in the U.S.
- Since 2026
- Label revision date
- March 1, 2026
- Manufacturer
- Allergan, Inc.
- Registration number
- M018
- NDC root
- 0023-3988
- Drug Information (PDF)
- Prescribing information, PDF file
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If you are a consumer or patient please visit this version.
Drug Overview
Refresh OPTIVE MEGA-3® PF is a type of lubricant eye drop designed to provide temporary relief from burning, irritation, and discomfort caused by dry eyes or exposure to environmental factors like wind or sun. These eye drops are preservative-free and enhanced with flaxseed oil, which helps to soothe and protect your eyes from further irritation.
This fast-acting formulation is ideal for anyone experiencing dryness in their eyes, offering a gentle way to keep your eyes comfortable and hydrated.
Uses
If you're experiencing burning, irritation, or discomfort in your eyes due to dryness or exposure to wind or sun, this product can provide temporary relief. It works by soothing your eyes and helping to alleviate those uncomfortable sensations.
Additionally, it may serve as a protective barrier against further irritation, ensuring your eyes stay comfortable in challenging conditions. You can use it to help maintain eye comfort throughout your day.
Dosage and Administration
Before you start using this medication, make sure to read the “Instructions for Use” included in the carton. This will help you understand how to use it properly.
When you're ready to use the drops, simply instill (put) 1 or 2 drops into the affected eye(s) as needed. This means you can use the drops whenever you feel it's necessary for your eye condition.
What to Avoid
It's important to be aware of certain guidelines when using this medication. While there are no specific contraindications or concerns regarding abuse, misuse, or dependence, you should stop using the product and consult your doctor if you experience any eye pain, changes in vision, ongoing redness or irritation, or if your condition worsens or does not improve after 72 hours. Your health and safety are paramount, so don't hesitate to reach out to a healthcare professional if you have any concerns.
Side Effects
You should be aware that this product is for external use only. To prevent contamination, avoid touching the tip of the container to any surface and always replace the cap after use. If you notice any changes in the color of the solution, do not use it.
It's important to stop using the product and consult your doctor if you experience eye pain, changes in vision, or if you notice continued redness or irritation of the eye. If your condition worsens or does not improve within 72 hours, seek medical advice. Additionally, keep this product out of reach of children; if swallowed, seek medical help or contact a Poison Control Center immediately.
Warnings and Precautions
This product is for external use only. To keep it safe and effective, avoid touching the tip of the container to any surface, and always replace the cap after use. If you notice any change in the color of the solution, do not use it.
You should stop using this product and contact your doctor if you experience eye pain, changes in vision, or if you notice continued redness or irritation in your eye. If your condition worsens or does not improve within 72 hours, seek medical advice.
In case of accidental swallowing, it’s important to get emergency medical help or contact a Poison Control Center immediately. Your safety is a priority, so please take these precautions seriously.
Overdose
If you or someone else has swallowed too much of a medication, it’s important to seek medical help immediately. You can do this by contacting a Poison Control Center or going to the nearest emergency room. Acting quickly can make a significant difference in the outcome.
Signs of an overdose can vary, but they may include unusual drowsiness, confusion, or difficulty breathing. If you notice any of these symptoms, don’t hesitate to get help right away. Remember, it’s always better to be safe and get checked by a medical professional.
Pregnancy Use
If you are pregnant or planning to become pregnant, it's important to know that the safety of this product during pregnancy has not been established. While there are no specific contraindications listed, caution is advised since the effects on pregnancy have not been well studied. Currently, there is no detailed information available regarding potential risks to the fetus.
Before using this product, it is essential to consult with your healthcare provider. They can help you understand any potential risks and guide you on the best course of action for your health and the health of your baby.
Lactation Use
If you are breastfeeding, you can use REFRESH OPTIVE MEGA-3 PF without specific warnings or recommendations against it. The information available does not indicate any concerns about the product being passed into breast milk or any risks to your nursing infant.
As always, it's a good idea to consult with your healthcare provider if you have any questions or concerns about using this product while breastfeeding.
Pediatric Use
It's important to keep this medication out of reach of children to prevent accidental ingestion. If your child swallows any of it, seek medical help immediately or contact a Poison Control Center for guidance. Taking these precautions can help ensure your child's safety.
Geriatric Use
When it comes to using REFRESH OPTIVE MEGA-3 PF, there is no specific information available about how it should be used by older adults. This means that there are no special dosage adjustments, safety concerns, or precautions outlined for elderly patients.
If you are an older adult or a caregiver, it's always a good idea to consult with a healthcare professional before starting any new medication. They can provide personalized advice based on individual health needs and conditions.
Renal Impairment
If you have kidney problems, it's important to know that the information provided does not include specific guidelines for dosage adjustments, special monitoring, or safety considerations related to renal impairment (kidney issues). This means that there are no tailored recommendations for how your treatment may need to be adjusted based on your kidney function.
Always consult your healthcare provider for personalized advice and to ensure that your treatment plan is safe and effective for your specific condition. They can help monitor your kidney health and make any necessary changes to your medications.
Hepatic Impairment
If you have liver problems, it's important to know that the information provided does not include specific guidelines for dosage adjustments, special monitoring, or precautions related to your condition. This means that there are no tailored recommendations for how the medication may affect you differently due to your liver health.
Always consult your healthcare provider for personalized advice and to ensure that any treatment plan is safe and effective for your specific situation. They can help determine the best approach based on your liver function and overall health.
Drug Interactions
It's important to have open conversations with your healthcare provider about any medications or tests you may be taking. Currently, there are no specific drug interactions or laboratory test interactions noted for this medication. However, your healthcare provider can help ensure that your treatment plan is safe and effective, taking into account all the medications and tests you may be using. Always feel free to ask questions and share your complete health history to avoid any potential issues.
Storage and Handling
To ensure the safety and effectiveness of your product, make sure to use it only if the tape seals on the top and bottom flaps are intact. Always check the expiration date marked on the container and use the product before that date. Once opened, remember to discard it 90 days later to maintain safety.
For proper storage, keep the product in a cool, dry place at a temperature between 59°F and 77°F (15°C and 25°C). Following these guidelines will help you use the product safely and effectively.
Additional Information
No further information is available.
FAQ
What is Refresh OPTIVE MEGA-3® PF?
Refresh OPTIVE MEGA-3® PF is a preservative-free lubricant eye drop designed for the temporary relief of burning, irritation, and discomfort due to dryness of the eye.
How does Refresh OPTIVE MEGA-3® PF work?
It provides fast-acting dry eye relief and may act as a protectant against further irritation from environmental factors like wind or sun.
What should I do before using Refresh OPTIVE MEGA-3® PF for the first time?
Please read the 'Instructions for Use' inside the carton prior to first use.
How do I use Refresh OPTIVE MEGA-3® PF?
Instill 1 or 2 drops in the affected eye(s) as needed.
Are there any contraindications for using Refresh OPTIVE MEGA-3® PF?
No specific contraindications are listed, but caution is advised if you experience eye pain or changes in vision.
What should I do if I experience side effects?
Stop use and ask a doctor if you experience eye pain, changes in vision, continued redness or irritation, or if the condition worsens or persists for more than 72 hours.
Is Refresh OPTIVE MEGA-3® PF safe to use during pregnancy?
The safety of this product during pregnancy has not been established, so consult a healthcare provider before use if pregnant or planning to become pregnant.
Can I use Refresh OPTIVE MEGA-3® PF while nursing?
There are no specific warnings or recommendations regarding its use in nursing mothers mentioned in the insert.
How should I store Refresh OPTIVE MEGA-3® PF?
Store it at 59°-77°F (15°-25°C) and discard 90 days after opening.
What should I do if I accidentally swallow Refresh OPTIVE MEGA-3® PF?
If swallowed, get medical help or contact a Poison Control Center right away.
Packaging Info
Below are the non-prescription pack sizes of Refresh Optive Mega-3 Pf (carboxymethylcellulose sodium, glycerin, polysorbate 80). Columns show Packaging, Formulation Type, and Active Ingredient Strength.
Details | ||||
|---|---|---|---|---|
| Solution/ Drops |
| ||
Product details Regulatory status — Marketed All current FDA data sets list this NDC as actively marketed. FDA record dates for this NDC:
Active ingredients
Inactive ingredients
| ||||
Drug Information (PDF)
This file contains official product information for Refresh Optive Mega-3 Pf, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.
Description
No description information is available for the drug.
Uses and Indications
This drug is indicated for the temporary relief of burning, irritation, and discomfort associated with dryness of the eye or exposure to environmental factors such as wind or sun. It may also be utilized as a protectant against further irritation.
There are no teratogenic or nonteratogenic effects associated with this drug.
Dosage and Administration
Prior to the first use, healthcare professionals should instruct patients to read the “Instructions for Use” included within the carton. The recommended dosage is to instill 1 or 2 drops into the affected eye(s) as needed.
Contraindications
Use is contraindicated in patients who experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours. In such cases, it is advised to discontinue use and consult a healthcare professional.
Warnings and Precautions
External use of this product is strictly advised. To prevent contamination, healthcare professionals should instruct patients to avoid contact between the tip of the container and any surface. It is essential to replace the cap immediately after use to maintain product integrity. Should the solution exhibit any color change, it must not be used.
Patients should be advised to discontinue use and consult a physician if they experience any of the following symptoms: eye pain, alterations in vision, persistent redness or irritation of the eye, or if the condition does not improve or worsens after 72 hours.
In cases of accidental ingestion, immediate medical assistance should be sought. Patients or caregivers are encouraged to contact a Poison Control Center without delay to ensure appropriate management.
Side Effects
Patients using this product should be aware of several important warnings and potential adverse reactions. The product is intended for external use only. To prevent contamination, patients are advised not to touch the tip of the container to any surface and to replace the cap after each use.
In the event that the solution changes color, it should not be used. Patients are instructed to stop using the product and consult a doctor if they experience any of the following: eye pain, changes in vision, continued redness or irritation of the eye, or if their condition worsens or persists for more than 72 hours.
Additionally, this product should be kept out of reach of children. If swallowed, it is crucial to seek medical help or contact a Poison Control Center immediately.
Drug Interactions
There are currently no documented drug interactions associated with this medication. Additionally, there is no information available regarding interactions with laboratory tests. As such, no specific recommendations for dosage adjustments or monitoring are warranted at this time.
Packaging & NDC
Below are the non-prescription pack sizes of Refresh Optive Mega-3 Pf (carboxymethylcellulose sodium, glycerin, polysorbate 80). Columns show Packaging, Formulation Type, and Active Ingredient Strength.
Details | ||||
|---|---|---|---|---|
| Solution/ Drops |
| ||
Product details Regulatory status — Marketed All current FDA data sets list this NDC as actively marketed. FDA record dates for this NDC:
Active ingredients
Inactive ingredients
| ||||
Pediatric Use
Pediatric patients should be advised to keep this medication out of reach of children. In the event of accidental ingestion, immediate medical assistance should be sought, or contact with a Poison Control Center is recommended.
Geriatric Use
There is no specific information regarding the use of REFRESH OPTIVE MEGA-3 PF in geriatric patients, including dosage adjustments, safety concerns, or special precautions. Healthcare providers should exercise caution when prescribing this medication to elderly patients, as individual responses may vary. Monitoring for any adverse effects or changes in efficacy is advisable in this population.
Pregnancy
The safety of this product during pregnancy has not been established. Caution is advised as the effects on pregnancy are not well studied, and no specific information regarding risks to the fetus is provided. Healthcare providers should be consulted before use in pregnant patients or those planning to become pregnant. There are no specific dosage modifications for pregnant individuals mentioned in the available data.
Lactation
There are no specific warnings or recommendations regarding the use of REFRESH OPTIVE MEGA-3 PF in lactating mothers. Additionally, there is no information available concerning the potential for excretion of REFRESH OPTIVE MEGA-3 PF in breast milk or any associated risks to breastfed infants.
Renal Impairment
Patients with renal impairment have not been specifically addressed in the prescribing information regarding dosage adjustments, special monitoring, or safety considerations. Therefore, healthcare professionals should exercise caution when prescribing this medication to patients with reduced kidney function, as the absence of detailed guidance necessitates careful clinical judgment and monitoring of these patients.
Hepatic Impairment
Patients with hepatic impairment have not been specifically studied in clinical trials for this medication. Consequently, there is no available information regarding dosage adjustments, special monitoring requirements, or precautions for individuals with compromised liver function. It is recommended that healthcare providers exercise caution when prescribing this medication to patients with hepatic impairment, given the lack of data on its safety and efficacy in this population. Regular monitoring of liver function may be warranted based on clinical judgment.
Overdosage
In the event of an overdosage, immediate medical intervention is crucial. If the substance is ingested, it is imperative to seek medical assistance or contact a Poison Control Center without delay.
Healthcare professionals should be aware that prompt action can significantly influence the outcome of an overdosage situation. Symptoms of overdosage may vary depending on the specific substance involved; therefore, a thorough assessment and monitoring of the patient are essential.
Management procedures may include supportive care and symptomatic treatment, tailored to the individual patient's needs. Continuous evaluation and appropriate interventions should be implemented based on the clinical presentation and severity of symptoms.
In all cases of suspected overdosage, the involvement of poison control experts is recommended to guide the management process effectively.
Nonclinical Toxicology
No teratogenic or non-teratogenic effects have been reported in the available nonclinical studies. Additionally, there is no information regarding animal pharmacology and toxicology. The absence of data limits the assessment of potential risks associated with the compound in these areas.
Postmarketing Experience
No postmarketing experience details are available in the provided text.
Patient Counseling
Healthcare providers should advise patients to keep the medication out of reach of children to prevent accidental ingestion. In the event that the medication is swallowed, patients should be instructed to seek medical help or contact a Poison Control Center immediately.
Additionally, patients should be informed to discontinue use and consult their doctor if they experience any of the following: eye pain, changes in vision, persistent redness or irritation of the eye, or if their condition worsens or does not improve after 72 hours. This guidance is essential to ensure patient safety and effective management of their condition.
Storage and Handling
The product is supplied in containers that must be used only if the tape seals on the top and bottom flaps are intact. It is essential to adhere to the expiration date marked on the container, ensuring that the product is utilized before this date. Once opened, the product should be discarded 90 days after opening to maintain safety and efficacy.
Storage conditions require the product to be kept at a temperature range of 59°-77°F (15°-25°C). Proper handling and storage are crucial to ensure the integrity of the product throughout its shelf life.
Additional Clinical Information
No further data are available.
Drug Information (PDF)
This file contains official product information for Refresh Optive Mega-3 Pf, including active ingredients, dosage, warnings, and labeling as submitted by the manufacturer for OTC distribution.